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Select item 114339891.

p38α Mitogen-Activated Protein Kinase—An Emerging Drug Target for the Treatment of Alzheimer’s Disease

Jan Detka, Natalia Płachtij, Martyna Strzelec, Aleksandra Manik, Kinga Sałat

Molecules. 2024 Sep; 29(18): 4354. Published online 2024 Sep 13. doi: 10.3390/molecules29184354

PMCID:: PMC11433989

Abstract Article PDF–1.8M

Select item 112399172.

Anadenanthera colubrina regulated LPS-induced inflammation by suppressing NF-κB and p38-MAPK signaling pathways

Carolina Medeiros de Almeida Maia, Priscilla Guimarães Silva Vasconcelos, Silvana Pasetto, Walton Colby Godwin, Joanda Paolla Raimundo e Silva, Josean Fechine Tavares, Vanessa Pardi, Edja Maria Melo de Brito Costa, Ramiro Mendonça Murata

Sci Rep. 2024; 14: 16028. Published online 2024 Jul 11. doi: 10.1038/s41598-024-66590-0

PMCID:: PMC11239917

Abstract Article PDF–2.2M

Select item 112099353.

Antagonistic roles of canonical and alternative-RPA in disease-associated tandem CAG repeat instability

Terence Gall-Duncan, Jennifer Luo, Carla-Marie Jurkovic, Laura A. Fischer, Kyota Fujita, Amit L. Deshmukh, Rachel J. Harding, Stephanie Tran, Mustafa Mehkary, Vanessa Li, David E. Leib, Ran Chen, Hikari Tanaka, Amanda G. Mason, Dominique Lévesque, Mahreen Khan, Mortezaali Razzaghi, Tanya Prasolava, Stella Lanni, Nozomu Sato, Marie-Christine Caron, Gagan B. Panigrahi, Peixiang Wang, Rachel Lau, Arturo López Castel, Jean-Yves Masson, Lynette Tippett, Clinton Turner, Maria Spies, Albert R. La Spada, Eric I. Campos, Maurice A. Curtis, François-Michel Boisvert, Richard L.M. Faull, Beverly L. Davidson, Masayuki Nakamori, Hitoshi Okazawa, Marc S. Wold, Christopher E. Pearson

Cell. Author manuscript; available in PMC 2024 Oct 26.

Published in final edited form as: Cell. 2023 Oct 26; 186(22): 4898–4919.e25. Published online 2023 Oct 11. doi: 10.1016/j.cell.2023.09.008

PMCID:: PMC11209935

Abstract Article PDF–3.0M

Select item 111693594.

Lack of p38 activation in T cells increases IL-35 and protects against obesity by promoting thermogenesis

Ivana Nikolic, Irene Ruiz-Garrido, María Crespo, Rafael Romero-Becerra, Luis Leiva-Vega, Alfonso Mora, Marta León, Elena Rodríguez, Magdalena Leiva, Ana Belén Plata-Gómez, Maria Beatriz Alvarez Flores, Jorge L Torres, Lourdes Hernández-Cosido, Juan Antonio López, Jesús Vázquez, Alejo Efeyan, Pilar Martin, Miguel Marcos, Guadalupe Sabio

EMBO Rep. 2024 Jun; 25(6): 2635–2661. Published online 2024 May 10. doi: 10.1038/s44319-024-00149-y

PMCID:: PMC11169359

Abstract Article PDF–2.1M

Select item 111458635.

Involvement of RAMP1/p38MAPK signaling pathway in osteoblast differentiation in response to mechanical stimulation: a preliminary study

Thunwa Binlateh, Chidchanok Leethanakul, Peungchaleoy Thammanichanon

J Orthop Surg Res. 2024; 19: 330. Published online 2024 Jun 2. doi: 10.1186/s13018-024-04805-w

Correction in:: J Orthop Surg Res. 2024; 19: 399.

PMCID:: PMC11145863

Abstract Article PDF–4.2M

Select item 111317606.

