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Items: 1 to 20 of 95

1.
Mitochondrial Raf1 Regulates Glutamine Catabolism
Ronald L. Shanderson, Ian D. Ferguson, Zurab Siprashvili, Luca Ducoli, Albert M. Li, Weili Miao, Suhas Srinivasan, Mary Grace Velasco, Yang Li, Jiangbin Ye, Paul A. Khavari
Version 1. bioRxiv. Preprint. 2024 Mar 9. doi: 10.1101/2024.03.08.581297
PMCID:
PMC10942467
AbstractArticlePDF–6.5M
2.
circ_0029463 promotes osteoclast differentiation by mediating miR-134-5p/Rab27a axis
Lian Tang, Lin Yuan, Jiyuan Yan, Jianhua Ge, Zhi Lian, Zhong Li
J Orthop Surg Res. 2024; 19: 128. Published online 2024 Feb 7. doi: 10.1186/s13018-024-04610-5
PMCID:
PMC10851473
AbstractArticlePDF–5.5M
3.
Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis
Robert S. Kiss, Jarred Chicoine, Youssef Khalil, Robert Sladek, He Chen, Alessandro Pisaturo, Cyril Martin, Jessica D. Dale, Tegan A. Brudenell, Archith Kamath, Jeffrey Kyei-Boahen, Anouar Hafiane, Girija Daliah, Célia Alecki, Tayah S. Hopes, Martin Heier, Irene A. Aligianis, Jean-Jacques Lebrun, Julie Aspden, Emanuele Paci, Anja Kerksiek, Dieter Lütjohann, Peter Clayton, Jimi C. Wills, Alex von Kriegsheim, Tommy Nilsson, Eamonn Sheridan, Mark T. Handley
J Biol Chem. 2023 Nov; 299(11): 105295. Published online 2023 Sep 28. doi: 10.1016/j.jbc.2023.105295
PMCID:
PMC10641524
AbstractArticlePDF–3.8M
4.
Overexpression of RAB27A in Oral Squamous Cell Carcinoma Promotes Tumor Migration and Invasion via Modulation of EGFR Membrane Stability
Jue Huang, Jie-Gang Yang, Jian-Gang Ren, Hou-Fu Xia, Gao-Hong Chen, Qiu-Yun Fu, Lin-Zhou Zhang, Hai-Ming Liu, Kui-Ming Wang, Qi-Hui Xie, Gang Chen
Int J Mol Sci. 2023 Sep; 24(17): 13103. Published online 2023 Aug 23. doi: 10.3390/ijms241713103
PMCID:
PMC10488256
AbstractArticlePDF–7.8M
5.
SMC3 epigenetic silencing regulates Rab27a expression and drives pancreatic cancer progression
Nuno Bastos, Stéphanie A. Castaldo, Bárbara Adem, José C. Machado, Carlos A. Melo, Sonia A. Melo
J Transl Med. 2023; 21: 578. Published online 2023 Aug 28. doi: 10.1186/s12967-023-04448-1
PMCID:
PMC10463307
AbstractArticlePDF–1.8M
6.
A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2–Bispecific Antibody for Combination Cancer Therapy
Amr El Zawily, Frederick S. Vizeacoumar, Renuka Dahiya, Sara L. Banerjee, Kalpana K. Bhanumathy, Hussain Elhasasna, Glinton Hanover, Jessica C. Sharpe, Malkon G. Sanchez, Paul Greidanus, R. Greg Stacey, Kyung-Mee Moon, Ilya Alexandrov, Juha P. Himanen, Dimitar B. Nikolov, Humphrey Fonge, Aaron P. White, Leonard J. Foster, Bingcheng Wang, Behzad M. Toosi, Nicolas Bisson, Tajib A. Mirzabekov, Franco J. Vizeacoumar, Andrew Freywald
Clin Cancer Res. 2023 Jul 14; 29(14): 2686–2701. Published online 2023 Mar 28. doi: 10.1158/1078-0432.CCR-22-2535
PMCID:
PMC10345963
AbstractArticlePDF–13M
7.
