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Select item 109176601.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 89836542.

Lipid phosphate phosphatase 3 in smooth muscle cells regulates angiotensin II-induced abdominal aortic aneurysm formation

Patrick M. Van Hoose, Liping Yang, Maria Kraemer, Margo Ubele, Andrew J. Morris, Susan S. Smyth

Sci Rep. 2022; 12: 5664. Published online 2022 Apr 5. doi: 10.1038/s41598-022-08422-7

PMCID:: PMC8983654

Abstract Article PDF–4.2M

Select item 77347433.

Altered cleavage plane orientation with increased genomic aneuploidy produced by receptor-mediated lysophosphatidic acid (LPA) signaling in mouse cerebral cortical neural progenitor cells

Whitney S. McDonald, Kyoko Miyamoto, Richard Rivera, Grace Kennedy, Beatriz S. V. Almeida, Marcy A. Kingsbury, Jerold Chun

Mol Brain. 2020; 13: 169. Published online 2020 Dec 14. doi: 10.1186/s13041-020-00709-y

PMCID:: PMC7734743

Abstract Article PDF–2.1M

Select item 68126324.

The coronary artery disease risk-associated Plpp3 gene and its product lipid phosphate phosphatase 3 regulate experimental atherosclerosis

Paul A. Mueller, Liping Yang, Margo Ubele, Guogen Mao, Jason Brandon, Julia Vandra, Timothy C. Nichols, Diana Escalante-Alcalde, Andrew J. Morris, Susan S. Smyth

Arterioscler Thromb Vasc Biol. Author manuscript; available in PMC 2020 Nov 1.

Published in final edited form as: Arterioscler Thromb Vasc Biol. 2019 Nov; 39(11): 2261–2272. Published online 2019 Sep 19. doi: 10.1161/ATVBAHA.119.313056

PMCID:: PMC6812632

Abstract Article PDF–1.0M

Select item 67852485.

LPA_1/3 overactivation induces neonatal posthemorrhagic hydrocephalus through ependymal loss and ciliary dysfunction

Nicole C. Lummis, Paloma Sánchez-Pavón, Grace Kennedy, Aaron J. Frantz, Yasuyuki Kihara, Victoria A. Blaho, Jerold Chun

Sci Adv. 2019 Oct; 5(10): eaax2011. Published online 2019 Oct 9. doi: 10.1126/sciadv.aax2011

PMCID:: PMC6785248

Abstract Article PDF–9.3M

Select item 67632316.

Lysophosphatidic acid–induced YAP/TAZ activation promotes developmental angiogenesis by repressing Notch ligand Dll4

Daisuke Yasuda, Daiki Kobayashi, Noriyuki Akahoshi, Takayo Ohto-Nakanishi, Kazuaki Yoshioka, Yoh Takuwa, Seiya Mizuno, Satoru Takahashi, Satoshi Ishii

J Clin Invest. 2019 Oct 1; 129(10): 4332–4349. Published online 2019 Sep 9. doi: 10.1172/JCI121955

PMCID:: PMC6763231

Abstract Article PDF–21M

Select item 65939767.

LPA₁, LPA₂, LPA₄, and LPA₆ receptor expression during mouse brain development

Olga Suckau, Isabel Gross, Sandra Schrötter, Fan Yang, Jiankai Luo, Andreas Wree, Jerold Chun, David Baska, Jan Baumgart, Kuniyuki Kano, Junken Aoki, Anja U. Bräuer

Dev Dyn. 2019 May; 248(5): 375–395. Published online 2019 Mar 27. doi: 10.1002/dvdy.23

PMCID:: PMC6593976

Abstract Article PDF–11M

Select item 64951748.

LPA receptor 4 deficiency attenuates experimental atherosclerosis

Liping Yang, Maria Kraemer, Xianjun Frank Fang, Peggi M. Angel, Richard R. Drake, Andrew J. Morris, Susan S. Smyth

J Lipid Res. 2019 May; 60(5): 972–980. Published online 2019 Feb 22. doi: 10.1194/jlr.M091066

PMCID:: PMC6495174

Abstract Article PDF–1.1M

Select item 63899839.

Molecular mechanism of lysophosphatidic acid-induced hypertensive response

Kuniyuki Kano, Hirotaka Matsumoto, Asuka Inoue, Hiroshi Yukiura, Motomu Kanai, Jerold Chun, Satoshi Ishii, Takao Shimizu, Junken Aoki

Sci Rep. 2019; 9: 2662. Published online 2019 Feb 25. doi: 10.1038/s41598-019-39041-4

PMCID:: PMC6389983

Abstract Article PDF–2.2M

Select item 612457610.

Mammalian embryo comparison identifies novel pluripotency genes associated with the naïve or primed state

Andreia S. Bernardo, Alice Jouneau, Hendrik Marks, Philip Kensche, Julianna Kobolak, Kristine Freude, Vanessa Hall, Anita Feher, Zsuzsanna Polgar, Chiara Sartori, Istvan Bock, Claire Louet, Tiago Faial, Hindrik H. D. Kerstens, Camille Bouissou, Gregory Parsonage, Kaveh Mashayekhi, James C. Smith, Giovanna Lazzari, Poul Hyttel, Hendrik G. Stunnenberg, Martijn Huynen, Roger A. Pedersen, Andras Dinnyes

Biol Open. 2018 Aug 15; 7(8): bio033282. Published online 2018 Jul 19. doi: 10.1242/bio.033282

PMCID:: PMC6124576

Abstract Article PDF–8.1M

Select item 488521611.

