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Items: 1 to 20 of 47

1.
Matrigel-based organoid culture of malignant mesothelioma reproduces cisplatin sensitivity through CTR1
Fumiya Ito, Katsuhiro Kato, Izumi Yanatori, Yuki Maeda, Toyoaki Murohara, Shinya Toyokuni
BMC Cancer. 2023; 23: 487. Published online 2023 May 31. doi: 10.1186/s12885-023-10966-4
PMCID:
PMC10230733
AbstractArticlePDF–3.1M
2.
ATF3/SPI1/SLC31A1 Signaling Promotes Cuproptosis Induced by Advanced Glycosylation End Products in Diabetic Myocardial Injury
Shengqi Huo, Qian Wang, Wei Shi, Lulu Peng, Yue Jiang, Mengying Zhu, Junyi Guo, Dewei Peng, Moran Wang, Lintong Men, Bingyu Huang, Jiagao Lv, Li Lin
Int J Mol Sci. 2023 Jan; 24(2): 1667. Published online 2023 Jan 14. doi: 10.3390/ijms24021667
PMCID:
PMC9862315
AbstractArticlePDF–6.6M
3.
Decreased Expression of the Slc31a1 Gene and Cytoplasmic Relocalization of Membrane CTR1 Protein in Renal Epithelial Cells: A Potent Protective Mechanism against Copper Nephrotoxicity in a Mouse Model of Menkes Disease
Olga Haberkiewicz, Paweł Lipiński, Rafał R. Starzyński, Aneta Jończy, Patrycja Kurowska, Mateusz Ogórek, Aleksandra Bednarz, Sylwia Herman, Dawid Hatala, Paweł Grzmil, Zenon Rajfur, Zbigniew Baster, Małgorzata Lenartowicz
Int J Mol Sci. 2022 Oct; 23(19): 11441. Published online 2022 Sep 28. doi: 10.3390/ijms231911441
PMCID:
PMC9570402
AbstractArticlePDF–4.6M
4.
BRAFV600E-Driven Lung Adenocarcinoma Requires Copper to Sustain Autophagic Signaling and Processing
Tiffany Tsang, Xingxing Gu, Caroline I. Davis, Jessica M. Posimo, Zoey A. Miller, Donita C. Brady
Mol Cancer Res. 2022 Jul 6; 20(7): 1096–1107. Published online 2022 Mar 23. doi: 10.1158/1541-7786.MCR-21-0250
PMCID:
PMC9262833
AbstractArticlePDF–1.5M
5.
Oral Elesclomol Treatment Alleviates Copper Deficiency in Animal Models
Sai Yuan, Tamara Korolnek, Byung-Eun Kim
Front Cell Dev Biol. 2022; 10: 856300. Published online 2022 Apr 1. doi: 10.3389/fcell.2022.856300
PMCID:
PMC9010564
AbstractArticlePDF–2.0M
6.
Cysteine Oxidation of Copper transporter SLC31A1/CTR1, drives VEGFR2 signaling and Angiogenesis
Archita Das, Dipankar Ash, Abdelrahman Y. Fouda, Varadarajan Sudhahar, Young-Mee Kim, Yali Hou, Farlyn Z Hudson, Brian K Stansfield, Ruth B. Caldwell, Maggie McMenamin, Rodney Littlejohn, Huabo Su, Maureen R. Regan, Bradley J. Merrill, Leslie B. Poole, Jack H. Kaplan, Tohru Fukai, Masuko Ushio-Fukai
Nat Cell Biol. Author manuscript; available in PMC 2022 Jul 13.
Published in final edited form as: Nat Cell Biol. 2022 Jan; 24(1): 35–50. Published online 2022 Jan 13. doi: 10.1038/s41556-021-00822-7
PMCID:
PMC8851982
AbstractArticlePDF–5.8M
7.
