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Items: 1 to 20 of 64

1.
Altered molecular and cellular mechanisms in KIF5A-associated neurodegenerative or neurodevelopmental disorders
Marta Cozzi, Stefania Magri, Barbara Tedesco, Guglielmo Patelli, Veronica Ferrari, Elena Casarotto, Marta Chierichetti, Paola Pramaggiore, Laura Cornaggia, Margherita Piccolella, Mariarita Galbiati, Paola Rusmini, Valeria Crippa, Jessica Mandrioli, Davide Pareyson, Chiara Pisciotta, Stefano D’Arrigo, Antonia Ratti, Lorenzo Nanetti, Caterina Mariotti, Elisa Sarto, Viviana Pensato, Cinzia Gellera, Daniela Di Bella, Riccardo M. Cristofani, Franco Taroni, Angelo Poletti
Cell Death Dis. 2024 Sep; 15(9): 692. Published online 2024 Sep 27. doi: 10.1038/s41419-024-07096-5
PMCID:
PMC11437142
AbstractArticlePDF–5.6M
2.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
3.
Impaired motor unit recovery and maintenance in a knock-in mouse model of ALS-associated Kif5a variant
Kelly A. Rich, Megan G. Pino, Mehmet E. Yalvac, Ashley Fox, Hallie Harris, Maria H. H. Balch, W. David Arnold, Stephen J. Kolb
Neurobiol Dis. Author manuscript; available in PMC 2024 Feb 17.
Published in final edited form as: Neurobiol Dis. 2023 Jun 15; 182: 106148. Published online 2023 May 8. doi: 10.1016/j.nbd.2023.106148
PMCID:
PMC10874102
AbstractArticlePDF–1.6M
4.
Activation of TLR7-mediated autophagy increases epileptic susceptibility via reduced KIF5A-dependent GABAA receptor transport in a murine model
Jing Liu, Pingyang Ke, Haokun Guo, Juan Gu, Yan Liu, Xin Tian, Xuefeng Wang, Fei Xiao
Exp Mol Med. 2023 Jun; 55(6): 1159–1173. Published online 2023 Jun 1. doi: 10.1038/s12276-023-01000-5
PMCID:
PMC10317981
AbstractArticlePDF–5.9M
5.
An ALS‐associated KIF5A mutant forms oligomers and aggregates and induces neuronal toxicity
Juri Nakano, Kyoko Chiba, Shinsuke Niwa
Genes Cells. 2022 Jun; 27(6): 421–435. Published online 2022 May 20. doi: 10.1111/gtc.12936
PMCID:
PMC9322661
AbstractArticlePDF–4.7M
6.
Quantitative transportomics identifies Kif5a as a major regulator of neurodegeneration
Sahil H Shah, Lucio M Schiapparelli, Yuanhui Ma, Satoshi Yokota, Melissa Atkins, Xin Xia, Evan G Cameron, Thanh Huang, Sarah Saturday, Catalina B Sun, Cara Knasel, Seth Blackshaw, John R Yates, Hollis T Cline, Jeffrey L Goldberg
eLife. 2022; 11: e68148. Published online 2022 Mar 8. doi: 10.7554/eLife.68148
PMCID:
PMC8947766
AbstractArticlePDF–6.3M
7.
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development
Francesco Bedogni, Robert F. Hevner
Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034
PMCID:
PMC8313239
AbstractArticlePDF–1.6M
8.
KIF5A-dependent axonal transport deficiency disrupts autophagic flux in trimethyltin chloride-induced neurotoxicity
Mengyu Liu, Huifeng Pi, Yu Xi, Liting Wang, Li Tian, Mengyan Chen, Jia Xie, Ping Deng, Tao Zhang, Chao Zhou, Yidan Liang, Lei Zhang, Mindi He, Yonghui Lu, Chunhai Chen, Zhengping Yu, Zhou Zhou
Autophagy. 2021; 17(4): 903–924. Published online 2020 Mar 30. doi: 10.1080/15548627.2020.1739444
PMCID:
PMC8078766
AbstractArticlePDF–5.6M
9.
Normal levels of KIF5 but reduced KLC1 levels in both Alzheimer disease and Alzheimer disease in Down syndrome: evidence suggesting defects in anterograde transport
Xu-Qiao Chen, Utpal Das, Gooho Park, William C. Mobley
Alzheimers Res Ther. 2021; 13: 59. Published online 2021 Mar 10. doi: 10.1186/s13195-021-00796-6
PMCID:
PMC7945332
AbstractArticlePDF–2.9M
10.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
11.
Specific depletion of the motor protein KIF5B leads to deficits in dendritic transport, synaptic plasticity and memory
Junjun Zhao, Albert Hiu Ka Fok, Ruolin Fan, Pui-Yi Kwan, Hei-Lok Chan, Louisa Hoi-Ying Lo, Ying-Shing Chan, Wing-Ho Yung, Jiandong Huang, Cora Sau Wan Lai, Kwok-On Lai
eLife. 2020; 9: e53456. Published online 2020 Jan 21. doi: 10.7554/eLife.53456
PMCID:
PMC7028368
AbstractArticlePDF–5.0M
12.
