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Items: 1 to 20 of 35

1.
Impaired OTUD7A-dependent Ankyrin regulation mediates neuronal dysfunction in mouse and human models of the 15q13.3 microdeletion syndrome
Brianna K. Unda, Leon Chalil, Sehyoun Yoon, Savannah Kilpatrick, Courtney Irwin, Sansi Xing, Nadeem Murtaza, Anran Cheng, Chad Brown, Alexandria Afonso, Elizabeth McCready, Gabriel M. Ronen, Jennifer Howe, Aurélie Caye-Eude, Alain Verloes, Brad W. Doble, Laurence Faivre, Antonio Vitobello, Stephen W. Scherer, Yu Lu, Peter Penzes, Karun K. Singh
Mol Psychiatry. 2023; 28(4): 1747–1769. Published online 2023 Jan 6. doi: 10.1038/s41380-022-01937-5
PMCID:
PMC10208958
AbstractArticlePDF–7.0M
2.
Mapping Brain Gene Coexpression in Daytime Transcriptomes Unveils Diurnal Molecular Networks and Deciphers Perturbation Gene Signatures
Nan Wang, Peter Langfelder, Matthew Stricos, Lalini Ramanathan, Jeffrey B. Richman, Raymond Vaca, Mary Plascencia, Xiaofeng Gu, Shasha Zhang, T. Katherine Tamai, Liguo Zhang, Fuying Gao, Koliane Ouk, Xiang Lu, Leonya Ivanov, Tom Vogt, Qing Richard Lu, A. Jennifer Morton, Christopher Colwell, Jeffrey S. Aaronson, Jim Rosinski, Steve Horvath, X. William Yang
Neuron. Author manuscript; available in PMC 2023 Oct 19.
Published in final edited form as: Neuron. 2022 Oct 19; 110(20): 3318–3338.e9. doi: 10.1016/j.neuron.2022.09.028
PMCID:
PMC9665885
AbstractArticlePDF–4.5M
3.
ALS-linked loss of Cyclin-F function affects HSP90
Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends
Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359
PMCID:
PMC9481933
AbstractArticlePDF–3.5M
4.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
5.
Superoxide-induced Type I Collagen Secretion Depends on Prolyl 4-Hydroxylases
Run Shi, Shanshan Gao, Andrew H. Smith, Huan Li, Ming Shao, Jianhui Shangguan, Jie Zhang, Jiang Xu, Jun Ye, Linda M. Graham, Chaoyang Li
Biochem Biophys Res Commun. Author manuscript; available in PMC 2021 Sep 3.
Published in final edited form as: Biochem Biophys Res Commun. 2020 Sep 3; 529(4): 1011–1017. Published online 2020 Jul 30. doi: 10.1016/j.bbrc.2020.07.002
PMCID:
PMC7442856
AbstractArticlePDF–1.3M
6.
Methyltransferase-like 21e inhibits 26S proteasome activity to facilitate hypertrophy of type IIb myofibers
Chao Wang, Bin Zhang, Anna C. Ratliff, Justine Arrington, Jingjuan Chen, Yan Xiong, Feng Yue, Yaohui Nie, Keping Hu, Wen Jin, W. Andy Tao, Christine A. Hrycyna, Xiaobo Sun, Shihuan Kuang
FASEB J. 2019 Aug; 33(8): 9672–9684. Published online 2019 Jun 4. doi: 10.1096/fj.201900582R
PMCID:
PMC6993925
AbstractArticle
7.
Ascorbate inducible N259 glycans on prolyl 4-hydroxylase subunit α1 promote hydroxylation and secretion of type I collagen
Run Shi, Weimin Hu, Yan Zhang, Shanshan Gao, Andrew H. Smith, Jun Ye, Lili Cai, Linda M. Graham, Chaoyang Li
Cell Mol Life Sci. 2019 Sep; 76(17): 3449–3464. Published online 2019 Mar 27. doi: 10.1007/s00018-019-03081-w
PMCID:
PMC6698205
AbstractArticlePDF–2.9M
8.
Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors
Hyeonwoo Kim, Christiane D. Wrann, Mark Jedrychowski, Sara Vidoni, Yukiko Kitase, Kenichi Nagano, Chenhe Zhou, Joshua Chou, Virginia-Jeni A. Parkman, Scott J. Novick, Timothy S. Strutzenberg, Bruce D. Pascal, Phuong T. Le, Daniel J. Brooks, Alexander M. Roche, Kaitlyn K. Gerber, Laura Mattheis, Wenjing Chen, Hua Tu, Mary L. Bouxsein, Patrick R. Griffin, Roland Baron, Clifford J. Rosen, Lynda F. Bonewald, Bruce M. Spiegelman
Cell. Author manuscript; available in PMC 2019 Dec 13.
Published in final edited form as: Cell. 2018 Dec 13; 175(7): 1756–1768.e17. doi: 10.1016/j.cell.2018.10.025
Correction in:
Cell. 2019 Jul 11; 178(2): 507–508.
PMCID:
PMC6298040
AbstractArticlePDF–1.2M
9.
Complementary proteomics strategies capture an ataxin-1 interactome in Neuro-2a cells
Sunyuan Zhang, Nicholas A. Williamson, Marie A. Bogoyevitch
Sci Data. 2018; 5: 180262. Published online 2018 Nov 20. doi: 10.1038/sdata.2018.262
PMCID:
PMC6244183
AbstractArticlePDF–753K
10.
Proline hydroxylation in collagen supports integrin binding by two distinct mechanisms
Kalle H. Sipilä, Kati Drushinin, Pekka Rappu, Johanna Jokinen, Tiina A. Salminen, Antti M. Salo, Jarmo Käpylä, Johanna Myllyharju, Jyrki Heino
J Biol Chem. 2018 May 18; 293(20): 7645–7658. Published online 2018 Apr 3. doi: 10.1074/jbc.RA118.002200
PMCID:
PMC5961056
AbstractArticlePDF–2.7M
11.
Fancd2 in vivo interaction network reveals a non-canonical role in mitochondrial function
Tingting Zhang, Wei Du, Andrew F. Wilson, Satoshi H. Namekawa, Paul R. Andreassen, Amom Ruhikanta Meetei, Qishen Pang
Sci Rep. 2017; 7: 45626. Published online 2017 Apr 5. doi: 10.1038/srep45626
PMCID:
PMC5381226
AbstractArticlePDF–1.4M
12.
Overexpression of Prolyl-4-Hydroxylase-α1 Stabilizes but Increases Shear Stress-Induced Atherosclerotic Plaque in Apolipoprotein E-Deficient Mice
Xiao-qing Cao, Xin-xin Liu, Meng-meng Li, Yu Zhang, Liang Chen, Lin Wang, Ming-xue Di, Mei Zhang
Dis Markers. 2016; 2016: 1701637. Published online 2016 Oct 12. doi: 10.1155/2016/1701637
PMCID:
PMC5080484
AbstractArticlePDF–2.2M
13.
Wnt5a Deficiency Leads to Anomalies in Ureteric Tree Development, Tubular Epithelial Cell Organization and Basement Membrane Integrity Pointing to a Role in Kidney Collecting Duct Patterning
Ilkka Pietilä, Renata Prunskaite-Hyyryläinen, Susanna Kaisto, Elisavet Tika, Albertien M. van Eerde, Antti M. Salo, Leonardo Garma, Ilkka Miinalainen, Wout F. Feitz, Ernie M. H. F. Bongers, André Juffer, Nine V. A. M. Knoers, Kirsten Y. Renkema, Johanna Myllyharju, Seppo J. Vainio
PLoS One. 2016; 11(1): e0147171. Published online 2016 Jan 21. doi: 10.1371/journal.pone.0147171
PMCID:
PMC4721645
AbstractArticlePDF–5.2M
14.
