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Items: 1 to 20 of 31

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Jacob‐induced transcriptional inactivation of CREB promotes Aβ‐induced synapse loss in Alzheimer's disease
Katarzyna M Grochowska, Guilherme M Gomes, Rajeev Raman, Rahul Kaushik, Liudmila Sosulina, Hiroshi Kaneko, Anja M Oelschlegel, PingAn Yuanxiang, Irene Reyes‐Resina, Gonca Bayraktar, Sebastian Samer, Christina Spilker, Marcel S Woo, Markus Morawski, Jürgen Goldschmidt, Manuel A Friese, Steffen Rossner, Gemma Navarro, Stefan Remy, Carsten Reissner, Anna Karpova, Michael R Kreutz
EMBO J. 2023 Feb; 42(4): e112453. Published online 2023 Jan 3. doi: 10.15252/embj.2022112453
PMCID:
PMC9929644
AbstractArticlePDF–15M
3.
A Jacob/nsmf gene knockout does not protect against acute hypoxia- and NMDA-induced excitotoxic cell death
Guilherme M. Gomes, Julia Bär, Anna Karpova, Michael R. Kreutz
Mol Brain. 2023; 16: 23. Published online 2023 Feb 11. doi: 10.1186/s13041-023-01012-2
PMCID:
PMC9921040
AbstractArticlePDF–994K
4.
RNA polymerase II pausing factor NELF in CD8+ T cells promotes antitumor immunity
Bogang Wu, Xiaowen Zhang, Huai-Chin Chiang, Haihui Pan, Bin Yuan, Payal Mitra, Leilei Qi, Hayk Simonyan, Colin N. Young, Eric Yvon, Yanfen Hu, Nu Zhang, Rong Li
Nat Commun. 2022; 13: 2155. Published online 2022 Apr 20. doi: 10.1038/s41467-022-29869-2
PMCID:
PMC9021285
AbstractArticlePDF–2.1M
5.
Epithelial NELF guards intestinal barrier function to ameliorate colitis by maintaining junctional integrity
Jiayao Ou, Xiaoxing Guan, Jiali Wang, Tianjiao Wang, Bin Zhang, Rong Li, Huji Xu, Xiaoyu Hu, Xue-Kun Guo
Mucosal Immunol. Author manuscript; available in PMC 2022 Feb 26.
Published in final edited form as: Mucosal Immunol. 2022 Feb; 15(2): 279–288. Published online 2021 Oct 25. doi: 10.1038/s41385-021-00465-9
PMCID:
PMC8881342
AbstractArticlePDF–2.2M
6.
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development
Francesco Bedogni, Robert F. Hevner
Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034
PMCID:
PMC8313239
AbstractArticlePDF–1.6M
7.
NSMF promotes the replication stress-induced DNA damage response for genome maintenance
Min Kyung Ju, Kyeong Jin Shin, Joo Rak Lee, Keon Woo Khim, Eun A. Lee, Jae Sun Ra, Byung-Gyu Kim, Han-seul Jo, Jong Hyuk Yoon, Tae Moon Kim, Kyungjae Myung, Jang Hyun Choi, Hongtae Kim, Young Chan Chae
Nucleic Acids Res. 2021 Jun 4; 49(10): 5605–5622. Published online 2021 May 8. doi: 10.1093/nar/gkab311
PMCID:
PMC8191778
AbstractArticlePDF–7.1M
8.
NELF regulates a promoter-proximal step distinct from RNA Pol II pause-release
Yuki Aoi, Edwin R. Smith, Avani P. Shah, Emily J. Rendleman, Stacy A. Marshall, Ashley R. Woodfin, Fei X. Chen, Ramin Shiekhattar, Ali Shilatifard
Mol Cell. Author manuscript; available in PMC 2021 Apr 16.
Published in final edited form as: Mol Cell. 2020 Apr 16; 78(2): 261–274.e5. Published online 2020 Mar 9. doi: 10.1016/j.molcel.2020.02.014
PMCID:
PMC7402197
AbstractArticlePDF–1.0M
9.
Overlapping Activities of Two Neuronal Splicing Factors Switch the GABA Effect from Excitatory to Inhibitory by Regulating REST
Yoko Nakano, Susan Wiechert, Botond Bánfi
Cell Rep. Author manuscript; available in PMC 2019 Jun 9.
Published in final edited form as: Cell Rep. 2019 Apr 16; 27(3): 860–871.e8. doi: 10.1016/j.celrep.2019.03.072
PMCID:
PMC6556397
AbstractArticlePDF–2.3M
10.
Mouse screen reveals multiple new genes underlying mouse and human hearing loss
Neil J. Ingham, Selina A. Pearson, Valerie E. Vancollie, Victoria Rook, Morag A. Lewis, Jing Chen, Annalisa Buniello, Elisa Martelletti, Lorenzo Preite, Chi Chung Lam, Felix D. Weiss, Zӧe Powis, Pim Suwannarat, Christopher J. Lelliott, Sally J. Dawson, Jacqueline K. White, Karen P. Steel
PLoS Biol. 2019 Apr; 17(4): e3000194. Published online 2019 Apr 11. doi: 10.1371/journal.pbio.3000194
PMCID:
PMC6459510
AbstractArticlePDF–5.1M
11.
