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Items: 1 to 20 of 33

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
AMPK-Regulated Astrocytic Lactate Shuttle Plays a Non-Cell-Autonomous Role in Neuronal Survival
Ranjithmenon Muraleedharan, Mruniya V. Gawali, Durgesh Tiwari, Abitha Sukumaran, Nicole Oatman, Jane Anderson, Diana Nardini, Mohammad Alfrad Nobel Bhuiyan, Ivan Tkáč, Amber Lynne Ward, Mondira Kundu, Ronald Waclaw, Lionel M. Chow, Christina Gross, Raghavendra Rao, Stefanie Schirmeier, Biplab Dasgupta
Cell Rep. Author manuscript; available in PMC 2020 Oct 2.
Published in final edited form as: Cell Rep. 2020 Sep 1; 32(9): 108092. doi: 10.1016/j.celrep.2020.108092
PMCID:
PMC7531170
AbstractArticlePDF–4.3M
3.
BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING)
Kou Motani, Hidetaka Kosako
J Biol Chem. 2020 Aug 7; 295(32): 11174–11183. Published online 2020 Jun 17. doi: 10.1074/jbc.RA120.014323
PMCID:
PMC7415991
AbstractArticlePDF–2.0M
4.
New roles for the de-ubiquitylating enzyme OTUD4 in an RNA–protein network and RNA granules
Richa Das, Lukas Schwintzer, Stanislav Vinopal, Eva Aguado Roca, Marc Sylvester, Ana-Maria Oprisoreanu, Susanne Schoch, Frank Bradke, Meike Broemer
J Cell Sci. 2019 Jun 15; 132(12): jcs229252. Published online 2019 Jun 17. doi: 10.1242/jcs.229252
PMCID:
PMC6602300
AbstractArticle
5.
Autophagy is required for lung development and morphogenesis
Behzad Yeganeh, Joyce Lee, Leonardo Ermini, Irene Lok, Cameron Ackerley, Martin Post
J Clin Invest. 2019 Jul 1; 129(7): 2904–2919. Published online 2019 Jun 4. doi: 10.1172/JCI127307
PMCID:
PMC6597208
AbstractArticlePDF–24M
6.
AMP-activated protein kinase complexes containing the β2 regulatory subunit are up-regulated during and contribute to adipogenesis
Omar J. Katwan, Fatmah Alghamdi, Tarek A. Almabrouk, Sarah J. Mancini, Simon Kennedy, Jonathan S. Oakhill, John W. Scott, Ian P. Salt
Biochem J. 2019 Jun 28; 476(12): 1725–1740. Prepublished online 2019 Jun 12. Published online 2019 Jun 26. doi: 10.1042/BCJ20180714
PMCID:
PMC6595317
AbstractArticlePDF–4.4M
7.
AMP Kinase Promotes Glioblastoma Bioenergetics and Tumor Growth
Rishi Raj Chhipa, Qiang Fan, Jane Anderson, Ranjithmenon Muraleedharan, Yan Huang, Georgianne Ciraolo, Xiaoting Chen, Ronald Waclaw, Lionel M. Chow, Zaza Khuchua, Matthew Kofron, Matthew T. Weirauch, Ady Kendler, Christopher McPherson, Nancy Ratner, Ichiro Nakano, Nupur Dasgupta, Kakajan Komurov, Biplab Dasgupta
Nat Cell Biol. Author manuscript; available in PMC 2018 Dec 18.
Published in final edited form as: Nat Cell Biol. 2018 Jul; 20(7): 823–835. Published online 2018 Jun 18. doi: 10.1038/s41556-018-0126-z
PMCID:
PMC6113057
AbstractArticlePDF–4.6M
8.
CITGeneDB: a comprehensive database of human and mouse genes enhancing or suppressing cold-induced thermogenesis validated by perturbation experiments in mice
Jin Li, Su-Ping Deng, Gang Wei, Peng Yu
Database (Oxford) 2018; 2018: bay012. Published online 2018 Mar 23. doi: 10.1093/database/bay012
PMCID:
PMC5868181
AbstractArticlePDF–653K
9.