Maternal bile acid transporter deficiency promotes neonatal demise
Yuanyuan Zhang, Fei Li, Yao Wang, Aaron Pitre, Zhong-ze Fang, Matthew W. Frank, Christopher Calabrese, Kristopher W. Krausz, Geoffrey Neale, Sharon Frase, Peter Vogel, Charles O. Rock, Frank J. Gonzalez, John D. Schuetz
Nat Commun. 2015; 6: 8186. Published online 2015 Sep 29. doi: 10.1038/ncomms9186
PMCID:
PMC4598356
AbstractArticlePDF–1.5M
15.
Severe Extracellular Matrix Abnormalities and Chondrodysplasia in Mice Lacking Collagen Prolyl 4-Hydroxylase Isoenzyme II in Combination with a Reduced Amount of Isoenzyme I
Ellinoora Aro, Antti M. Salo, Richa Khatri, Mikko Finnilä, Ilkka Miinalainen, Raija Sormunen, Outi Pakkanen, Tiina Holster, Raija Soininen, Carina Prein, Hauke Clausen-Schaumann, Attila Aszódi, Juha Tuukkanen, Kari I. Kivirikko, Ernestina Schipani, Johanna Myllyharju
J Biol Chem. 2015 Jul 3; 290(27): 16964–16978. Published online 2015 May 22. doi: 10.1074/jbc.M115.662635
PMCID:
PMC4505441
AbstractArticlePDF–5.2M
16.
An Argonaute 2 Switch Regulates Circulating miR-210 to Coordinate Hypoxic Adaptation across Cells
Andrew Hale, Changjin Lee, Sofia Annis, Pil-Ki Min, Reena Pande, Mark A. Creager, Colleen G. Julian, Lorna G. Moore, S. Alex Mitsialis, Sarah J. Hwang, Stella Kourembanas, Stephen Y. Chan
Biochim Biophys Acta. Author manuscript; available in PMC 2015 Nov 1.
Published in final edited form as: Biochim Biophys Acta. 2014 Nov; 1843(11): 2528–2542. Published online 2014 Jun 28. doi: 10.1016/j.bbamcr.2014.06.012
PMCID:
PMC4158026
AbstractArticlePDF–2.6M
17.
The Central Role of EED in the Orchestration of Polycomb Group Complexes
Qi Cao, Xiaoju Wang, Meng Zhao, Rendong Yang, Rohit Malik, Yuanyuan Qiao, Anton Poliakov, Anastasia K. Yocum, Yong Li, Wei Chen, Xuhong Cao, Xia Jiang, Arun Dahiya, Clair Harris, Felix Y. Feng, Sundeep Kalantry, Zhaohui S. Qin, Saravana M. Dhanasekaran, Arul M. Chinnaiyan
Nat Commun. Author manuscript; available in PMC 2014 Jul 24.
Published in final edited form as: Nat Commun. 2014; 5: 3127. doi: 10.1038/ncomms4127
PMCID:
PMC4073494
AbstractArticlePDF–2.1M
18.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M
19.
Hypoxia-inducible Factor-1 (HIF-1) but Not HIF-2 Is Essential for Hypoxic Induction of Collagen Prolyl 4-Hydroxylases in Primary Newborn Mouse Epiphyseal Growth Plate Chondrocytes
Ellinoora Aro, Richa Khatri, Rita Gerard-O'Riley, Laura Mangiavini, Johanna Myllyharju, Ernestina Schipani
J Biol Chem. 2012 Oct 26; 287(44): 37134–37144. Published online 2012 Aug 28. doi: 10.1074/jbc.M112.352872
PMCID:
PMC3481313
AbstractArticlePDF–2.1M
20.
Oct4 links multiple epigenetic pathways to the pluripotency network
Junjun Ding, Huilei Xu, Francesco Faiola, Avi Ma'ayan, Jianlong Wang
Cell Res. 2012 Jan; 22(1): 155–167. Published online 2011 Nov 15. doi: 10.1038/cr.2011.179
PMCID:
PMC3252465
AbstractArticlePDF–2.7M

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