U.S. flag

An official website of the United States government

Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Links from GEO Profiles

Items: 1 to 20 of 26

1.
Physical basis for distinct basal and mechanically-gated activity of the human K+ channel TRAAK
Robert A. Rietmeijer, Ben Sorum, Baobin Li, Stephen G. Brohawn
Neuron. Author manuscript; available in PMC 2022 Sep 15.
Published in final edited form as: Neuron. 2021 Sep 15; 109(18): 2902–2913.e4. Published online 2021 Aug 13. doi: 10.1016/j.neuron.2021.07.009
PMCID:
PMC8448962
AbstractArticlePDF–1.2M
2.
Syndromic disorders caused by gain-of-function variants in KCNH1, KCNK4, and KCNN3—a subgroup of K+ channelopathies
Karen W. Gripp, Sarah F. Smithson, Ingrid J. Scurr, Julia Baptista, Anirban Majumdar, Germaine Pierre, Maggie Williams, Lindsay B. Henderson, Ingrid M. Wentzensen, Heather McLaughlin, Lisette Leeuwen, Marleen E. H. Simon, Ellen van Binsbergen, Mary Beth P. Dinulos, Julie D. Kaplan, Anne McRae, Andrea Superti-Furga, Jean-Marc Good, Kerstin Kutsche
Eur J Hum Genet. 2021 Sep; 29(9): 1384–1395. Published online 2021 Feb 16. doi: 10.1038/s41431-021-00818-9
PMCID:
PMC8440610
AbstractArticlePDF–1.8M
3.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
4.
Selective regulation of human TRAAK channels by biologically active phospholipids
Samantha Schrecke, Yun Zhu, Jacob McCabe, Mariah Bartz, Charles Packianathan, Minglei Zhao, Ming Zhou, David Russell, Arthur Laganowsky
Nat Chem Biol. Author manuscript; available in PMC 2021 Mar 28.
Published in final edited form as: Nat Chem Biol. 2021 Jan; 17(1): 89–95. Published online 2020 Sep 28. doi: 10.1038/s41589-020-00659-5
PMCID:
PMC7746637
AbstractArticlePDF–1.8M
5.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
6.
Mutations in KCNK4 that Affect Gating Cause a Recognizable Neurodevelopmental Syndrome
Christiane K. Bauer, Paolo Calligari, Francesca Clementina Radio, Viviana Caputo, Maria Lisa Dentici, Nadia Falah, Frances High, Francesca Pantaleoni, Sabina Barresi, Andrea Ciolfi, Simone Pizzi, Alessandro Bruselles, Richard Person, Sarah Richards, Megan T. Cho, Daniela J. Claps Sepulveda, Stefano Pro, Roberta Battini, Giuseppe Zampino, Maria Cristina Digilio, Gianfranco Bocchinfuso, Bruno Dallapiccola, Lorenzo Stella, Marco Tartaglia
Am J Hum Genet. 2018 Oct 4; 103(4): 621–630. Published online 2018 Oct 4. doi: 10.1016/j.ajhg.2018.09.001
PMCID:
PMC6174320
AbstractArticlePDF–2.1M
7.
Functional mutagenesis screens reveal the ‘cap structure’ formation in disulfide-bridge free TASK channels
Matthias Goldstein, Susanne Rinné, Aytug K. Kiper, David Ramírez, Michael F. Netter, Daniel Bustos, Beatriz Ortiz-Bonnin, Wendy González, Niels Decher
Sci Rep. 2016; 6: 19492. Published online 2016 Jan 22. doi: 10.1038/srep19492
PMCID:
PMC4726246
AbstractArticlePDF–2.2M
8.
Racial variation in breast tumor promoter methylation in the Carolina Breast Cancer Study
