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Items: 1 to 20 of 63

1.
Group 1 metabotropic glutamate receptors trigger glutamate-induced intracellular Ca2+ signals and nitric oxide release in human brain microvascular endothelial cells
Sharon Negri, Pawan Faris, Giorgia Pellavio, Laura Botta, Matteo Orgiu, Greta Forcaia, Giulio Sancini, Umberto Laforenza, Francesco Moccia
Cell Mol Life Sci. 2020 Jun; 77(11): 2235–2253. Published online 2019 Aug 31. doi: 10.1007/s00018-019-03284-1
PMCID:
PMC11104941
AbstractArticlePDF–2.7M
2.
Genetic Variant in GRM1 Underlies Congenital Cerebellar Ataxia with No Obvious Intellectual Disability
Maria S. Protasova, Tatiana V. Andreeva, Sergey A. Klyushnikov, Sergey N. Illarioshkin, Evgeny I. Rogaev
Int J Mol Sci. 2023 Jan; 24(2): 1551. Published online 2023 Jan 12. doi: 10.3390/ijms24021551
PMCID:
PMC9865416
AbstractArticlePDF–1.5M
3.
A Novel Nonsense Variant in GRM1 Causes Autosomal Recessive Spinocerebellar Ataxia 13 in a Consanguineous Pakistani Family
Hammad Yousaf, Ambrin Fatima, Zafar Ali, Shahid M. Baig, Mathias Toft, Zafar Iqbal
Genes (Basel) 2022 Sep; 13(9): 1667. Published online 2022 Sep 17. doi: 10.3390/genes13091667
PMCID:
PMC9498400
AbstractArticlePDF–452K
4.
The Emerging Key Role of the mGluR1-PKCγ Signaling Pathway in the Pathogenesis of Spinocerebellar Ataxias: A Neurodevelopmental Viewpoint
Qin-Wei Wu, Josef P. Kapfhammer
Int J Mol Sci. 2022 Aug; 23(16): 9169. Published online 2022 Aug 15. doi: 10.3390/ijms23169169
PMCID:
PMC9409119
AbstractArticlePDF–1.0M
5.
Proteome‐scale mapping of binding sites in the unstructured regions of the human proteome
Caroline Benz, Muhammad Ali, Izabella Krystkowiak, Leandro Simonetti, Ahmed Sayadi, Filip Mihalic, Johanna Kliche, Eva Andersson, Per Jemth, Norman E Davey, Ylva Ivarsson
Mol Syst Biol. 2022 Jan; 18(1): e10584. Published online 2022 Jan 19. doi: 10.15252/msb.202110584
PMCID:
PMC8769072
AbstractArticlePDF–2.9M
6.
Structural insights into the activation initiation of full-length mGlu1
Jinyi Zhang, Lu Qu, Lijie Wu, Xiaomeng Tang, Feng Luo, Weixiu Xu, Yueming Xu, Zhi-Jie Liu, Tian Hua
Protein Cell. 2021 Aug; 12(8): 662–667. Published online 2020 Dec 5. doi: 10.1007/s13238-020-00808-5
PMCID:
PMC8310541
ArticlePDF–967K
7.
Metabotropic glutamate receptor 1 is associated with unfavorable prognosis in ER-negative and triple-negative breast cancer
Anna E. M. Bastiaansen, A. Mieke Timmermans, Marcel Smid, Carolien H. M. van Deurzen, Esther S. P. Hulsenboom, Wendy J. C. Prager-van der Smissen, Renée Foekens, Anita M. A. C. Trapman-Jansen, Peter A. E. Sillevis Smitt, Theo M. Luider, John W. M. Martens, Martijn M. vanDuijn
Sci Rep. 2020; 10: 22292. Published online 2020 Dec 18. doi: 10.1038/s41598-020-79248-4
PMCID:
PMC7749122
AbstractArticlePDF–1.7M
8.
