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Items: 1 to 20 of 139

1.
The Immunostimulatory RNA RN7SL1 Enables CAR-T Cells to Enhance Autonomous and Endogenous Immune Function
Lexus R. Johnson, Daniel Y. Lee, Jacqueline S. Eacret, Darwin Ye, Carl H. June, Andy J. Minn
Cell. Author manuscript; available in PMC 2024 Aug 21.
Published in final edited form as: Cell. 2021 Sep 16; 184(19): 4981–4995.e14. Published online 2021 Aug 30. doi: 10.1016/j.cell.2021.08.004
PMCID:
PMC11338632
AbstractArticlePDF–3.5M
2.
DUSP4 modulates RIG-I- and STING-mediated IRF3-type I IFN response
Huipeng Jiao, Sharmy J. James, Chin Wen Png, Chaoyu Cui, Heng Li, Liang Li, Wan Ni Chia, Nyo Min, Weiyun Li, Carla Claser, Laurent Rénia, Hongyan Wang, Mark I-Cheng Chen, Justin Jang Hann Chu, Kevin Shyong Wei Tan, Yinyue Deng, Yongliang Zhang
Cell Death Differ. 2024 Mar; 31(3): 280–291. Published online 2024 Feb 21. doi: 10.1038/s41418-024-01269-7
PMCID:
PMC10923883
AbstractArticlePDF–2.8M
3.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
4.
CD97 negatively regulates the innate immune response against RNA viruses by promoting RNF125-mediated RIG-I degradation
Huasong Chang, Peili Hou, Xuefeng Wang, Aibiao Xiang, Hao Wu, Wenjing Qi, Rukun Yang, Xue Wang, Xingyu Li, Wenqi He, Guimin Zhao, Weiyang Sun, Tiecheng Wang, Daniel Chang He, Hongmei Wang, Yuwei Gao, Hongbin He
Cell Mol Immunol. 2023 Dec; 20(12): 1457–1471. Published online 2023 Nov 17. doi: 10.1038/s41423-023-01103-z
PMCID:
PMC10687259
AbstractArticlePDF–5.8M
5.
MAVS-loaded unanchored Lys63-linked polyubiquitin chains activate the RIG-I-MAVS signaling cascade
Feng Liu, Wanxin Zhuang, Bin Song, Yuan Yang, Junqi Liu, Yi Zheng, Bingyu Liu, Jie Zheng, Wei Zhao, Chengjiang Gao
Cell Mol Immunol. 2023 Oct; 20(10): 1186–1202. Published online 2023 Aug 15. doi: 10.1038/s41423-023-01065-2
PMCID:
PMC10542333
AbstractArticlePDF–6.3M
6.
TTC6-Mediated Stabilization of the Flagellum Annulus Ensures the Rapid and Directed Motion of Sperm
Ziqi Wang, Kailun Fang, Yanling Wan, Yingying Yin, Mengjing Li, Ke Xu, Tongtong Li, Yongzhi Cao, Yue Lv, Gang Lu, Hongbin Liu, Tao Huang
Cells. 2023 Aug; 12(16): 2091. Published online 2023 Aug 18. doi: 10.3390/cells12162091
PMCID:
PMC10453820
AbstractArticlePDF–8.9M
7.
Thymidine phosphorylase facilitates retinoic acid inducible gene-I induced endothelial dysfunction
Adrian Baris, Eugenia Fraile-Bethencourt, Jaiden Eubanks, Sokchea Khou, Sudarshan Anand
Cell Death Dis. 2023 Apr; 14(4): 294. Published online 2023 Apr 26. doi: 10.1038/s41419-023-05821-0
PMCID:
PMC10131517
AbstractArticlePDF–2.4M
8.
Increased levels of endogenous retroviruses trigger fibroinflammation and play a role in kidney disease development
Poonam Dhillon, Kelly Ann Mulholland, Hailong Hu, Jihwan Park, Xin Sheng, Amin Abedini, Hongbo Liu, Allison Vassalotti, Junnan Wu, Katalin Susztak
Nat Commun. 2023; 14: 559. Published online 2023 Feb 2. doi: 10.1038/s41467-023-36212-w
PMCID:
PMC9895454
AbstractArticlePDF–13M
9.
Mutant RIG-I enhances cancer-related inflammation through activation of circRIG-I signaling
Jia Song, Wei Zhao, Xin Zhang, Wenyu Tian, Xuyang Zhao, Liang Ma, Yongtong Cao, Yuxin Yin, Xuehui Zhang, Xuliang Deng, Dan Lu
Nat Commun. 2022; 13: 7096. Published online 2022 Nov 19. doi: 10.1038/s41467-022-34885-3
PMCID:
PMC9675819
AbstractArticlePDF–9.9M
10.
JMJD4-demethylated RIG-I prevents hepatic steatosis and carcinogenesis
Zhenyang Li, Ye Zhou, Kaiwei Jia, Yingyun Yang, Liyuan Zhang, Suyuan Wang, Yue Dong, Mu Wang, Yunhui Li, Shan Lu, Wannian Zhang, Luxin Zhang, Yiwen Fan, Dingji Zhang, Nan Li, Yizhi Yu, Xuetao Cao, Jin Hou
J Hematol Oncol. 2022; 15: 161. Published online 2022 Nov 4. doi: 10.1186/s13045-022-01381-6
PMCID:
PMC9636772
AbstractArticlePDF–12M
11.
