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Select item 109176601.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Article PDF–4.8M

Select item 106739892.

ELABELA/APJ Axis Prevents Diabetic Glomerular Endothelial Injury by Regulating AMPK/NLRP3 Pathway

Zhida Chen, Zhe Wang, Yepeng Hu, Huangbo Lin, Li Yin, Jing Kong, Yikai Zhang, Bibi Hu, Tiekun Li, Xianan Zheng, Qiongying Yang, Shu Ye, Shengyao Wang, Qiao Zhou, Chao Zheng

Inflammation. 2023; 46(6): 2343–2358. Published online 2023 Aug 4. doi: 10.1007/s10753-023-01882-7

PMCID:: PMC10673989

Article PDF–7.8M

Select item 104787543.

CHARGE syndrome-associated CHD7 acts at ISL1-regulated enhancers to modulate second heart field gene expression

Athanasia Stathopoulou, Ping Wang, Charlotte Thellier, Robert G Kelly, Deyou Zheng, Peter J Scambler

Cardiovasc Res. 2023 Aug; 119(11): 2089–2105. Published online 2023 Apr 13. doi: 10.1093/cvr/cvad059

Correction in:: Cardiovasc Res. 2024 Jan; 120(1): 120.

PMCID:: PMC10478754

Article PDF–21M

Select item 102806934.

Exercise improves homeostasis of the intestinal epithelium by activation of apelin receptor-AMP-activated protein kinase signalling

Song Ah Chae, Min Du, Jun Seok Son, Mei-Jun Zhu

J Physiol. Author manuscript; available in PMC 2024 Jun 1.

Published in final edited form as: J Physiol. 2023 Jun; 601(12): 2371–2389. Published online 2023 May 16. doi: 10.1113/JP284552

PMCID:: PMC10280693

Article PDF–1.6M

Select item 99129825.

Cancer apelin receptor suppresses vascular mimicry in malignant melanoma

Koichi Inukai, Kazuyoshi Kise, Yumiko Hayashi, Weizhen Jia, Fumitaka Muramatsu, Naoki Okamoto, Hirotaka Konishi, Keigo Akuta, Hiroyasu Kidoya, Nobuyuki Takakura

Pathol Oncol Res. 2023; 29: 1610867. Published online 2023 Jan 27. doi: 10.3389/pore.2023.1610867

PMCID:: PMC9912982

Article PDF–2.7M

Select item 96870186.

CXCL12 defines lung endothelial heterogeneity and promotes distal vascular growth

Prashant Chandrasekaran, Nicholas M. Negretti, Aravind Sivakumar, Derek C. Liberti, Hongbo Wen, Maureen Peers de Nieuwburgh, Joanna Y. Wang, Nigel S. Michki, Fatima N. Chaudhry, Sukhmani Kaur, MinQi Lu, Annabelle Jin, Jarod A. Zepp, Lisa R. Young, Jennifer M. S. Sucre, David B. Frank

Development. 2022 Nov 1; 149(21): dev200909. Published online 2022 Oct 31. doi: 10.1242/dev.200909

PMCID:: PMC9687018

Article

Select item 96043787.

CCBE1 Is Essential for Epicardial Function during Myocardium Development

Fernando Bonet, Sabrina Brito Añez, José Manuel Inácio, Matthias E. Futschik, José Antonio Belo

Int J Mol Sci. 2022 Oct; 23(20): 12642. Published online 2022 Oct 20. doi: 10.3390/ijms232012642

PMCID:: PMC9604378

Article PDF–3.7M

Select item 90190548.

Endothelial progenitor cells stimulate neonatal lung angiogenesis through FOXF1-mediated activation of BMP9/ACVRL1 signaling

Guolun Wang, Bingqiang Wen, Zicheng Deng, Yufang Zhang, Olena A. Kolesnichenko, Vladimir Ustiyan, Arun Pradhan, Tanya V. Kalin, Vladimir V. Kalinichenko

Nat Commun. 2022; 13: 2080. Published online 2022 Apr 19. doi: 10.1038/s41467-022-29746-y

PMCID:: PMC9019054

Article PDF–6.3M

Select item 88093599.

Analysis of Placental Arteriovenous Formation Reveals New Insights Into Embryos With Congenital Heart Defects

Jacinta I. Kalisch-Smith, Emily C. Morris, Mary A. A. Strevens, Andia N. Redpath, Kostantinos Klaourakis, Dorota Szumska, Jennifer E. Outhwaite, Xin Sun, Joaquim Miguel Vieira, Nicola Smart, Sarah De Val, Paul R. Riley, Duncan B. Sparrow

Front Genet. 2021; 12: 806136. Published online 2022 Jan 19. doi: 10.3389/fgene.2021.806136

PMCID:: PMC8809359

Article PDF–3.1M

Select item 879060010.

Maternal exercise intergenerationally drives muscle-based thermogenesis via activation of apelin-AMPK signaling

Jun Seok Son, Song Ah Chae, Liang Zhao, Hongyang Wang, Jeanene M. de Avila, Mei-Jun Zhu, Zhihua Jiang, Min Du

EBioMedicine. 2022 Feb; 76: 103842. Published online 2022 Jan 23. doi: 10.1016/j.ebiom.2022.103842

PMCID:: PMC8790600

Article PDF–4.3M

Select item 859945511.

