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Select item 93389981.

Cholesterol sulfate alleviates ulcerative colitis by promoting cholesterol biosynthesis in colonic epithelial cells

Dongke Xu, Ruijun Ma, Yi Ju, Xiaowei Song, Baolin Niu, Wenting Hong, Rong Wang, Qin Yang, Zhi Zhao, Yuchen Zhang, Yufan Zheng, Qianming Bai, Mingfang Lv, Ning Sun, Xiaobo Li

Nat Commun. 2022; 13: 4428. Published online 2022 Jul 30. doi: 10.1038/s41467-022-32158-7

PMCID:: PMC9338998

Abstract Article PDF–5.3M

Select item 86719052.

The promoter hypermethylation of SULT2B1 accelerates esophagus tumorigenesis via downregulated PER1

Zhuo Li, Meng‐Yan Li, Ling‐Ling Wang, Lei Li, Qing‐Yun Chen, Ying‐Hui Zhu, Yan Li, Yan‐ru Qin, Xin‐Yuan Guan

Thorac Cancer. 2021 Dec; 12(24): 3370–3379. Published online 2021 Nov 2. doi: 10.1111/1759-7714.14211

Correction in:: Thorac Cancer. 2022 Sep; 13(18): 2664–2665.

PMCID:: PMC8671905

Abstract Article PDF–2.0M

Select item 85814213.

Sult2b1 deficiency exacerbates ischemic stroke by promoting pro-inflammatory macrophage polarization in mice

Yan Wang, Haojie Jin, Yafang Wang, Yang Yao, Cuixia Yang, Jihong Meng, Xiaomu Tan, Yu Nie, Lixiang Xue, Baohui Xu, Heng Zhao, Feng Wang

Theranostics. 2021; 11(20): 10074–10090. Published online 2021 Nov 1. doi: 10.7150/thno.61646

PMCID:: PMC8581421

Abstract Article PDF–3.1M

Select item 79062184.

Reduced SULT2B1b expression alleviates ox-LDL-induced inflammation by upregulating miR-148-3P via inhibiting the IKKβ/NF-κB pathway in macrophages

Mengzhuo Yin, Jianwen Lu, Zhongzhou Guo, Yanan Zhang, Jichen Liu, Tongwei Wu, Kai Guo, Tiantian Luo, Zhigang Guo

Aging (Albany NY) 2021 Feb 15; 13(3): 3428–3442. Published online 2021 Jan 10. doi: 10.18632/aging.202273

PMCID:: PMC7906218

Abstract Article PDF–1.4M

Select item 73417175.

Inhibitory Interplay of SULT2B1b Sulfotransferase with AKR1C3 Aldo-keto Reductase in Prostate Cancer

Sulgi Park, Chung-Seog Song, Chun-Lin Lin, Shoulei Jiang, Pawel A Osmulski, Chiou-Miin Wang, Brett T Marck, Alvin M Matsumoto, Colm Morrissey, Maria E Gaczynska, Yidong Chen, Elahe A Mostaghel, Bandana Chatterjee

Endocrinology. 2020 Feb; 161(2): bqz042. Published online 2020 Jan 2. doi: 10.1210/endocr/bqz042

PMCID:: PMC7341717

Abstract Article

Select item 68748246.

Hydroxysteroid sulfotransferase 2B1 affects gastric epithelial function and carcinogenesis induced by a carcinogenic agent

Wenting Hong, Fenghua Guo, Mingjie Yang, Dongke Xu, Ziyan Zhuang, Baolin Niu, Qianming Bai, Xiaobo Li

Lipids Health Dis. 2019; 18: 203. Published online 2019 Nov 22. doi: 10.1186/s12944-019-1149-6

PMCID:: PMC6874824

Abstract Article PDF–6.7M

Select item 64919157.

An Unexpected Role of Cholesterol Sulfotransferase and its Regulation in Sensitizing Mice to Acetaminophen-Induced Liver Injury

Yunqi An, Pengcheng Wang, Pengfei Xu, Hung-Chun Tung, Yang Xie, Levent Kirisci, Meishu Xu, Songrong Ren, Xin Tian, Xiaochao Ma, Wen Xie

Mol Pharmacol. 2019 Jun; 95(6): 597–605. Published online 2019 Jun. doi: 10.1124/mol.118.114819

PMCID:: PMC6491915

Abstract Article PDF–3.0M

Select item 58548338.