High-throughput discovery of novel developmental phenotypes
Mary E. Dickinson, Ann M. Flenniken, Xiao Ji, Lydia Teboul, Michael D. Wong, Jacqueline K. White, Terrence F. Meehan, Wolfgang J. Weninger, Henrik Westerberg, Hibret Adissu, Candice N. Baker, Lynette Bower, James M. Brown, L. Brianna Caddle, Francesco Chiani, Dave Clary, James Cleak, Mark J. Daly, James M. Denegre, Brendan Doe, Mary E. Dolan, Sarah M. Edie, Helmut Fuchs, Valerie Gailus-Durner, Antonella Galli, Alessia Gambadoro, Juan Gallegos, Shiying Guo, Neil R. Horner, Chih-wei Hsu, Sara J. Johnson, Sowmya Kalaga, Lance C. Keith, Louise Lanoue, Thomas N. Lawson, Monkol Lek, Manuel Mark, Susan Marschall, Jeremy Mason, Melissa L. McElwee, Susan Newbigging, Lauryl M.J. Nutter, Kevin A. Peterson, Ramiro Ramirez-Solis, Douglas J. Rowland, Edward Ryder, Kaitlin E. Samocha, John R. Seavitt, Mohammed Selloum, Zsombor Szoke-Kovacs, Masaru Tamura, Amanda G Trainor, Ilinca Tudose, Shigeharu Wakana, Jonathan Warren, Olivia Wendling, David B. West, Leeyean Wong, Atsushi Yoshiki, The International Mouse Phenotyping Consortium, Daniel G. MacArthur, Glauco P. Tocchini-Valentini, Xiang Gao, Paul Flicek, Allan Bradley, William C. Skarnes, Monica J. Justice, Helen E. Parkinson, Mark Moore, Sara Wells, Robert E. Braun, Karen L. Svenson, Martin Hrabe de Angelis, Yann Herault, Tim Mohun, Ann-Marie Mallon, R. Mark Henkelman, Steve D.M. Brown, David J. Adams, K.C. Kent Lloyd, Colin McKerlie, Arthur L. Beaudet, Maja Bucan, Stephen A. Murray
Nature. Author manuscript; available in PMC 2017 Mar 14.
Published in final edited form as: Nature. 2016 Sep 22; 537(7621): 508–514. Published online 2016 Sep 14. doi: 10.1038/nature19356
Correction in:
Nature. 2017 Nov 16; 551(7680): 398.
PMCID:
PMC5295821
AbstractArticlePDF–3.0M
10.
Lack of Adipocyte AMPK Exacerbates Insulin Resistance and Hepatic Steatosis through Brown and Beige Adipose Tissue Function
Emilio P. Mottillo, Eric M. Desjardins, Justin D. Crane, Brennan K. Smith, Alex E. Green, Serge Ducommun, Tora I. Henriksen, Irena A. Rebalka, Aida Razi, Kei Sakamoto, Camilla Scheele, Bruce E. Kemp, Thomas J. Hawke, Joaquin Ortega, James G. Granneman, Gregory R. Steinberg
Cell Metab. Author manuscript; available in PMC 2017 Jan 16.
Published in final edited form as: Cell Metab. 2016 Jul 12; 24(1): 118–129. doi: 10.1016/j.cmet.2016.06.006
PMCID:
PMC5239668
AbstractArticlePDF–1.8M
11.
AMPK Activation of Muscle Autophagy Prevents Fasting-Induced Hypoglycemia and Myopathy during Aging
Adam L. Bujak, Justin D. Crane, James S. Lally, Rebecca J. Ford, Sally J. Kang, Irena A. Rebalka, Alex E. Green, Bruce E. Kemp, Thomas J. Hawke, Jonathan D. Schertzer, Gregory R. Steinberg
Cell Metab. Author manuscript; available in PMC 2017 Jan 12.
Published in final edited form as: Cell Metab. 2015 Jun 2; 21(6): 883–890. doi: 10.1016/j.cmet.2015.05.016
PMCID:
PMC5233441
AbstractArticlePDF–1.1M
12.
Single phosphorylation sites in Acc1 and Acc2 regulate lipid homeostasis and the insulin–sensitizing effects of metformin
Morgan D. Fullerton, Sandra Galic, Katarina Marcinko, Sarah Sikkema, Thomas Pulinilkunnil, Zhi–Ping Chen, Hayley M. O’Neill, Rebecca J. Ford, Rengasamy Palanivel, Matthew O’Brien, D. Grahame Hardie, S. Lance Macaulay, Jonathan D. Schertzer, Jason R. B. Dyck, Bryce J. van Denderen, Bruce E. Kemp, Gregory R. Steinberg
Nat Med. Author manuscript; available in PMC 2016 Jul 28.
Published in final edited form as: Nat Med. 2013 Dec; 19(12): 1649–1654. Published online 2013 Nov 3. doi: 10.1038/nm.3372
PMCID:
PMC4965268
AbstractArticlePDF–938K
13.
Metformin Prevents Nigrostriatal Dopamine Degeneration Independent of AMPK Activation in Dopamine Neurons
Jacqueline A. Bayliss, Moyra B. Lemus, Vanessa V. Santos, Minh Deo, Jeffrey S. Davies, Bruce E. Kemp, John D. Elsworth, Zane B. Andrews
PLoS One. 2016; 11(7): e0159381. Published online 2016 Jul 28. doi: 10.1371/journal.pone.0159381
PMCID:
PMC4965122
AbstractArticlePDF–1.6M
14.