Kathleen Conway, Sharon N. Edmiston, Chiu-Kit Tse, Christopher Bryant, Pei Fen Kuan, Brionna Y. Hair, Eloise A. Parrish, Ryan May, Theresa Swift-Scanlan
Cancer Epidemiol Biomarkers Prev. Author manuscript; available in PMC 2016 Jun 1.
Published in final edited form as: Cancer Epidemiol Biomarkers Prev. 2015 Jun; 24(6): 921–930. Published online 2015 Mar 25. doi: 10.1158/1055-9965.EPI-14-1228
PMCID:
PMC4452445
AbstractArticlePDF–844K
9.
Transmembrane Helix Straightening and Buckling Underlies Activation of Mechanosensitive and Thermosensitive K2P Channels
Marco Lolicato, Paul M. Riegelhaupt, Cristina Arrigoni, Kimberly A. Clark, Daniel L. Minor, Jr.
Neuron. Author manuscript; available in PMC 2015 Dec 17.
Published in final edited form as: Neuron. 2014 Dec 17; 84(6): 1198–1212. Published online 2014 Dec 11. doi: 10.1016/j.neuron.2014.11.017
PMCID:
PMC4270892
AbstractArticlePDF–1.9M
10.
Mechanosensitivity is mediated directly by the lipid membrane in TRAAK and TREK1 K+ channels
Stephen G. Brohawn, Zhenwei Su, Roderick MacKinnon
Proc Natl Acad Sci U S A. 2014 Mar 4; 111(9): 3614–3619. Published online 2014 Feb 18. doi: 10.1073/pnas.1320768111
PMCID:
PMC3948252
AbstractArticlePDF–2.0M
11.
Domain-swapped chain connectivity and gated membrane access in a Fab-mediated crystal of the human TRAAK K+ channel
Stephen G. Brohawn, Ernest B. Campbell, Roderick MacKinnon
Proc Natl Acad Sci U S A. 2013 Feb 5; 110(6): 2129–2134. Published online 2013 Jan 22. doi: 10.1073/pnas.1218950110
PMCID:
PMC3568379
AbstractArticlePDF–1.2M
12.
Crystal structure of the human K2P TRAAK, a lipid- and mechano-sensitive K+ ion channel
Stephen G. Brohawn, Josefina del Mármol, Roderick MacKinnon
Science. Author manuscript; available in PMC 2012 Apr 18.
Published in final edited form as: Science. 2012 Jan 27; 335(6067): 436–441. doi: 10.1126/science.1213808
PMCID:
PMC3329120
AbstractArticlePDF–8.2M
13.
Toward an understanding of the protein interaction network of the human liver
Jian Wang, Keke Huo, Lixin Ma, Liujun Tang, Dong Li, Xiaobi Huang, Yanzhi Yuan, Chunhua Li, Wei Wang, Wei Guan, Hui Chen, Chaozhi Jin, Junchen Wei, Wanqiao Zhang, Yongsheng Yang, Qiongming Liu, Ying Zhou, Cuili Zhang, Zhihao Wu, Wangxiang Xu, Ying Zhang, Tao Liu, Donghui Yu, Yaping Zhang, Liang Chen, Dewu Zhu, Xing Zhong, Lixin Kang, Xiang Gan, Xiaolan Yu, Qi Ma, Jing Yan, Li Zhou, Zhongyang Liu, Yunping Zhu, Tao Zhou, Fuchu He, Xiaoming Yang
Mol Syst Biol. 2011; 7: 536. Published online 2011 Oct 11. doi: 10.1038/msb.2011.67
Correction in:
Mol Syst Biol. 2017 Dec; 13(12): 965.
PMCID:
PMC3261708
AbstractArticlePDF–2.0M
14.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
15.
Variation at the NFATC2 Locus Increases the Risk of Thiazolidinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study
Swneke D. Bailey, Changchun Xie, Ron Do, Alexandre Montpetit, Rafael Diaz, Viswanathan Mohan, Bernard Keavney, Salim Yusuf, Hertzel C. Gerstein, James C. Engert, Sonia Anand, on behalf of the DREAM investigators
Diabetes Care. 2010 Oct; 33(10): 2250–2253. Published online 2010 Jul 13. doi: 10.2337/dc10-0452