Regulation of Cholesterol Sulfotransferase SULT2B1b by Hepatocyte Nuclear Factor 4α Constitutes a Negative Feedback Control of Hepatic Gluconeogenesis

Yuhan Bi, Xiongjie Shi, Junjie Zhu, Xiudong Guan, Wojciech G. Garbacz, Yixian Huang, Li Gao, Jiong Yan, Meishu Xu, Songrong Ren, Shunlin Ren, Yulan Liu, Xiaochao Ma, Song Li, Wen Xie

Mol Cell Biol. 2018 Apr 1; 38(7): e00654-17. Prepublished online 2018 Jan 29. Published online 2018 Mar 15. doi: 10.1128/MCB.00654-17

PMCID:: PMC5854833

Abstract Article PDF–3.0M

Select item 54737279.

Mutations in SULT2B1 Cause Autosomal-Recessive Congenital Ichthyosis in Humans

Lisa Heinz, Gwang-Jin Kim, Slaheddine Marrakchi, Julie Christiansen, Hamida Turki, Marc-Alexander Rauschendorf, Mark Lathrop, Ingrid Hausser, Andreas D. Zimmer, Judith Fischer

Am J Hum Genet. 2017 Jun 1; 100(6): 926–939. Published online 2017 Jun 1. doi: 10.1016/j.ajhg.2017.05.007

PMCID:: PMC5473727

Abstract Article PDF–3.1M

Select item 491601610.

Inhibition of T cell receptor signaling by cholesterol sulfate, a naturally occurring derivative of membrane cholesterol

Feng Wang, Katharina Beck-García, Carina Zorzin, Wolfgang W. A. Schamel, Mark M. Davis

Nat Immunol. Author manuscript; available in PMC 2016 Nov 23.

Published in final edited form as: Nat Immunol. 2016 Jul; 17(7): 844–850. Published online 2016 May 23. doi: 10.1038/ni.3462

PMCID:: PMC4916016

Abstract Article PDF–1.6M

Select item 392000811.

Sulfation of 25-hydroxycholesterol regulates lipid metabolism, inflammatory responses, and cell proliferation

Shunlin Ren, Yanxia Ning

Am J Physiol Endocrinol Metab. 2014 Jan 15; 306(2): E123–E130. Published online 2013 Dec 3. doi: 10.1152/ajpendo.00552.2013

PMCID:: PMC3920008

Abstract Article

Select item 391151112.

Cholesterol Sulfate and Cholesterol Sulfotransferase Inhibit Gluconeogenesis by Targeting Hepatocyte Nuclear Factor 4α

Xiongjie Shi, Qiuqiong Cheng, Leyuan Xu, Jiong Yan, Mengxi Jiang, Jinhan He, Meishu Xu, Maja Stefanovic-Racic, Ian Sipula, Robert Martin O'Doherty, Shunlin Ren, Wen Xie

Mol Cell Biol. 2014 Feb; 34(3): 485–497. doi: 10.1128/MCB.01094-13

PMCID:: PMC3911511

Abstract Article PDF–3.0M

Select item 357241013.

A conditional knockout resource for the genome–wide study of mouse gene function

William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley

Nature. Author manuscript; available in PMC 2013 Feb 14.

Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163

PMCID:: PMC3572410

Abstract Article PDF–1.1M

Select item 342310414.

Cytosolic sulfotransferase 2B1b promotes hepatocyte proliferation gene expression in vivo and in vitro

Xin Zhang, Qianming Bai, Leyuan Xu, Genta Kakiyama, William M. Pandak, Jr., Zhigang Zhang, Shunlin Ren

Am J Physiol Gastrointest Liver Physiol. 2012 Aug 1; 303(3): G344–G355. Published online 2012 Jun 7. doi: 10.1152/ajpgi.00403.2011

PMCID:: PMC3423104

Abstract Article

Select item 334248115.

Oxysterol Sulfation by SULT2B1b Suppresses LXR/SREBP-1c Signaling Pathway and Reduces Serum and Hepatic Lipids in Mouse Models of NAFLD

Qianming Bai, Xin Zhang, Leyuan Xu, Genta Kakiyama, Douglas Heuman, Arun Sanyal, William M. Pandak, Lianhua Yin, Wen Xie, Shunlin Ren

Metabolism. Author manuscript; available in PMC 2013 Jun 1.

Published in final edited form as: Metabolism. 2012 Jun; 61(6): 836–845. Published online 2012 Jan 5. doi: 10.1016/j.metabol.2011.11.014

PMCID:: PMC3342481

Abstract Article PDF–3.0M

Select item 317805916.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 302253417.

A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo

Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio

PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582