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Select item 103243541.

An imbalance of netrin‐1 and DCC during nigral degeneration in experimental models and patients with Parkinson's disease

Ye Hua, Wenjing Han, Linfeng Zhou, Jing Gao, Jifeng Zhao, Nanshan Song, Bin Hu, Qingyu Yao, Yumin Liu, Deen Xu, Yunnan Lu, Yi Fan

CNS Neurosci Ther. 2023 Jul; 29(7): 1817–1829. Published online 2023 Feb 27. doi: 10.1111/cns.14141

PMCID:: PMC10324354

Abstract Article PDF–6.1M

Select item 91564062.

Corticolimbic DCC gene co-expression networks as predictors of impulsivity in children

Jose M. Restrepo-Lozano, Irina Pokhvisneva, Zihan Wang, Sachin Patel, Michael J. Meaney, Patricia P. Silveira, Cecilia Flores

Mol Psychiatry. 2022; 27(6): 2742–2750. Published online 2022 Apr 7. doi: 10.1038/s41380-022-01533-7

PMCID:: PMC9156406

Abstract Article PDF–2.4M

Select item 88910073.

Association between serum netrin-1, netrin-4 and risk of the acute coronary syndrome in patients with type 2 diabetes mellitus-A pilot study

Kumar Inderjeet, Prashant Shankarrao Adole, K.V. Vinod, Ajith Ananthakrishna Pillai

Indian Heart J. 2022 Jan-Feb; 74(1): 72–75. Published online 2021 Dec 4. doi: 10.1016/j.ihj.2021.11.186

PMCID:: PMC8891007

Abstract Article PDF–328K

Select item 81891004.

Transmembrane receptor DCC associates with protein synthesis machinery and regulates translation

Joseph Tcherkezian, Perry A. Brittis, Franziska Thomas, Philippe P. Roux, John G. Flanagan

Cell. Author manuscript; available in PMC 2021 Jun 9.

Published in final edited form as: Cell. 2021 Apr 29; 184(9): 2520. doi: 10.1016/j.cell.2021.04.018

Corrects:: Cell. 2010 May 14; 141(4): 632–644.

PMCID:: PMC8189100

Correction PDF–376K

Select item 81650305.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 79558496.

DCC gene network in the prefrontal cortex is associated with total brain volume in childhood

Alice Morgunova, Irina Pokhvisneva, Saara Nolvi, Sonja Entringer, Pathik Wadhwa, John Gilmore, Martin Styner, Claudia Buss, Roberto Britto Sassi, Geoffrey B.C. Hall, Kieran J. O’Donnell, Michael J. Meaney, Patricia P. Silveira, Cecilia A. Flores

J Psychiatry Neurosci. 2021 Jan; 46(1): E154–E163. Prepublished online 2020 Nov 18. doi: 10.1503/jpn.200081

PMCID:: PMC7955849

Abstract Article PDF–846K

Select item 78491687.

Netrin‐1 and its receptor DCC modulate survival and death of dopamine neurons and Parkinson’s disease features

Mélissa Jasmin, Eun Hee Ahn, Merja H Voutilainen, Joanna Fombonne, Catherine Guix, Tuulikki Viljakainen, Seong Su Kang, Li‐ying Yu, Mart Saarma, Patrick Mehlen, Keqiang Ye

EMBO J. 2021 Feb 1; 40(3): e105537. Published online 2020 Dec 22. doi: 10.15252/embj.2020105537

PMCID:: PMC7849168

Abstract Article PDF–2.7M

Select item 67302118.

Mapping Netrin Receptor Binding Reveals Domains of Unc5 Regulating Its Tyrosine Phosphorylation

Robert P. Kruger, Jeeyong Lee, Weiquan Li, Kun-Liang Guan

J Neurosci. 2004 Dec 1; 24(48): 10826–10834. doi: 10.1523/JNEUROSCI.3715-04.2004

PMCID:: PMC6730211

Abstract Article PDF–697K

Select item 61666829.

Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei

Domenico Fasci, Hugo van Ingen, Richard A. Scheltema, Albert J. R. Heck

Mol Cell Proteomics. 2018 Oct; 17(10): 2018–2033. Published online 2018 Jul 18. doi: 10.1074/mcp.RA118.000924

PMCID:: PMC6166682

Abstract Article PDF–3.8M

Select item 600226410.