CCDC134, a novel secretory protein, inhibits activation of ERK and JNK, but not p38 MAPK

J. Huang, T. Shi, T. Ma, Y. Zhang, X. Ma, Y. Lu, Q. Song, W. Liu, D. Ma, X. Qiu

Cell Mol Life Sci. 2008 Jan; 65(2): 338–349. Published online 2007 Dec 18. doi: 10.1007/s00018-007-7448-5

PMCID:: PMC11131760

Abstract Article PDF–2.1M

Select item 111094837.

K48- and K63-linked ubiquitin chain interactome reveals branch- and length-specific ubiquitin interactors

Anita Waltho, Oliver Popp, Christopher Lenz, Lukas Pluska, Mahil Lambert, Volker Dötsch, Philipp Mertins, Thomas Sommer

Life Sci Alliance. 2024 Aug; 7(8): e202402740. Published online 2024 May 21. doi: 10.26508/lsa.202402740

PMCID:: PMC11109483

Abstract Article PDF–2.9M

Select item 110460178.

YKL40 potentially via activating the P38 pathway in decreasing atherosclerotic plaque stability

Chao Wang, Yandong Liu, Wei Huan, Jianjin Wu, Jie Jin, Sili Zou, Yu Chen, Lefeng Qu

Chin Med J (Engl) 2024 Apr 20; 137(8): 1003–1005. Published online 2024 Mar 26. doi: 10.1097/CM9.0000000000003038

PMCID:: PMC11046017

Article PDF–1.8M

Select item 108937419.

Crosstalk with renal proximal tubule cells drives acidosis-induced inflammatory response and dedifferentiation of fibroblasts via p38-singaling

Marie-Christin Schulz, Michael Kopf, Michael Gekle

Cell Commun Signal. 2024; 22: 148. Published online 2024 Feb 24. doi: 10.1186/s12964-024-01527-8

PMCID:: PMC10893741

Abstract Article PDF–3.6M

Select item 1077068710.

Association of Promoter Methylation Patterns with Expression of MAPK14 in Tissue of Papillary Thyroid Cancer Patients

Maryam Shahdust, Habib Zarredar, Milad Asadi, Ayse Caner, Mahshid Dehghan, Zahra Soleimani, Farshad Seyednejad, Mortaza Raeisi

Asian Pac J Cancer Prev. 2023; 24(10): 2509–3515. doi: 10.31557/APJCP.2023.24.10.3509

PMCID:: PMC10770687

Abstract Article PDF–1.1M

Select item 1064353211.

The lncRNA MEG3/miRNA-21/P38MAPK axis inhibits coxsackievirus 3 replication in acute viral myocarditis

Feng He, Zhuo Liu, Miao Feng, Zonghui Xiao, Xiaoyu Yi, Jianxin Wu, Zhewei Liu, Gaoyu Wang, Le Li, Hailan Yao

Virus Res. 2024 Jan 2; 339: 199250. Published online 2023 Nov 1. doi: 10.1016/j.virusres.2023.199250

PMCID:: PMC10643532

Abstract Article PDF–4.2M

Select item 1058288712.

C-reactive protein impairs immune response of CD8⁺ T cells via FcγRIIb-p38MAPK-ROS axis in multiple myeloma

Jinxing Jiang, Ziyi Peng, Junying Wang, Mengping Chen, Yike Wan, Honghui Huang, Zhiqiang Liu, Jingya Wang, Jian Hou

J Immunother Cancer. 2023; 11(10): e007593. Published online 2023 Oct 15. doi: 10.1136/jitc-2023-007593

Correction in:: J Immunother Cancer. 2023; 11(12): e007593corr1.

PMCID:: PMC10582887

Abstract Article PDF–5.1M

Select item 1052468113.

LPS-Induced Inflammation Potentiates Dental Pulp Stem Cell Odontogenic Differentiation Through C5aR and p38

Ji-Hyun Kim, Muhammad Irfan, Md Akil Hossain, Susie Shin, Anne George, Seung Chung

Connect Tissue Res. Author manuscript; available in PMC 2024 Sep 1.