A cellular and spatial map of the choroid plexus across brain ventricles and ages
Neil Dani, Rebecca H. Herbst, Cristin McCabe, Gilad Green, Karol Kaiser, Joshua Head, Jin Cui, Frederick B. Shipley, Ahram Jang, Danielle Dionne, Lan Nguyen, Christopher Rodman, Samantha J. Riesenfeld, Jan Prochazka, Michaela Prochazkova, Radislav Sedlacek, Feng Zhang, Vitezslav Bryja, Orit Rozenblatt-Rosen, Naomi Habib, Aviv Regev, Maria K. Lehtinen
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3056–3074.e21. Published online 2021 Apr 30. doi: 10.1016/j.cell.2021.04.003
PMCID:
PMC8214809
AbstractArticlePDF–3.5M
8.
Inhibition of copper transporter 1 prevents α-synuclein pathology and alleviates nigrostriatal degeneration in AAV-based mouse model of Parkinson's disease
De-Hai Gou, Ting-Ting Huang, Wen Li, Xin-Di Gao, Caroline Haikal, Xin-He Wang, Dong-Yan Song, Xin Liang, Lin Zhu, Yong Tang, Chen Ding, Jia-Yi Li
Redox Biol. 2021 Jan; 38: 101795. Published online 2020 Nov 12. doi: 10.1016/j.redox.2020.101795
PMCID:
PMC7691620
AbstractArticlePDF–18M
9.
Elesclomol alleviates Menkes pathology and mortality by escorting Cu to cuproenzymes in mice
Liam M. Guthrie, Shivatheja Soma, Sai Yuan, Andres Silva, Mohammad Zulkifli, Thomas C. Snavely, Hannah Faith Greene, Elyssa Nunez, Brogan Lynch, Courtney De Ville, Vinit Shanbhag, Franklin R. Lopez, Arjun Acharya, Michael J. Petris, Byung-Eun Kim, Vishal M. Gohil, James C. Sacchettini
Science. Author manuscript; available in PMC 2020 Jun 19.
Published in final edited form as: Science. 2020 May 8; 368(6491): 620–625. doi: 10.1126/science.aaz8899
PMCID:
PMC7304446
AbstractArticlePDF–1.5M
10.
Copper transporter 1 (CTR1) expression by mouse testicular germ cells, but not Sertoli cells, is essential for functional spermatogenesis
Rashin Ghaffari, Kristin R. Di Bona, Christopher L. Riley, John H. Richburg
PLoS One. 2019; 14(4): e0215522. Published online 2019 Apr 19. doi: 10.1371/journal.pone.0215522
PMCID:
PMC6474593
AbstractArticlePDF–5.1M
11.
Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors
Hyeonwoo Kim, Christiane D. Wrann, Mark Jedrychowski, Sara Vidoni, Yukiko Kitase, Kenichi Nagano, Chenhe Zhou, Joshua Chou, Virginia-Jeni A. Parkman, Scott J. Novick, Timothy S. Strutzenberg, Bruce D. Pascal, Phuong T. Le, Daniel J. Brooks, Alexander M. Roche, Kaitlyn K. Gerber, Laura Mattheis, Wenjing Chen, Hua Tu, Mary L. Bouxsein, Patrick R. Griffin, Roland Baron, Clifford J. Rosen, Lynda F. Bonewald, Bruce M. Spiegelman
Cell. Author manuscript; available in PMC 2019 Dec 13.
Published in final edited form as: Cell. 2018 Dec 13; 175(7): 1756–1768.e17. doi: 10.1016/j.cell.2018.10.025
Correction in:
Cell. 2019 Jul 11; 178(2): 507–508.
PMCID:
PMC6298040
AbstractArticlePDF–1.2M
12.
The mitochondrial metallochaperone SCO1 maintains CTR1 at the plasma membrane to preserve copper homeostasis in the murine heart
Zakery N Baker, Kimberly Jett, Aren Boulet, Amzad Hossain, Paul A Cobine, Byung-Eun Kim, Amr M El Zawily, Ling Lee, Glen F Tibbits, Michael J Petris, Scot C Leary
Hum Mol Genet. 2017 Dec 1; 26(23): 4617–4628. Published online 2017 Sep 4. doi: 10.1093/hmg/ddx344
PMCID:
PMC5886179
AbstractArticlePDF–1.2M
13.
