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Items: 1 to 20 of 39

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Endothelial PlexinD1 signaling instructs spinal cord vascularization and motor neuron development
José Ricardo Vieira, Bhavin Shah, Sebastian Dupraz, Isidora Paredes, Patricia Himmels, Géza Schermann, Heike Adler, Alessia Motta, Lea Gärtner, Ariadna Navarro-Aragall, Elena Ioannou, Elena Dyukova, Remy Bonnavion, Andreas Fischer, Dario Bonanomi, Frank Bradke, Christiana Ruhrberg, Carmen Ruiz de Almodóvar
Neuron. 2022 Dec 21; 110(24): 4074–4089.e6. doi: 10.1016/j.neuron.2022.12.005
PMCID:
PMC9796814
AbstractArticle
3.
Little skate genome provides insights into genetic programs essential for limb-based locomotion
DongAhn Yoo, Junhee Park, Chul Lee, Injun Song, Young Ho Lee, Tery Yun, Hyemin Lee, Adriana Heguy, Jae Yong Han, Jeremy S Dasen, Heebal Kim, Myungin Baek
eLife. 2022; 11: e78345. Published online 2022 Oct 26. doi: 10.7554/eLife.78345
PMCID:
PMC9605692
AbstractArticlePDF–8.4M
4.
Transcriptional dynamics of murine motor neuron maturation in vivo and in vitro
Tulsi Patel, Jennifer Hammelman, Siaresh Aziz, Sumin Jang, Michael Closser, Theodore L. Michaels, Jacob A. Blum, David K. Gifford, Hynek Wichterle
Nat Commun. 2022; 13: 5427. Published online 2022 Sep 15. doi: 10.1038/s41467-022-33022-4
PMCID:
PMC9477853
AbstractArticlePDF–7.4M
5.
Disrupted Choline Clearance and Sustained Acetylcholine Release In Vivo by a Common Choline Transporter Coding Variant Associated with Poor Attentional Control in Humans
Eryn Donovan, Cassandra Avila, Sarah Klausner, Vinay Parikh, Cristina Fenollar-Ferrer, Randy D. Blakely, Martin Sarter
J Neurosci. 2022 Apr 20; 42(16): 3426–3444. doi: 10.1523/JNEUROSCI.1334-21.2022
PMCID:
PMC9034784
AbstractArticlePDF–5.1M
6.
Control of spinal motor neuron terminal differentiation through sustained Hoxc8 gene activity
Catarina Catela, Yihan Chen, Yifei Weng, Kailong Wen, Paschalis Kratsios
eLife. 2022; 11: e70766. Published online 2022 Mar 22. doi: 10.7554/eLife.70766
PMCID:
PMC8940177
AbstractArticlePDF–6.0M
7.
A Null Mutation for the α3 Nicotinic Acetylcholine (ACh) Receptor Gene Abolishes Fast Synaptic Activity in Sympathetic Ganglia and Reveals That ACh Output from Developing Preganglionic Terminals Is Regulated in an Activity-Dependent Retrograde Manner
Siamak Rassadi, Arjun Krishnaswamy, Brigitte Pié, Russell McConnell, Michele H. Jacob, Ellis Cooper
J Neurosci. 2005 Sep 14; 25(37): 8555–8566. doi: 10.1523/JNEUROSCI.1983-05.2005
PMCID:
PMC6725660
AbstractArticlePDF–819K
8.
Mouse screen reveals multiple new genes underlying mouse and human hearing loss
Neil J. Ingham, Selina A. Pearson, Valerie E. Vancollie, Victoria Rook, Morag A. Lewis, Jing Chen, Annalisa Buniello, Elisa Martelletti, Lorenzo Preite, Chi Chung Lam, Felix D. Weiss, Zӧe Powis, Pim Suwannarat, Christopher J. Lelliott, Sally J. Dawson, Jacqueline K. White, Karen P. Steel
PLoS Biol. 2019 Apr; 17(4): e3000194. Published online 2019 Apr 11. doi: 10.1371/journal.pbio.3000194
PMCID:
PMC6459510
AbstractArticlePDF–5.1M
9.
