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Items: 1 to 20 of 49

1.
RNF8 ubiquitylation of XRN2 facilitates R-loop resolution and restrains genomic instability in BRCA1 mutant cells
Rehna Krishnan, Mariah Lapierre, Brandon Gautreau, Kevin C J Nixon, Samah El Ghamrasni, Parasvi S Patel, Jun Hao, V Talya Yerlici, Kiran Kumar Naidu Guturi, Jonathan St-Germain, Francesca Mateo, Amine Saad, Arash Algouneh, Rebecca Earnshaw, Duan Shili, Alma Seitova, Joshua Miller, Negin Khosraviani, Adam Penn, Brandon Ho, Otto Sanchez, M Prakash Hande, Jean-Yves Masson, Grant W Brown, Moulay Alaoui-Jamali, John J Reynolds, Cheryl Arrowsmith, Brian Raught, Miguel A Pujana, Karim Mekhail, Grant S Stewart, Anne Hakem, Razqallah Hakem
Nucleic Acids Res. 2023 Oct 27; 51(19): 10484–10505. Published online 2023 Sep 11. doi: 10.1093/nar/gkad733
PMCID:
PMC10602868
AbstractArticlePDF–2.1M
2.
Neuroprotective Effect of E3 Ubiquitin Ligase RNF8 Against Ischemic Stroke via HDAC2 Stability Reduction and Reelin-Dependent GSK3β Inhibition
Xiaoxi Zhu, Junxiang Li, Dengwei You, Yan Xiao, Zhi Huang, Wenfeng Yu
Mol Neurobiol. 2022; 59(8): 4776–4790. Published online 2022 May 27. doi: 10.1007/s12035-022-02880-w
Correction in:
Mol Neurobiol. 2022; 59(8): 4791–4792.
PMCID:
PMC9135995
AbstractArticlePDF–2.3M
3.
Noncanonical genomic imprinting in the monoamine system determines naturalistic foraging and brain-adrenal axis functions
Paul J. Bonthuis, Susan Steinwand, Cornelia N. Stacher Hörndli, Jared Emery, Wei-Chao Huang, Stephanie Kravitz, Elliott Ferris, Christopher Gregg
Cell Rep. Author manuscript; available in PMC 2022 May 24.
Published in final edited form as: Cell Rep. 2022 Mar 8; 38(10): 110500. doi: 10.1016/j.celrep.2022.110500
PMCID:
PMC9128000
AbstractArticlePDF–4.5M
4.
RNF8 is not required for histone-to-protamine exchange in spermiogenesis
Hironori Abe, Rajyalakshmi Meduri, Ziwei Li, Paul R Andreassen, Satoshi H Namekawa
Biol Reprod. 2021 Nov; 105(5): 1154–1159. Published online 2021 Jul 5. doi: 10.1093/biolre/ioab132
PMCID:
PMC8599036
AbstractArticlePDF–687K
5.
BRCA1 haploinsufficiency is masked by RNF168-mediated chromatin ubiquitylation
Dali Zong, Salomé Adam, Yifan Wang, Hiroyuki Sasanuma, Elsa Callén, Matilde Murga, Amanda Day, Michael J. Kruhlak, Nancy Wong, Meagan Munro, Arnab Ray Chaudhuri, Baktiar Karim, Bing Xia, Shunichi Takeda, Neil Johnson, Daniel Durocher, André Nussenzweig
Mol Cell. Author manuscript; available in PMC 2020 Mar 21.
Published in final edited form as: Mol Cell. 2019 Mar 21; 73(6): 1267–1281.e7. Published online 2019 Jan 28. doi: 10.1016/j.molcel.2018.12.010
PMCID:
PMC6430682
AbstractArticlePDF–2.3M
6.
Ubiquitin ligase RNF8 suppresses Notch signaling to regulate mammary development and tumorigenesis
Li Li, Kiran Kumar Naidu Guturi, Brandon Gautreau, Parasvi S. Patel, Amine Saad, Mayako Morii, Francesca Mateo, Luis Palomero, Haithem Barbour, Antonio Gomez, Deborah Ng, Max Kotlyar, Chiara Pastrello, Hartland W. Jackson, Rama Khokha, Igor Jurisica, El Bachir Affar, Brian Raught, Otto Sanchez, Moulay Alaoui-Jamali, Miguel A. Pujana, Anne Hakem, Razq Hakem
J Clin Invest. 2018 Oct 1; 128(10): 4525–4542. Published online 2018 Aug 2. doi: 10.1172/JCI120401
Correction in:
J Clin Invest. 2021 Jul 1; 131(13): e152424.
