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Items: 1 to 20 of 30

1.
Overexpression of Nfe2l1 increases proteasome activity and delays vision loss in a preclinical model of human blindness
Yixiao Wang, Aaron Snell, Frank M. Dyka, Elizabeth R. Colvin, Cristhian Ildefonso, John D. Ash, Ekaterina S. Lobanova
Sci Adv. 2023 Jul; 9(28): eadd5479. Published online 2023 Jul 14. doi: 10.1126/sciadv.add5479
PMCID:
PMC10348684
AbstractArticlePDF–2.1M
2.
Regulation of rod photoreceptor function by farnesylated G-protein γ-subunits
Alexander V. Kolesnikov, Elena Lobysheva, Jaya P. Gnana-Prakasam, Vladimir J. Kefalov, Oleg G. Kisselev
PLoS One. 2022; 17(8): e0272506. Published online 2022 Aug 8. doi: 10.1371/journal.pone.0272506
PMCID:
PMC9359561
AbstractArticlePDF–3.6M
3.
Disabling the Gβγ-SNARE interaction disrupts GPCR-mediated presynaptic inhibition, leading to physiological and behavioral phenotypes
Zack Zurawski, Analisa D. Thompson Gray, Lillian J. Brady, Brian Page, Emily Church, Nicholas A. Harris, Michael R. Dohn, Yun Young Yim, Karren Hyde, Douglas P. Mortlock, Carrie K. Jones, Danny G. Winder, Simon Alford, Heidi E. Hamm
Sci Signal. Author manuscript; available in PMC 2020 Dec 24.
Published in final edited form as: Sci Signal. 2019 Feb 19; 12(569): eaat8595. Published online 2019 Feb 19. doi: 10.1126/scisignal.aat8595
PMCID:
PMC7758873
AbstractArticlePDF–1.8M
4.
Mouse Models of Inherited Retinal Degeneration with Photoreceptor Cell Loss
Gayle B. Collin, Navdeep Gogna, Bo Chang, Nattaya Damkham, Jai Pinkney, Lillian F. Hyde, Lisa Stone, Jürgen K. Naggert, Patsy M. Nishina, Mark P. Krebs
Cells. 2020 Apr; 9(4): 931. Published online 2020 Apr 10. doi: 10.3390/cells9040931
PMCID:
PMC7227028
AbstractArticlePDF–5.4M
5.
Probing Proteostatic Stress in Degenerating Photoreceptors Using Two Complementary In Vivo Reporters of Proteasomal Activity
Paige M. Dexter, Ekaterina S. Lobanova, Stella Finkelstein, Vadim Y. Arshavsky
eNeuro. 2020 Jan-Feb; 7(1): ENEURO.0428-19.2019. Prepublished online 2019 Dec 11. Published online 2020 Jan 2. doi: 10.1523/ENEURO.0428-19.2019
PMCID:
PMC6948925
AbstractArticlePDF–1.3M
6.
Cul3‐Klhl18 ubiquitin ligase modulates rod transducin translocation during light‐dark adaptation
Taro Chaya, Ryotaro Tsutsumi, Leah Rie Varner, Yamato Maeda, Satoyo Yoshida, Takahisa Furukawa
EMBO J. 2019 Dec 2; 38(23): e101409. Published online 2019 Nov 7. doi: 10.15252/embj.2018101409
PMCID:
PMC6885741
AbstractArticlePDF–5.2M
7.
Archaeal Unfoldase Counteracts Protein Misfolding Retinopathy in Mice
Celine Brooks, Aaron Snoberger, Marycharmain Belcastro, Joseph Murphy, Oleg G. Kisselev, David M. Smith, Maxim Sokolov
J Neurosci. 2018 Aug 15; 38(33): 7248–7254. doi: 10.1523/JNEUROSCI.0905-18.2018
PMCID:
PMC6096037
AbstractArticlePDF–2.5M
8.
Transducin β-Subunit Can Interact with Multiple G-Protein γ-Subunits to Enable Light Detection by Rod Photoreceptors
Paige M. Dexter, Ekaterina S. Lobanova, Stella Finkelstein, William J. Spencer, Nikolai P. Skiba, Vadim Y. Arshavsky
eNeuro. 2018 May-Jun; 5(3): ENEURO.0144-18.2018. Prepublished online 2018 May 17. Published online 2018 Jun 11. doi: 10.1523/ENEURO.0144-18.2018
PMCID:
PMC6001135
AbstractArticlePDF–1.4M
9.
Farnesylation of the Transducin G Protein Gamma Subunit Is a Prerequisite for Its Ciliary Targeting in Rod Photoreceptors
Celine Brooks, Joseph Murphy, Marycharmain Belcastro, Daniel Heller, Saravanan Kolandaivelu, Oleg Kisselev, Maxim Sokolov
Front Mol Neurosci. 2018; 11: 16. Published online 2018 Jan 23. doi: 10.3389/fnmol.2018.00016
PMCID:
PMC5787109
AbstractArticlePDF–2.6M
10.
