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Items: 1 to 20 of 31

1.
ICA1 affects APP processing through the PICK1‐PKCα signaling pathway
Liangye Ji, ZiJun Meng, Xiangjun Dong, Qunxian Wang, Yanshuang Jiang, Jie Zhang, Dongjie Hu, Shipeng Guo, Weihui Zhou, Weihong Song
CNS Neurosci Ther. 2024 Jun; 30(6): e14754. Published online 2024 Jun 17. doi: 10.1111/cns.14754
PMCID:
PMC11181291
AbstractArticlePDF–9.1M
2.
Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets
Filip Mihalič, Caroline Benz, Eszter Kassa, Richard Lindqvist, Leandro Simonetti, Raviteja Inturi, Hanna Aronsson, Eva Andersson, Celestine N. Chi, Norman E. Davey, Anna K. Överby, Per Jemth, Ylva Ivarsson
Nat Commun. 2023; 14: 5636. Published online 2023 Sep 13. doi: 10.1038/s41467-023-41312-8
PMCID:
PMC10499821
AbstractArticlePDF–2.6M
3.
WWP1 upregulation predicts poor prognosis and promotes tumor progression by regulating ubiquitination of NDFIP1 in intrahepatic cholangiocarcinoma
Yongjian Li, Qian Cheng, Jie Gao, Zhuomiaoyu Chen, Jingheng Guo, Zuyin Li, Lingyu Tian, Chao Zhang, Yuzi Li, Jiaxi Zheng, Zhao Li, Jiye Zhu
Cell Death Discov. 2022; 8: 107. Published online 2022 Mar 9. doi: 10.1038/s41420-022-00882-0
PMCID:
PMC8906119
AbstractArticlePDF–6.1M
4.
An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity
Yuehui Zhang, Limin Shang, Jing Zhang, Yuchen Liu, Chaozhi Jin, Yanan Zhao, Xiaobo Lei, Wenjing Wang, Xia Xiao, Xiuyuan Zhang, Yujiao Liu, Linlin Liu, Meng-Wei Zhuang, Qingkun Mi, Chunyan Tian, Jianwei Wang, Fuchu He, Pei-Hui Wang, Jian Wang
Cell Chem Biol. 2022 Jan 20; 29(1): 5–18.e6. Published online 2021 Oct 20. doi: 10.1016/j.chembiol.2021.10.008
PMCID:
PMC8527578
AbstractArticlePDF–4.5M
5.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
6.
Novel SRF-ICA1L Fusions in Cellular Myoid Neoplasms with Potential for Malignant Behavior
Albert J. Suurmeijer, Brendan C. Dickson, David Swanson, Yun-Shao Sung, Lei Zhang, Cristina R. Antonescu
Am J Surg Pathol. Author manuscript; available in PMC 2021 Jan 1.
Published in final edited form as: Am J Surg Pathol. 2020 Jan; 44(1): 55–60. doi: 10.1097/PAS.0000000000001336
PMCID:
PMC6904430
AbstractArticlePDF–1.4M
7.
An interactome perturbation framework prioritizes damaging missense mutations for developmental disorders
Siwei Chen, Robert Fragoza, Lambertus Klei, Yuan Liu, Jiebiao Wang, Kathryn Roeder, Bernie Devlin, Haiyuan Yu
Nat Genet. Author manuscript; available in PMC 2019 Jul 1.
Published in final edited form as: Nat Genet. 2018 Jul; 50(7): 1032–1040. Published online 2018 Jun 11. doi: 10.1038/s41588-018-0130-z
PMCID:
PMC6314957
AbstractArticlePDF–1.3M
8.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M
9.
Panorama of ancient metazoan macromolecular complexes
Cuihong Wan, Blake Borgeson, Sadhna Phanse, Fan Tu, Kevin Drew, Greg Clark, Xuejian Xiong, Olga Kagan, Julian Kwan, Alexandr Berzginov, Kyle Chessman, Swati Pal, Graham Cromar, Ophelia Papoulas, Zuyao Ni, Daniel R. Boutz, Snejana Stoilova, Pierre C. Havugimana, Xinghua Guo, Ramy H. Malty, Mihail Sarov, Jack Greenblatt, Mohan Babu, Brent Derry, Elisabeth Tillier, John B. Wallingford, John Parkinson, Edward M. Marcotte, Andrew Emili
Nature. Author manuscript; available in PMC 2016 Sep 26.
Published in final edited form as: Nature. 2015 Sep 17; 525(7569): 339–344. Published online 2015 Sep 7. doi: 10.1038/nature14877
PMCID:
PMC5036527
AbstractArticlePDF–4.7M
10.