RIG-I acts as a tumor suppressor in melanoma via regulating the activation of the MKK/p38MAPK signaling pathway
Rui Guo, Shun-Yuan Lu, Jin-Xia Ma, Qian-Lan Wang, Lu Zhang, Ling-Yun Tang, Yan Shen, Chun-Ling Shen, Jin-Jin Wang, Li-Ming Lu, Zhu-Gang Wang, Hong-Xin Zhang
Hum Cell. 2022; 35(4): 1071–1083. Published online 2022 Apr 13. doi: 10.1007/s13577-022-00698-1
PMCID:
PMC9226095
AbstractArticlePDF–6.0M
12.
Involvement of RIG-I Pathway in Neurotropic Virus-Induced Acute Flaccid Paralysis and Subsequent Spinal Motor Neuron Death
Meenakshi Bhaskar, Sriparna Mukherjee, Anirban Basu
mBio. 2021 Nov-Dec; 12(6): e02712-21. Published online 2021 Nov 16. doi: 10.1128/mBio.02712-21
PMCID:
PMC8593677
AbstractArticlePDF–6.0M
13.
Modulation of SF3B1 in the pre-mRNA spliceosome induces a RIG-I-dependent type I IFN response
Aaron Y. Chang, Yu Jerry Zhou, Sharanya Iyengar, Piotr W. Pobiarzyn, Pavel Tishchenko, Kesha M. Shah, Heather Wheeler, Yue-Ming Wang, Paula M. Loria, Frank Loganzo, Seng-Ryong Woo
J Biol Chem. 2021 Nov; 297(5): 101277. Published online 2021 Oct 5. doi: 10.1016/j.jbc.2021.101277
PMCID:
PMC8559577
AbstractArticlePDF–2.4M
14.
Klotho deficiency intensifies hypoxia-induced expression of IFN-α/β through upregulation of RIG-I in kidneys
Asako Urabe, Shigehiro Doi, Ayumu Nakashima, Takeshi Ike, Kenichi Morii, Kensuke Sasaki, Toshiki Doi, Koji Arihiro, Takao Masaki
PLoS One. 2021; 16(10): e0258856. Published online 2021 Oct 21. doi: 10.1371/journal.pone.0258856
PMCID:
PMC8530307
AbstractArticlePDF–2.1M
15.
Riok3 inhibits the antiviral immune response by facilitating TRIM40-mediated RIG-I and MDA5 degradation
Yong Shen, Kejun Tang, Dongdong Chen, Mengying Hong, Fangfang Sun, SaiSai Wang, Yuehai Ke, Tingting Wu, Ren Sun, Jing Qian, Yushen Du
Cell Rep. Author manuscript; available in PMC 2021 Aug 14.
Published in final edited form as: Cell Rep. 2021 Jun 22; 35(12): 109272. doi: 10.1016/j.celrep.2021.109272
PMCID:
PMC8363743
AbstractArticlePDF–3.2M
16.
FIP200 restricts RNA virus infection by facilitating RIG-I activation
Lingyan Wang, Kun Song, Wenzhuo Hao, Yakun Wu, Girish Patil, Fang Hua, Yiwen Sun, Chaoqun Huang, Jerry Ritchey, Clinton Jones, Lin Liu, Jun-Lin Guan, Shitao Li
Commun Biol. 2021; 4: 921. Published online 2021 Jul 29. doi: 10.1038/s42003-021-02450-1
PMCID:
PMC8322336
AbstractArticlePDF–3.3M
17.
RDUR, a lncRNA, Promotes Innate Antiviral Responses and Provides Feedback Control of NF-κB Activation
Yuhai Chen, Jiayue Hu, Shasha Liu, Biao Chen, Meng Xiao, Yingying Li, Yuan Liao, Kul Raj Rai, Zhonghui Zhao, Jing Ouyang, Qidong Pan, Lianfeng Zhang, Shile Huang, Ji-Long Chen
Front Immunol. 2021; 12: 672165. Published online 2021 May 14. doi: 10.3389/fimmu.2021.672165
PMCID:
PMC8160526
AbstractArticlePDF–4.2M
18.
The herpesvirus accessory protein γ134.5 facilitates viral replication by disabling mitochondrial translocation of RIG-I
Xing Liu, Yijie Ma, Kathleen Voss, Michiel van Gent, Ying Kai Chan, Michaela U. Gack, Michael Gale, Jr, Bin He
PLoS Pathog. 2021 Mar; 17(3): e1009446. Published online 2021 Mar 26. doi: 10.1371/journal.ppat.1009446
PMCID:
PMC7996975
AbstractArticlePDF–2.3M
19.
STING controls nociception via type-I interferon signaling in sensory neurons
Christopher R. Donnelly, Changyu Jiang, Amanda S. Andriessen, Kaiyuan Wang, Zilong Wang, Huiping Ding, Junli Zhao, Xin Luo, Michael S. Lee, Yu L. Lei, William Maixner, Mei-Chuan Ko, Ru-Rong Ji
Nature. Author manuscript; available in PMC 2021 Mar 19.
Published in final edited form as: Nature. 2021 Mar; 591(7849): 275–280. Published online 2021 Jan 13. doi: 10.1038/s41586-020-03151-1
PMCID:
PMC7977781
AbstractArticlePDF–6.9M
20.
Opposite actions of two dsRNA-binding proteins PACT and TRBP on RIG-I mediated signaling
Lauren S. Vaughn, Evelyn Chukwurah, Rekha C Patel
Biochem J. Author manuscript; available in PMC 2022 Feb 12.
Published in final edited form as: Biochem J. 2021 Feb 12; 478(3): 493–510. doi: 10.1042/BCJ20200987
PMCID:
PMC7919947
AbstractArticlePDF–1.6M

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