Blocking skeletal muscle DHPRs/Ryr1 prevents neuromuscular synapse loss in mutant mice deficient in type III Neuregulin 1 (CRD-Nrg1)
Yun Liu, Yoshie Sugiura, Fujun Chen, Kuo-Fen Lee, Qiaohong Ye, Weichun Lin
PLoS Genet. 2019 Mar; 15(3): e1007857. Published online 2019 Mar 14. doi: 10.1371/journal.pgen.1007857
PMCID:
PMC6417856
AbstractArticlePDF–8.3M
10.
Genomic variants in an inbred mouse model predict mania-like behaviors
Michael C. Saul, Sharon A. Stevenson, Changjiu Zhao, Terri M. Driessen, Brian E. Eisinger, Stephen C. Gammie
PLoS One. 2018; 13(5): e0197624. Published online 2018 May 16. doi: 10.1371/journal.pone.0197624
PMCID:
PMC5955540
AbstractArticlePDF–3.1M
11.
Placentation defects are highly prevalent in embryonic lethal mouse mutants
Vicente Perez-Garcia, Elena Fineberg, Robert Wilson, Alexander Murray, Cecilia Icoresi Mazzeo, Catherine Tudor, Arnold Sienerth, Jacqueline K. White, Elizabeth Tuck, Edward J. Ryder, Diane Gleeson, Emma Siragher, Hannah Wardle-Jones, Nicole Staudt, Neha Wali, John Collins, Stefan Geyer, Elisabeth M. Busch-Nentwich, Antonella Galli, James C. Smith, Elizabeth Robertson, David J. Adams, Wolfgang J. Weninger, Timothy Mohun, Myriam Hemberger
Nature. Author manuscript; available in PMC 2018 Sep 14.
Published in final edited form as: Nature. 2018 Mar 22; 555(7697): 463–468. Published online 2018 Mar 14. doi: 10.1038/nature26002
PMCID:
PMC5866719
AbstractArticlePDF–7.4M
12.
A staging system for correct phenotype interpretation of mouse embryos harvested on embryonic day 14 (E14.5)
Stefan H. Geyer, Lukas Reissig, Julia Rose, Robert Wilson, Fabrice Prin, Dorota Szumska, Ramiro Ramirez‐Solis, Catherine Tudor, Jacqui White, Timothy J. Mohun, Wolfgang J. Weninger
J Anat. 2017 May; 230(5): 710–719. Published online 2017 Feb 9. doi: 10.1111/joa.12590
PMCID:
PMC5382591
AbstractArticlePDF–1.5M
13.
Highly variable penetrance of abnormal phenotypes in embryonic lethal knockout mice
Robert Wilson, Stefan H. Geyer, Lukas Reissig, Julia Rose, Dorota Szumska, Emily Hardman, Fabrice Prin, Christina McGuire, Ramiro Ramirez-Solis, Jacqui White, Antonella Galli, Catherine Tudor, Elizabeth Tuck, Cecilia Icoresi Mazzeo, James C. Smith, Elizabeth Robertson, David J. Adams, Timothy Mohun, Wolfgang J. Weninger
Version 2. Wellcome Open Res. 2016; 1: 1. Published online 2017 Feb 27. doi: 10.12688/wellcomeopenres.9899.2
PMCID:
PMC5159622
AbstractArticlePDF–7.4M
14.
Differential Impact of Genetically Modulated Choline Transporter Expression on the Release of Endogenous Versus Newly Synthesized Acetylcholine
Hideki Iwamoto, M. Wade Calcutt, Randy D. Blakely
Neurochem Int. Author manuscript; available in PMC 2017 Sep 1.
Published in final edited form as: Neurochem Int. 2016 Sep; 98: 138–145. Published online 2016 Mar 22. doi: 10.1016/j.neuint.2016.03.012
PMCID:
PMC4969175
AbstractArticlePDF–543K
15.
