PMC Links for GEO Profiles (Select 103907527) - PMC

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 86081484.

p190RhoGAP Filters Competing Signals to Resolve Axon Guidance Conflicts

Dario Bonanomi, Fabiola Valenza, Onanong Chivatakarn, Matthew J. Sternfeld, Shawn P. Driscoll, Aaron Aslanian, Karen Lettieri, Miriam Gullo, Aurora Badaloni, Joseph W. Lewcock, Tony Hunter, Samuel L. Pfaff

Neuron. Author manuscript; available in PMC 2021 Nov 22.

Published in final edited form as: Neuron. 2019 May 8; 102(3): 602–620.e9. Published online 2019 Mar 19. doi: 10.1016/j.neuron.2019.02.034

PMCID:: PMC8608148

Abstract Article PDF–4.2M

Select item 77466725.

RASA1-driven cellular export of collagen IV is required for the development of lymphovenous and venous valves in mice

Di Chen, Xin Geng, Philip E. Lapinski, Michael J. Davis, R. Sathish Srinivasan, Philip D. King

Development. 2020 Dec 1; 147(23): dev192351. Published online 2020 Dec 7. doi: 10.1242/dev.192351

PMCID:: PMC7746672

Abstract Article

Select item 67153646.

RASA1-dependent cellular export of collagen IV controls blood and lymphatic vascular development

Di Chen, Joyce M. Teng, Paula E. North, Philip E. Lapinski, Philip D. King

J Clin Invest. 2019 Sep 3; 129(9): 3545–3561. Published online 2019 Aug 5. doi: 10.1172/JCI124917

PMCID:: PMC6715364

Abstract Article PDF–38M

Select item 54907787.

RASA1 regulates the function of lymphatic vessel valves in mice

Philip E. Lapinski, Beth A. Lubeck, Di Chen, Abbas Doosti, Scott D. Zawieja, Michael J. Davis, Philip D. King

J Clin Invest. 2017 Jun 30; 127(7): 2569–2585. Published online 2017 May 22. doi: 10.1172/JCI89607

PMCID:: PMC5490778

Abstract Article PDF–4.1M

Select item 53082188.

The Proximal Signaling Network of the BCR-ABL1 Oncogene Shows a Modular Organization

Björn Titz, Tracey Low, Evangelia Komisopoulou, Sharon S Chen, Liudmilla Rubbi, Thomas G Graeber

Oncogene. Author manuscript; available in PMC 2017 Feb 14.

Published in final edited form as: Oncogene. 2010 Nov 4; 29(44): 5895–5910. Published online 2010 Aug 9. doi: 10.1038/onc.2010.331

PMCID:: PMC5308218

Abstract Article PDF–3.8M

Select item 44754129.

Co-deletion of the Ras GTPase-activating proteins Neurofibromin 1 (NF1) and p120 RasGAP (RASA1) in T cells results in the development of T cell acute lymphoblastic leukemia

Beth A. Lubeck, Philip E. Lapinski, Jennifer A. Oliver, Olga Ksionda, Luis F. Parada, Yuan Zhu, Ivan Maillard, Mark Chiang, Jeroen Roose, Philip D. King

J Immunol. Author manuscript; available in PMC 2016 Jul 1.

Published in final edited form as: J Immunol. 2015 Jul 1; 195(1): 31–35. Published online 2015 May 22. doi: 10.4049/jimmunol.1402639

PMCID:: PMC4475412

Abstract Article PDF–388K

Select item 425849910.

Blood Vascular Abnormalities in Rasa1^R780Q Knockin Mice: Implications for the Pathogenesis of Capillary Malformation–Arteriovenous Malformation

Beth A. Lubeck, Philip E. Lapinski, Timothy J. Bauler, Jennifer A. Oliver, Elizabeth D. Hughes, Thomas L. Saunders, Philip D. King

Am J Pathol. 2014 Dec; 184(12): 3163–3169. doi: 10.1016/j.ajpath.2014.08.018

PMCID:: PMC4258499

Abstract Article PDF–1.6M

Select item 396495511.

The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data

Gautier Koscielny, Gagarine Yaikhom, Vivek Iyer, Terrence F. Meehan, Hugh Morgan, Julian Atienza-Herrero, Andrew Blake, Chao-Kung Chen, Richard Easty, Armida Di Fenza, Tanja Fiegel, Mark Grifiths, Alan Horne, Natasha A. Karp, Natalja Kurbatova, Jeremy C. Mason, Peter Matthews, Darren J. Oakley, Asfand Qazi, Jack Regnart, Ahmad Retha, Luis A. Santos, Duncan J. Sneddon, Jonathan Warren, Henrik Westerberg, Robert J. Wilson, David G. Melvin, Damian Smedley, Steve D. M. Brown, Paul Flicek, William C. Skarnes, Ann-Marie Mallon, Helen Parkinson

Nucleic Acids Res. 2014 Jan 1; 42(Database issue): D802–D809. Published online 2013 Nov 3. doi: 10.1093/nar/gkt977

PMCID:: PMC3964955

Abstract Article PDF–5.7M

Select item 394586612.