Ghrelin-AMPK Signaling Mediates the Neuroprotective Effects of Calorie Restriction in Parkinson's Disease
Jacqueline A. Bayliss, Moyra B. Lemus, Romana Stark, Vanessa V. Santos, Aiysha Thompson, Daniel J. Rees, Sandra Galic, John D. Elsworth, Bruce E. Kemp, Jeffrey S. Davies, Zane B. Andrews
J Neurosci. 2016 Mar 9; 36(10): 3049–3063. doi: 10.1523/JNEUROSCI.4373-15.2016
PMCID:
PMC4783502
AbstractArticlePDF–3.9M
15.
AMPK deficiency in cardiac muscle results in dilated cardiomyopathy in the absence of changes in energy metabolism
Miranda M. Sung, Beshay N. Zordoky, Adam L. Bujak, James S.V. Lally, David Fung, Martin E. Young, Sandrine Horman, Edward J. Miller, Peter E. Light, Bruce E. Kemp, Gregory R. Steinberg, Jason R.B. Dyck
Cardiovasc Res. 2015 Jul 15; 107(2): 235–245. Published online 2015 May 28. doi: 10.1093/cvr/cvv166
PMCID:
PMC4565988
AbstractArticlePDF–827K
16.
Metabolic regulator LKB1 plays a crucial role in Schwann cell-mediated axon maintenance
Bogdan Beirowski, Elisabetta Babetto, Judith P. Golden, Ying-Jr Chen, Kui Yang, Richard W. Gross, Gary J Patti, Jeffrey Milbrandt
Nat Neurosci. Author manuscript; available in PMC 2015 Jul 7.
Published in final edited form as: Nat Neurosci. 2014 Oct; 17(10): 1351–1361. Published online 2014 Sep 7. doi: 10.1038/nn.3809
PMCID:
PMC4494117
AbstractArticlePDF–1.5M
17.
Muscle-specific AMPK β1β2-null mice display a myopathy due to loss of capillary density in nonpostural muscles
Melissa M. Thomas, David C. Wang, Donna M. D'Souza, Matthew P. Krause, Andrew S. Layne, David S. Criswell, Hayley M. O'Neill, Michael K. Connor, Judy E. Anderson, Bruce E. Kemp, Gregory R. Steinberg, Thomas J. Hawke
FASEB J. 2014 May; 28(5): 2098–2107. doi: 10.1096/fj.13-238972
PMCID:
PMC3986832
AbstractArticle
18.
The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data
Gautier Koscielny, Gagarine Yaikhom, Vivek Iyer, Terrence F. Meehan, Hugh Morgan, Julian Atienza-Herrero, Andrew Blake, Chao-Kung Chen, Richard Easty, Armida Di Fenza, Tanja Fiegel, Mark Grifiths, Alan Horne, Natasha A. Karp, Natalja Kurbatova, Jeremy C. Mason, Peter Matthews, Darren J. Oakley, Asfand Qazi, Jack Regnart, Ahmad Retha, Luis A. Santos, Duncan J. Sneddon, Jonathan Warren, Henrik Westerberg, Robert J. Wilson, David G. Melvin, Damian Smedley, Steve D. M. Brown, Paul Flicek, William C. Skarnes, Ann-Marie Mallon, Helen Parkinson
Nucleic Acids Res. 2014 Jan 1; 42(Database issue): D802–D809. Published online 2013 Nov 3. doi: 10.1093/nar/gkt977
PMCID:
PMC3964955
AbstractArticlePDF–5.7M
19.
Deficiency of the RIIβ subunit of PKA affects locomotor activity and energy homeostasis in distinct neuronal populations
Ruimao Zheng, Linghai Yang, Maria A. Sikorski, Linda C. Enns, Traci A. Czyzyk, Warren C. Ladiges, G. Stanley McKnight
Proc Natl Acad Sci U S A. 2013 Apr 23; 110(17): E1631–E1640. Published online 2013 Apr 8. doi: 10.1073/pnas.1219542110
PMCID:
PMC3637730
AbstractArticlePDF–2.1M
20.
The AMPK β2 Subunit Is Required for Energy Homeostasis during Metabolic Stress
Biplab Dasgupta, Jeong Sun Ju, Yo Sasaki, Xiaona Liu, Su-Ryun Jung, Kazuhiko Higashida, Diana Lindquist, Jeffrey Milbrandt
Mol Cell Biol. 2012 Jul; 32(14): 2837–2848. doi: 10.1128/MCB.05853-11
PMCID:
PMC3416196
AbstractArticlePDF–2.4M

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