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Select item 111589251.

Inhibition of α‐mannosidase Man2c1 gene expression suppresses growth of esophageal carcinoma cells through mitotic arrest and apoptosis

Yun Tian, Ji Yu Ju, Yi Qun Zhou, Yin Liu, Li Ping Zhu

Cancer Sci. 2008 Dec; 99(12): 2428–2434. Published online 2008 Nov 19. doi: 10.1111/j.1349-7006.2008.01019.x

PMCID:: PMC11158925

Abstract Article PDF–222K

Select item 102374222.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 88742273.

Impaired catabolism of free oligosaccharides due to MAN2C1 variants causes a neurodevelopmental disorder

Nuno Maia, Sven Potelle, Hamide Yildirim, Sandrine Duvet, Shyam K. Akula, Celine Schulz, Elsa Wiame, Alexander Gheldof, Katherine O’Kane, Abbe Lai, Karen Sermon, Maïa Proisy, Philippe Loget, Tania Attié-Bitach, Chloé Quelin, Ana Maria Fortuna, Ana Rita Soares, Arjan P.M. de Brouwer, Emile Van Schaftingen, Marie-Cécile Nassogne, Christopher A. Walsh, Katrien Stouffs, Paula Jorge, Anna C. Jansen, François Foulquier

Am J Hum Genet. 2022 Feb 3; 109(2): 345–360. Published online 2022 Jan 18. doi: 10.1016/j.ajhg.2021.12.010

PMCID:: PMC8874227

Abstract Article PDF–4.7M

Select item 81650304.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 73220675.

RIG-I regulates myeloid differentiation by promoting TRIM25-mediated ISGylation

Song-Fang Wu, Li Xia, Xiao-Dong Shi, Yu-Jun Dai, Wei-Na Zhang, Jun-Mei Zhao, Wu Zhang, Xiang-Qin Weng, Jing Lu, Huang-Ying Le, Sheng-ce Tao, Jiang Zhu, Zhu Chen, Yue-Ying Wang, Saijuan Chen

Proc Natl Acad Sci U S A. 2020 Jun 23; 117(25): 14395–14404. Published online 2020 Jun 8. doi: 10.1073/pnas.1918596117

PMCID:: PMC7322067

Abstract Article PDF–2.7M

Select item 55316116.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 49271427.

Ancient Haplotypes at the 15q24.2 Microdeletion Region Are Linked to Brain Expression of MAN2C1 and Children's Intelligence

Alejandro Cáceres, Tõnu Esko, Irene Pappa, Armand Gutiérrez, Maria-Jose Lopez-Espinosa, Sabrina Llop, Mariona Bustamante, Henning Tiemeier, Andres Metspalu, Peter K. Joshi, James F. Wilsonx, Judith Reina-Castillón, Jean Shin, Zdenka Pausova, Tomáš Paus, Jordi Sunyer, Luis A. Pérez-Jurado, Juan R. González

PLoS One. 2016; 11(6): e0157739. Published online 2016 Jun 29. doi: 10.1371/journal.pone.0157739

PMCID:: PMC4927142

Abstract Article PDF–2.4M

Select item 46172118.

The BioPlex Network: A Systematic Exploration of the Human Interactome

Edward L. Huttlin, Lily Ting, Raphael J. Bruckner, Fana Gebreab, Melanie P. Gygi, John Szpyt, Stanley Tam, Gabriela Zarraga, Greg Colby, Kurt Baltier, Rui Dong, Virginia Guarani, Laura Pontano Vaites, Alban Ordureau, Ramin Rad, Brian K. Erickson, Martin Wühr, Joel Chick, Bo Zhai, Deepak Kolippakkam, Julian Mintseris, Robert A. Obar, Tim Harris, Spyros Artavanis-Tsakonas, Mathew E. Sowa, Pietro DeCamilli, Joao A. Paulo, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2016 Jul 16.

Published in final edited form as: Cell. 2015 Jul 16; 162(2): 425–440. doi: 10.1016/j.cell.2015.06.043

PMCID:: PMC4617211

Abstract Article PDF–2.2M

Select item 40647189.

Charting the Landscape of Tandem BRCT Domain-Mediated Protein Interactions

Nicholas T. Woods, Rafael D. Mesquita, Michael Sweet, Marcelo A. Carvalho, Xueli Li, Yun Liu, Huey Nguyen, C. Eric Thomas, Edwin S. Iversen, Jr., Sylvia Marsillac, Rachel Karchin, John Koomen, Alvaro N.A. Monteiro

Sci Signal. Author manuscript; available in PMC 2014 Jun 20.

Published in final edited form as: Sci Signal. 2012; 5(242): rs6. Published online 2012 Sep 18. doi: 10.1126/scisignal.2002255

PMCID:: PMC4064718

Abstract Article PDF–2.1M

Select item 365847410.

Glycosylation Site-Specific Analysis of HIV Envelope Proteins (JR-FL and CON-S) Reveals Major Differences in Glycosylation Site Occupancy, Glycoform Profiles, and Antigenic Epitopes’ Accessibility

Eden P. Go, Janet Irungu, Ying Zhang, Dilusha S. Dalpathado, Hua-Xin Liao, Laura L. Sutherland, S. Munir Alam, Barton F. Haynes, Heather Desaire

J Proteome Res. Author manuscript; available in PMC 2013 May 20.

Published in final edited form as: J Proteome Res. 2008 Apr; 7(4): 1660–1674. Published online 2008 Mar 11. doi: 10.1021/pr7006957

PMCID:: PMC3658474

Abstract Article PDF–6.1M

Select item 363687611.

Dual Functions for Cytosolic α-Mannosidase (Man2C1): ITS DOWN-REGULATION CAUSES MITOCHONDRIA-DEPENDENT APOPTOSIS INDEPENDENTLY OF ITS α-MANNOSIDASE ACTIVITY

Li Wang, Tadashi Suzuki

J Biol Chem. 2013 Apr 26; 288(17): 11887–11896. Published online 2013 Mar 13. doi: 10.1074/jbc.M112.425702

PMCID:: PMC3636876

Abstract Article PDF–2.1M

Select item 318865912.

Gene Expression and Methylation Signatures of MAN2C1 are Associated with PTSD

Monica Uddin, Sandro Galea, Shun-Chiao Chang, Allison E. Aiello, Derek E. Wildman, Regina de los Santos, Karestan C. Koenen

Dis Markers. 2011; 30(2-3): 111–121. Published online 2011 Apr 20. doi: 10.3233/DMA-2011-0750

PMCID:: PMC3188659

Summary PDF–290K

Select item 317805913.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 244148214.

Env length and N-linked glycosylation following transmission of Human Immunodeficiency Virus Type 1 subtype B viruses

Yi Liu, Marcel E. Curlin, Kurt Diem, Hong Zhao, Ananta K. Ghosh, Haiying Zhu, Amanda S. Woodward, Janine Maenza, Claire Stevens, Joanne Stekler, Ann C. Collier, Indira Genowati, Wenjie Deng, Rafael Zioni, Lawrence Corey, Tuofu Zhu, James I. Mullins

Virology. Author manuscript; available in PMC 2009 May 10.

Published in final edited form as: Virology. 2008 May 10; 374(2): 229–233. Published online 2008 Mar 7. doi: 10.1016/j.virol.2008.01.029