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Items: 1 to 20 of 33

1.
Heart rate reduction after genetic ablation of L-type Cav1.3 channels induces cardioprotection against ischemia-reperfusion injury
Viviana Delgado-Betancourt, Kroekkiat Chinda, Pietro Mesirca, Christian Barrère, Aurélie Covinhes, Laura Gallot, Anne Vincent, Isabelle Bidaud, Sarawut Kumphune, Joël Nargeot, Christophe Piot, Kevin Wickman, Matteo Elia Mangoni, Stéphanie Barrère-Lemaire
Front Cardiovasc Med. 2023; 10: 1134503. Published online 2023 Aug 1. doi: 10.3389/fcvm.2023.1134503
PMCID:
PMC10429177
AbstractArticlePDF–4.6M
2.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
3.
Genetic Ablation of G Protein-Gated Inwardly Rectifying K+ Channels Prevents Training-Induced Sinus Bradycardia
Isabelle Bidaud, Alicia D’Souza, Gabriella Forte, Eleonora Torre, Denis Greuet, Steeve Thirard, Cali Anderson, Antony Chung You Chong, Angelo G. Torrente, Julien Roussel, Kevin Wickman, Mark R. Boyett, Matteo E. Mangoni, Pietro Mesirca
Front Physiol. 2020; 11: 519382. Published online 2021 Jan 20. doi: 10.3389/fphys.2020.519382
PMCID:
PMC7857143
AbstractArticlePDF–5.1M
4.
GPCR-dependent biasing of GIRK channel signaling dynamics by RGS6 in mouse sinoatrial nodal cells
Allison Anderson, Ikuo Masuho, Ezequiel Marron Fernandez de Velasco, Atsushi Nakano, Lutz Birnbaumer, Kirill A. Martemyanov, Kevin Wickman
Proc Natl Acad Sci U S A. 2020 Jun 23; 117(25): 14522–14531. Published online 2020 Jun 8. doi: 10.1073/pnas.2001270117
PMCID:
PMC7322085
AbstractArticlePDF–1.6M
5.
Brain Localization and Behavioral Impact of the G-Protein-Gated K+ Channel Subunit GIRK4
Kevin Wickman, Christine Karschin, Andreas Karschin, Marina R. Picciotto, David E. Clapham
J Neurosci. 2000 Aug 1; 20(15): 5608–5615. doi: 10.1523/JNEUROSCI.20-15-05608.2000
PMCID:
PMC6772558
AbstractArticlePDF–867K
6.
Development of a New Genetic Model for Absence Epilepsy: Spike-Wave Seizures in C3H/He and Backcross Mice
Wayne N. Frankel, Barbara Beyer, Christina R. Maxwell, Stephanie Pretel, Verity A. Letts, Steven J. Siegel
J Neurosci. 2005 Mar 30; 25(13): 3452–3458. doi: 10.1523/JNEUROSCI.0231-05.2005
PMCID:
PMC6724901
AbstractArticlePDF–563K
7.
Targeted disruption of the Kcnj5 gene in the female mouse lowers aldosterone levels
Iris Hardege, Lu Long, Raya Al Maskari, Nicola Figg, Kevin M. O’Shaughnessy
Clin Sci (Lond) 2018 Jan 16; 132(1): 145–156. Prepublished online 2017 Dec 8. Published online 2018 Jan 16. doi: 10.1042/CS20171285
PMCID:
PMC6365593
AbstractArticlePDF–1.1M
8.
Atrial GIRK Channels Mediate the Effects of Vagus Nerve Stimulation on Heart Rate Dynamics and Arrhythmogenesis
Steven W. Lee, Allison Anderson, Pilar A. Guzman, Atsushi Nakano, Elena G. Tolkacheva, Kevin Wickman
Front Physiol. 2018; 9: 943. Published online 2018 Jul 19. doi: 10.3389/fphys.2018.00943
PMCID:
PMC6060443
AbstractArticlePDF–2.4M
9.
The influences of the M2R-GIRK4-RGS6 dependent parasympathetic pathway on electrophysiological properties of the mouse heart
Kanchan Kulkarni, Xueyi Xie, Ezequiel Marron Fernandez de Velasco, Allison Anderson, Kirill A. Martemyanov, Kevin Wickman, Elena G. Tolkacheva
PLoS One. 2018; 13(4): e0193798. Published online 2018 Apr 18. doi: 10.1371/journal.pone.0193798
Correction in:
PLoS One. 2018; 13(7): e0200553.
PMCID:
PMC5905881
AbstractArticlePDF–4.0M
10.
Expression and relevance of the G protein-gated K+ channel in the mouse ventricle
Allison Anderson, Kanchan Kulkarni, Ezequiel Marron Fernandez de Velasco, Nicholas Carlblom, Zhilian Xia, Atsushi Nakano, Kirill A. Martemyanov, Elena G. Tolkacheva, Kevin Wickman
Sci Rep. 2018; 8: 1192. Published online 2018 Jan 19. doi: 10.1038/s41598-018-19719-x
PMCID:
PMC5775354
AbstractArticlePDF–6.3M
11.
