PMC Links for GEO Profiles (Select 102720048) - PMC

Maria Virginia Giolito, Théo La Rosa, Diana Farhat, Serguei Bodoirat, Gabriela D. A. Guardia, Claire Domon‐Dell, Pedro A. F. Galante, Jean‐Noel Freund, Michelina Plateroti

Mol Oncol. 2022 Dec; 16(22): 3975–3993. Published online 2022 Oct 10. doi: 10.1002/1878-0261.13298

PMCID:: PMC9718118

Abstract Article PDF–2.2M

Select item 94754624.

ARHGAP24 represses β-catenin transactivation-induced invasiveness in hepatocellular carcinoma mainly by acting as a GTPase-independent scaffold

Wenjing Yang, Beili Wang, Qian Yu, Te Liu, Tong Li, Tongtong Tian, Anli Jin, Lin Ding, Wei Chen, Hao Wang, Jingrong Xian, Baishen Pan, Jian Zhou, Jia Fan, Xinrong Yang, Wei Guo

Theranostics. 2022; 12(14): 6189–6206. Published online 2022 Aug 21. doi: 10.7150/thno.72134

PMCID:: PMC9475462

Abstract Article PDF–4.6M

Select item 86910185.

Low thyroid hormone receptor alpha-2 (THRα-2) tumor expression is associated with unfavorable tumor characteristics and high breast cancer mortality

Malte Sandsveden, Signe Borgquist, Ann H. Rosendahl, Jonas Manjer

Breast Cancer Res. 2021; 23: 117. Published online 2021 Dec 20. doi: 10.1186/s13058-021-01496-7

PMCID:: PMC8691018

Abstract Article PDF–1.4M

Select item 82903136.

Germ Line Mutations in the Thyroid Hormone Receptor Alpha Gene Predispose to Cutaneous Tags and Melanocytic Nevi

Emery Di Cicco, Carla Moran, W. Edward Visser, Annarita Nappi, Erik Schoenmakers, Pamela Todd, Greta Lyons, Mehul Dattani, Raffaele Ambrosio, Silvia Parisi, Domenico Salvatore, Krishna Chatterjee, Monica Dentice

Thyroid. July 2021; 31(7): 1114–1126. Published online 2021 Jul 8. doi: 10.1089/thy.2020.0391

PMCID:: PMC8290313

Abstract Article PDF–2.1M

Select item 81591257.

A New Mechanism in THRA Resistance: The First Disease-Associated Variant Leading to an Increased Inhibitory Function of THRA2

Sarah Paisdzior, Ellen Knierim, Gunnar Kleinau, Heike Biebermann, Heiko Krude, Rachel Straussberg, Markus Schuelke

Int J Mol Sci. 2021 May; 22(10): 5338. Published online 2021 May 19. doi: 10.3390/ijms22105338

PMCID:: PMC8159125

Abstract Article PDF–1.1M

Select item 80420048.

Thyroid hormone receptor α1 acts as a new squamous cell lung cancer diagnostic marker and poor prognosis predictor

Fatma El Zahraa A. Mohamed, Ali Omar Abdelaziz, Ahmed Hussein Kasem, Tarek Ellethy, Mariana F. Gayyed

Sci Rep. 2021; 11: 7944. Published online 2021 Apr 12. doi: 10.1038/s41598-021-86754-6

PMCID:: PMC8042004

Abstract Article PDF–1.6M

Select item 79472739.

Life Without Thyroid Hormone Receptor

Yun-Bo Shi

Endocrinology. 2021 Apr; 162(4): bqab028. Published online 2021 Feb 9. doi: 10.1210/endocr/bqab028

PMCID:: PMC7947273

Abstract Article

Select item 790504010.

Molecular Characterization of the Oncogene BTF3 and Its Targets in Colorectal Cancer

Hantao Wang, Junjie Xing, Wei Wang, Guifen Lv, Haiyan He, Yeqing Lu, Mei Sun, Haiyan Chen, Xu Li

Front Cell Dev Biol. 2020; 8: 601502. Published online 2021 Feb 11. doi: 10.3389/fcell.2020.601502

PMCID:: PMC7905040

Abstract Article PDF–3.2M

Select item 756688111.

Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism

Michael Aregger, Keith A. Lawson, Maximillian Billmann, Michael Costanzo, Amy H. Y. Tong, Katherine Chan, Mahfuzur Rahman, Kevin R. Brown, Catherine Ross, Matej Usaj, Lucy Nedyalkova, Olga Sizova, Andrea Habsid, Judy Pawling, Zhen-Yuan Lin, Hala Abdouni, Cassandra J. Wong, Alexander Weiss, Patricia Mero, James W. Dennis, Anne-Claude Gingras, Chad L. Myers, Brenda J. Andrews, Charles Boone, Jason Moffat

Nat Metab. Author manuscript; available in PMC 2020 Dec 1.