PMCID:
PMC2945168
AbstractArticlePDF–153K
16.
Expression of Stretch-Activated Two-Pore Potassium Channels in Human Myometrium in Pregnancy and Labor
Iain L. O. Buxton, Cherie A. Singer, Jennifer N. Tichenor
PLoS One. 2010; 5(8): e12372. Published online 2010 Aug 25. doi: 10.1371/journal.pone.0012372
PMCID:
PMC2928262
AbstractArticlePDF–490K
17.
Gene-centric Association Signals for Lipids and Apolipoproteins Identified via the HumanCVD BeadChip
Philippa J. Talmud, Fotios Drenos, Sonia Shah, Tina Shah, Jutta Palmen, Claudio Verzilli, Tom R. Gaunt, Jacky Pallas, Ruth Lovering, Kawah Li, Juan Pablo Casas, Reecha Sofat, Meena Kumari, Santiago Rodriguez, Toby Johnson, Stephen J. Newhouse, Anna Dominiczak, Nilesh J. Samani, Mark Caulfield, Peter Sever, Alice Stanton, Denis C. Shields, on behalf of the ASCOT investigators, Sandosh Padmanabhan, Olle Melander, Claire Hastie, Christian Delles, on behalf of the NORDIL investigators, Shah Ebrahim, Michael G. Marmot, George Davey Smith, Debbie A. Lawlor, Patricia B. Munroe, for the BRIGHT Consortium, Ian N. Day, Mika Kivimaki, John Whittaker, Steve E. Humphries, Aroon D. Hingorani
Am J Hum Genet. 2009 Nov 13; 85(5): 628–642. doi: 10.1016/j.ajhg.2009.10.014
PMCID:
PMC2775832
AbstractArticlePDF–2.8M
18.
Regulation of two-pore-domain (K2P) potassium leak channels by the tyrosine kinase inhibitor genistein
J Gierten, E Ficker, R Bloehs, K Schlömer, S Kathöfer, E Scholz, E Zitron, C Kiesecker, A Bauer, R Becker, H A Katus, C A Karle, D Thomas
Br J Pharmacol. 2008 Aug; 154(8): 1680–1690. Published online 2008 Jun 2. doi: 10.1038/bjp.2008.213
PMCID:
PMC2518462
AbstractArticlePDF–347K
19.
Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes
Kouichi Kimura, Ai Wakamatsu, Yutaka Suzuki, Toshio Ota, Tetsuo Nishikawa, Riu Yamashita, Jun-ichi Yamamoto, Mitsuo Sekine, Katsuki Tsuritani, Hiroyuki Wakaguri, Shizuko Ishii, Tomoyasu Sugiyama, Kaoru Saito, Yuko Isono, Ryotaro Irie, Norihiro Kushida, Takahiro Yoneyama, Rie Otsuka, Katsuhiro Kanda, Takahide Yokoi, Hiroshi Kondo, Masako Wagatsuma, Katsuji Murakawa, Shinichi Ishida, Tadashi Ishibashi, Asako Takahashi-Fujii, Tomoo Tanase, Keiichi Nagai, Hisashi Kikuchi, Kenta Nakai, Takao Isogai, Sumio Sugano
Genome Res. 2006 Jan; 16(1): 55–65. doi: 10.1101/gr.4039406
PMCID:
PMC1356129
AbstractArticlePDF–438K
20.
The LIFEdb database in 2006
Alexander Mehrle, Heiko Rosenfelder, Ingo Schupp, Coral del Val, Dorit Arlt, Florian Hahne, Stephanie Bechtel, Jeremy Simpson, Oliver Hofmann, Winston Hide, Karl-Heinz Glatting, Wolfgang Huber, Rainer Pepperkok, Annemarie Poustka, Stefan Wiemann
Nucleic Acids Res. 2006 Jan 1; 34(Database issue): D415–D418. Published online 2005 Dec 28. doi: 10.1093/nar/gkj139
PMCID:
PMC1347501
AbstractArticlePDF–301K

Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

Filter your results:

Find related data

Recent activity

You are here: NCBI > Literature > PubMed Central (PMC)
Support Center