Mammalian TRIM67 Functions in Brain Development and Behavior

Nicholas P. Boyer, Caroline Monkiewicz, Shalini Menon, Sheryl S. Moy, Stephanie L. Gupton

eNeuro. 2018 May-Jun; 5(3): ENEURO.0186-18.2018. Prepublished online 2018 May 29. Published online 2018 Jun 14. doi: 10.1523/ENEURO.0186-18.2018

Correction in:: eNeuro. 2019 Jul-Aug; 6(4): ENEURO.0281-19.2019.

PMCID:: PMC6002264

Abstract Article PDF–6.7M

Select item 589447811.

Mutations in DCC cause isolated agenesis of the corpus callosum with incomplete penetrance

Ashley P L Marsh, Delphine Heron, Timothy J Edwards, Angélique Quartier, Charles Galea, Caroline Nava, Agnès Rastetter, Marie-Laure Moutard, Vicki Anderson, Pierre Bitoun, Jens Bunt, Anne Faudet, Catherine Garel, Greta Gillies, Ilan Gobius, Justine Guegan, Solveig Heide, Boris Keren, Fabien Lesne, Vesna Lukic, Simone A Mandelstam, George McGillivray, Alissandra McIlroy, Aurélie Méneret, Cyril Mignot, Laura R Morcom, Sylvie Odent, Annalisa Paolino, Kate Pope, Florence Riant, Gail A Robinson, Megan Spencer-Smith, Myriam Srour, Sarah E M Stephenson, Rick Tankard, Oriane Trouillard, Quentin Welniarz, Amanda Wood, Alexis Brice, Guy Rouleau, Tania Attié-Bitach, Martin B Delatycki, Jean-Louis Mandel, David J Amor, Emmanuel Roze, Amélie Piton, Melanie Bahlo, Thierry Billette de Villemeur, Elliott H Sherr, Richard J Leventer, Linda J Richards, Paul J Lockhart, Christel Depienne

Nat Genet. Author manuscript; available in PMC 2018 Apr 11.

Published in final edited form as: Nat Genet. 2017 Apr; 49(4): 511–514. Published online 2017 Feb 27. doi: 10.1038/ng.3794

PMCID:: PMC5894478

Abstract Article PDF–222K

Select item 557690112.

TRIM9-dependent ubiquitination of DCC constrains kinase signaling, exocytosis, and axon branching

Melissa Plooster, Shalini Menon, Cortney C. Winkle, Fabio L. Urbina, Caroline Monkiewicz, Kristen D. Phend, Richard J. Weinberg, Stephanie L. Gupton

Mol Biol Cell. 2017 Sep 1; 28(18): 2374–2385. doi: 10.1091/mbc.E16-08-0594

PMCID:: PMC5576901

Abstract Article PDF–4.7M

Select item 555930613.

A genome-wide CRISPR screen identifies genes critical for resistance to FLT3 inhibitor AC220

Panpan Hou, Chao Wu, Yuchen Wang, Rui Qi, Dheeraj Bhavanasi, Zhixiang Zuo, Cedric Dos Santos, Shuliang Chen, Yu Chen, Hong Zheng, Hong Wang, Alexander Perl, Deyin Guo, Jian Huang

Cancer Res. Author manuscript; available in PMC 2018 Aug 15.

Published in final edited form as: Cancer Res. 2017 Aug 15; 77(16): 4402–4413. Published online 2017 Jun 16. doi: 10.1158/0008-5472.CAN-16-1627

PMCID:: PMC5559306

Abstract Article PDF–885K

Select item 551113014.

Netrin-1 promotes glioma growth by activating NF-κB via UNC5A

Jing-Ying Chen, Xiao-Xiao He, Chi Ma, Xin-Min Wu, Xi-Lin Wan, Zhen-Kai Xing, Qing-Qing Pei, Xian-Ping Dong, Dong-Xu Liu, Wen-Cheng Xiong, Xiao-Juan Zhu

Sci Rep. 2017; 7: 5454. Published online 2017 Jul 14. doi: 10.1038/s41598-017-05707-0

PMCID:: PMC5511130

Abstract Article PDF–12M

Select item 542866115.

