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Items: 1 to 20 of 277

1.
TRPV4 Mediates Alveolar Epithelial Barrier Integrity and Induces ADAM10-Driven E-Cadherin Shedding
Lena Schaller, Thomas Gudermann, Alexander Dietrich
Cells. 2024 Oct; 13(20): 1717. Published online 2024 Oct 17. doi: 10.3390/cells13201717
PMCID:
PMC11506556
AbstractArticlePDF–2.2M
2.
Identification and Properties of TRPV4 Mutant Channels Present in Polycystic Kidney Disease Patients
Ana M Hernández-Vega, Itzel Llorente, Raúl Sánchez-Hernández, Yayoi Segura, Teresa Tusié-Luna, Luis E Morales-Buenrostro, Refugio García-Villegas, León D Islas, Tamara Rosenbaum
Function (Oxf) 2024; 5(5): zqae031. Published online 2024 Jun 13. doi: 10.1093/function/zqae031
PMCID:
PMC11384909
AbstractArticlePDF–1.0M
3.
Gain-of-function mutations of TRPV4 acting in endothelial cells drive blood-CNS barrier breakdown and motor neuron degeneration in mice
Jeremy M. Sullivan, Anna M. Bagnell, Jonathan Alevy, Elvia Mena Avila, Ljubica Mihaljević, Pamela C. Saavedra-Rivera, Lingling Kong, Jennifer S. Huh, Brett A. McCray, William H. Aisenberg, Aamir R. Zuberi, Laurent Bogdanik, Cathleen M. Lutz, Zhaozhu Qiu, Katharina A. Quinlan, Peter C. Searson, Charlotte J. Sumner
Sci Transl Med. Author manuscript; available in PMC 2024 Aug 10.
Published in final edited form as: Sci Transl Med. 2024 May 22; 16(748): eadk1358. Published online 2024 May 22. doi: 10.1126/scitranslmed.adk1358
PMCID:
PMC11316273
AbstractArticlePDF–2.3M
4.
Involvement of TRPV4 in temperature-dependent perspiration in mice
Makiko Kashio, Sandra Derouiche, Reiko U Yoshimoto, Kenji Sano, Jing Lei, Mizuho A Kido, Makoto Tominaga
eLife. 2024; 13: RP92993. Published online 2024 Jul 4. doi: 10.7554/eLife.92993
PMCID:
PMC11223765
AbstractArticlePDF–8.5M
5.
Independent endothelial functions of PIEZO1 and TRPV4 in hepatic portal vein and predominance of PIEZO1 in mechanical and osmotic stress
Naima Endesh, Eulashini Chuntharpursat‐Bon, Charlotte Revill, Nadira Y. Yuldasheva, T. Simon Futers, Gregory Parsonage, Neil Humphreys, Antony Adamson, Lara C. Morley, Richard M. Cubbon, K. Raj Prasad, Richard Foster, Laeticia Lichtenstein, David J. Beech
Liver Int. 2023 Sep; 43(9): 2026–2038. Published online 2023 Jun 22. doi: 10.1111/liv.15646
PMCID:
PMC10946873
AbstractArticlePDF–2.2M
6.
TRPV4 Channels Promote Pathological, but Not Physiological, Cardiac Remodeling through the Activation of Calcineurin/NFAT and TRPC6
Laia Yáñez-Bisbe, Mar Moya, Antonio Rodríguez-Sinovas, Marisol Ruiz-Meana, Javier Inserte, Marta Tajes, Montserrat Batlle, Eduard Guasch, Aleksandra Mas-Stachurska, Elisabet Miró, Nuria Rivas, Ignacio Ferreira González, Anna Garcia-Elias, Begoña Benito
Int J Mol Sci. 2024 Feb; 25(3): 1541. Published online 2024 Jan 26. doi: 10.3390/ijms25031541
PMCID:
PMC10855372
AbstractArticlePDF–3.7M
7.
