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Select item 108480491.

Presenilin‐2 knock‐In mice show severe depressive behavior via DVL3 downregulation

Seung Sik Yoo, Dong Won Lee, Hyeon Joo Ham, In Jun Yeo, Ju Young Chang, Jaesuk Yun, Dong Ju Son, Sang‐Bae Han, Jin Tae Hong

CNS Neurosci Ther. 2024 Feb; 30(2): e14370. Published online 2023 Jul 27. doi: 10.1111/cns.14370

PMCID:: PMC10848049

Abstract Article PDF–2.9M

Select item 83132392.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Abstract Article PDF–1.6M

Select item 83012313.

Deletion of the Dishevelled Family of Genes Disrupts Anterior-Posterior Axis Specification and Selectively Prevents Mesoderm Differentiation

Justine Ngo, Masakazu Hashimoto, Hiroshi Hamada, Anthony Wynshaw-Boris

Dev Biol. Author manuscript; available in PMC 2021 Aug 15.

Published in final edited form as: Dev Biol. 2020 Aug 15; 464(2): 161–175. Published online 2020 Jun 21. doi: 10.1016/j.ydbio.2020.05.010

PMCID:: PMC8301231

Abstract Article PDF–2.2M

Select item 76597104.

Wnts regulate planar cell polarity via heterotrimeric G protein and PI3K signaling

Andre Landin Malt, Arielle K. Hogan, Connor D. Smith, Maxwell S. Madani, Xiaowei Lu

J Cell Biol. 2020 Oct 5; 219(10): e201912071. Published online 2020 Aug 17. doi: 10.1083/jcb.201912071

PMCID:: PMC7659710

Abstract Article PDF–5.1M

Select item 76452135.

Malformation of Tear Ducts Underlies the Epiphora and Precocious Eyelid Opening in Prickle 1 Mutant Mice: Genetic Implications for Tear Duct Genesis

Jiali Ru, Dianlei Guo, Jiaying Fan, Jiao Zhang, Rong Ju, Hong Ouyang, Lai Wei, Yizhi Liu, Chunqiao Liu

Invest Ophthalmol Vis Sci. 2020 Nov; 61(13): 6. Published online 2020 Nov 3. doi: 10.1167/iovs.61.13.6

PMCID:: PMC7645213

Abstract Article PDF–35M

Select item 75614806.

Dual regulation of planar polarization by secreted Wnts and Vangl2 in the developing mouse cochlea

Elvis Huarcaya Najarro, Jennifer Huang, Adrian Jacobo, Lee A. Quiruz, Nicolas Grillet, Alan G. Cheng

Development. 2020 Oct 1; 147(19): dev191981. Published online 2020 Oct 5. doi: 10.1242/dev.191981

PMCID:: PMC7561480

Abstract Article

Select item 72251297.

Cleft lip and cleft palate in Esrp1 knockout mice is associated with alterations in epithelial-mesenchymal crosstalk

SungKyoung Lee, Matthew J. Sears, Zijun Zhang, Hong Li, Imad Salhab, Philippe Krebs, Yi Xing, Hyun-Duck Nah, Trevor Williams, Russ P. Carstens

Development. 2020 Nov 1; 147(21): dev187369. Published online 2020 May 4. doi: 10.1242/dev.187369

PMCID:: PMC7225129

Abstract Article

Select item 70359598.

TLR4 induced Wnt3a-Dvl3 restrains the intensity of inflammation and protects against endotoxin-driven organ failure through GSK3β/β-catenin signaling

Dongqiang Yang, ShuJian Li, Xiaoxian Duan, Junling Ren, Shuang Liang, Lan Yakoumatous, Yi Kang, Silvia M. Uriarte, Jia Shuang, Wei Li, Huizhi Wang

Mol Immunol. Author manuscript; available in PMC 2021 Feb 1.

Published in final edited form as: Mol Immunol. 2020 Feb; 118: 153–164. Published online 2019 Dec 26. doi: 10.1016/j.molimm.2019.12.013

PMCID:: PMC7035959

Abstract Article PDF–2.0M

Select item 66023099.

