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Items: 1 to 20 of 59

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Elevated TGFβ Signaling Contributes to Cerebral Small Vessel Disease in Mouse Models of Gould Syndrome
Kayla Branyan, Cassandre Labelle-Dumais, Xiaowei Wang, Genki Hayashi, Bryson Lee, Zoe Peltz, Seán Gorman, Bo Qiao Li, Mao Mao, Douglas B. Gould
Matrix Biol. Author manuscript; available in PMC 2024 Jan 1.
Published in final edited form as: Matrix Biol. 2023 Jan; 115: 48–70. Published online 2022 Nov 23. doi: 10.1016/j.matbio.2022.11.007
PMCID:
PMC10393528
AbstractArticlePDF–3.0M
3.
The extracellular matrix controls stem cell specification and crypt morphology in the developing and adult mouse gut
Rana Ramadan, Valérie M. Wouters, Sanne M. van Neerven, Nina E. de Groot, Tania Martins Garcia, Vanessa Muncan, Olivia D. Franklin, Michelle Battle, Karen Sue Carlson, Joshua Leach, Owen J. Sansom, Olivier Boulard, Mathias Chamaillard, Louis Vermeulen, Jan Paul Medema, David J. Huels
Biol Open. 2022 Dec 15; 11(12): bio059544. Published online 2022 Nov 23. doi: 10.1242/bio.059544
PMCID:
PMC9713296
AbstractArticlePDF–3.6M
4.
Detailed characterizations of cranial nerve anatomy in E14.5 mouse embryos/fetuses and their use as reference for diagnosing subtle, but potentially lethal malformations in mutants
Lukas F. Reissig, Stefan H. Geyer, Viola Winkler, Ester Preineder, Fabrice Prin, Robert Wilson, Antonella Galli, Catherine Tudor, Jaqueline K. White, Timothy J. Mohun, Wolfgang J. Weninger
Front Cell Dev Biol. 2022; 10: 1006620. Published online 2022 Nov 9. doi: 10.3389/fcell.2022.1006620
PMCID:
PMC9682249
AbstractArticlePDF–6.5M
5.
hnRNPU in Sertoli cells cooperates with WT1 and is essential for testicular development by modulating transcriptional factors Sox8/9
Yujiao Wen, Xixiang Ma, Xiaoli Wang, Fengli Wang, Juan Dong, Yanqing Wu, Chunyu Lv, Kuan Liu, Yan Zhang, Zhibing Zhang, Shuiqiao Yuan
Theranostics. 2021; 11(20): 10030–10046. Published online 2021 Oct 25. doi: 10.7150/thno.66819
PMCID:
PMC8581416
AbstractArticlePDF–3.5M
6.
FGF8 and BMP2 mediated dynamic regulation of dental mesenchyme proliferation and differentiation via Lhx8/Suv39h1 complex
Chen Zhou, Danying Chen, Jianhan Ren, Delan Huang, Runze Li, Haotian Luo, Chenyu Guan, Yang Cao, Weicai Wang
J Cell Mol Med. 2021 Mar; 25(6): 3051–3062. Published online 2021 Feb 13. doi: 10.1111/jcmm.16351
PMCID:
PMC7957265
AbstractArticlePDF–2.4M
7.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
8.
Accelerating functional gene discovery in osteoarthritis
Natalie C. Butterfield, Katherine F. Curry, Julia Steinberg, Hannah Dewhurst, Davide Komla-Ebri, Naila S. Mannan, Anne-Tounsia Adoum, Victoria D. Leitch, John G. Logan, Julian A. Waung, Elena Ghirardello, Lorraine Southam, Scott E. Youlten, J. Mark Wilkinson, Elizabeth A. McAninch, Valerie E. Vancollie, Fiona Kussy, Jacqueline K. White, Christopher J. Lelliott, David J. Adams, Richard Jacques, Antonio C. Bianco, Alan Boyde, Eleftheria Zeggini, Peter I. Croucher, Graham R. Williams, J. H. Duncan Bassett
Nat Commun. 2021; 12: 467. Published online 2021 Jan 20. doi: 10.1038/s41467-020-20761-5
Correction in:
Nat Commun. 2021; 12: 3302.
PMCID:
PMC7817695
AbstractArticlePDF–8.0M
9.
The Col4a2em1(IMPC)Wtsi mouse line: lessons from the Deciphering the Mechanisms of Developmental Disorders program
Lukas F. Reissig, Anna Nele Herdina, Julia Rose, Barbara Maurer-Gesek, Jenna L. Lane, Fabrice Prin, Robert Wilson, Emily Hardman, Antonella Galli, Catherine Tudor, Elizabeth Tuck, Cecilia Icoresi-Mazzeo, Jacqueline K. White, Ed Ryder, Diane Gleeson, David J. Adams, Stefan H. Geyer, Timothy J. Mohun, Wolfgang J. Weninger
Biol Open. 2019 Aug 15; 8(8): bio042895. Published online 2019 Jul 22. doi: 10.1242/bio.042895
PMCID:
PMC6737985
AbstractArticlePDF–4.1M
10.
Lhx8 ablation leads to massive autophagy of mouse oocytes associated with DNA damage
Laura D’Ignazio, Marc Michel, Melissa Beyer, Kassimier Thompson, Antonino Forabosco, David Schlessinger, Emanuele Pelosi
Biol Reprod. 2018 Apr; 98(4): 532–542. Published online 2018 Jan 10. doi: 10.1093/biolre/iox184
PMCID:
PMC6279113
AbstractArticlePDF–1.5M
11.