Single cell multi-omic analysis identifies a Tbx1-dependent multilineage primed population in murine cardiopharyngeal mesoderm

Hiroko Nomaru, Yang Liu, Christopher De Bono, Dario Righelli, Andrea Cirino, Wei Wang, Hansoo Song, Silvia E. Racedo, Anelisa G. Dantas, Lu Zhang, Chen-Leng Cai, Claudia Angelini, Lionel Christiaen, Robert G. Kelly, Antonio Baldini, Deyou Zheng, Bernice E. Morrow

Nat Commun. 2021; 12: 6645. Published online 2021 Nov 17. doi: 10.1038/s41467-021-26966-6

PMCID:: PMC8599455

Article PDF–9.6M

Select item 831323912.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Article PDF–1.6M

Select item 826371513.

Endothelial cell-derived Apelin inhibits tumor growth by altering immune cell localization

Liuying Hu, Yumiko Hayashi, Hiroyasu Kidoya, Nobuyuki Takakura

Sci Rep. 2021; 11: 14047. Published online 2021 Jul 7. doi: 10.1038/s41598-021-93619-5

PMCID:: PMC8263715

Article PDF–2.0M

Select item 811918414.

Delta-like 4 is required for pulmonary vascular arborization and alveolarization in the developing lung

Sheng Xia, Heather L. Menden, Nick Townley, Sherry M. Mabry, Jeffrey Johnston, Michael F. Nyp, Daniel P. Heruth, Thomas Korfhagen, Venkatesh Sampath

JCI Insight. 2021 Apr 8; 6(7): e134170. Published online 2021 Apr 8. doi: 10.1172/jci.insight.134170

PMCID:: PMC8119184

Article PDF–13M

Select item 807202515.

Modulation of APLNR Signaling Is Required during the Development and Maintenance of the Hematopoietic System

Melany Jackson, Antonella Fidanza, A. Helen Taylor, Stanislav Rybtsov, Richard Axton, Maria Kydonaki, Stephen Meek, Tom Burdon, Alexander Medvinsky, Lesley M. Forrester

Stem Cell Reports. 2021 Apr 13; 16(4): 727–740. Published online 2021 Mar 4. doi: 10.1016/j.stemcr.2021.02.003

PMCID:: PMC8072025

Article PDF–3.0M

Select item 806361616.

Histone Lysine Methyltransferase SETD2 Regulates Coronary Vascular Development in Embryonic Mouse Hearts

Fengling Chen, Jiewen Chen, Hong Wang, Huayuan Tang, Lei Huang, Shijia Wang, Xinru Wang, Xi Fang, Jie Liu, Li Li, Kunfu Ouyang, Zhen Han

Front Cell Dev Biol. 2021; 9: 651655. Published online 2021 Apr 9. doi: 10.3389/fcell.2021.651655

PMCID:: PMC8063616

Article PDF–4.0M

Select item 805252517.

Apelin/APJ relieve diabetic cardiomyopathy by reducing microvascular dysfunction

Bin Li, Jiming Yin, Jing Chang, Jia Zhang, Yangjia Wang, Haixia Huang, Wei Wang, Xiangjun Zeng

J Endocrinol. 2021 Apr; 249(1): 1–18. Published online 2021 Jan 25. doi: 10.1530/JOE-20-0398

PMCID:: PMC8052525

Article PDF–5.6M

Select item 792763818.

Aplnr knockout mice display sex-specific changes in conditioned fear

Lucas T. Laudermilk, Kathryn M. Harper, Sheryl S. Moy, Scott Runyon, Bin Zhou, Beverly Koller, Rangan Maitra

Behav Brain Res. Author manuscript; available in PMC 2022 Feb 26.

Published in final edited form as: Behav Brain Res. 2021 Feb 26; 400: 113059. Published online 2020 Dec 11. doi: 10.1016/j.bbr.2020.113059

PMCID:: PMC7927638

Article PDF–1.4M

Select item 779224419.

p53‐Mediated Repression of the PGC1A (PPARG Coactivator 1α) and APLNR (Apelin Receptor) Signaling Pathways Limits Fatty Acid Oxidation Energetics: Implications for Cardio‐oncology

Bruno Saleme, Subhash K. Das, Yongneng Zhang, Aristeidis E. Boukouris, Maria Areli Lorenzana Carrillo, Juan Jovel, Cory S. Wagg, Gary D. Lopaschuk, Evangelos D. Michelakis, Gopinath Sutendra

J Am Heart Assoc. 2020 Aug 4; 9(15): e017247. Published online 2020 Jul 29. doi: 10.1161/JAHA.120.017247

PMCID:: PMC7792244

Article PDF–1.1M

Select item 772104920.

Capillary cell type specialization in the alveolus

Astrid Gillich, Fan Zhang, Colleen G. Farmer, Kyle J. Travaglini, Serena Y. Tan, Mingxia Gu, Bin Zhou, Jeffrey A. Feinstein, Mark A. Krasnow, Ross J. Metzger

Nature. Author manuscript; available in PMC 2021 Apr 14.

Published in final edited form as: Nature. 2020 Oct; 586(7831): 785–789. Published online 2020 Oct 14. doi: 10.1038/s41586-020-2822-7

PMCID:: PMC7721049

Article PDF–9.8M

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