The BioPlex Network: A Systematic Exploration of the Human Interactome
Edward L. Huttlin, Lily Ting, Raphael J. Bruckner, Fana Gebreab, Melanie P. Gygi, John Szpyt, Stanley Tam, Gabriela Zarraga, Greg Colby, Kurt Baltier, Rui Dong, Virginia Guarani, Laura Pontano Vaites, Alban Ordureau, Ramin Rad, Brian K. Erickson, Martin Wühr, Joel Chick, Bo Zhai, Deepak Kolippakkam, Julian Mintseris, Robert A. Obar, Tim Harris, Spyros Artavanis-Tsakonas, Mathew E. Sowa, Pietro DeCamilli, Joao A. Paulo, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2016 Jul 16.
Published in final edited form as: Cell. 2015 Jul 16; 162(2): 425–440. doi: 10.1016/j.cell.2015.06.043
PMCID:
PMC4617211
AbstractArticlePDF–2.2M
11.
Heritability and genetic association analysis of cognition in the Diabetes Heart Study
Amanda J. Cox, Christina E. Hugenschmidt, Laura M. Raffield, Carl D. Langefeld, Barry I. Freedman, Jeff D. Williamson, Fang-Chi Hsu, Donald W. Bowden
Neurobiol Aging. Author manuscript; available in PMC 2015 May 4.
Published in final edited form as: Neurobiol Aging. 2014 Aug; 35(8): 1958.e3–1958.e12. Published online 2014 Mar 11. doi: 10.1016/j.neurobiolaging.2014.03.005
PMCID:
PMC4418030
AbstractArticlePDF–1.5M
12.
A proteome-scale map of the human interactome network
Thomas Rolland, Murat Taşan, Benoit Charloteaux, Samuel J. Pevzner, Quan Zhong, Nidhi Sahni, Song Yi, Irma Lemmens, Celia Fontanillo, Roberto Mosca, Atanas Kamburov, Susan D. Ghiassian, Xinping Yang, Lila Ghamsari, Dawit Balcha, Bridget E. Begg, Pascal Braun, Marc Brehme, Martin P. Broly, Anne-Ruxandra Carvunis, Dan Convery-Zupan, Roser Corominas, Jasmin Coulombe-Huntington, Elizabeth Dann, Matija Dreze, Amélie Dricot, Changyu Fan, Eric Franzosa, Fana Gebreab, Bryan J. Gutierrez, Madeleine F. Hardy, Mike Jin, Shuli Kang, Ruth Kiros, Guan Ning Lin, Katja Luck, Andrew MacWilliams, Jörg Menche, Ryan R. Murray, Alexandre Palagi, Matthew M. Poulin, Xavier Rambout, John Rasla, Patrick Reichert, Viviana Romero, Elien Ruyssinck, Julie M. Sahalie, Annemarie Scholz, Akash A. Shah, Amitabh Sharma, Yun Shen, Kerstin Spirohn, Stanley Tam, Alexander O. Tejeda, Shelly A. Wanamaker, Jean-Claude Twizere, Kerwin Vega, Jennifer Walsh, Michael E. Cusick, Yu Xia, Albert-László Barabási, Lilia M. Iakoucheva, Patrick Aloy, Javier De Las Rivas, Jan Tavernier, Michael A. Calderwood, David E. Hill, Tong Hao, Frederick P. Roth, Marc Vidal
Cell. Author manuscript; available in PMC 2015 Nov 20.
Published in final edited form as: Cell. 2014 Nov 20; 159(5): 1212–1226. doi: 10.1016/j.cell.2014.10.050
PMCID:
PMC4266588
AbstractArticlePDF–3.1M
13.
Genome-Wide Association Study of a Heart Failure-Related Metabolomic Profile among African Americans in the Atherosclerosis Risk in Communities (ARIC) Study
Bing Yu, Yan Zheng, Danny Alexander, Teri A. Manolio, Alvaro Alonso, Jennifer A. Nettleton, Eric Boerwinkle
Genet Epidemiol. Author manuscript; available in PMC 2014 Jul 2.
Published in final edited form as: Genet Epidemiol. 2013 Dec; 37(8): 840–845. Published online 2013 Aug 11. doi: 10.1002/gepi.21752
PMCID:
PMC4079107
AbstractArticlePDF–269K
14.
Genome-wide association study of intraocular pressure identifies the GLCCI1/ICA1 region as a glaucoma susceptibility locus
The Blue Mountains Eye Study (BMES) and The Wellcome Trust Case Control Consortium 2 (WTCCC2), Amy Strange, Céline Bellenguez, Xueling Sim, Robert Luben, Pirro G. Hysi, Wishal D. Ramdas, Leonieke M.E. van Koolwijk, Colin Freeman, Matti Pirinen, Zhan Su, Gavin Band, Richard Pearson, Damjan Vukcevic, Cordelia Langford, Panos Deloukas, Sarah Hunt, Emma Gray, Serge Dronov, Simon C. Potter, Avazeh Tashakkori-Ghanbaria, Sarah Edkins, Suzannah J. Bumpstead, Jenefer M. Blackwell, Elvira Bramon, Matthew A. Brown, Juan P. Casas, Aiden Corvin, Audrey Duncanson, Janusz A.Z. Jankowski, Hugh S. Markus, Christopher G. Mathew, Colin N.A. Palmer, Robert Plomin, Anna Rautanen, Stephen J. Sawcer, Richard C. Trembath, Nicholas W. Wood, Ines Barroso, Leena Peltonen, Paul Healey, Peter McGuffin, Fotis Topouzis, Caroline C.W. Klaver, Cornelia M. van Duijn, David A. Mackey, Terri L. Young, Christopher J. Hammond, Kay-Tee Khaw, Nick Wareham, Jie Jin Wang, Tien Y. Wong, Paul J. Foster, Paul Mitchell, Chris C.A. Spencer, Peter Donnelly, Ananth C. Viswanathan
Hum Mol Genet. 2013 Nov 15; 22(22): 4653–4660. Published online 2013 Jul 7. doi: 10.1093/hmg/ddt293
PMCID:
PMC3904806
AbstractArticlePDF–286K
15.