G protein-gated IKACh channels as therapeutic targets for treatment of sick sinus syndrome and heart block
Pietro Mesirca, Isabelle Bidaud, François Briec, Stéphane Evain, Angelo G. Torrente, Khai Le Quang, Anne-Laure Leoni, Matthias Baudot, Laurine Marger, Antony Chung You Chong, Joël Nargeot, Joerg Striessnig, Kevin Wickman, Flavien Charpentier, Matteo E. Mangoni
Proc Natl Acad Sci U S A. 2016 Feb 16; 113(7): E932–E941. Published online 2016 Feb 1. doi: 10.1073/pnas.1517181113
PMCID:
PMC4763776
AbstractArticlePDF–2.3M
12.
LKB1 deletion causes early changes in atrial channel expression and electrophysiology prior to atrial fibrillation
Grace E. Kim, Jenna L. Ross, Chaoqin Xie, Kevin N. Su, Vlad G. Zaha, Xiaohong Wu, Monica Palmeri, Mohammed Ashraf, Joseph G. Akar, Kerry S. Russell, Fadi G. Akar, Lawrence H. Young
Cardiovasc Res. 2015 Oct 1; 108(1): 197–208. Published online 2015 Sep 7. doi: 10.1093/cvr/cvv212
PMCID:
PMC4571838
AbstractArticlePDF–1.3M
13.
Cardiac arrhythmia induced by genetic silencing of “funny” (f) channels is rescued by GIRK4 inactivation
Pietro Mesirca, Jacqueline Alig, Angelo G. Torrente, Jana Christina Müller, Laurine Marger, Anne Rollin, Claire Marquilly, Anne Vincent, Stefan Dubel, Isabelle Bidaud, Anne Fernandez, Anika Seniuk, Birgit Engeland, Jasmin Singh, Lucile Miquerol, Heimo Ehmke, Thomas Eschenhagen, Joel Nargeot, Kevin Wickman, Dirk Isbrandt, Matteo E. Mangoni
Nat Commun. Author manuscript; available in PMC 2015 Feb 21.
Published in final edited form as: Nat Commun. 2014; 5: 4664. Published online 2014 Aug 21. doi: 10.1038/ncomms5664
PMCID:
PMC4207211
AbstractArticlePDF–3.4M
14.
G-protein-coupled inward rectifier potassium current contributes to ventricular repolarization
Bo Liang, Jakob D. Nissen, Morten Laursen, Xiaodong Wang, Lasse Skibsbye, Matthew C. Hearing, Martin N. Andersen, Hanne B. Rasmussen, Kevin Wickman, Morten Grunnet, Søren-Peter Olesen, Thomas Jespersen
Cardiovasc Res. 2014 Jan 1; 101(1): 175–184. Published online 2013 Oct 22. doi: 10.1093/cvr/cvt240
PMCID:
PMC3868351
AbstractArticlePDF–1.9M
15.
Essential Role of the m2R-RGS6-IKACh Pathway in Controlling Intrinsic Heart Rate Variability
Ekaterina Posokhova, David Ng, Aaisha Opel, Ikuo Masuho, Andrew Tinker, Leslie G. Biesecker, Kevin Wickman, Kirill A. Martemyanov
PLoS One. 2013; 8(10): e76973. Published online 2013 Oct 29. doi: 10.1371/journal.pone.0076973
PMCID:
PMC3812209
AbstractArticlePDF–1.0M
16.
The G-protein–gated K+ channel, IKACh, is required for regulation of pacemaker activity and recovery of resting heart rate after sympathetic stimulation
Pietro Mesirca, Laurine Marger, Futoshi Toyoda, Riccardo Rizzetto, Matthieu Audoubert, Stefan Dubel, Angelo G. Torrente, Mattia L. DiFrancesco, Jana Christina Muller, Anne-Laure Leoni, Brigitte Couette, Joël Nargeot, David E. Clapham, Kevin Wickman, Matteo E. Mangoni
J Gen Physiol. 2013 Aug; 142(2): 113–126. doi: 10.1085/jgp.201310996
PMCID:
PMC3727310
AbstractArticlePDF–2.1M
17.
Cardiac specific ATP-sensitive K+ channel (KATP) overexpression results in embryonic lethality
Amir Toib, Hai Xia Zhang, Thomas J. Broekelmann, Krzysztof L. Hyrc, Qiusha Guo, Feng Chen, Maria S. Remedi, Colin G. Nichols
J Mol Cell Cardiol. Author manuscript; available in PMC 2013 Sep 1.
Published in final edited form as: J Mol Cell Cardiol. 2012 Sep; 53(3): 437–445. Published online 2012 Jul 13. doi: 10.1016/j.yjmcc.2012.07.001
PMCID:
PMC3423334
AbstractArticlePDF–2.4M
18.
Dystrophin Is Required for the Normal Function of the Cardio-Protective KATP Channel in Cardiomyocytes
Laura Graciotti, Jodi Becker, Anna Luisa Granata, Antonio Domenico Procopio, Lino Tessarollo, Gianluca Fulgenzi
PLoS One. 2011; 6(10): e27034. Published online 2011 Oct 31. doi: 10.1371/journal.pone.0027034
PMCID:
PMC3205025
AbstractArticlePDF–596K
19.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
20.
A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo
Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio
PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582
PMCID:
PMC3022534
AbstractArticlePDF–3.8M

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