Electroacupuncture ameliorates neuroinflammation by inhibiting TRPV4 channel in ischemic stroke
Xueqi Ren, Xinyi Gao, Ziqing Li, Yangyang Ding, Ao Xu, Lixia Du, Yufang Yang, Deheng Wang, Zhifei Wang, Shi Shu
CNS Neurosci Ther. 2024 Feb; 30(2): e14618. Published online 2024 Feb 9. doi: 10.1111/cns.14618
PMCID:
PMC10853892
AbstractArticlePDF–12M
8.
Transient Receptor Potential Vanilloid 4-Dependent Microglial Function in Myelin Injury and Repair
Jameson P. Holloman, Sophia H. Dimas, Angela S. Archambault, Fabia Filipello, Lixia Du, Jing Feng, Yonghui Zhao, Bryan Bollman, Laura Piccio, Andrew J. Steelman, Hongzhen Hu, Gregory F. Wu
Int J Mol Sci. 2023 Dec; 24(23): 17097. Published online 2023 Dec 4. doi: 10.3390/ijms242317097
PMCID:
PMC10706888
AbstractArticlePDF–2.9M
9.
Deletion of endothelial TRPV4 protects heart from pressure-overload-induced hypertrophy
Ravi K. Adapala, Venkatesh Katari, Anantha K. Kanugula, Vahagn Ohanyan, Sailaja Paruchuri, Charles K. Thodeti
Hypertension. Author manuscript; available in PMC 2024 Nov 1.
Published in final edited form as: Hypertension. 2023 Nov; 80(11): 2345–2356. Published online 2023 Sep 13. doi: 10.1161/HYPERTENSIONAHA.123.21528
PMCID:
PMC10705842
AbstractArticlePDF–3.1M
10.
Transient receptor potential vanilloid type 4 (TRPV4) in urinary bladder structure and function
Megan Elizabeth Perkins, Margaret A. Vizzard
Curr Top Membr. Author manuscript; available in PMC 2023 Sep 8.
Published in final edited form as: Curr Top Membr. 2022; 89: 95–138. Published online 2022 Jul 18. doi: 10.1016/bs.ctm.2022.06.002
PMCID:
PMC10486315
AbstractArticlePDF–1.9M
11.
Peripheral TRPV4 hypersensitivity contributes to chronic sickle cell disease pain
Vanessa L. Ehlers, Katelyn E. Sadler, Cheryl L. Stucky
Pain. Author manuscript; available in PMC 2024 Aug 1.
Published in final edited form as: Pain. 2023 Aug 1; 164(8): 1874–1886. Published online 2023 Mar 10. doi: 10.1097/j.pain.0000000000002889
PMCID:
PMC10363186
ArticlePDF–923K
12.
Silencing of TRPV4-expressing sensory neurons attenuates temporomandibular disorders pain
Fabiana C Dias, Zilong Wang, Garrett Scapellato, Yong Chen
Mol Pain. 2023; 19: 17448069231185696. Published online 2023 Jun 21. doi: 10.1177/17448069231185696
PMCID:
PMC10288408
AbstractArticlePDF–1015K
13.
TRPV4 expression in the renal tubule is necessary for maintaining whole body K+ homeostasis
Anna Stavniichuk, Kyrylo Pyrshev, Oleg Zaika, Viktor N. Tomilin, Mariya Kordysh, Monika Lakk, David Križaj, Oleh Pochynyuk
Am J Physiol Renal Physiol. 2023 Jun 1; 324(6): F603–F616. Published online 2023 May 4. doi: 10.1152/ajprenal.00278.2022
PMCID:
PMC10281785
AbstractArticle
14.
Sensory neuron-TRPV4 modulates temporomandibular disorder pain via CGRP in mice
Abbie Suttle, Peng Wang, Fabiana C. Dias, Qiaojuan Zhang, Yuhui Luo, Lauren Simmons, Andrey Bortsov, Inna E. Tchivileva, Andrea G. Nackley, Yong Chen
J Pain. Author manuscript; available in PMC 2024 May 1.