Gene- and tissue-level interactions in normal gastrointestinal development and Hirschsprung disease
Sumantra Chatterjee, Priyanka Nandakumar, Dallas R. Auer, Stacey B. Gabriel, Aravinda Chakravarti
Proc Natl Acad Sci U S A. 2019 Dec 26; 116(52): 26697–26708. Published online 2019 Dec 9. doi: 10.1073/pnas.1908756116
PMCID:
PMC6936708
AbstractArticlePDF–2.1M
13.
Postsynaptic density protein 95 (PSD-95) is transported by KIF5 to dendritic regions
Ki-Seo Yoo, Kina Lee, Jun-Young Oh, Hyoeun Lee, Hyungju Park, Young Seok Park, Hyong Kyu Kim
Mol Brain. 2019; 12: 97. Published online 2019 Nov 21. doi: 10.1186/s13041-019-0520-x
PMCID:
PMC6873588
AbstractArticlePDF–3.6M
14.
KIF5C, a Novel Neuronal Kinesin Enriched in Motor Neurons
Yoshimitsu Kanai, Yasushi Okada, Yosuke Tanaka, Akihiro Harada, Sumio Terada, Nobutaka Hirokawa
J Neurosci. 2000 Sep 1; 20(17): 6374–6384. doi: 10.1523/JNEUROSCI.20-17-06374.2000
PMCID:
PMC6772948
AbstractArticlePDF–1.6M
15.
Identification of Quantitative Trait Loci That Affect Aggressive Behavior in Mice
Edward S. Brodkin, Sarah A. Goforth, Angela H. Keene, John A. Fossella, Lee M. Silver
J Neurosci. 2002 Feb 1; 22(3): 1165–1170. doi: 10.1523/JNEUROSCI.22-03-01165.2002
PMCID:
PMC6758516
AbstractArticlePDF–126K
16.
Kinesin-1 Proteins KIF5A, -5B, and -5C Promote Anterograde Transport of Herpes Simplex Virus Enveloped Virions in Axons
Grayson DuRaine, Todd W. Wisner, Paul Howard, David C. Johnson
J Virol. 2018 Oct 15; 92(20): e01269-18. Prepublished online 2018 Aug 1. Published online 2018 Sep 26. doi: 10.1128/JVI.01269-18
PMCID:
PMC6158419
AbstractArticlePDF–1.5M
17.
Spatio-temporal profile of postynaptic interactomes integrates components of complex brain disorders
Jing Li, Wangshu Zhang, Hui Yang, Daniel P. Howrigan, Brent Wilkinson, Tade Souaiaia, Oleg V. Evgrafov, Giulio Genovese, Veronica A. Clementel, Jennifer C. Tudor, Ted Abel, James A. Knowles, Benjamin M. Neale, Kai Wang, Fengzhu Sun, Marcelo P. Coba
Nat Neurosci. Author manuscript; available in PMC 2018 Aug 1.
Published in final edited form as: Nat Neurosci. 2017 Aug; 20(8): 1150–1161. Published online 2017 Jun 26. doi: 10.1038/nn.4594
PMCID:
PMC5645082
AbstractArticlePDF–2.3M
18.
Spatiotemporally Controlled Ablation of Klf5 Results in Dysregulated Epithelial Homeostasis in Adult Mouse Corneas
Chelsea L. Loughner, Anil Tiwari, Doreswamy Kenchegowda, Sudha Swamynathan, Shivalingappa K. Swamynathan
Invest Ophthalmol Vis Sci. 2017 Sep; 58(11): 4683–4693. doi: 10.1167/iovs.17-22498
PMCID:
PMC5598321
AbstractArticlePDF–3.0M
19.
KIF5A transports collagen vesicles of myofibroblasts during pleural fibrosis
Hirotoshi Kamata, Yoshikazu Tsukasaki, Tsuyoshi Sakai, Reiko Ikebe, Julia Wang, Ann Jeffers, Jake Boren, Shuzi Owens, Takahiro Suzuki, Masaaki Higashihara, Steven Idell, Torry A. Tucker, Mitsuo Ikebe
Sci Rep. 2017; 7: 4556. Published online 2017 Jul 4. doi: 10.1038/s41598-017-04437-7
PMCID:
PMC5496869
AbstractArticlePDF–2.3M
20.
Fancd2 in vivo interaction network reveals a non-canonical role in mitochondrial function
Tingting Zhang, Wei Du, Andrew F. Wilson, Satoshi H. Namekawa, Paul R. Andreassen, Amom Ruhikanta Meetei, Qishen Pang
Sci Rep. 2017; 7: 45626. Published online 2017 Apr 5. doi: 10.1038/srep45626
PMCID:
PMC5381226
AbstractArticlePDF–1.4M

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