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Select item 110740191.

NCS-1 protein regulates TRPA1 channel through the PI3K pathway in breast cancer and neuronal cells

Julio C. Sánchez, Alexander Alemán, Juan F. Henao, Juan C. Olaya, Barbara E. Ehrlich

J Physiol Biochem. 2024; 80(2): 451–463. Published online 2024 Apr 2. doi: 10.1007/s13105-024-01016-z

PMCID:: PMC11074019

Abstract Article PDF–2.2M

Select item 100729062.

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity

Martin Golkowski, Andrea Lius, Tanmay Sapre, Ho-Tak Lau, Taylor Moreno, Dustin J. Maly, Shao-En Ong

Mol Cell. Author manuscript; available in PMC 2023 Apr 4.

Published in final edited form as: Mol Cell. 2023 Mar 2; 83(5): 803–818.e8. Published online 2023 Feb 2. doi: 10.1016/j.molcel.2023.01.015

PMCID:: PMC10072906

Abstract Article PDF–4.2M

Select item 91369433.

Interactomic analysis reveals a homeostatic role for the HIV restriction factor TRIM5α in mitophagy

Bhaskar Saha, Michelle Salemi, Geneva L. Williams, Seeun Oh, Michael L. Paffett, Brett Phinney, Michael A. Mandell

Cell Rep. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell Rep. 2022 May 10; 39(6): 110797. doi: 10.1016/j.celrep.2022.110797

PMCID:: PMC9136943

Abstract Article PDF–3.2M

Select item 91197364.

OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization

Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti

Science. Author manuscript; available in PMC 2022 Sep 11.

Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983

PMCID:: PMC9119736

Abstract Article PDF–3.3M

Select item 86666655.

CD95/Fas suppresses NF-κB activation through recruitment of KPC2 in a CD95L/FasL-independent mechanism

Jean-Philippe Guégan, Justine Pollet, Christophe Ginestier, Emmanuelle Charafe-Jauffret, Marcus E. Peter, Patrick Legembre

iScience. 2021 Dec 17; 24(12): 103538. Published online 2021 Dec 1. doi: 10.1016/j.isci.2021.103538

PMCID:: PMC8666665

Abstract Article PDF–3.2M

Select item 86236526.

Disulfide Dimerization of Neuronal Calcium Sensor-1: Implications for Zinc and Redox Signaling

Viktoriia E. Baksheeva, Alexey V. Baldin, Arthur O. Zalevsky, Aliya A. Nazipova, Alexey S. Kazakov, Vasiliy I. Vladimirov, Neonila V. Gorokhovets, François Devred, Pavel P. Philippov, Alexandr V. Bazhin, Andrey V. Golovin, Andrey A. Zamyatnin, Jr., Dmitry V. Zinchenko, Philipp O. Tsvetkov, Sergei E. Permyakov, Evgeni Yu. Zernii

Int J Mol Sci. 2021 Nov; 22(22): 12602. Published online 2021 Nov 22. doi: 10.3390/ijms222212602

PMCID:: PMC8623652

Abstract Article PDF–5.9M

Select item 84657757.

Hepatocellular Carcinoma Outcome is Predicted by Expression of Neuronal Calcium Sensor 1

Daniel Schuette, Lauren M. Moore, Marie E. Robert, Tamar H. Taddei, Barbara E. Ehrlich

Cancer Epidemiol Biomarkers Prev. Author manuscript; available in PMC 2021 Sep 26.

Published in final edited form as: Cancer Epidemiol Biomarkers Prev. 2018 Sep; 27(9): 1091–1100. Published online 2018 May 22. doi: 10.1158/1055-9965.EPI-18-0167

PMCID:: PMC8465775

Abstract Article PDF–943K

Select item 81650308.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 79666639.

Disorder in a two-domain neuronal Ca²⁺-binding protein regulates domain stability and dynamics using ligand mimicry

Lasse Staby, Katherine R. Kemplen, Amelie Stein, Michael Ploug, Jane Clarke, Karen Skriver, Pétur O. Heidarsson, Birthe B. Kragelund

Cell Mol Life Sci. 2021 Mar; 78(5): 2263–2278. Published online 2020 Sep 16. doi: 10.1007/s00018-020-03639-z

PMCID:: PMC7966663

Abstract Article PDF–3.3M

Select item 742732710.

Kinase Interaction Network Expands Functional and Disease Roles of Human Kinases

Marija Buljan, Rodolfo Ciuffa, Audrey van Drogen, Anton Vichalkovski, Martin Mehnert, George Rosenberger, Sohyon Lee, Markku Varjosalo, Lucia Espona Pernas, Vincent Spegg, Berend Snijder, Ruedi Aebersold, Matthias Gstaiger

Mol Cell. 2020 Aug 6; 79(3): 504–520.e9. doi: 10.1016/j.molcel.2020.07.001

PMCID:: PMC7427327

Abstract Article

Select item 726628511.