Copper Chelation Inhibits BRAFV600E-driven Melanomagenesis and Counters Resistance to BRAFV600E and MEK1/2 Inhibitors
Donita C. Brady, Matthew S. Crowe, Danielle N. Greenberg, Christopher M. Counter
Cancer Res. Author manuscript; available in PMC 2018 Nov 15.
Published in final edited form as: Cancer Res. 2017 Nov 15; 77(22): 6240–6252. Published online 2017 Oct 6. doi: 10.1158/0008-5472.CAN-16-1190
PMCID:
PMC5690876
AbstractArticlePDF–1.0M
14.
Sexual congruency in the connectome and translatome of VTA dopamine neurons
Amanda S. Chung, Samara M. Miller, Yanjun Sun, Xiangmin Xu, Larry S. Zweifel
Sci Rep. 2017; 7: 11120. Published online 2017 Sep 11. doi: 10.1038/s41598-017-11478-5
PMCID:
PMC5593921
AbstractArticlePDF–6.4M
15.
Gene duplication and neo-functionalization in the evolutionary and functional divergence of the metazoan copper transporters Ctr1 and Ctr2
Brandon L. Logeman, L. Kent Wood, Jaekwon Lee, Dennis J. Thiele
J Biol Chem. 2017 Jul 7; 292(27): 11531–11546. Published online 2017 May 15. doi: 10.1074/jbc.M117.793356
PMCID:
PMC5500815
AbstractArticlePDF–3.6M
16.
Histidine phosphorylation relieves copper inhibition in the mammalian potassium channel KCa3.1
Shekhar Srivastava, Saswati Panda, Zhai Li, Stephen R Fuhs, Tony Hunter, Dennis J Thiele, Stevan R Hubbard, Edward Y Skolnik
eLife. 2016; 5: e16093. Published online 2016 Aug 19. doi: 10.7554/eLife.16093
PMCID:
PMC5005030
AbstractArticlePDF–1.4M
17.
Cathepsin Protease Controls Copper and Cisplatin Accumulation via Cleavage of the Ctr1 Metal-binding Ectodomain
Helena Öhrvik, Brandon Logeman, Boris Turk, Thomas Reinheckel, Dennis J. Thiele
J Biol Chem. 2016 Jul 1; 291(27): 13905–13916. Published online 2016 May 3. doi: 10.1074/jbc.M116.731281
PMCID:
PMC4933151
AbstractArticlePDF–1.4M
18.
Molecular modulation of the copper and cisplatin transport function of CTR1 and its interaction with IRS-4
Cheng-Yu Tsai, Christopher A. Larson, Roohangiz Safaei, Stephen B. Howell
Biochem Pharmacol. Author manuscript; available in PMC 2015 Feb 27.
Published in final edited form as: Biochem Pharmacol. 2014 Aug 15; 90(4): 379–387. Published online 2014 Jun 23. doi: 10.1016/j.bcp.2014.06.019
PMCID:
PMC4343213
AbstractArticlePDF–802K
19.
Copper is an endogenous modulator of neural circuit spontaneous activity
Sheel C. Dodani, Alana Firl, Jefferson Chan, Christine I. Nam, Allegra T. Aron, Carl S. Onak, Karla M. Ramos-Torres, Jaeho Paek, Corey M. Webster, Marla B. Feller, Christopher J. Chang
Proc Natl Acad Sci U S A. 2014 Nov 18; 111(46): 16280–16285. Published online 2014 Nov 5. doi: 10.1073/pnas.1409796111
PMCID:
PMC4246333
AbstractArticlePDF–1.1M
20.
Copper is required for oncogenic BRAF signaling and tumorigenesis
Donita C. Brady, Matthew S. Crowe, Michelle L. Turski, G. Aaron Hobbs, Xiaojie Yao, Apirat Chaikuad, Stefan Knapp, Kunhong Xiao, Sharon L. Campbell, Dennis J. Thiele, Christopher M. Counter
Nature. Author manuscript; available in PMC 2014 Nov 22.
Published in final edited form as: Nature. 2014 May 22; 509(7501): 492–496. Published online 2014 Apr 9. doi: 10.1038/nature13180
PMCID:
PMC4138975
AbstractArticlePDF–1.7M

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