Immunodeficiency with susceptibility to lymphoma with complex genotype affecting energy metabolism (FBP1, ACAD9) and vesicle trafficking (RAB27A)
Nina Brauer, Yuto Maruta, Miriam Lisci, Katharina Strege, Ilske Oschlies, Hikari Nakamura, Svea Böhm, Kai Lehmberg, Leon Brandhoff, Stephan Ehl, Nima Parvaneh, Wolfram Klapper, Mitsunori Fukuda, Gillian M. Griffiths, Hans Christian Hennies, Tim Niehues, Sandra Ammann
Front Immunol. 2023; 14: 1151166. Published online 2023 Jun 14. doi: 10.3389/fimmu.2023.1151166
PMCID:
PMC10303925
AbstractArticlePDF–24M
8.
Rab27a-mediated extracellular vesicle secretion contributes to osteogenesis in periodontal ligament-bone niche communication
Yun Lu, Liru Zhao, Jiaqi Mao, Wen Liu, Wensheng Ma, Bingjiao Zhao
Sci Rep. 2023; 13: 8479. Published online 2023 May 25. doi: 10.1038/s41598-023-35172-x
PMCID:
PMC10213006
AbstractArticlePDF–3.0M
9.
抑制RAB27a能够抑制三阴乳腺癌细胞的增殖、侵袭和粘附
王 丽, 严 志锐, 夏 耀雄
Nan Fang Yi Ke Da Xue Xue Bao. 2023 Apr 20; 43(4): 560–567. Chinese. doi: 10.12122/j.issn.1673-4254.2023.04.08
PMCID:
PMC10202786
AbstractArticlePDF–2.0M
10.
Expression and significant roles of the lncRNA NEAT1/miR‐493‐5p/Rab27A axis in ulcerative colitis
Hecheng Wang, Jiadan Teng, Mingtao Wang, Yuhang Zhang, Xiaoshuang Liu, Zhuya Liu
Immun Inflamm Dis. 2023 May; 11(5): e814. Published online 2023 May 16. doi: 10.1002/iid3.814
PMCID:
PMC10187010
AbstractArticlePDF–2.2M
11.
Novel RAB27A Variant Associated with Late-Onset Hemophagocytic Lymphohistiocytosis Alters Effector Protein Binding
Timo C. E. Zondag, Lamberto Torralba-Raga, Jan A. M. Van Laar, Maud A. W. Hermans, Arjen Bouman, Iris H. I. M. Hollink, P. Martin Van Hagen, Deborah A. Briggs, Alistair N. Hume, Yenan T. Bryceson
J Clin Immunol. 2022; 42(8): 1685–1695. Published online 2022 Jul 23. doi: 10.1007/s10875-022-01315-4
PMCID:
PMC9700621
AbstractArticlePDF–1023K
12.
RAB27A promotes the proliferation and invasion of colorectal cancer cells
Qingyan Li, Huixia Zhao, Weiwei Dong, Na Guan, Yanyan Hu, Zhiyan Zeng, He Zhang, Fengyun Zhang, Qiuwen Li, Jingwen Yang, Wenhua Xiao
Sci Rep. 2022; 12: 19359. Published online 2022 Nov 12. doi: 10.1038/s41598-022-23696-7
Correction in:
Sci Rep. 2023; 13: 734.
PMCID:
PMC9653419
AbstractArticlePDF–2.0M
13.
PRR34-AS1 promotes exosome secretion of VEGF and TGF-β via recruiting DDX3X to stabilize Rab27a mRNA in hepatocellular carcinoma
Zhilei Zhang, Ye Zhou, Yuming Jia, Chao Wang, Meng Zhang, Zhuo Xu
J Transl Med. 2022; 20: 491. Published online 2022 Oct 27. doi: 10.1186/s12967-022-03628-9
PMCID:
PMC9615160
AbstractArticlePDF–8.3M
14.