PMCID:
PMC6160000
AbstractArticlePDF–21M
7.
Ubiquitination-Deficient Mutations in Human Piwi Cause Male Infertility by Impairing Histone-to-Protamine Exchange during Spermiogenesis
Lan-Tao Gou, Jun-Yan Kang, Peng Dai, Xin Wang, Feng Li, Shuang Zhao, Man Zhang, Min-Min Hua, Yi Lu, Yong Zhu, Zheng Li, Hong Chen, Li-Gang Wu, Dangsheng Li, Xiang-Dong Fu, Jinsong Li, Hui-Juan Shi, Mo-Fang Liu
Cell. Author manuscript; available in PMC 2018 Jun 3.
Published in final edited form as: Cell. 2017 Jun 1; 169(6): 1090–1104.e13. Published online 2017 May 25. doi: 10.1016/j.cell.2017.04.034
PMCID:
PMC5985145
AbstractArticlePDF–1.0M
8.
Function of RAD6B and RNF8 in spermatogenesis
Yingli Guo, Yanfeng Song, Zhao Guo, Mengjin Hu, Bing Liu, Hongyu Duan, Le Wang, Tianxia Yuan, Degui Wang
Cell Cycle. 2018; 17(2): 162–173. Published online 2018 Jan 19. doi: 10.1080/15384101.2017.1361066
PMCID:
PMC5884393
AbstractArticlePDF–1.6M
9.
RNF8 and SCML2 cooperate to regulate ubiquitination and H3K27 acetylation for escape gene activation on the sex chromosomes
Shannel R. Adams, So Maezawa, Kris G. Alavattam, Hironori Abe, Akihiko Sakashita, Megan Shroder, Tyler J. Broering, Julie Sroga Rios, Michael A. Thomas, Xinhua Lin, Carolyn M. Price, Artem Barski, Paul R. Andreassen, Satoshi H. Namekawa
PLoS Genet. 2018 Feb; 14(2): e1007233. Published online 2018 Feb 20. doi: 10.1371/journal.pgen.1007233
PMCID:
PMC5834201
AbstractArticlePDF–41M
10.
RNF8/UBC13 ubiquitin signaling suppresses synapse formation in the mammalian brain
Pamela Valnegri, Ju Huang, Tomoko Yamada, Yue Yang, Luis A. Mejia, Ha Y. Cho, Anna Oldenborg, Azad Bonni
Nat Commun. 2017; 8: 1271. Published online 2017 Nov 2. doi: 10.1038/s41467-017-01333-6
PMCID:
PMC5668370
AbstractArticlePDF–2.2M
11.
Elucidation of the Fanconi Anemia Protein Network in Meiosis and Its Function in the Regulation of Histone Modifications
Kris G. Alavattam, Yasuko Kato, Ho-Su Sin, So Maezawa, Ian J. Kowalski, Fan Zhang, Qishen Pang, Paul R. Andreassen, Satoshi H. Namekawa
Cell Rep. Author manuscript; available in PMC 2016 Nov 4.
Published in final edited form as: Cell Rep. 2016 Oct 18; 17(4): 1141–1157. doi: 10.1016/j.celrep.2016.09.073
PMCID:
PMC5095620
AbstractArticlePDF–3.6M
12.
JMJD1C Exhibits Multiple Functions in Epigenetic Regulation during Spermatogenesis
Ryusuke Nakajima, Hideyuki Okano, Toshiaki Noce
PLoS One. 2016; 11(9): e0163466. Published online 2016 Sep 20. doi: 10.1371/journal.pone.0163466
PMCID:
PMC5029890
AbstractArticlePDF–4.6M
13.
The DNA damage transducer RNF8 facilitates cancer chemoresistance and progression through Twist activation
Hong-Jen Lee, Chien-Feng Li, Diane Ruan, Scott Powers, Patricia A Thompson, Michael A. Frohman, Chia-Hsin Chan
Mol Cell. Author manuscript; available in PMC 2017 Sep 15.
