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Select item 111599281.

Rab5a overexpression promoting ovarian cancer cell proliferation may be associated with APPL1‐related epidermal growth factor signaling pathway

Zhen Zhao, Xiang‐Fan Liu, Hua‐Cheng Wu, Shu‐Biao Zou, Jia‐Yi Wang, Pei‐Hua Ni, Xin‐Hua Chen, Qi‐Shi Fan

Cancer Sci. 2010 Jun; 101(6): 1454–1462. Published online 2010 Mar 10. doi: 10.1111/j.1349-7006.2010.01558.x

PMCID:: PMC11159928

Abstract Article PDF–2.0M

Select item 110463562.

RAB5A in triple-negative breast cancer: a critical role in macrophage reshaping in an exosomal miR-21-dependent manner

Lei Qiao, Chao Dong, Wenlei Jia, Gang Sun

Endocr Relat Cancer. 2024 May 1; 31(5): e230257. Prepublished online 2024 Mar 12. Published online 2024 Apr 12. doi: 10.1530/ERC-23-0257

PMCID:: PMC11046356

Abstract Article PDF–6.1M

Select item 107562753.

A genome-wide CRISPR/Cas9 screen identifies a role for Rab5A and early endosomes in hepatitis E virus replication

Noémie Oechslin, Nathalie Da Silva, Maliki Ankavay, Darius Moradpour, Jérôme Gouttenoire

Proc Natl Acad Sci U S A. 2023 Dec 26; 120(52): e2307423120. Published online 2023 Dec 18. doi: 10.1073/pnas.2307423120

PMCID:: PMC10756275

Abstract Article PDF–7.2M

Select item 106411784.

HPIP and RUFY3 are noncanonical guanine nucleotide exchange factors of Rab5 to regulate endocytosis-coupled focal adhesion turnover

Saratchandra Singh Khumukcham, Vasudevarao Penugurti, Suresh Bugide, Anju Dwivedi, Anita Kumari, P.S. Kesavan, Sruchytha Kalali, Yasaswi Gayatri Mishra, Vakkalagadda A. Ramesh, Hampapathalu A. Nagarajaram, Aprotim Mazumder, Bramanandam Manavathi

J Biol Chem. 2023 Nov; 299(11): 105311. Published online 2023 Oct 4. doi: 10.1016/j.jbc.2023.105311

PMCID:: PMC10641178

Abstract Article PDF–4.6M

Select item 106147175.

Hepatitis B virus promotes its own replication by enhancing RAB5A-mediated dual activation of endosomal and autophagic vesicle pathways

Zhenyu Zhao, Zhen Wei, Jiaxin Zheng, Zhihong Li, Hecun Zou, Xiang Wen, Fahong Li, Xueyu Wang, Qian Huang, Huaqing Zeng, Hui Fan, Xuefei Cai, Jiming Zhang, Bei Jia, Ailong Huang, Mengji Lu, Yong Lin

Emerg Microbes Infect. 2023; 12(2): 2261556. Published online 2023 Sep 19. doi: 10.1080/22221751.2023.2261556

PMCID:: PMC10614717

Abstract Article PDF–4.7M

Select item 105859566.

Receptor-mediated internalization promotes increased endosome size and number in a RAB4- and RAB5-dependent manner

Naava Naslavsky, Steve Caplan

Eur J Cell Biol. Author manuscript; available in PMC 2023 Oct 19.

Published in final edited form as: Eur J Cell Biol. 2023 Sep; 102(3): 151339. Published online 2023 Jul 6. doi: 10.1016/j.ejcb.2023.151339

PMCID:: PMC10585956

Abstract Article PDF–941K

Select item 102374227.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 101962198.

RNA demethylase ALKBH5 promotes colorectal cancer progression by posttranscriptional activation of RAB5A in an m6A‐YTHDF2‐dependent manner

Dingcheng Shen, Jinxin Lin, Yumo Xie, Zhuokai Zhuang, Gaopo Xu, Shaoyong Peng, Guannan Tang, Liangliang Bai, Mingxuan Zhu, Yu Zhang, Ziying Huang, Puning Wang, Xiaoxia Liu, Meijin Huang, Yanxin Luo, Xiaolin Wang, Huichuan Yu

Clin Transl Med. 2023 May; 13(5): e1279. Published online 2023 May 18. doi: 10.1002/ctm2.1279

PMCID:: PMC10196219

Abstract Article PDF–3.5M

Select item 101050689.

Kai-Chen Wu, Nicholas D. Condon, Timothy A. Hill, Robert C. Reid, David P. Fairlie, Junxian Lim

J Innate Immun. 2023 Jan-Dec; 15(1): 468–484. Published online 2023 Mar 7. doi: 10.1159/000530012

PMCID:: PMC10105068

Abstract Article PDF–2.2M

Select item 994427010.

MTSS1 curtails lung adenocarcinoma immune evasion by promoting AIP4-mediated PD-L1 monoubiquitination and lysosomal degradation

Yuan Wang, Zhenchang Jia, Chenxi Liang, Yunfei He, Min Cong, Qiuyao Wu, Pu Tian, Dasa He, Xiang Miao, Beibei Sun, Yue Yin, Chao Peng, Feng Yao, Da Fu, Yajun Liang, Peiyuan Zhang, Hua Xiong, Guohong Hu

Cell Discov. 2023; 9: 20. Published online 2023 Feb 21. doi: 10.1038/s41421-022-00507-x

PMCID:: PMC9944270

Abstract Article PDF–3.2M

Select item 981601811.