Non cell-autonomous role of DCC in the guidance of the corticospinal tract at the midline

Quentin Welniarz, Marie-Pierre Morel, Oriane Pourchet, Cécile Gallea, Jean-Charles Lamy, Massimo Cincotta, Mohamed Doulazmi, Morgane Belle, Aurélie Méneret, Oriane Trouillard, Marta Ruiz, Vanessa Brochard, Sabine Meunier, Alain Trembleau, Marie Vidailhet, Alain Chédotal, Isabelle Dusart, Emmanuel Roze

Sci Rep. 2017; 7: 410. Published online 2017 Mar 24. doi: 10.1038/s41598-017-00514-z

PMCID:: PMC5428661

Abstract Article PDF–4.0M

Select item 523972416.

DCC confers susceptibility to depression-like behaviors in humans and mice and is regulated by miR-218

Angélica Torres-Berrío, Juan Pablo Lopez, Rosemary C. Bagot, Dominique Nouel, Gregory Dal-Bo, Santiago Cuesta, Lei Zhu, Colleen Manitt, Conrad Eng, Helen Cooper, Florian Storch, Gustavo Turecki, Eric J. Nestler, Cecilia Flores

Biol Psychiatry. Author manuscript; available in PMC 2018 Feb 15.

Published in final edited form as: Biol Psychiatry. 2017 Feb 15; 81(4): 306–315. Published online 2016 Aug 18. doi: 10.1016/j.biopsych.2016.08.017

PMCID:: PMC5239724

Abstract Article PDF–1.7M

Select item 507804917.

Genetic association of deleted in colorectal carcinoma variants with breast cancer risk: A case-control study

Xinghan Liu, Xijing Wang, Sidney W. Fu, Meng Wang, Huafeng Kang, Haitao Guan, Shuqun Zhang, Xiaobin Ma, Shuai Lin, Kang Liu, Yanjing Feng, Cong Dai, Zhijun Dai

Oncotarget. 2016 May 31; 7(22): 32765–32773. Published online 2016 Apr 26. doi: 10.18632/oncotarget.9024

PMCID:: PMC5078049

Abstract Article PDF–3.7M

Select item 505460218.

Selective depletion of tumour suppressors Deleted in Colorectal Cancer (DCC) and neogenin by environmental and endogenous serine proteases: linking diet and cancer

Caroline M. Forrest, Kara McNair, Maria C. J. Vincenten, L. Gail Darlington, Trevor W. Stone

BMC Cancer. 2016; 16: 772. Published online 2016 Oct 6. doi: 10.1186/s12885-016-2795-y

PMCID:: PMC5054602

Abstract Article PDF–2.8M

Select item 498280219.

A GENETIC RESPONSE SCORE FOR HYDROCHLOROTHIAZIDE USE: INSIGHTS FROM GENOMICS AND METABOLOMICS INTEGRATION

Mohamed H. Shahin, Yan Gong, Caitrin W. McDonough, Daniel M. Rotroff, Amber L Beitelshees, Timothy J. Garrett, John G. Gums, Alison Motsinger-Reif, Arlene B. Chapman, Stephen T. Turner, Eric Boerwinkle, Reginald F. Frye, Oliver Fiehn, Rhonda M. Cooper-DeHoff, Rima Kaddurah-Daouk, Julie A. Johnson

Hypertension. Author manuscript; available in PMC 2017 Sep 1.

Published in final edited form as: Hypertension. 2016 Sep; 68(3): 621–629. Published online 2016 Jul 5. doi: 10.1161/HYPERTENSIONAHA.116.07328

PMCID:: PMC4982802

Abstract Article PDF–1.6M

Select item 483830720.

Microarray Expression Data Identify DCC as a Candidate Gene for Early Meningioma Progression

Hans-Juergen Schulten, Deema Hussein, Fatima Al-Adwani, Sajjad Karim, Jaudah Al-Maghrabi, Mona Al-Sharif, Awatif Jamal, Fahad Al-Ghamdi, Saleh S. Baeesa, Mohammed Bangash, Adeel Chaudhary, Mohammed Al-Qahtani

PLoS One. 2016; 11(4): e0153681. Published online 2016 Apr 20. doi: 10.1371/journal.pone.0153681

PMCID:: PMC4838307

Abstract Article PDF–4.1M

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