Neuronal Calcium Sensor 1 is up‐regulated in response to stress to promote cell survival and motility in cancer cells

Henrike K. Grosshans, Tom T. Fischer, Julia A. Steinle, Allison L. Brill, Barbara E. Ehrlich

Mol Oncol. 2020 Jun; 14(6): 1134–1151. Published online 2020 Apr 28. doi: 10.1002/1878-0261.12678

PMCID:: PMC7266285

Abstract Article PDF–2.6M

Select item 716998312.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 707245113.

Membrane Binding of Neuronal Calcium Sensor-1: Highly Specific Interaction with Phosphatidylinositol-3-Phosphate

Viktoriia E. Baksheeva, Ekaterina L. Nemashkalova, Alexander M. Firsov, Arthur O. Zalevsky, Vasily I. Vladimirov, Natalia K. Tikhomirova, Pavel P. Philippov, Andrey A. Zamyatnin, Jr., Dmitry V. Zinchenko, Yuri N. Antonenko, Sergey E. Permyakov, Evgeni Yu. Zernii

Biomolecules. 2020 Feb; 10(2): 164. Published online 2020 Jan 21. doi: 10.3390/biom10020164

PMCID:: PMC7072451

Abstract Article PDF–2.2M

Select item 694410314.

NCS‐1 expression is higher in basal breast cancers and regulates calcium influx and cytotoxic responses to doxorubicin

Alice H. L. Bong, Mélanie Robitaille, Michael J. G. Milevskiy, Sarah J. Roberts‐Thomson, Gregory R. Monteith

Mol Oncol. 2020 Jan; 14(1): 87–104. Published online 2019 Nov 11. doi: 10.1002/1878-0261.12589

PMCID:: PMC6944103

Abstract Article PDF–2.8M

Select item 684168415.

Cav2.3 channels contribute to dopaminergic neuron loss in a model of Parkinson’s disease

Julia Benkert, Simon Hess, Shoumik Roy, Dayne Beccano-Kelly, Nicole Wiederspohn, Johanna Duda, Carsten Simons, Komal Patil, Aisylu Gaifullina, Nadja Mannal, Elena Dragicevic, Desirée Spaich, Sonja Müller, Julia Nemeth, Helene Hollmann, Nora Deuter, Yassine Mousba, Christian Kubisch, Christina Poetschke, Joerg Striessnig, Olaf Pongs, Toni Schneider, Richard Wade-Martins, Sandip Patel, Rosanna Parlato, Tobias Frank, Peter Kloppenburg, Birgit Liss

Nat Commun. 2019; 10: 5094. Published online 2019 Nov 8. doi: 10.1038/s41467-019-12834-x

PMCID:: PMC6841684

Abstract Article PDF–6.5M

Select item 675779616.

Interaction with Neuronal Calcium Sensor NCS-1 Mediates Desensitization of the D2 Dopamine Receptor

Nadine Kabbani, Laszlo Negyessy, Ridwan Lin, Patricia Goldman-Rakic, Robert Levenson

J Neurosci. 2002 Oct 1; 22(19): 8476–8486. doi: 10.1523/JNEUROSCI.22-19-08476.2002

PMCID:: PMC6757796

Abstract Article PDF–679K

Select item 662870517.

Dopamine Receptor Interacting Proteins: Targeting Neuronal Calcium Sensor-1/D2 Dopamine Receptor Interaction for Antipsychotic Drug Development

Nadine Kabbani, Mathew P. Woll, Jacob C. Nordman, Robert Levenson

Curr Drug Targets. Author manuscript; available in PMC 2019 Jul 15.

Published in final edited form as: Curr Drug Targets. 2012 Jan; 13(1): 72–79. doi: 10.2174/138945012798868515

PMCID:: PMC6628705

Abstract Article PDF–613K

Select item 641591818.

Temperature-dependent Conformational Properties of Human Neuronal Calcium Sensor-1 Protein Revealed by All-atom Simulations

Yuzhen Zhu, Buyong Ma, Ruth Nussinov, Qingwen Zhang

J Phys Chem B. Author manuscript; available in PMC 2019 Mar 13.

Published in final edited form as: J Phys Chem B. 2016 Apr 14; 120(14): 3551–3559. Published online 2016 Mar 31. doi: 10.1021/acs.jpcb.5b12299

PMCID:: PMC6415918

Abstract Article PDF–1.3M

Select item 629825419.

A protein-protein interaction map of the TNF-induced NF-κB signal transduction pathway

Emmy Van Quickelberghe, Delphine De Sutter, Geert van Loo, Sven Eyckerman, Kris Gevaert

Sci Data. 2018; 5: 180289. Published online 2018 Dec 18. doi: 10.1038/sdata.2018.289

PMCID:: PMC6298254

Abstract Article PDF–1.4M

Select item 553161120.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

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