C-Terminal Domain of ICA69 Interacts with PICK1 and Acts on Trafficking of PICK1-PKCα Complex and Cerebellar Plasticity
Zhen Wang, Ya-Nan Wang, Cheng-Long Sun, Dong Yang, Li-Da Su, Ya-Jun Xie, Lin Zhou, Yin Wang, Ying Shen
PLoS One. 2013; 8(12): e83862. Published online 2013 Dec 16. doi: 10.1371/journal.pone.0083862
PMCID:
PMC3865253
AbstractArticlePDF–4.5M
16.
CBFβ stabilizes HIV Vif to counteract APOBEC3 at the expense of RUNX1 target gene expression
Dong Young Kim, Eunju Kwon, Paul D. Hartley, David C. Crosby, Sumanjit Mann, Nevan J. Krogan, John D. Gross
Mol Cell. Author manuscript; available in PMC 2014 Feb 21.
Published in final edited form as: Mol Cell. 2013 Feb 21; 49(4): 632–644. Published online 2013 Jan 17. doi: 10.1016/j.molcel.2012.12.012
PMCID:
PMC3582769
AbstractArticlePDF–4.5M
17.
Novel Genetic Loci Identified for the Pathophysiology of Childhood Obesity in the Hispanic Population
Anthony G. Comuzzie, Shelley A. Cole, Sandra L. Laston, V. Saroja Voruganti, Karin Haack, Richard A. Gibbs, Nancy F. Butte
PLoS One. 2012; 7(12): e51954. Published online 2012 Dec 14. doi: 10.1371/journal.pone.0051954
PMCID:
PMC3522587
AbstractArticlePDF–130K
18.
Sequence Variation in Promoter of Ica1 Gene, Which Encodes Protein Implicated in Type 1 Diabetes, Causes Transcription Factor Autoimmune Regulator (AIRE) to Increase Its Binding and Down-regulate Expression
Samantha M. Bonner, Susan L. Pietropaolo, Yong Fan, Yigang Chang, Praveen Sethupathy, Michael P. Morran, Megan Beems, Nick Giannoukakis, Giuliana Trucco, Michael O. Palumbo, Michele Solimena, Alberto Pugliese, Constantin Polychronakos, Massimo Trucco, Massimo Pietropaolo
J Biol Chem. 2012 May 18; 287(21): 17882–17893. Published online 2012 Mar 24. doi: 10.1074/jbc.M111.319020
PMCID:
PMC3366781
AbstractArticlePDF–2.2M
19.
TBC-8, a Putative RAB-2 GAP, Regulates Dense Core Vesicle Maturation in Caenorhabditis elegans
Mandy Hannemann, Nikhil Sasidharan, Jan Hegermann, Lena M. Kutscher, Sabine Koenig, Stefan Eimer
PLoS Genet. 2012 May; 8(5): e1002722. Published online 2012 May 24. doi: 10.1371/journal.pgen.1002722
PMCID:
PMC3359978
AbstractArticlePDF–4.5M
20.
Toward an understanding of the protein interaction network of the human liver
Jian Wang, Keke Huo, Lixin Ma, Liujun Tang, Dong Li, Xiaobi Huang, Yanzhi Yuan, Chunhua Li, Wei Wang, Wei Guan, Hui Chen, Chaozhi Jin, Junchen Wei, Wanqiao Zhang, Yongsheng Yang, Qiongming Liu, Ying Zhou, Cuili Zhang, Zhihao Wu, Wangxiang Xu, Ying Zhang, Tao Liu, Donghui Yu, Yaping Zhang, Liang Chen, Dewu Zhu, Xing Zhong, Lixin Kang, Xiang Gan, Xiaolan Yu, Qi Ma, Jing Yan, Li Zhou, Zhongyang Liu, Yunping Zhu, Tao Zhou, Fuchu He, Xiaoming Yang
Mol Syst Biol. 2011; 7: 536. Published online 2011 Oct 11. doi: 10.1038/msb.2011.67
Correction in:
Mol Syst Biol. 2017 Dec; 13(12): 965.
PMCID:
PMC3261708
AbstractArticlePDF–2.0M

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