Tamalin, a PDZ Domain-Containing Protein, Links a Protein Complex Formation of Group 1 Metabotropic Glutamate Receptors and the Guanine Nucleotide Exchange Factor Cytohesins
Jun Kitano, Kouji Kimura, Yoshimitsu Yamazaki, Takeshi Soda, Ryuichi Shigemoto, Yoshiaki Nakajima, Shigetada Nakanishi
J Neurosci. 2002 Feb 15; 22(4): 1280–1289. doi: 10.1523/JNEUROSCI.22-04-01280.2002
PMCID:
PMC6757580
AbstractArticlePDF–529K
9.
Developmental regulation of group I metabotropic glutamate receptors in the premature brain and their protective role in a rodent model of periventricular leukomalacia
LAUREN L. JANTZIE, DELIA M. TALOS, DEBRA B. SELIP, LI AN, MICHELE C. JACKSON, REBECCA D. FOLKERTH, WENBIN DENG, FRANCES E. JENSEN
Neuron Glia Biol. Author manuscript; available in PMC 2019 Sep 8.
Published in final edited form as: Neuron Glia Biol. 2010 Nov; 6(4): 277–288. Published online 2011 Dec 14. doi: 10.1017/S1740925X11000111
PMCID:
PMC6732218
AbstractArticlePDF–2.0M
10.
Interactions between Ephrin-B and Metabotropic Glutamate 1 Receptors in Brain Tissue and Cultured Neurons
L. Calò, V. Bruno, P. Spinsanti, G. Molinari, V. Korkhov, Z. Esposito, M. Patanè, D. Melchiorri, M. Freissmuth, F. Nicoletti
J Neurosci. 2005 Mar 2; 25(9): 2245–2254. doi: 10.1523/JNEUROSCI.4956-04.2005
PMCID:
PMC6726088
AbstractArticlePDF–519K
11.
Rab8 Modulates Metabotropic Glutamate Receptor Subtype 1 Intracellular Trafficking and Signaling in a Protein Kinase C-Dependent Manner
Jessica L. Esseltine, Fabiola M. Ribeiro, Stephen S. G. Ferguson
J Neurosci. 2012 Nov 21; 32(47): 16933–16942. doi: 10.1523/JNEUROSCI.0625-12.2012
PMCID:
PMC6621761
AbstractArticlePDF–1.8M
12.
Gain of additional BIRC3 protein functions through 3′UTR-mediated protein complex formation
Shih-Han Lee, Christine Mayr
Mol Cell. Author manuscript; available in PMC 2020 May 16.
Published in final edited form as: Mol Cell. 2019 May 16; 74(4): 701–712.e9. Published online 2019 Apr 1. doi: 10.1016/j.molcel.2019.03.006
PMCID:
PMC6581197
AbstractArticlePDF–2.0M
13.
Metabotropic glutamate receptor-1 regulates inflammation in triple negative breast cancer
Rachel E. Sexton, Ali H. Hachem, Ali A. Assi, Miriam A. Bukhsh, David H. Gorski, Cecilia L. Speyer
Sci Rep. 2018; 8: 16008. Published online 2018 Oct 30. doi: 10.1038/s41598-018-34502-8
PMCID:
PMC6207734
AbstractArticlePDF–1.9M
14.
Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei
Domenico Fasci, Hugo van Ingen, Richard A. Scheltema, Albert J. R. Heck
Mol Cell Proteomics. 2018 Oct; 17(10): 2018–2033. Published online 2018 Jul 18. doi: 10.1074/mcp.RA118.000924
PMCID:
PMC6166682
AbstractArticlePDF–3.8M
15.
An Essential Role of Fyn in the Modulation of Metabotropic Glutamate Receptor 1 in Neurons
Dao-Zhong Jin, Li-Min Mao, John Q. Wang
eNeuro. 2017 Jul-Aug; 4(4): ENEURO.0096-17.2017. Prepublished online 2017 Aug 24. Published online 2017 May 30. doi: 10.1523/ENEURO.0096-17.2017
PMCID:
PMC5608834
AbstractArticlePDF–2.0M
16.
