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Items: 1 to 20 of 146

1.
Ehmt2 inactivation in pancreatic epithelial cells shapes the transcriptional landscape and inflammation response of the whole pancreas
Gareth Pollin, Angela J. Mathison, Thiago M. de Assuncao, Anju Thomas, Atefeh Zeighami, Ann Salmonson, Hongfei Liu, Guillermo Urrutia, Pallavi Vankayala, Stephen J. Pandol, Johnny C. Hong, Michael T. Zimmermann, Juan Iovanna, Victor X. Jin, Raul Urrutia, Gwen Lomberk
Front Genet. 2024; 15: 1412767. Published online 2024 Jun 14. doi: 10.3389/fgene.2024.1412767
PMCID:
PMC11211573
AbstractArticlePDF–6.1M
2.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
3.
G9a Inhibition Promotes Neuroprotection through GMFB Regulation in Alzheimer’s Disease
Aina Bellver-Sanchis, Qizhi Geng, Gemma Navarro, Pedro A. Ávila-López, Júlia Companys-Alemany, Laura Marsal-García, Raquel Larramona-Arcas, Lluisa Miró, Anna Perez-Bosque, Daniel Ortuño-Sahagún, Deb Ranjan Banerjee, Bhanwar Singh Choudhary, Francesc X Soriano, Coralie Poulard, Mercè Pallàs, Hai-Ning Du, Christian Griñán-Ferré
Aging Dis. 2024 Feb 1; 15(1): 311–337. Published online 2024 Feb 1. doi: 10.14336/AD.2023.0424-2
PMCID:
PMC10796087
AbstractArticlePDF–1.5M
4.
Loss of G9a does not phenocopy the requirement for Prdm12 in the development of the nociceptive neuron lineage
Panagiotis Tsimpos, Simon Desiderio, Pauline Cabochette, Philippe Poelvoorde, Sadia Kricha, Luc Vanhamme, Coralie Poulard, Eric J. Bellefroid
Neural Dev. 2024; 19: 1. Published online 2024 Jan 2. doi: 10.1186/s13064-023-00179-7
PMCID:
PMC10759634
AbstractArticlePDF–2.2M
5.
G9a and Sirtuin6 epigenetically modulate host cholesterol accumulation to facilitate mycobacterial survival
Praveen Prakhar, Bharat Bhatt, Gaurav Kumar Lohia, Awantika Shah, Tanushree Mukherjee, Ullas Kolthur-Seetharam, Nagalingam R. Sundaresan, Raju S. Rajmani, Kithiganahalli Narayanaswamy Balaji
PLoS Pathog. 2023 Oct; 19(10): e1011731. Published online 2023 Oct 23. doi: 10.1371/journal.ppat.1011731
PMCID:
PMC10621959
AbstractArticlePDF–2.7M
6.
Depletion of G9A attenuates imiquimod-induced psoriatic dermatitis via targeting EDAR-NF-κB signaling in keratinocyte
Zhiqin Fang, Yutong Wang, Bo Huang, Xiang Chen, Rundong Jiang, Mingzhu Yin
Cell Death Dis. 2023 Sep; 14(9): 627. Published online 2023 Sep 22. doi: 10.1038/s41419-023-06134-y
PMCID:
PMC10517171
AbstractArticlePDF–9.7M
7.
G9a promotes immune suppression by targeting the Fbxw7/Notch pathway in glioma stem cells
Yufei Cao, Bin Liu, Lize Cai, Yanyan Li, Yulun Huang, Youxin Zhou, Xingjian Sun, Wei Yang, Ting Sun
CNS Neurosci Ther. 2023 Sep; 29(9): 2508–2521. Published online 2023 Mar 27. doi: 10.1111/cns.14191
PMCID:
PMC10401078
AbstractArticlePDF–30M
8.
G9a inactivation in progenitor cells with Isl1-Cre with reduced recombinase activity models aspects of Dandy-Walker complex
Lijun Chi, Ling Zhong, Dorothy Lee, Xinwen Yu, Amalia Caballero, Brian Nieman, Paul Delgado-Olguin
Biol Open. 2023 Aug 15; 12(8): bio059894. Published online 2023 Jul 28. doi: 10.1242/bio.059894
PMCID:
PMC10399207
AbstractArticlePDF–7.8M
9.