Developmental origins for semilunar valve stenosis identified in mice harboring congenital heart disease-associated GATA4 mutation

Stephanie LaHaye, Uddalak Majumdar, Jun Yasuhara, Sara N. Koenig, Adrianna Matos-Nieves, Rahul Kumar, Vidu Garg

Dis Model Mech. 2019 Jun 1; 12(6): dmm036764. Published online 2019 Jun 24. doi: 10.1242/dmm.036764

PMCID:: PMC6602309

Abstract Article

Select item 605206710.

The potassium channel KCNJ13 is essential for smooth muscle cytoskeletal organization during mouse tracheal tubulogenesis

Wenguang Yin, Hyun-Taek Kim, ShengPeng Wang, Felix Gunawan, Lei Wang, Keishi Kishimoto, Hua Zhong, Dany Roman, Jens Preussner, Stefan Guenther, Viola Graef, Carmen Buettner, Beate Grohmann, Mario Looso, Mitsuru Morimoto, Graeme Mardon, Stefan Offermanns, Didier Y. R. Stainier

Nat Commun. 2018; 9: 2815. Published online 2018 Jul 19. doi: 10.1038/s41467-018-05043-5

PMCID:: PMC6052067

Abstract Article PDF–11M

Select item 585159411.

T-Box transcription factor Tbx20 regulates a genetic program for cranial motor neuron cell body migration

Mi-Ryoung Song, Ryuichi Shirasaki, Chen-Leng Cai, Esmeralda C. Ruiz, Sylvia M. Evans, Soo-Kyung Lee, Samuel L. Pfaff

Development. Author manuscript; available in PMC 2018 Mar 14.

Published in final edited form as: Development. 2006 Dec; 133(24): 4945–4955. doi: 10.1242/dev.02694

PMCID:: PMC5851594

Abstract Article PDF–1.1M

Select item 583370812.

Let-7c inhibits cholangiocarcinoma growth but promotes tumor cell invasion and growth at extrahepatic sites

Yu Xie, Hang Zhang, Xing-Jun Guo, Ye-Chen Feng, Rui-Zhi He, Xu Li, Shuo Yu, Yan Zhao, Ming Shen, Feng Zhu, Xin Wang, Min Wang, Asha Balakrishnan, Michael Ott, Feng Peng, Ren-Yi Qin

Cell Death Dis. 2018 Feb; 9(2): 249. Published online 2018 Feb 14. doi: 10.1038/s41419-018-0286-6

PMCID:: PMC5833708

Abstract Article PDF–5.7M

Select item 461754013.

Global genetic analysis in mice unveils central role for cilia in congenital heart disease

You Li, Nikolai T. Klena, George C Gabriel, Xiaoqin Liu, Andrew J. Kim, Kristi Lemke, Yu Chen, Bishwanath Chatterjee, William Devine, Rama Rao Damerla, Chien-fu Chang, Hisato Yagi, Jovenal T. San Agustin, Mohamed Thahir, Shane Anderton, Caroline Lawhead, Anita Vescovi, Herbert Pratt, Judy Morgan, Leslie Haynes, Cynthia L. Smith, Janan T. Eppig, Laura Reinholdt, Richard Francis, Linda Leatherbury, Madhavi K. Ganapathiraju, Kimimasa Tobita, Gregory J. Pazour, Cecilia W. Lo

Nature. Author manuscript; available in PMC 2015 Nov 28.

Published in final edited form as: Nature. 2015 May 28; 521(7553): 520–524. Published online 2015 Mar 25. doi: 10.1038/nature14269

PMCID:: PMC4617540

Abstract Article PDF–518K

Select item 431955914.

A high resolution spatiotemporal atlas of gene expression of the developing mouse brain

Carol L. Thompson, Lydia Ng, Vilas Menon, Salvador Martinez, Chang-Kyu Lee, Katie Glattfelder, Susan M. Sunkin, Alex Henry, Christopher Lau, Chinh Dang, Raquel Garcia-Lopez, Almudena Martinez-Ferre, Ana Pombero, John L.R. Rubenstein, Wayne B. Wakeman, John Hohmann, Nick Dee, Andrew J. Sodt, Rob Young, Kimberly Smith, Thuc-Nghi Nguyen, Jolene Kidney, Leonard Kuan, Andreas Jeromin, Ajamete Kaykas, Jeremy Miller, Damon Page, Geri Orta, Amy Bernard, Zackery Riley, Simon Smith, Paul Wohnoutka, Mike Hawrylycz, Luis Puelles, Allan R. Jones

Neuron. Author manuscript; available in PMC 2015 Jul 16.

