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Select item 110452211.

Tgif1-deficiency impairs cytoskeletal architecture in osteoblasts by activating PAK3 signaling

Simona Bolamperti, Hiroaki Saito, Sarah Heerdmann, Eric Hesse, Hanna Taipaleenmäki

eLife. 2024; 13: RP94265. Published online 2024 Apr 25. doi: 10.7554/eLife.94265

PMCID:: PMC11045221

Abstract Article PDF–17M

Select item 96414242.

Antagonizing microRNA‐19a/b augments PTH anabolic action and restores bone mass in osteoporosis in mice

Hanna Taipaleenmäki, Hiroaki Saito, Saskia Schröder, Miki Maeda, Ramona Mettler, Matthias Ring, Ewa Rollmann, Andreas Gasser, Carl Haasper, Thorsten Gehrke, Alexander Weiss, Steffen K Grimm, Eric Hesse

EMBO Mol Med. 2022 Nov; 14(11): e13617. Published online 2022 Oct 4. doi: 10.15252/emmm.202013617

PMCID:: PMC9641424

Abstract Article PDF–3.0M

Select item 94409113.

The TFEB-TGIF1 axis regulates EMT in mouse epicardial cells

Elena Astanina, Gabriella Doronzo, Davide Corà, Francesco Neri, Salvatore Oliviero, Tullio Genova, Federico Mussano, Emanuele Middonti, Edoardo Vallariello, Chiara Cencioni, Donatella Valdembri, Guido Serini, Federica Limana, Eleonora Foglio, Andrea Ballabio, Federico Bussolino

Nat Commun. 2022; 13: 5191. Published online 2022 Sep 3. doi: 10.1038/s41467-022-32855-3

PMCID:: PMC9440911

Abstract Article PDF–5.3M

Select item 83132394.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Abstract Article PDF–1.6M

Select item 77015855.

Loss of TG‐Interacting Factor 1 decreases survival in mouse models of myeloid leukaemia

Ling Yan, Utpal P. Davé, Michael Engel, Stephen J. Brandt, Rizwan Hamid

J Cell Mol Med. 2020 Nov; 24(22): 13472–13480. Published online 2020 Oct 15. doi: 10.1111/jcmm.15977

PMCID:: PMC7701585

Abstract Article PDF–939K

Select item 71468746.

Breast cancer bone metastases are attenuated in a Tgif1-deficient bone microenvironment

Marie-Therese Haider, Hiroaki Saito, Jennifer Zarrer, Kevin Uzhunnumpuram, Sankari Nagarajan, Vijayalakshmi Kari, Michael Horn-Glander, Stefan Werner, Eric Hesse, Hanna Taipaleenmäki

Breast Cancer Res. 2020; 22: 34. Published online 2020 Apr 9. doi: 10.1186/s13058-020-01269-8

PMCID:: PMC7146874

Abstract Article PDF–4.1M

Select item 66742677.

Central Roles of the Roof Plate in Telencephalic Development and Holoprosencephaly

Xun Cheng, Ching-mei Hsu, D. Spencer Currle, Jia Sheng Hu, A. James Barkovich, Edwin S. Monuki

J Neurosci. 2006 Jul 19; 26(29): 7640–7649. doi: 10.1523/JNEUROSCI.0714-06.2006

PMCID:: PMC6674267

Abstract Article PDF–1017K

Select item 65960198.

Canonical TGF-β Signaling Negatively Regulates Neuronal Morphogenesis through TGIF/Smad Complex-Mediated CRMP2 Suppression

Hideyuki Nakashima, Keita Tsujimura, Koichiro Irie, Masataka Ishizu, Miao Pan, Tomonori Kameda, Kinichi Nakashima

J Neurosci. 2018 May 16; 38(20): 4791–4810. doi: 10.1523/JNEUROSCI.2423-17.2018

PMCID:: PMC6596019

Abstract Article PDF–8.4M

Select item 65266179.

Loss of the transcriptional repressor TGIF1 results in enhanced Kras-driven development of pancreatic cancer

Ching-Chieh Weng, Mei-Jen Hsieh, Chia-Chen Wu, Yu-Chun Lin, Yan-Shen Shan, Wen-Chun Hung, Li-Tzong Chen, Kuang-Hung Cheng

Mol Cancer. 2019; 18: 96. Published online 2019 May 20. doi: 10.1186/s12943-019-1023-1

PMCID:: PMC6526617

Abstract Article PDF–19M

Select item 644654310.

TGIF transcription factors repress acetyl CoA metabolic gene expression and promote intestinal tumor growth

Anant Shah, Tiffany A. Melhuish, Todd E. Fox, Henry F. Frierson, Jr, David Wotton

Genes Dev. 2019 Apr 1; 33(7-8): 388–402. doi: 10.1101/gad.320127.118

PMCID:: PMC6446543

Abstract Article PDF–12M

Select item 643077311.