Transcriptional coactivation by EHMT2 restricts glucocorticoid-induced insulin resistance in a study with male mice
Rebecca A. Lee, Maggie Chang, Nicholas Yiv, Ariel Tsay, Sharon Tian, Danielle Li, Coralie Poulard, Michael R. Stallcup, Miles A. Pufall, Jen-Chywan Wang
Nat Commun. 2023; 14: 3143. Published online 2023 May 30. doi: 10.1038/s41467-023-38584-5
PMCID:
PMC10229547
AbstractArticlePDF–2.0M
10.
G9a Modulates Lipid Metabolism in CD4 T Cells to Regulate Intestinal Inflammation
Guilherme Piovezani Ramos, Adebowale O. Bamidele, Emily E. Klatt, Mary R. Sagstetter, Ahmed T. Kurdi, Feda H. Hamdan, Robyn Laura Kosinsky, Joseph M. Gaballa, Asha Nair, Zhifu Sun, Surendra Dasari, Ian R. Lanza, Cody N. Rozeveld, Micah B. Schott, Guillermo Urrutia, Maria S. Westphal, Benjamin D. Clarkson, Charles L. Howe, Eric V. Marietta, David H. Luckey, Joseph A. Murray, Michelle Gonzalez, Manuel B. Braga Neto, Hunter R. Gibbons, Thomas C. Smyrk, Steven Johnsen, Gwen Lomberk, William A. Faubion
Gastroenterology. Author manuscript; available in PMC 2023 Feb 2.
Published in final edited form as: Gastroenterology. 2023 Feb; 164(2): 256–271.e10. Published online 2022 Oct 20. doi: 10.1053/j.gastro.2022.10.011
PMCID:
PMC9892272
AbstractArticlePDF–2.4M
11.
Large-Scale Functional Assessment of Genes Involved in Rare Diseases with Intellectual Disabilities Unravels Unique Developmental and Behaviour Profiles in Mouse Models
Hamid Meziane, Marie-Christine Birling, Olivia Wendling, Sophie Leblanc, Aline Dubos, Mohammed Selloum, Guillaume Pavlovic, Tania Sorg, Vera M. Kalscheuer, Pierre Billuart, Frédéric Laumonnier, Jamel Chelly, Hans van Bokhoven, Yann Herault
Biomedicines. 2022 Dec; 10(12): 3148. Published online 2022 Dec 6. doi: 10.3390/biomedicines10123148
PMCID:
PMC9775489
AbstractArticlePDF–2.8M
12.
Homocysteine facilitates endoplasmic reticulum stress and apoptosis of hepatocytes by suppressing ERO1α expression via cooperation between DNMT1 and G9a
Jiangyong Shen, Yun Jiao, Ning Ding, Lin Xie, Shengchao Ma, Hui Zhang, Anning Yang, Huiping Zhang, Yideng Jiang
Cell Biol Int. 2022 Aug; 46(8): 1236–1248. Published online 2022 Apr 14. doi: 10.1002/cbin.11805
PMCID:
PMC9543485
AbstractArticlePDF–3.2M
13.
EHMT2 methyltransferase governs cell identity in the lung and is required for KRAS G12D tumor development and propagation
Ariel Pribluda, Anneleen Daemen, Anthony Nelson Lima, Xi Wang, Marc Hafner, Chungkee Poon, Zora Modrusan, Anand Kumar Katakam, Oded Foreman, Jefferey Eastham, Jefferey Hung, Benjamin Haley, Julia T Garcia, Erica L Jackson, Melissa R Junttila
eLife. 2022; 11: e57648. Published online 2022 Aug 19. doi: 10.7554/eLife.57648
PMCID:
PMC9439681
AbstractArticlePDF–3.9M
14.