Post-translational modification of type IV collagen with 3-hydroxyproline affects its interactions with glycoprotein VI and nidogens 1 and 2
Nathan T. Montgomery, Keith D. Zientek, Elena N. Pokidysheva, Hans Peter Bächinger
J Biol Chem. 2018 Apr 20; 293(16): 5987–5999. Published online 2018 Feb 28. doi: 10.1074/jbc.RA117.000406
PMCID:
PMC5912474
AbstractArticlePDF–1.4M
12.
Type IV collagen α6 chain is a regulator of keratin 10 in keratinization of oral mucosal epithelium
Taishi Komori, Mitsuaki Ono, Emilio Satoshi Hara, Junji Ueda, Ha Thi Thu Nguyen, Ha Thi Nguyen, Tomoko Yonezawa, Takahiro Maeba, Aya Kimura-Ono, Takeshi Takarada, Ryusuke Momota, Kenji Maekawa, Takuo Kuboki, Toshitaka Oohashi
Sci Rep. 2018; 8: 2612. Published online 2018 Feb 8. doi: 10.1038/s41598-018-21000-0
PMCID:
PMC5805778
AbstractArticlePDF–2.3M
13.
Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression
Alexandra Naba, Karl R. Clauser, D. R. Mani, Steven A. Carr, Richard O. Hynes
Sci Rep. 2017; 7: 40495. Published online 2017 Jan 10. doi: 10.1038/srep40495
PMCID:
PMC5223159
AbstractArticlePDF–2.3M
14.
PDGFRβ regulates craniofacial development through homodimers and functional heterodimers with PDGFRα
Katherine A. Fantauzzo, Philippe Soriano
Genes Dev. 2016 Nov 1; 30(21): 2443–2458. doi: 10.1101/gad.288746.116
PMCID:
PMC5131783
AbstractArticlePDF–2.5M
15.
Type IV collagen drives alveolar epithelial–endothelial association and the morphogenetic movements of septation
Maria Loscertales, Fotini Nicolaou, Marion Jeanne, Mauro Longoni, Douglas B. Gould, Yunwei Sun, Faouzi I. Maalouf, Nandor Nagy, Patricia K. Donahoe
BMC Biol. 2016; 14: 59. Published online 2016 Jul 13. doi: 10.1186/s12915-016-0281-2
Correction in:
BMC Biol. 2016; 14(1): 73.
PMCID:
PMC4942891
AbstractArticlePDF–4.2M
16.
Thyroid follicle development requires Smad1/5- and endothelial cell-dependent basement membrane assembly
Mylah Villacorte, Anne-Sophie Delmarcelle, Manon Lernoux, Mahé Bouquet, Pascale Lemoine, Jennifer Bolsée, Lieve Umans, Susana Chuva de Sousa Lopes, Patrick Van Der Smissen, Takako Sasaki, Guido Bommer, Patrick Henriet, Samuel Refetoff, Frédéric P. Lemaigre, An Zwijsen, Pierre J. Courtoy, Christophe E. Pierreux
Development. 2016 Jun 1; 143(11): 1958–1970. doi: 10.1242/dev.134171
PMCID:
PMC4920163
AbstractArticle
17.
Developmental distribution of collagen IV isoforms and relevance to ocular diseases
Xiaoyang Bai, David J. Dilworth, Yi-Chinn Weng, Douglas B. Gould
Matrix Biol. Author manuscript; available in PMC 2016 Feb 10.
Published in final edited form as: Matrix Biol. 2009 May; 28(4): 194–201. Published online 2009 Mar 9. doi: 10.1016/j.matbio.2009.02.004
PMCID:
PMC4749355
AbstractArticlePDF–899K
18.
Col4a1 mutations cause progressive retinal neovascular defects and retinopathy
Marcel V. Alavi, Mao Mao, Bradley T. Pawlikowski, Manana Kvezereli, Jacque L. Duncan, Richard T. Libby, Simon W. M. John, Douglas B. Gould
Sci Rep. 2016; 6: 18602. Published online 2016 Jan 27. doi: 10.1038/srep18602
PMCID:
PMC4728690
AbstractArticlePDF–6.9M
19.
Wnt5a Deficiency Leads to Anomalies in Ureteric Tree Development, Tubular Epithelial Cell Organization and Basement Membrane Integrity Pointing to a Role in Kidney Collecting Duct Patterning
Ilkka Pietilä, Renata Prunskaite-Hyyryläinen, Susanna Kaisto, Elisavet Tika, Albertien M. van Eerde, Antti M. Salo, Leonardo Garma, Ilkka Miinalainen, Wout F. Feitz, Ernie M. H. F. Bongers, André Juffer, Nine V. A. M. Knoers, Kirsten Y. Renkema, Johanna Myllyharju, Seppo J. Vainio
PLoS One. 2016; 11(1): e0147171. Published online 2016 Jan 21. doi: 10.1371/journal.pone.0147171
PMCID:
PMC4721645
AbstractArticlePDF–5.2M
20.
Molecular and Genetic Analysis of Collagen Type IV Mutant Mouse Models of Spontaneous Intracerebral Hemorrhage Identify Mechanisms for Stroke Prevention
Marion Jeanne, Jeff Jorgensen, Douglas B. Gould
Circulation. Author manuscript; available in PMC 2016 May 5.
Published in final edited form as: Circulation. 2015 May 5; 131(18): 1555–1565. Published online 2015 Mar 9. doi: 10.1161/CIRCULATIONAHA.114.013395
PMCID:
PMC4497509
AbstractArticlePDF–1.0M

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