Unbiased RNAi screen for hepcidin regulators links hepcidin suppression to proliferative Ras/RAF and nutrient-dependent mTOR signaling

Katarzyna Mleczko-Sanecka, Franziska Roche, Ana Rita da Silva, Debora Call, Flavia D’Alessio, Anan Ragab, Philip E. Lapinski, Ramesh Ummanni, Ulrike Korf, Christopher Oakes, Georg Damm, Lorenza A. D’Alessandro, Ursula Klingmüller, Philip D. King, Michael Boutros, Matthias W. Hentze, Martina U. Muckenthaler

Blood. 2014 Mar 6; 123(10): 1574–1585. Prepublished online 2014 Jan 2. doi: 10.1182/blood-2013-07-515957

PMCID:: PMC3945866

Abstract Article

Select item 386649513.

MicroRNA-132 Is Enriched in Developing Axons, Locally Regulates Rasa1 mRNA, and Promotes Axon Extension

Melissa L. Hancock, Nicolas Preitner, Jie Quan, John G. Flanagan

J Neurosci. 2014 Jan 1; 34(1): 66–78. doi: 10.1523/JNEUROSCI.3371-13.2014

PMCID:: PMC3866495

Abstract Article PDF–3.3M

Select item 369494914.

Role of mTOR, Bad, and Survivin in RasGAP Fragment N-Mediated Cell Protection

Nieves Peltzer, Güliz Vanli, Jiang-Yan Yang, Christian Widmann

PLoS One. 2013; 8(6): e68123. Published online 2013 Jun 27. doi: 10.1371/journal.pone.0068123

PMCID:: PMC3694949

Abstract Article PDF–1.2M

Select item 366667515.

Lymphatic abnormalities are associated with RASA1 gene mutations in mouse and man

Patricia E. Burrows, Manuel L. Gonzalez-Garay, John C. Rasmussen, Melissa B. Aldrich, Renie Guilliod, Erik A. Maus, Caroline E. Fife, Sunkuk Kwon, Philip E. Lapinski, Philip D. King, Eva M. Sevick-Muraca

Proc Natl Acad Sci U S A. 2013 May 21; 110(21): 8621–8626. Published online 2013 May 6. doi: 10.1073/pnas.1222722110

PMCID:: PMC3666675

Abstract Article PDF–1.0M

Select item 361101916.

MicroRNA-31 Activates the RAS Pathway and Functions as an Oncogenic MicroRNA in Human Colorectal Cancer by Repressing RAS p21 GTPase Activating Protein 1 (RASA1)

Defang Sun, Feng Yu, Yutao Ma, Ran Zhao, Xi Chen, Jie Zhu, Chen-Yu Zhang, Jiangning Chen, Junfeng Zhang

J Biol Chem. 2013 Mar 29; 288(13): 9508–9518. Published online 2013 Jan 15. doi: 10.1074/jbc.M112.367763

PMCID:: PMC3611019

Abstract Article PDF–2.9M

Select item 361099817.

Negative Regulation of the RalGAP Complex by 14-3-3

Dara Leto, Maeran Uhm, Anja Williams, Xiao-wei Chen, Alan R. Saltiel

J Biol Chem. 2013 Mar 29; 288(13): 9272–9283. Published online 2013 Feb 5. doi: 10.1074/jbc.M112.426106

PMCID:: PMC3610998

Abstract Article PDF–3.0M

Select item 348619118.

Caspase-3 Protects Stressed Organs against Cell Death

Hadi Khalil, Nieves Peltzer, Joël Walicki, Jiang-Yan Yang, Gilles Dubuis, Noémie Gardiol, Werner Held, Paul Bigliardi, Benjamin Marsland, Lucas Liaudet, Christian Widmann

Mol Cell Biol. 2012 Nov; 32(22): 4523–4533. doi: 10.1128/MCB.00774-12

PMCID:: PMC3486191

Abstract Article PDF–4.4M

Select item 347957219.

Development of promyelocytic leukemia zinc finger-expressing innate CD4 T cells requires stronger T-cell receptor signals than conventional CD4 T cells

Yu Qiao, Lingqiao Zhu, Hanief Sofi, Philip E. Lapinski, Reiko Horai, Kristen Mueller, Gretta L. Stritesky, Xi He, Hung-Sia Teh, David L. Wiest, Dietmar J. Kappes, Philip D. King, Kristin A. Hogquist, Pamela L. Schwartzberg, Derek B. Sant’Angelo, Cheong-Hee Chang

Proc Natl Acad Sci U S A. 2012 Oct 2; 109(40): 16264–16269. Published online 2012 Sep 17. doi: 10.1073/pnas.1207528109

PMCID:: PMC3479572

Abstract Article PDF–1.0M

Select item 326677420.

RASA1 maintains the lymphatic vasculature in a quiescent functional state in mice

Philip E. Lapinski, Sunkuk Kwon, Beth A. Lubeck, John E. Wilkinson, R. Sathish Srinivasan, Eva Sevick-Muraca, Philip D. King

J Clin Invest. 2012 Feb 1; 122(2): 733–747. Published online 2012 Jan 9. doi: 10.1172/JCI46116

PMCID:: PMC3266774

Abstract Article PDF–1.8M

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