Cognitive Decline and BPSD Are Concomitant with Autophagic and Synaptic Deficits Associated with G9a Alterations in Aged SAMP8 Mice
Foteini Vasilopoulou, Aina Bellver-Sanchis, Júlia Companys-Alemany, Júlia Jarne-Ferrer, Alba Irisarri, Verónica Palomera-Ávalos, Celia Gonzalez-Castillo, Daniel Ortuño-Sahagún, Coral Sanfeliu, Mercè Pallàs, Christian Griñán-Ferré
Cells. 2022 Aug; 11(16): 2603. Published online 2022 Aug 21. doi: 10.3390/cells11162603
PMCID:
PMC9406492
AbstractArticlePDF–2.1M
15.
Keap1 moderates the transcription of virus induced genes through G9a-GLP and NFκB p50 recruitment
Veronica Elizabeth Burns, Tom Klaus Kerppola
Immunology. Author manuscript; available in PMC 2022 Sep 1.
Published in final edited form as: Immunology. 2022 Sep; 167(1): 105–121. Published online 2022 Jul 7. doi: 10.1111/imm.13527
PMCID:
PMC9378643
AbstractArticlePDF–3.2M
16.
Maternal EHMT2 is essential for homologous chromosome segregation by regulating Cyclin B3 transcription in oocyte meiosis
Tie-Gang Meng, Wen-Long Lei, Xukun Lu, Xiao-Yu Liu, Xue-Shan Ma, Xiao-Qing Nie, Zheng-Hui Zhao, Qian-Nan Li, Lin Huang, Yi Hou, Ying-Chun Ouyang, Lei Li, Tie-Shan Tang, Heide Schatten, Wei Xie, Shao-Rong Gao, Xiang-Hong Ou, Zhen-Bo Wang, Qing-Yuan Sun
Int J Biol Sci. 2022; 18(11): 4513–4531. Published online 2022 Jul 11. doi: 10.7150/ijbs.75298
PMCID:
PMC9295060
AbstractArticlePDF–2.7M
17.
Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1–CoREST interactome during embryonic stem cell differentiation
Claire E. Barnes, David M. English, Megan Broderick, Mark O. Collins, Shaun M. Cowley
Mol Omics. 2022 Jan 17; 18(1): 31–44. Published online 2021 Oct 14. doi: 10.1039/d1mo00236h
PMCID:
PMC8763317
AbstractArticle
18.
EHMT2 suppresses the variation of transcriptional switches in the mouse embryo
Tie-Bo Zeng, Nicholas Pierce, Ji Liao, Purnima Singh, Kin Lau, Wanding Zhou, Piroska E. Szabó
PLoS Genet. 2021 Nov; 17(11): e1009908. Published online 2021 Nov 18. doi: 10.1371/journal.pgen.1009908
PMCID:
PMC8601470
AbstractArticlePDF–6.1M
19.
Downregulation of a Dorsal Root Ganglion‐Specifically Enriched Long Noncoding RNA is Required for Neuropathic Pain by Negatively Regulating RALY‐Triggered Ehmt2 Expression
Zhiqiang Pan, Shibin Du, Kun Wang, Xinying Guo, Qingxiang Mao, Xiaozhou Feng, Lina Huang, Shaogen Wu, Bailing Hou, Yun‐Juan Chang, Tong Liu, Tong Chen, Hong Li, Thomas Bachmann, Alex Bekker, Huijuan Hu, Yuan‐Xiang Tao
Adv Sci (Weinh) 2021 Jul; 8(13): 2004515. Published online 2021 May 14. doi: 10.1002/advs.202004515
PMCID:
PMC8356248
AbstractArticlePDF–3.9M
20.
Identification of Jmjd3 as an Essential Epigenetic Regulator of Hox Gene Temporal Collinear Activation for Body Axial Patterning in Mice
Feng Zhang, Xiong Zhao, Runmin Jiang, Yuying Wang, Xinli Wang, Yu Gu, Longyong Xu, Jing Ye, Charlie Degui Chen, Shuangping Guo, Dawei Zhang, Daqing Zhao
Front Cell Dev Biol. 2021; 9: 642931. Published online 2021 Jul 21. doi: 10.3389/fcell.2021.642931
PMCID:
PMC8333871
AbstractArticlePDF–1.4M

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