Dominant Mutations in GRM1 Cause Spinocerebellar Ataxia Type 44
Lauren M. Watson, Elizabeth Bamber, Ricardo Parolin Schnekenberg, Jonathan Williams, Conceição Bettencourt, Jennifer Lickiss, Katherine Fawcett, Samuel Clokie, Yvonne Wallis, Penny Clouston, David Sims, Henry Houlden, Esther B.E. Becker, Andrea H. Németh
Am J Hum Genet. 2017 Sep 7; 101(3): 451–458. Published online 2017 Sep 7. doi: 10.1016/j.ajhg.2017.08.005
Correction in:
Am J Hum Genet. 2017 Oct 5; 101(4): 638.
Correction in:
Am J Hum Genet. 2017 Nov 2; 101(5): 866.
PMCID:
PMC5591020
AbstractArticlePDF–1.0M
17.
Systematic protein–protein interaction mapping for clinically relevant human GPCRs
Kate Sokolina, Saranya Kittanakom, Jamie Snider, Max Kotlyar, Pascal Maurice, Jorge Gandía, Abla Benleulmi‐Chaachoua, Kenjiro Tadagaki, Atsuro Oishi, Victoria Wong, Ramy H Malty, Viktor Deineko, Hiroyuki Aoki, Shahreen Amin, Zhong Yao, Xavier Morató, David Otasek, Hiroyuki Kobayashi, Javier Menendez, Daniel Auerbach, Stephane Angers, Natasa Pržulj, Michel Bouvier, Mohan Babu, Francisco Ciruela, Ralf Jockers, Igor Jurisica, Igor Stagljar
Mol Syst Biol. 2017 Mar; 13(3): 918. Published online 2017 Mar 15. doi: 10.15252/msb.20167430
PMCID:
PMC5371730
AbstractArticlePDF–4.1M
18.
The OncoPPi network of cancer-focused protein–protein interactions to inform biological insights and therapeutic strategies
Zenggang Li, Andrei A. Ivanov, Rina Su, Valentina Gonzalez-Pecchi, Qi Qi, Songlin Liu, Philip Webber, Elizabeth McMillan, Lauren Rusnak, Cau Pham, Xiaoqian Chen, Xiulei Mo, Brian Revennaugh, Wei Zhou, Adam Marcus, Sahar Harati, Xiang Chen, Margaret A. Johns, Michael A. White, Carlos S. Moreno, Lee A. D. Cooper, Yuhong Du, Fadlo R. Khuri, Haian Fu
Nat Commun. 2017; 8: 14356. Published online 2017 Feb 16. doi: 10.1038/ncomms14356
Correction in:
Nat Commun. 2017; 8: 15350.
PMCID:
PMC5316855
AbstractArticlePDF–4.1M
19.
Metabotropic glutamate receptor 1 disrupts mammary acinar architecture and initiates malignant transformation of mammary epithelial cells
Jessica L. F. Teh, Raj Shah, Stephanie La Cava, Sonia C. Dolfi, Madhura S. Mehta, Sameera Kongara, Sandy Price, Shridar Ganesan, Kenneth R. Reuhl, Kim M. Hirshfield, Vassiliki Karantza, Suzie Chen
Breast Cancer Res Treat. Author manuscript; available in PMC 2016 Dec 28.
Published in final edited form as: Breast Cancer Res Treat. 2015 May; 151(1): 57–73. Published online 2015 Apr 10. doi: 10.1007/s10549-015-3365-8
PMCID:
PMC5193007
AbstractArticlePDF–1.1M
20.
Are Type 1 metabotropic glutamate receptors a viable therapeutic target for the treatment of cerebellar ataxia?
Emmet M. Power, Natalya A. English, Ruth M. Empson
J Physiol. 2016 Aug 15; 594(16): 4643–4652. Published online 2016 Feb 24. doi: 10.1113/JP271153
PMCID:
PMC4983619
AbstractArticlePDF–631K

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