A Jacob/Nsmf Gene Knockout Results in Hippocampal Dysplasia and Impaired BDNF Signaling in Dendritogenesis
Christina Spilker, Sven Nullmeier, Katarzyna M. Grochowska, Anne Schumacher, Ioana Butnaru, Tamar Macharadze, Guilherme M. Gomes, PingAn Yuanxiang, Gonca Bayraktar, Carolin Rodenstein, Carolin Geiseler, Angela Kolodziej, Jeffrey Lopez-Rojas, Dirk Montag, Frank Angenstein, Julia Bär, Wolfgang D’Hanis, Thomas Roskoden, Marina Mikhaylova, Eike Budinger, Frank W. Ohl, Oliver Stork, Ana C. Zenclussen, Anna Karpova, Herbert Schwegler, Michael R. Kreutz
PLoS Genet. 2016 Mar; 12(3): e1005907. Published online 2016 Mar 15. doi: 10.1371/journal.pgen.1005907
PMCID:
PMC4792503
AbstractArticlePDF–15M
12.
NELF knockout is associated with impaired pubertal development and subfertility
Samuel D. Quaynor, Eun Kyung Ko, Lynn P. Chorich, Megan E. Sullivan, Durkadin Demir, Jennifer L. Waller, Hyung-Goo Kim, Richard S. Cameron, Lawrence C. Layman
Mol Cell Endocrinol. Author manuscript; available in PMC 2016 May 15.
Published in final edited form as: Mol Cell Endocrinol. 2015 May 15; 407: 26–36. Published online 2015 Feb 27. doi: 10.1016/j.mce.2015.02.015
PMCID:
PMC4429764
AbstractArticlePDF–1.5M
13.
Negative Elongation Factor Controls Energy Homeostasis in Cardiomyocytes
Haihui Pan, Kunhua Qin, Zhanyong Guo, Yonggang Ma, Craig April, Xiaoli Gao, Thomas G. Andrews, Alex Bokov, Jianhua Zhang, Yidong Chen, Susan T. Weintraub, Jian-Bing Fan, Degeng Wang, Yanfen Hu, Gregory J. Aune, Merry L. Lindsey, Rong Li
Cell Rep. Author manuscript; available in PMC 2014 Dec 26.
Published in final edited form as: Cell Rep. 2014 Apr 10; 7(1): 79–85. Published online 2014 Mar 20. doi: 10.1016/j.celrep.2014.02.028
PMCID:
PMC4277258
AbstractArticlePDF–1.1M
14.
Differential Expression of Nasal Embryonic LHRH Factor (NELF) Variants in Immortalized GnRH Neuronal Cell Lines
Samuel D. Quaynor, Lindsey Y. Goldberg, Eun Kyung Ko, Robert K. Stanley, Durkadin Demir, Hyung-Goo Kim, Lynn P. Chorich, Richard S. Cameron, Lawrence C. Layman
Mol Cell Endocrinol. Author manuscript; available in PMC 2015 Mar 5.
Published in final edited form as: Mol Cell Endocrinol. 2014 Mar 5; 383(0): 32–37. Published online 2013 Dec 4. doi: 10.1016/j.mce.2013.11.020
PMCID:
PMC3930684
AbstractArticlePDF–737K
15.
When Synaptic Proteins Meet the Genome: Transcriptional Regulation in Cell Death and Plasticity by the Synapto–Nuclear Messenger Jacob
Sujoy Bera, Michael R Kreutz
Neuropsychopharmacology. 2014 Jan; 39(1): 245–246. Published online 2013 Dec 9. doi: 10.1038/npp.2013.204
PMCID:
PMC3857651
ArticlePDF–190K
16.
BRD4 Coordinates Recruitment of Pause Release Factor P-TEFb and the Pausing Complex NELF/DSIF To Regulate Transcription Elongation of Interferon-Stimulated Genes
Mira C. Patel, Maxime Debrosse, Matthew Smith, Anup Dey, Walter Huynh, Naoyuki Sarai, Tom D. Heightman, Tomohiko Tamura, Keiko Ozato
Mol Cell Biol. 2013 Jun; 33(12): 2497–2507. doi: 10.1128/MCB.01180-12
PMCID:
PMC3700095
AbstractArticlePDF–2.5M
17.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M
18.
NELF Is a Nuclear Protein Involved in Hypothalamic GnRH Neuronal Migration
Ning Xu, Balasubramanian Bhagavath, Hyung-Goo Kim, Lisa Halvorson, Robert S. Podolsky, Lynn P. Chorich, Puttur Prasad, Wen-Cheng Xiong, Richard S. Cameron, Lawrence C. Layman
Mol Cell Endocrinol. Author manuscript; available in PMC 2012 Sep 10.
Published in final edited form as: Mol Cell Endocrinol. 2010 May 5; 319(1-2): 47–55. Published online 2009 Dec 16. doi: 10.1016/j.mce.2009.11.016
PMCID:
PMC3437992
AbstractArticlePDF–1.2M
19.
Differential gene expression in migratory streams of cortical interneurons
Mary Antypa, Clare Faux, Gregor Eichele, John G Parnavelas, William D Andrews
Eur J Neurosci. 2011 Nov; 34(10): 1584–1594. doi: 10.1111/j.1460-9568.2011.07896.x
PMCID:
PMC3401901
AbstractArticlePDF–840K
20.
Developmental Controls are Re-Expressed during Induction of Neurogenesis in the Neocortex of Young Adult Mice
U. Shivraj Sohur, Paola Arlotta, Jeffrey D. Macklis
Front Neurosci. 2012; 6: 12. Published online 2012 Feb 6. doi: 10.3389/fnins.2012.00012
PMCID:
PMC3272649
AbstractArticlePDF–526K

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