Published in final edited form as: Mol Cell. 2016 Sep 15; 63(6): 1021–1033. Published online 2016 Sep 8. doi: 10.1016/j.molcel.2016.08.009
PMCID:
PMC5026628
AbstractArticlePDF–2.1M
14.
RNF8 deficiency results in neurodegeneration in mice
Siwei Ouyang, Yanfeng Song, Yingxia Tian, Yibin Chen, Xiaochun Yu, Degui Wang
Neurobiol Aging. Author manuscript; available in PMC 2016 Oct 1.
Published in final edited form as: Neurobiol Aging. 2015 Oct; 36(10): 2850–2860. Published online 2015 Jul 11. doi: 10.1016/j.neurobiolaging.2015.07.010
PMCID:
PMC4851709
AbstractArticlePDF–2.6M
15.
RNF8 E3 Ubiquitin Ligase Stimulates Ubc13 E2 Conjugating Activity That Is Essential for DNA Double Strand Break Signaling and BRCA1 Tumor Suppressor Recruitment
Curtis D. Hodge, Ismail H. Ismail, Ross A. Edwards, Greg L. Hura, Andrew T. Xiao, John A. Tainer, Michael J. Hendzel, J. N. Mark Glover
J Biol Chem. 2016 Apr 29; 291(18): 9396–9410. Published online 2016 Feb 22. doi: 10.1074/jbc.M116.715698
PMCID:
PMC4850281
AbstractArticlePDF–4.6M
16.
FANCB is essential in the male germline and regulates H3K9 methylation on the sex chromosomes during meiosis
Yasuko Kato, Kris G. Alavattam, Ho-Su Sin, Amom Ruhikanta Meetei, Qishen Pang, Paul R. Andreassen, Satoshi H. Namekawa
Hum Mol Genet. 2015 Sep 15; 24(18): 5234–5249. Published online 2015 Jun 29. doi: 10.1093/hmg/ddv244
PMCID:
PMC4550819
AbstractArticlePDF–1.8M
17.
SCML2 Establishes the Male Germline Epigenome through Regulation of Histone H2A Ubiquitination
Kazuteru Hasegawa, Ho-Su Sin, So Maezawa, Tyler J. Broering, Andrey V. Kartashov, Kris G. Alavattam, Yosuke Ichijima, Fan Zhang, W. Clark Bacon, Kenneth D. Greis, Paul R. Andreassen, Artem Barski, Satoshi H. Namekawa
Dev Cell. Author manuscript; available in PMC 2016 Mar 9.
Published in final edited form as: Dev Cell. 2015 Mar 9; 32(5): 574–588. Published online 2015 Feb 19. doi: 10.1016/j.devcel.2015.01.014
PMCID:
PMC4391279
AbstractArticlePDF–6.6M
18.
The E3 ligase RNF8 regulates KU80 removal and NHEJ repair
Lin Feng, Junjie Chen
Nat Struct Mol Biol. Author manuscript; available in PMC 2014 Jan 11.
Published in final edited form as: Nat Struct Mol Biol. 2012 Jan 22; 19(2): 201–206. Published online 2012 Jan 22. doi: 10.1038/nsmb.2211
PMCID:
PMC3888515
AbstractArticlePDF–2.5M
19.
FIGNL1-containing protein complex is required for efficient homologous recombination repair
Jingsong Yuan, Junjie Chen
Proc Natl Acad Sci U S A. 2013 Jun 25; 110(26): 10640–10645. Published online 2013 Jun 10. doi: 10.1073/pnas.1220662110
PMCID:
PMC3696823
AbstractArticlePDF–1.0M
20.
The E3 ubiquitin ligase RNF8 stabilizes TPP1 to promote telomere end protection
Rekha Rai, Ju-Mei Li, Hong Zheng, Gabriel Tsz-Mei Lok, Yu Deng, Michael Huen, Junjie Chen, Jianping Jin, Sandy Chang
Nat Struct Mol Biol. Author manuscript; available in PMC 2013 May 20.
Published in final edited form as: Nat Struct Mol Biol. 2011 Nov 20; 18(12): 1400–1407. Published online 2011 Nov 20. doi: 10.1038/nsmb.2172
PMCID:
PMC3657743
AbstractArticlePDF–1.5M

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