Lysophosphatidic acid receptors LPA₄ and LPA₆ differentially promote lymphocyte transmigration across high endothelial venules in lymph nodes

Erina Hata, Naoko Sasaki, Akira Takeda, Kazuo Tohya, Eiji Umemoto, Noriyuki Akahoshi, Satoshi Ishii, Kana Bando, Takaya Abe, Kuniyuki Kano, Junken Aoki, Haruko Hayasaka, Masayuki Miyasaka

Int Immunol. 2016 Jun; 28(6): 283–292. Published online 2015 Dec 29. doi: 10.1093/intimm/dxv072

PMCID:: PMC4885216

Abstract Article PDF–29M

Select item 447368712.

The lysophosphatidic acid receptor LPA₄ regulates hematopoiesis-supporting activity of bone marrow stromal cells

Hidemitsu Igarashi, Noriyuki Akahoshi, Takayo Ohto-Nakanishi, Daisuke Yasuda, Satoshi Ishii

Sci Rep. 2015; 5: 11410. Published online 2015 Jun 19. doi: 10.1038/srep11410

PMCID:: PMC4473687

Abstract Article PDF–1.4M

Select item 412805813.

Lysophospholipid receptor nomenclature review: IUPHAR Review 8

Yasuyuki Kihara, Michael Maceyka, Sarah Spiegel, Jerold Chun

Br J Pharmacol. 2014 Aug; 171(15): 3575–3594. Published online 2014 Jul 12. doi: 10.1111/bph.12678

PMCID:: PMC4128058

Abstract Article PDF–1.2M

Select item 396495514.

The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data

Gautier Koscielny, Gagarine Yaikhom, Vivek Iyer, Terrence F. Meehan, Hugh Morgan, Julian Atienza-Herrero, Andrew Blake, Chao-Kung Chen, Richard Easty, Armida Di Fenza, Tanja Fiegel, Mark Grifiths, Alan Horne, Natasha A. Karp, Natalja Kurbatova, Jeremy C. Mason, Peter Matthews, Darren J. Oakley, Asfand Qazi, Jack Regnart, Ahmad Retha, Luis A. Santos, Duncan J. Sneddon, Jonathan Warren, Henrik Westerberg, Robert J. Wilson, David G. Melvin, Damian Smedley, Steve D. M. Brown, Paul Flicek, William C. Skarnes, Ann-Marie Mallon, Helen Parkinson

Nucleic Acids Res. 2014 Jan 1; 42(Database issue): D802–D809. Published online 2013 Nov 3. doi: 10.1093/nar/gkt977

PMCID:: PMC3964955

Abstract Article PDF–5.7M

Select item 317805915.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 302253416.

A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo

Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio

PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582

PMCID:: PMC3022534

Abstract Article PDF–3.8M

Select item 293264017.

Diversity of Lysophosphatidic Acid Receptor-Mediated Intracellular Calcium Signaling in Early Cortical Neurogenesis

Adrienne E. Dubin, Deron R. Herr, Jerold Chun

J Neurosci. 2010 May 26; 30(21): 7300–7309. doi: 10.1523/JNEUROSCI.6151-09.2010

PMCID:: PMC2932640

Abstract Article PDF–1.5M

Select item 259265618.

Role of LPA₄/p2y9/GPR23 in Negative Regulation of Cell Motility

Zendra Lee, Ching-Ting Cheng, Helen Zhang, Mark A. Subler, Jinhua Wu, Abir Mukherjee, Jolene J. Windle, Ching-Kang Chen, Xianjun Fang

Mol Biol Cell. 2008 Dec; 19(12): 5435–5445. doi: 10.1091/mbc.E08-03-0316

PMCID:: PMC2592656

Abstract Article PDF–569K

Select item 256207719.

Runx2 Regulates G Protein-coupled Signaling Pathways to Control Growth of Osteoblast Progenitors

Nadiya M. Teplyuk, Mario Galindo, Viktor I. Teplyuk, Jitesh Pratap, Daniel W. Young, David Lapointe, Amjad Javed, Janet L. Stein, Jane B. Lian, Gary S. Stein, Andre J. van Wijnen

J Biol Chem. 2008 Oct 10; 283(41): 27585–27597. doi: 10.1074/jbc.M802453200

PMCID:: PMC2562077

Abstract Article PDF–842K

Select item 255627020.

Large-scale gene trapping in C57BL/6N mouse embryonic stem cells

Gwenn M. Hansen, Diane C. Markesich, Michael B. Burnett, Qichao Zhu, Karen M. Dionne, Lizabeth J. Richter, Richard H. Finnell, Arthur T. Sands, Brian P. Zambrowicz, Alejandro Abuin

Genome Res. 2008 Oct; 18(10): 1670–1679. doi: 10.1101/gr.078352.108

PMCID:: PMC2556270

Abstract Article PDF–493K

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