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Items: 1 to 20 of 58

1.
K48- and K63-linked ubiquitin chain interactome reveals branch- and length-specific ubiquitin interactors
Anita Waltho, Oliver Popp, Christopher Lenz, Lukas Pluska, Mahil Lambert, Volker Dötsch, Philipp Mertins, Thomas Sommer
Life Sci Alliance. 2024 Aug; 7(8): e202402740. Published online 2024 May 21. doi: 10.26508/lsa.202402740
PMCID:
PMC11109483
AbstractArticlePDF–2.9M
2.
De Novo Missense Mutations in TNNC1 and TNNI3 Causing Severe Infantile Cardiomyopathy Affect Myofilament Structure and Function and Are Modulated by Troponin Targeting Agents
Roua Hassoun, Heidi Budde, Hans Georg Mannherz, Mária Lódi, Setsuko Fujita-Becker, Kai Thorsten Laser, Anna Gärtner, Karin Klingel, Desirée Möhner, Robert Stehle, Innas Sultana, Thomas Schaaf, Mario Majchrzak, Verena Krause, Christian Herrmann, Marc M. Nowaczyk, Andreas Mügge, Gabriele Pfitzer, Rasmus R. Schröder, Nazha Hamdani, Hendrik Milting, Kornelia Jaquet, Diana Cimiotti
Int J Mol Sci. 2021 Sep; 22(17): 9625. Published online 2021 Sep 6. doi: 10.3390/ijms22179625
PMCID:
PMC8431798
AbstractArticlePDF–7.1M
3.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
4.
Binding of calcium and magnesium to human cardiac troponin C
Kaveh Rayani, Justin Seffernick, Alison Yueh Li, Jonathan P. Davis, Anne Marie Spuches, Filip Van Petegem, R. John Solaro, Steffen Lindert, Glen F. Tibbits
J Biol Chem. 2021 Jan-Jun; 296: 100350. Published online 2021 Feb 3. doi: 10.1016/j.jbc.2021.100350
PMCID:
PMC7961095
AbstractArticlePDF–2.3M
5.
Interpretation of elevated high-sensitivity cardiac troponin I in elite soccer players previously infected by severe acute respiratory syndrome coronavirus 2
Giuseppe Mascia, Fabio Pescetelli, Amedeo Baldari, Piero Gatto, Sara Seitun, Paolo Sartori, Maurizio Pieroni, Leonardo Calò, Roberta Della Bona, Italo Porto
Int J Cardiol. 2021 Mar 1; 326: 248–251. Published online 2020 Nov 23. doi: 10.1016/j.ijcard.2020.11.039
PMCID:
PMC7682525
AbstractArticlePDF–513K
6.
TNNC1 Reduced Gemcitabine Sensitivity of Nonsmall-Cell Lung Cancer by Increasing Autophagy
Xian Ye, Guanghui Xie, Zhijian Liu, Jun Tang, Mingyuan Cui, Chenbin Wang, Chi Guo, Jianfeng Tang
Med Sci Monit. 2020; 26: e922703-1–e922703-12. Prepublished online 2020 Jul 24. Published online 2020 Sep 18. doi: 10.12659/MSM.922703
PMCID:
PMC7523424
AbstractArticlePDF–1.7M
7.
Characterization of TNNC1 as a Novel Tumor Suppressor of Lung Adenocarcinoma
Suyeon Kim, Jaewon Kim, Yeonjoo Jung, Yukyung Jun, Yeonhwa Jung, Hee-Young Lee, Juhee Keum, Byung Jo Park, Jinseon Lee, Jhingook Kim, Sanghyuk Lee, Jaesang Kim
Mol Cells. 2020 Jul 31; 43(7): 619–631. Published online 2020 Jul 8. doi: 10.14348/molcells.2020.0075
PMCID:
PMC7398794
AbstractArticlePDF–1.8M
8.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
9.
Troponin C Mutations Partially Stabilize the Active State of Regulated Actin and Fully Stabilize the Active State When Paired with Δ14 TnT
Tamatha Baxley, Dylan Johnson, Jose R. Pinto, Joseph M. Chalovich
Biochemistry. Author manuscript; available in PMC 2019 Apr 4.
Published in final edited form as: Biochemistry. 2017 Jun 13; 56(23): 2928–2937. Published online 2017 May 31. doi: 10.1021/acs.biochem.6b01092
Correction in:
Biochemistry. 2017 Oct 24
PMCID:
PMC6448410
AbstractArticlePDF–816K
10.
Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains
Jean-Philippe Lambert, Sarah Picaud, Takao Fujisawa, Huayun Hou, Pavel Savitsky, Liis Uusküla-Reimand, Gagan D. Gupta, Hala Abdouni, Zhen-Yuan Lin, Monika Tucholska, James D.R. Knight, Beatriz Gonzalez-Badillo, Nicole St-Denis, Joseph A. Newman, Manuel Stucki, Laurence Pelletier, Nuno Bandeira, Michael D. Wilson, Panagis Filippakopoulos, Anne-Claude Gingras
Mol Cell. 2019 Feb 7; 73(3): 621–638.e17. doi: 10.1016/j.molcel.2018.11.006
PMCID:
PMC6375729
AbstractArticlePDF–10M
11.
Coarse-Grained Modeling of Peptide Docking Associated with Large Conformation Transitions of the Binding Protein: Troponin I Fragment–Troponin C System
Jacek Wabik, Mateusz Kurcinski, Andrzej Kolinski, Rino Ragno
Molecules. 2015 Jun; 20(6): 10763–10780. Published online 2015 Jun 11. doi: 10.3390/molecules200610763
PMCID:
PMC6272278
AbstractArticlePDF–6.0M
12.
Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei
Domenico Fasci, Hugo van Ingen, Richard A. Scheltema, Albert J. R. Heck
Mol Cell Proteomics. 2018 Oct; 17(10): 2018–2033. Published online 2018 Jul 18. doi: 10.1074/mcp.RA118.000924
PMCID:
PMC6166682
AbstractArticlePDF–3.8M
13.
LuTHy: a double‐readout bioluminescence‐based two‐hybrid technology for quantitative mapping of protein–protein interactions in mammalian cells
Philipp Trepte, Sabrina Kruse, Simona Kostova, Sheila Hoffmann, Alexander Buntru, Anne Tempelmeier, Christopher Secker, Lisa Diez, Aline Schulz, Konrad Klockmeier, Martina Zenkner, Sabrina Golusik, Kirstin Rau, Sigrid Schnoegl, Craig C Garner, Erich E Wanker
Mol Syst Biol. 2018 Jul; 14(7): e8071. Published online 2018 Jul 11. doi: 10.15252/msb.20178071
PMCID:
PMC6039870
AbstractArticlePDF–2.1M
14.
Changes in the dynamics of the cardiac troponin C molecule explain the effects of Ca2+-sensitizing mutations
Charles M. Stevens, Kaveh Rayani, Gurpreet Singh, Bairam Lotfalisalmasi, D. Peter Tieleman, Glen F. Tibbits
J Biol Chem. 2017 Jul 14; 292(28): 11915–11926. Published online 2017 May 22. doi: 10.1074/jbc.M116.770776
PMCID:
PMC5512083
AbstractArticlePDF–3.4M
15.
Use of the HEART Pathway with High Sensitivity Cardiac Troponins: A Secondary Analysis
Simon A. Mahler, Jason P. Stopyra, Fred S. Apple, Robert F. Riley, Gregory B. Russell, Brian C. Hiestand, James W. Hoekstra, Cedric W. Lefebvre, Bret A. Nicks, David M. Cline, Kim L. Askew, David M. Herrington, Gregory L. Burke, Chadwick D. Miller
Clin Biochem. Author manuscript; available in PMC 2018 May 1.
Published in final edited form as: Clin Biochem. 2017 May; 50(7-8): 401–407. Published online 2017 Jan 10. doi: 10.1016/j.clinbiochem.2017.01.003
PMCID:
PMC5446796
AbstractArticlePDF–765K
16.
MFAP5 and TNNC1: Potential markers for predicting occult cervical lymphatic metastasis and prognosis in early stage tongue cancer
Xi Yang, Kailiu Wu, Siyi Li, Longwei Hu, Jing Han, Dongwang Zhu, Xuerui Tian, Wei Liu, Zhen Tian, Laiping Zhong, Ming Yan, Chenping Zhang, Zhiyuan Zhang
Oncotarget. 2017 Jan 10; 8(2): 2525–2535. Published online 2016 Oct 4. doi: 10.18632/oncotarget.12446
PMCID:
PMC5356821
AbstractArticlePDF–4.3M
17.
Molecular Effects of cTnC DCM Mutations on Calcium Sensitivity and Myofilament Activation – An Integrated Multi-scale Modeling Study
Sukriti Dewan, Kimberly J. McCabe, Michael Regnier, Andrew D. McCulloch, Steffen Lindert
J Phys Chem B. Author manuscript; available in PMC 2017 Aug 25.
Published in final edited form as: J Phys Chem B. 2016 Aug 25; 120(33): 8264–8275. Published online 2016 May 6. doi: 10.1021/acs.jpcb.6b01950
PMCID:
PMC5001916
AbstractArticlePDF–2.0M
18.
Enhanced troponin I binding explains the functional changes produced by the hypertrophic cardiomyopathy mutation A8V of cardiac troponin C
Henry G. Zot, Javier E. Hasbun, Clara A. Michell, Maicon Landim-Vieira, Jose R. Pinto
Arch Biochem Biophys. Author manuscript; available in PMC 2017 Jul 1.
Published in final edited form as: Arch Biochem Biophys. 2016 Jul 1; 601: 97–104. Published online 2016 Mar 11. doi: 10.1016/j.abb.2016.03.011
PMCID:
PMC4899184
AbstractArticlePDF–610K
19.
The structural and functional effects of the familial hypertrophic cardiomyopathy-linked cardiac troponin C mutation, L29Q
Ian M. Robertson, Ivanka Sevrieva, Monica X. Li, Malcolm Irving, Yin-Biao Sun, Brian D. Sykes
J Mol Cell Cardiol. 2015 Oct; 87: 257–269. doi: 10.1016/j.yjmcc.2015.08.017
PMCID:
PMC4640586
AbstractArticlePDF–1.6M
20.
In vivo Analysis of Troponin C Knock-in (A8V) Mice: Evidence that TNNC1 Is a Hypertrophic Cardiomyopathy Susceptibility Gene
Adriano S. Martins, Michelle S. Parvatiyar, Han-Zhong Feng, J. Martijn Bos, David Gonzalez-Martinez, Milica Vukmirovic, Rajdeep S. Turna, Marcos A. Sanchez-Gonzalez, Crystal-Dawn Badger, Diego A. R. Zorio, Rakesh K. Singh, Yingcai Wang, J.-P. Jin, Michael J. Ackerman, Jose R. Pinto
Circ Cardiovasc Genet. Author manuscript; available in PMC 2016 Oct 1.
Published in final edited form as: Circ Cardiovasc Genet. 2015 Oct; 8(5): 653–664. Published online 2015 Aug 24. doi: 10.1161/CIRCGENETICS.114.000957
PMCID:
PMC4618104
AbstractArticlePDF–2.4M

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