IGF-1 activates a cilium-localized non-canonical Gβγ signaling pathway that regulates cell cycle progression
Celine Yeh, Aiqun Li, Jen-Zen Chuang, Masaki Saito, Alfredo Cáceres, Ching-Hwa Sung
Dev Cell. Author manuscript; available in PMC 2014 Aug 26.
Published in final edited form as: Dev Cell. 2013 Aug 26; 26(4): 358–368. Published online 2013 Aug 15. doi: 10.1016/j.devcel.2013.07.014
PMCID:
PMC3790638
AbstractArticlePDF–5.1M
11.
Proteasome overload is a common stress factor in multiple forms of inherited retinal degeneration
Ekaterina S. Lobanova, Stella Finkelstein, Nikolai P. Skiba, Vadim Y. Arshavsky
Proc Natl Acad Sci U S A. 2013 Jun 11; 110(24): 9986–9991. Published online 2013 May 28. doi: 10.1073/pnas.1305521110
PMCID:
PMC3683722
AbstractArticlePDF–918K
12.
Functional Comparison of Rod and Cone Gαt on the Regulation of Light Sensitivity
Wen Mao, K. J. Miyagishima, Yun Yao, Brian Soreghan, Alapakkam P. Sampath, Jeannie Chen
J Biol Chem. 2013 Feb 22; 288(8): 5257–5267. Published online 2013 Jan 3. doi: 10.1074/jbc.M112.430058
PMCID:
PMC3581426
AbstractArticlePDF–1.7M
13.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M
14.
G-protein–mediated inhibition of the Trp channel TRPM1 requires the Gβγ dimer
Yin Shen, Melissa Ann F. Rampino, Reed C. Carroll, Scott Nawy
Proc Natl Acad Sci U S A. 2012 May 29; 109(22): 8752–8757. Published online 2012 May 14. doi: 10.1073/pnas.1117433109
PMCID:
PMC3365217
AbstractArticlePDF–466K
15.
Signaling States of Rhodopsin in Rod Disk Membranes Lacking Transducin βγ-Complex
Elena Lomonosova, Alexander V. Kolesnikov, Vladimir J. Kefalov, Oleg G. Kisselev
Invest Ophthalmol Vis Sci. 2012 Mar; 53(3): 1225–1233. Published online 2012 Mar 9. doi: 10.1167/iovs.11-9350
PMCID:
PMC3339904
AbstractArticlePDF–1.3M
16.
The WD40 Repeat Protein WDR26 Binds Gβγ and Promotes Gβγ-dependent Signal Transduction and Leukocyte Migration
Zhizeng Sun, Xiaoyun Tang, Fang Lin, Songhai Chen
J Biol Chem. 2011 Dec 23; 286(51): 43902–43912. Published online 2011 Nov 7. doi: 10.1074/jbc.M111.301382
PMCID:
PMC3243526
AbstractArticlePDF–1.9M
17.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
18.
G-Protein βγ-Complex Is Crucial for Efficient Signal Amplification in Vision
Alexander V. Kolesnikov, Loryn Rikimaru, Anne K. Hennig, Peter D. Lukasiewicz, Steven J. Fliesler, Victor I. Govardovskii, Vladimir J. Kefalov, Oleg G. Kisselev
J Neurosci. 2011 Jun 1; 31(22): 8067–8077. doi: 10.1523/JNEUROSCI.0174-11.2011
PMCID:
PMC3118088
AbstractArticlePDF–1.5M
19.
Phosducin Regulates Transmission at thePhotoreceptor-to-ON-Bipolar Cell Synapse
Rolf Herrmann, Ekaterina S. Lobanova, Timothy Hammond, Christopher Kessler, Marie E. Burns, Laura J. Frishman, Vadim Y. Arshavsky
J Neurosci. 2010 Mar 3; 30(9): 3239–3253. doi: 10.1523/JNEUROSCI.4775-09.2010
PMCID:
PMC2927985
AbstractArticlePDF–8.2M
20.
Farnesylation of Retinal Transducin Underlies Its Translocation during Light Adaptation
Hidetoshi Kassai, Atsu Aiba, Kazuki Nakao, Kenji Nakamura, Motoya Katsuki, Wei-Hong Xiong, King-Wai Yau, Hiroo Imai, Yoshinori Shichida, Yoshinori Satomi, Toshifumi Takao, Toshiyuki Okano, Yoshitaka Fukada
Neuron. Author manuscript; available in PMC 2010 Jun 15.
Published in final edited form as: Neuron. 2005 Aug 18; 47(4): 529–539. doi: 10.1016/j.neuron.2005.07.025
PMCID:
PMC2885908
AbstractArticlePDF–1.6M

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