TG-interacting factor 1 (Tgif1)-deficiency attenuates bone remodeling and blunts the anabolic response to parathyroid hormone

Hiroaki Saito, Andreas Gasser, Simona Bolamperti, Miki Maeda, Levi Matthies, Katharina Jähn, Courtney L. Long, Hartmut Schlüter, Marcel Kwiatkowski, Vaibhav Saini, Paola Divieti Pajevic, Teresita Bellido, Andre J. van Wijnen, Khalid S. Mohammad, Theresa A. Guise, Hanna Taipaleenmäki, Eric Hesse

Nat Commun. 2019; 10: 1354. Published online 2019 Mar 22. doi: 10.1038/s41467-019-08778-x

PMCID:: PMC6430773

Abstract Article PDF–2.4M

Select item 590077412.

Degradation of the endoplasmic reticulum–anchored transcription factor MyRF by the ubiquitin ligase SCF^Fbxw7 in a manner dependent on the kinase GSK-3

Shogo Nakayama, Kanae Yumimoto, Atsuki Kawamura, Keiichi I. Nakayama

J Biol Chem. 2018 Apr 13; 293(15): 5705–5714. Published online 2018 Feb 22. doi: 10.1074/jbc.RA117.000741

PMCID:: PMC5900774

Abstract Article PDF–1.6M

Select item 579496313.

Link between the causative genes of holoprosencephaly: Zic2 directly regulates Tgif1 expression

Akira Ishiguro, Minoru Hatayama, Maky I. Otsuka, Jun Aruga

Sci Rep. 2018; 8: 2140. Published online 2018 Feb 1. doi: 10.1038/s41598-018-20242-2

PMCID:: PMC5794963

Abstract Article PDF–3.9M

Select item 558071014.

HOXA1 and TALE proteins display cross-regulatory interactions and form a combinatorial binding code on HOXA1 targets

Bony De Kumar, Hugo J. Parker, Ariel Paulson, Mark E. Parrish, Irina Pushel, Narendra Pratap Singh, Ying Zhang, Brian D. Slaughter, Jay R. Unruh, Laurence Florens, Julia Zeitlinger, Robb Krumlauf

Genome Res. 2017 Sep; 27(9): 1501–1512. doi: 10.1101/gr.219386.116

PMCID:: PMC5580710

Abstract Article PDF–18M

Select item 531682615.

Stepwise reprogramming of liver cells to a pancreas progenitor state by the transcriptional regulator Tgif2

Nuria Cerdá-Esteban, Heike Naumann, Silvia Ruzittu, Nancy Mah, Igor M. Pongrac, Corinna Cozzitorto, Angela Hommel, Miguel A. Andrade-Navarro, Ezio Bonifacio, Francesca M. Spagnoli

Nat Commun. 2017; 8: 14127. Published online 2017 Feb 13. doi: 10.1038/ncomms14127

PMCID:: PMC5316826

Abstract Article PDF–2.7M

Select item 531124216.

Tgif1 and Tgif2 Repress Expression of the RabGAP Evi5l

Anoush E. Anderson, Kenichiro Taniguchi, Yi Hao, Tiffany A. Melhuish, Anant Shah, Stephen D. Turner, Ann E. Sutherland, David Wotton

Mol Cell Biol. 2017 Mar 1; 37(5): e00527-16. Prepublished online 2016 Dec 12. Published online 2017 Feb 15. doi: 10.1128/MCB.00527-16

PMCID:: PMC5311242

Abstract Article PDF–3.4M

Select item 525596117.

Genetic and Molecular Analyses indicate independent effects of TGIFs on Nodal and Gli3 in neural tube patterning

Kenichiro Taniguchi, Anoush E Anderson, Tiffany A Melhuish, Anne L Carlton, Arkadi Manukyan, Ann E Sutherland, David Wotton

Eur J Hum Genet. 2017 Feb; 25(2): 208–215. Published online 2016 Dec 7. doi: 10.1038/ejhg.2016.164

PMCID:: PMC5255961

Abstract Article PDF–2.0M

Select item 487149318.

Tgif1 and Tgif2 Regulate Axial Patterning in Mouse

Tiffany A. Melhuish, Kenichiro Taniguchi, David Wotton

PLoS One. 2016; 11(5): e0155837. Published online 2016 May 17. doi: 10.1371/journal.pone.0155837

PMCID:: PMC4871493

Abstract Article PDF–13M

Select item 472833219.

A new model for non-typeable Haemophilus influenzae middle ear infection in the Junbo mutant mouse

Derek Hood, Richard Moxon, Tom Purnell, Caroline Richter, Debbie Williams, Ali Azar, Michael Crompton, Sara Wells, Martin Fray, Steve D. M. Brown, Michael T. Cheeseman

Dis Model Mech. 2016 Jan 1; 9(1): 69–79. doi: 10.1242/dmm.021659

PMCID:: PMC4728332

Abstract Article

Select item 439891420.

TGIF Governs a Feed-Forward Network That Empowers Wnt Signaling to Drive Mammary Tumorigenesis

Ming-Zhu Zhang, Olivier Ferrigno, Zhe Wang, Mutsuko Ohnishi, Céline Prunier, Laurence Levy, Mohammed Razzaque, Williams C. Horne, Damian Romero, Guri Tzivion, Frédéric Colland, Roland Baron, Azeddine Atfi

Cancer Cell. Author manuscript; available in PMC 2016 Apr 13.

Published in final edited form as: Cancer Cell. 2015 Apr 13; 27(4): 547–560. doi: 10.1016/j.ccell.2015.03.002