Published in final edited form as: Connect Tissue Res. 2023 Sep; 64(5): 505–515. Published online 2023 May 29. doi: 10.1080/03008207.2023.2218944

PMCID:: PMC10524681

Abstract Article PDF–2.1M

Select item 1023742214.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 1009133915.

P38 MAPK activated ADAM17 mediates ACE2 shedding and promotes cardiac remodeling and heart failure after myocardial infarction

Qi Chen, Yilan Li, Bike Bie, Bin Zhao, Yanxiu Zhang, Shaohong Fang, Shuijie Li, Yao Zhang

Cell Commun Signal. 2023; 21: 73. Published online 2023 Apr 12. doi: 10.1186/s12964-023-01087-3

PMCID:: PMC10091339

Abstract Article PDF–12M

Select item 1007290616.

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity

Martin Golkowski, Andrea Lius, Tanmay Sapre, Ho-Tak Lau, Taylor Moreno, Dustin J. Maly, Shao-En Ong

Mol Cell. Author manuscript; available in PMC 2023 Apr 4.

Published in final edited form as: Mol Cell. 2023 Mar 2; 83(5): 803–818.e8. Published online 2023 Feb 2. doi: 10.1016/j.molcel.2023.01.015

PMCID:: PMC10072906

Abstract Article PDF–4.2M

Select item 998331817.

Hsa‐miR‐409‐3p regulates endothelial progenitor senescence via PP2A‐P38 and is a potential ageing marker in humans

Yi‐Nan Lee, Yih‐Jer Wu, Hsin‐I Lee, Hsueh‐Hsiao Wang, Chung‐Lieh Hung, Chiung‐Yin Chang, Yen‐Hung Chou, Ting‐Yi Tien, Chun‐Wei Lee, Chao‐Feng Lin, Cheng‐Huang Su, Hung‐I Yeh

J Cell Mol Med. 2023 Mar; 27(5): 687–700. Published online 2023 Feb 9. doi: 10.1111/jcmm.17691

PMCID:: PMC9983318

Abstract Article PDF–3.8M

Select item 977165618.

Overexpression of microRNA-211 in Functional Dyspepsia via Downregulation of the Glial Cell Line-Derived Neurotrophic Factor (GDNF) by Increasing Phosphorylation of p38 MAPK Pathway

Jue Wang, Sai Gu, Bo Qin

Can J Gastroenterol Hepatol. 2022; 2022: 9394381. Published online 2022 Dec 14. doi: 10.1155/2022/9394381

PMCID:: PMC9771656

Abstract Article PDF–1.4M

Select item 974985119.

Defective synaptic plasticity in a model of Coffin–Lowry syndrome is rescued by simultaneously targeting PKA and MAPK pathways

Rong-Yu Liu, Yili Zhang, Paul Smolen, Leonard J. Cleary, John H. Byrne

Learn Mem. 2022 Dec; 29(12): 435–446. Published online 2022 Dec. doi: 10.1101/lm.053625.122

PMCID:: PMC9749851

Abstract Article PDF–3.8M

Select item 962336820.

P38 kinases mediate NLRP1 inflammasome activation after ribotoxic stress response and virus infection

Lea-Marie Jenster, Karl-Elmar Lange, Sabine Normann, Anja vom Hemdt, Jennifer D. Wuerth, Lisa D.J. Schiffelers, Yonas M. Tesfamariam, Florian N. Gohr, Laura Klein, Ines H. Kaltheuner, Stefan Ebner, Dorothee J. Lapp, Jacob Mayer, Jonas Moecking, Hidde L. Ploegh, Eicke Latz, Felix Meissner, Matthias Geyer, Beate M. Kümmerer, Florian I. Schmidt

J Exp Med. 2023 Jan 2; 220(1): e20220837. Published online 2022 Oct 31. doi: 10.1084/jem.20220837

PMCID:: PMC9623368

Abstract Article PDF–8.2M

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