Published in final edited form as: Neuron. 2014 Jul 16; 83(2): 309–323. Published online 2014 Jun 19. doi: 10.1016/j.neuron.2014.05.033

PMCID:: PMC4319559

Abstract Article PDF–3.0M

Select item 416881815.

Atmin mediates kidney morphogenesis by modulating Wnt signaling

Paraskevi Goggolidou, Nazreen F. Hadjirin, Aggie Bak, Eugenia Papakrivopoulou, Helen Hilton, Dominic P. Norris, Charlotte H. Dean

Hum Mol Genet. 2014 Oct 15; 23(20): 5303–5316. Published online 2014 May 22. doi: 10.1093/hmg/ddu246

PMCID:: PMC4168818

Abstract Article PDF–2.6M

Select item 412688216.

Loss of Dishevelleds disrupts planar polarity in ependymal motile cilia and results in hydrocephalus

Shinya Ohata, Jin Nakatani, Vicente Herranz-Pérez, JrGang Cheng, Haim Belinson, Toshiro Inubushi, William D. Snider, Jose Manuel García-Verdugo, Anthony Wynshaw-Boris, Arturo Álvarez-Buylla

Neuron. Author manuscript; available in PMC 2015 Aug 6.

Published in final edited form as: Neuron. 2014 Aug 6; 83(3): 558–571. Published online 2014 Jul 18. doi: 10.1016/j.neuron.2014.06.022

PMCID:: PMC4126882

Abstract Article PDF–1.4M

Select item 410931117.

GSK-3 signaling in developing cortical neurons is essential for radial migration and dendritic orientation

Meghan Morgan-Smith, Yaohong Wu, Xiaoqin Zhu, Julia Pringle, William D Snider

eLife. 2014; 3: e02663. Published online 2014 Jul 29. doi: 10.7554/eLife.02663

PMCID:: PMC4109311

Abstract Article PDF–9.2M

Select item 409429518.

RIPK4 phosphorylates Dishevelled proteins to regulate canonical Wnt signaling

XiaoDong Huang, James C. McGann, Bob Y. Liu, Rami N. Hannoush, Jennie R. Lill, Victoria Pham, Kim Newton, Michael Kakunda, Jinfeng Liu, Christine Yu, Sarah G. Hymowitz, Jo-Anne Hongo, Anthony Wynshaw-Boris, Paul Polakis, Richard M. Harland, Vishva M. Dixit

Science. Author manuscript; available in PMC 2014 Jul 11.

Published in final edited form as: Science. 2013 Mar 22; 339(6126): 1441–1445. Published online 2013 Jan 31. doi: 10.1126/science.1232253

PMCID:: PMC4094295

Abstract Article PDF–930K

Select item 384109719.

Wdpcp, a PCP Protein Required for Ciliogenesis, Regulates Directional Cell Migration and Cell Polarity by Direct Modulation of the Actin Cytoskeleton

Cheng Cui, Bishwanath Chatterjee, Thomas P. Lozito, Zhen Zhang, Richard J. Francis, Hisato Yagi, Lisa M. Swanhart, Subramaniam Sanker, Deanne Francis, Qing Yu, Jovenal T. San Agustin, Chandrakala Puligilla, Tania Chatterjee, Terry Tansey, Xiaoqin Liu, Matthew W. Kelley, Elias T. Spiliotis, Adam V. Kwiatkowski, Rocky Tuan, Gregory J. Pazour, Neil A. Hukriede, Cecilia W. Lo

PLoS Biol. 2013 Nov; 11(11): e1001720. Published online 2013 Nov 26. doi: 10.1371/journal.pbio.1001720

PMCID:: PMC3841097

Abstract Article PDF–7.4M

Select item 370919620.

LRRK2 functions as a Wnt signaling scaffold, bridging cytosolic proteins and membrane-localized LRP6

Daniel C. Berwick, Kirsten Harvey

Hum Mol Genet. 2012 Nov 15; 21(22): 4966–4979. Published online 2012 Aug 16. doi: 10.1093/hmg/dds342

PMCID:: PMC3709196

Abstract Article PDF–762K

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