ATP9A deficiency causes ADHD and aberrant endosomal recycling via modulating RAB5 and RAB11 activity

Tian Meng, Xiaoting Chen, Zhengjie He, Haofeng Huang, Shiyin Lin, Kunru Liu, Guo Bai, Hao Liu, Mindong Xu, Haixia Zhuang, Yunlong Zhang, Ahmed Waqas, Qian Liu, Chuan Zhang, Xiang-Dong Sun, Huansen Huang, Muhammad Umair, Yousheng Yan, Du Feng

Mol Psychiatry. 2023; 28(3): 1219–1231. Published online 2023 Jan 6. doi: 10.1038/s41380-022-01940-w

PMCID:: PMC9816018

Abstract Article PDF–6.6M

Select item 977255812.

HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation

Jingsheng Yuan, Tao Lv, Jian Yang, Zhenru Wu, Lvnan Yan, Jiayin Yang, Yujun Shi, Li Jiang

Cell Mol Gastroenterol Hepatol. 2023; 15(2): 307–325. Published online 2022 Oct 14. doi: 10.1016/j.jcmgh.2022.10.005

PMCID:: PMC9772558

Abstract Article PDF–8.2M

Select item 968395913.

Identification of Key Genes and miRNAs Affecting Osteosarcoma Based on Bioinformatics

Le Li, Xin Zhou, Wencan Zhang, Ran Zhao

Dis Markers. 2022; 2022: 1015593. Published online 2022 Nov 16. doi: 10.1155/2022/1015593

PMCID:: PMC9683959

Abstract Article PDF–2.1M

Select item 947545314.

The N⁶-methyladenosine-mediated lncRNA WEE2-AS1 promotes glioblastoma progression by stabilizing RPN2

Boyan Li, Rongrong Zhao, Wei Qiu, Ziwen Pan, Shulin Zhao, Yanhua Qi, Jiawei Qiu, Shouji Zhang, Qindong Guo, Yang Fan, Hao Xu, Ming Li, Gang Li, Hao Xue

Theranostics. 2022; 12(14): 6363–6379. Published online 2022 Aug 29. doi: 10.7150/thno.74600

PMCID:: PMC9475453

Abstract Article PDF–4.4M

Select item 927928515.

Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery

Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili

Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z

PMCID:: PMC9279285

Abstract Article PDF–2.5M

Select item 916548716.

RNF115 Inhibits the Post‐ER Trafficking of TLRs and TLRs‐Mediated Immune Responses by Catalyzing K11‐Linked Ubiquitination of RAB1A and RAB13

Zhi‐Dong Zhang, Hong‐Xu Li, Hu Gan, Zhen Tang, Yu‐Yao Guo, Shu‐Qi Yao, Tianzi Liuyu, Bo Zhong, Dandan Lin

Adv Sci (Weinh) 2022 Jun; 9(16): 2105391. Published online 2022 Mar 28. doi: 10.1002/advs.202105391

PMCID:: PMC9165487

Abstract Article PDF–7.5M

Select item 911973617.

OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization

Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti

Science. Author manuscript; available in PMC 2022 Sep 11.

Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983

PMCID:: PMC9119736

Abstract Article PDF–3.3M

Select item 889970118.

lncRNA HITT inhibits metastasis by attenuating Rab5-mediated endocytosis in lung adenocarcinoma

Xingwen Wang, Shanliang Zheng, Fan Yang, Wenxin Zhang, Dong Zhao, Xuting Xue, Qingyu Lin, Yunfei He, Guohong Hu, Ying Hu

Mol Ther. 2022 Mar 2; 30(3): 1071–1088. Published online 2022 Jan 8. doi: 10.1016/j.ymthe.2022.01.014

PMCID:: PMC8899701

Abstract Article PDF–6.1M

Select item 875541919.

Host E3 ligase HUWE1 attenuates the proapoptotic activity of the MERS-CoV accessory protein ORF3 by promoting its ubiquitin-dependent degradation

Yuzheng Zhou, Rong Zheng, Sixu Liu, Cyrollah Disoma, Ashuai Du, Shiqin Li, Zongpeng Chen, Zijun Dong, Yongxing Zhang, Sijia Li, Pinjia Liu, Aroona Razzaq, Xuan Chen, Yujie Liao, Siyi Tao, Yuxin Liu, Lunan Xu, Qianjun Zhang, Jian Peng, Xu Deng, Shanni Li, Taijiao Jiang, Zanxian Xia

J Biol Chem. 2022 Feb; 298(2): 101584. Published online 2022 Jan 13. doi: 10.1016/j.jbc.2022.101584

PMCID:: PMC8755419

Abstract Article PDF–3.5M

Select item 856647320.

Competitive binding of E3 ligases TRIM26 and WWP2 controls SOX2 in glioblastoma

Tatenda Mahlokozera, Bhuvic Patel, Hao Chen, Patrick Desouza, Xuan Qu, Diane D. Mao, Daniel Hafez, Wei Yang, Rukayat Taiwo, Mounica Paturu, Afshin Salehi, Amit D. Gujar, Gavin P. Dunn, Nima Mosammaparast, Allegra A. Petti, Hiroko Yano, Albert H. Kim

Nat Commun. 2021; 12: 6321. Published online 2021 Nov 3. doi: 10.1038/s41467-021-26653-6

PMCID:: PMC8566473

Abstract Article PDF–2.7M

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