The interaction between maternal immune activation and alpha 7 nicotinic acetylcholine receptor in regulating behaviors in the offspring
Wei-Li Wu, Catherine E. Adams, Karen E. Stevens, Ke-Huan Chow, Robert Freedman, Paul H. Patterson
Brain Behav Immun. Author manuscript; available in PMC 2016 May 1.
Published in final edited form as: Brain Behav Immun. 2015 May; 46: 192–202. Published online 2015 Feb 12. doi: 10.1016/j.bbi.2015.02.005
PMCID:
PMC4414803
AbstractArticlePDF–2.2M
16.
Choline Transporter Hemizygosity Results in Diminished Basal Extracellular Dopamine Levels in Nucleus Accumbens and Blunts Dopamine Elevations Following Cocaine or Nicotine
Yu Dong, John A. Dani, Randy D. Blakely
Biochem Pharmacol. Author manuscript; available in PMC 2015 Apr 29.
Published in final edited form as: Biochem Pharmacol. 2013 Oct 15; 86(8): 1084–1088. Published online 2013 Aug 9. doi: 10.1016/j.bcp.2013.07.019
PMCID:
PMC4413453
AbstractArticlePDF–302K
17.
Resistance to Noise-Induced Hearing Loss in 129S6 and MOLF Mice: Identification of Independent, Overlapping, and Interacting Chromosomal Regions
Valerie A. Street, Sharon G. Kujawa, Ani Manichaikul, Karl W. Broman, Jeremy C. Kallman, Dustin J. Shilling, Ayaka J. Iwata, Linda C. Robinson, Carol A. Robbins, Jin Li, M. Charles Liberman, Bruce L Tempel
J Assoc Res Otolaryngol. 2014 Oct; 15(5): 721–738. Published online 2014 Jun 21. doi: 10.1007/s10162-014-0472-x
PMCID:
PMC4164691
AbstractArticlePDF–2.8M
18.
Transgenic overexpression of the presynaptic choline transporter elevates acetylcholine levels and augments motor endurance
Ericka C. Holmstrand, David Lund, Ajeesh Koshy Cherian, Jane Wright, Rolicia F. Martin, Elizabeth A. Ennis, Gregg D. Stanwood, Martin Sarter, Randy D. Blakely
Neurochem Int. Author manuscript; available in PMC 2014 Jul 21.
Published in final edited form as: Neurochem Int. 2014 Jul; 73: 217–228. Published online 2013 Nov 22. doi: 10.1016/j.neuint.2013.11.008
PMCID:
PMC4104494
AbstractArticlePDF–5.0M
19.
Isl1 Directly Controls a Cholinergic Neuronal Identity in the Developing Forebrain and Spinal Cord by Forming Cell Type-Specific Complexes
Hyong-Ho Cho, Francesca Cargnin, Yujin Kim, Bora Lee, Ryuk-Jun Kwon, Heejin Nam, Rongkun Shen, Anthony P. Barnes, Jae W. Lee, Seunghee Lee, Soo-Kyung Lee
PLoS Genet. 2014 Apr; 10(4): e1004280. Published online 2014 Apr 24. doi: 10.1371/journal.pgen.1004280
PMCID:
PMC3998908
AbstractArticlePDF–4.7M
20.
Monitoring cholinergic activity during attentional performance in mice heterozygous for the choline transporter: a model of cholinergic capacity limits
Giovanna Paolone, Caitlin S. Mallory, Ajeesh Koshy Cherian, Thomas R. Miller, Randy D. Blakely, Martin Sarter
Neuropharmacology. Author manuscript; available in PMC 2014 Dec 1.
Published in final edited form as: Neuropharmacology. 2013 Dec; 0: 10.1016/j.neuropharm.2013.07.032. Published online 2013 Aug 16. doi: 10.1016/j.neuropharm.2013.07.032
PMCID:
PMC3865115
AbstractArticlePDF–2.1M

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