Published in final edited form as: J Pain. 2023 May; 24(5): 782–795. Published online 2022 Dec 9. doi: 10.1016/j.jpain.2022.12.001
PMCID:
PMC10164682
AbstractArticlePDF–1.5M
15.
The transient receptor potential vanilloid 4 (TRPV4) ion channel mediates protease activated receptor 1 (PAR1)-induced vascular hyperpermeability
Scott Peng, Megan S. Grace, Arisbel B. Gondin, Jeffri S. Retamal, Larissa Dill, William Darby, Nigel W. Bunnett, Fe C. Abogadie, Simona E. Carbone, Tara Tigani, Thomas P. Davis, Daniel P. Poole, Nicholas A. Veldhuis, Peter McIntyre
Lab Invest. Author manuscript; available in PMC 2023 Apr 7.
Published in final edited form as: Lab Invest. 2020 Aug; 100(8): 1057–1067. Published online 2020 Apr 27. doi: 10.1038/s41374-020-0430-7
PMCID:
PMC10080476
AbstractArticlePDF–2.2M
16.
TRPV4 channel is involved in HSV-2 infection in human vaginal epithelial cells through triggering Ca2+ oscillation
Ping Jiang, Song-shan Li, Xin-feng Xu, Chan Yang, Chen Cheng, Jin-shen Wang, Ping-zheng Zhou, Shu-wen Liu
Acta Pharmacol Sin. 2023 Apr; 44(4): 811–821. Published online 2022 Sep 23. doi: 10.1038/s41401-022-00975-7
PMCID:
PMC10042832
AbstractArticlePDF–2.9M
17.
Dental Pulp Stem Cell-Derived Exosomes Alleviate Mice Knee Osteoarthritis by Inhibiting TRPV4-Mediated Osteoclast Activation
Yu Fu, Shengjie Cui, Yanheng Zhou, Lixin Qiu
Int J Mol Sci. 2023 Mar; 24(5): 4926. Published online 2023 Mar 3. doi: 10.3390/ijms24054926
PMCID:
PMC10003468
AbstractArticlePDF–2.9M
18.
A TRPV4-dependent neuroimmune axis in the spinal cord promotes neuropathic pain
Xueming Hu, Lixia Du, Shenbin Liu, Zhou Lan, Kaikai Zang, Jing Feng, Yonghui Zhao, Xingliang Yang, Zili Xie, Peter L. Wang, Aaron M. Ver Heul, Lvyi Chen, Vijay K. Samineni, Yan-Qing Wang, Kory J. Lavine, Robert W. Gereau, IV, Gregory F. Wu, Hongzhen Hu
J Clin Invest. 2023 Mar 1; 133(5): e161507. Published online 2023 Mar 1. doi: 10.1172/JCI161507
PMCID:
PMC9974096
AbstractArticlePDF–12M
19.
TRPV4 ION Channel Is Associated with Scleroderma
Rishov Goswami, Jonathan Cohen, Shweta Sharma, David X. Zhang, Robert Lafyatis, Jag Bhawan, Shaik O. Rahaman
J Invest Dermatol. Author manuscript; available in PMC 2023 Feb 17.
Published in final edited form as: J Invest Dermatol. 2017 Apr; 137(4): 962–965. Published online 2016 Nov 23. doi: 10.1016/j.jid.2016.10.045
PMCID:
PMC9936819
ArticlePDF–736K
20.
Mechanoregulatory role of TRPV4 in prenatal skeletal development
Nidal S. Khatib, James Monsen, Saima Ahmed, Yuming Huang, David A. Hoey, Niamh C. Nowlan
Sci Adv. 2023 Jan; 9(4): eade2155. Published online 2023 Jan 25. doi: 10.1126/sciadv.ade2155
PMCID:
PMC9876556
AbstractArticlePDF–3.0M

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