Published in final edited form as: Nat Metab. 2020 Jun; 2(6): 499–513. Published online 2020 Jun 1. doi: 10.1038/s42255-020-0211-z

PMCID:: PMC7566881

Abstract Article PDF–4.8M

Select item 738910912.

先天性甲状腺功能减退症患儿GNAS和THRA基因突变分析

陈晓宇, 刘勇, 刘建华, 秦晓松

Zhongguo Dang Dai Er Ke Za Zhi. 2019 Jul 25; 21(7): 680–684. Chinese. doi: 10.7499/j.issn.1008-8830.2019.07.012

PMCID:: PMC7389109

Abstract Article PDF–1.2M

Select item 716998313.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 694204414.

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity

Jae Jin Kim, Seo Yun Lee, Fade Gong, Anna M. Battenhouse, Daniel R. Boutz, Aarti Bashyal, Samantha T. Refvik, Cheng-Ming Chiang, Blerta Xhemalce, Tanya T. Paull, Jennifer S. Brodbelt, Edward M. Marcotte, Kyle M. Miller

Genes Dev. 2019 Dec 1; 33(23-24): 1751–1774. doi: 10.1101/gad.331231.119

PMCID:: PMC6942044

Abstract Article PDF–10M

Select item 684261515.

Mutations in thyroid hormone receptor α1 cause premature neurogenesis and progenitor cell depletion in human cortical development

Teresa G. Krieger, Carla M. Moran, Alberto Frangini, W. Edward Visser, Erik Schoenmakers, Francesco Muntoni, Chris A. Clark, David Gadian, Wui K. Chong, Adam Kuczynski, Mehul Dattani, Greta Lyons, Alexandra Efthymiadou, Faraneh Vargha-Khadem, Benjamin D. Simons, Krishna Chatterjee, Frederick J. Livesey

Proc Natl Acad Sci U S A. 2019 Nov 5; 116(45): 22754–22763. Published online 2019 Oct 18. doi: 10.1073/pnas.1908762116

Correction in:: Proc Natl Acad Sci U S A. 2020 Mar 31; 117(13): 7537–7538.

PMCID:: PMC6842615

Abstract Article PDF–2.5M

Select item 679538716.

Alteration of thyroid hormone signaling triggers the diabetes-induced pathological growth, remodeling, and dedifferentiation of podocytes

Valentina Benedetti, Angelo Michele Lavecchia, Monica Locatelli, Valerio Brizi, Daniela Corna, Marta Todeschini, Rubina Novelli, Ariela Benigni, Carlamaria Zoja, Giuseppe Remuzzi, Christodoulos Xinaris

JCI Insight. 2019 Sep 19; 4(18): e130249. Published online 2019 Sep 19. doi: 10.1172/jci.insight.130249

PMCID:: PMC6795387

Abstract Article PDF–44M

Select item 670847917.

Acetylation modulates thyroid hormone receptor intracellular localization and intranuclear mobility

Cyril S. Anyetei-Anum, Rochelle M. Evans, Amanda M. Back, Vincent R. Roggero, Lizabeth A. Allison

Mol Cell Endocrinol. Author manuscript; available in PMC 2020 Sep 15.

Published in final edited form as: Mol Cell Endocrinol. 2019 Sep 15; 495: 110509. Published online 2019 Jul 15. doi: 10.1016/j.mce.2019.110509

PMCID:: PMC6708479

Abstract Article PDF–1.8M

Select item 607552418.

IGF1 neuronal response in the absence of MECP2 is dependent on TRalpha 3

Janaina S. de Souza, Cassiano Carromeu, Laila B. Torres, Bruno H. S. Araujo, Fernanda R. Cugola, Rui M.B. Maciel, Alysson R. Muotri, Gisele Giannocco

Hum Mol Genet. 2017 Jan 15; 26(2): 270–281. Published online 2016 Nov 30. doi: 10.1093/hmg/ddw384

PMCID:: PMC6075524

Abstract Article PDF–567K

Select item 598992619.

Resistance to Thyroid Hormone due to a mutation in thyroid hormone receptor a1 and the a2 variant protein

Carla Moran, Maura Agostini, W. Edward Visser, Erik Schoenmakers, Nadia Schoenmakers, Amaka C. Offiah, Ken Poole, Odelia Rajanayagam, Greta Lyons, David Halsall, Mark Gurnell, Dionisios Chrysis, Alexandra Efthymiadou, Charles Buchanan, Simon Aylwin, Krishna Chatterjee

Lancet Diabetes Endocrinol. Author manuscript; available in PMC 2018 Jun 6.

Published in final edited form as: Lancet Diabetes Endocrinol. 2014 Aug; 2(8): 619–626. Published online 2014 Jun 23. doi: 10.1016/S2213-8587(14)70111-1

PMCID:: PMC5989926

Abstract Article PDF–1.3M

Select item 553161120.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

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