RAB27A and RAB27B Expression May Predict Lymph Node Metastasis and Survival in Patients With Gastric Cancer
HYO JUNG AN, JONG SIL LEE, JUNG WOOK YANG, MIN HYE KIM, JI MIN NA, DAE HYUN SONG
Cancer Genomics Proteomics. 2022 Sep-Oct; 19(5): 606–613. Published online 2022 Sep 3. doi: 10.21873/cgp.20345
PMCID:
PMC9353728
AbstractArticlePDF–2.9M
15.
GDP/GTP exchange factor MADD drives activation and recruitment of secretory Rab GTPases to Weibel-Palade bodies
Marije Kat, Petra E. Bürgisser, Hans Janssen, Iris M. De Cuyper, Ianina L. Conte, Alistair N. Hume, Tom Carter, Jan Voorberg, Coert Margadant, Ruben Bierings
Blood Adv. 2021 Dec 14; 5(23): 5116–5127. Published online 2021 Dec 6. doi: 10.1182/bloodadvances.2021004827
PMCID:
PMC9153003
AbstractArticlePDF–4.4M
16.
The proximal proteome of 17 SARS-CoV-2 proteins links to disrupted antiviral signaling and host translation
Jordan M. Meyers, Muthukumar Ramanathan, Ronald L. Shanderson, Aimee Beck, Laura Donohue, Ian Ferguson, Margaret G. Guo, Deepti S. Rao, Weili Miao, David Reynolds, Xue Yang, Yang Zhao, Yen-Yu Yang, Catherine Blish, Yinsheng Wang, Paul A. Khavari
PLoS Pathog. 2021 Oct; 17(10): e1009412. Published online 2021 Oct 1. doi: 10.1371/journal.ppat.1009412
PMCID:
PMC8513853
AbstractArticlePDF–4.1M
17.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
18.
Griscelli Syndrome Type 2 Sine Albinism: Unraveling Differential RAB27A Effector Engagement
Yuta Ohishi, Sandra Ammann, Vahid Ziaee, Katharina Strege, Miriam Groß, Carla Vazquez Amos, Mohammad Shahrooei, Parisa Ashournia, Anahita Razaghian, Gillian M. Griffiths, Stephan Ehl, Mitsunori Fukuda, Nima Parvaneh
Front Immunol. 2020; 11: 612977. Published online 2020 Dec 10. doi: 10.3389/fimmu.2020.612977
PMCID:
PMC7758216
AbstractArticlePDF–4.9M
19.
In silico APC/C substrate discovery reveals cell cycle-dependent degradation of UHRF1 and other chromatin regulators
Jennifer L. Franks, Raquel C. Martinez-Chacin, Xianxi Wang, Rochelle L. Tiedemann, Thomas Bonacci, Rajarshi Choudhury, Derek L. Bolhuis, Taylor P. Enrico, Ryan D. Mouery, Jeffrey S. Damrauer, Feng Yan, Joseph S. Harrison, M. Ben Major, Katherine A. Hoadley, Aussie Suzuki, Scott B. Rothbart, Nicholas G. Brown, Michael J. Emanuele
PLoS Biol. 2020 Dec; 18(12): e3000975. Published online 2020 Dec 11. doi: 10.1371/journal.pbio.3000975
PMCID:
PMC7758050
AbstractArticlePDF–4.2M
20.
Rab27A promotes cellular apoptosis and ROS production by regulating the miRNA‐124‐3p/STAT3/RelA signalling pathway in ulcerative colitis
Yang Luo, Min‐Hao Yu, Ya‐Ru Yan, Yong Zhou, Shao‐Lan Qin, Yi‐Zhou Huang, Jun Qin, Ming Zhong
J Cell Mol Med. 2020 Oct; 24(19): 11330–11342. Published online 2020 Aug 20. doi: 10.1111/jcmm.15726
PMCID:
PMC7576264
AbstractArticlePDF–2.9M

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