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Items: 1 to 20 of 75

1.
Single-cell transcriptomics in MI identify Slc25a4 as a new modulator of mitochondrial malfunction and apoptosis-associated cardiomyocyte subcluster
Ting Zhou, Jing Pan, Kai Xu, Chenghui Yan, Jing Yuan, Haixu Song, Yaling Han
Sci Rep. 2024; 14: 9274. Published online 2024 Apr 23. doi: 10.1038/s41598-024-59975-8
PMCID:
PMC11039722
AbstractArticlePDF–13M
2.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
3.
The mitochondrially targeted peptide elamipretide (SS-31) improves ADP sensitivity in aged mitochondria by increasing uptake through the adenine nucleotide translocator (ANT)
Gavin Pharaoh, Varun Kamat, Sricharan Kannan, Rudolph S. Stuppard, Jeremy Whitson, Miguel Martín-Pérez, Wei-Jun Qian, Michael J. MacCoss, Judit Villén, Peter Rabinovitch, Matthew D. Campbell, Ian R. Sweet, David J. Marcinek
GeroScience. 2023 Dec; 45(6): 3529–3548. Published online 2023 Jul 18. doi: 10.1007/s11357-023-00861-y
PMCID:
PMC10643647
AbstractArticlePDF–1.8M
4.
ANT-dependent MPTP underlies necrotic myofiber death in muscular dystrophy
Michael J. Bround, Julian R. Havens, Allen J. York, Michelle A. Sargent, Jason Karch, Jeffery D. Molkentin
Sci Adv. 2023 Aug; 9(34): eadi2767. Published online 2023 Aug 25. doi: 10.1126/sciadv.adi2767
PMCID:
PMC10456852
AbstractArticlePDF–1.2M
5.
Mitochondrial protein import clogging as a mechanism of disease
Liam P Coyne, Xiaowen Wang, Jiyao Song, Ebbing de Jong, Karin Schneider, Paul T Massa, Frank A Middleton, Thomas Becker, Xin Jie Chen
eLife. 2023; 12: e84330. Published online 2023 May 2. doi: 10.7554/eLife.84330
PMCID:
PMC10208645
AbstractArticlePDF–12M
6.
Mitochondrial uncouplers induce proton leak by activating AAC and UCP1
Ambre M. Bertholet, Andrew M. Natale, Paola Bisignano, Junji Suzuki, Andriy Fedorenko, James Hamilton, Tatiana Brustovetsky, Lawrence Kazak, Ryan Garrity, Edward T. Chouchani, Nickolay Brustovetsky, Michael Grabe, Yuriy Kirichok
Nature. Author manuscript; available in PMC 2022 Dec 1.
Published in final edited form as: Nature. 2022 Jun; 606(7912): 180–187. Published online 2022 May 25. doi: 10.1038/s41586-022-04747-5
PMCID:
PMC9646675
AbstractArticlePDF–2.9M
7.
The Deubiquitinating Enzyme USP48 Interacts with the Retinal Degeneration-Associated Proteins UNC119a and ARL3
Laura Sánchez-Bellver, Andrea Férriz-Gordillo, Marc Carrillo-Pz, Laura Rabanal, Francesc R. Garcia-Gonzalo, Gemma Marfany
Int J Mol Sci. 2022 Oct; 23(20): 12527. Published online 2022 Oct 19. doi: 10.3390/ijms232012527
PMCID:
PMC9603860
AbstractArticlePDF–3.4M
8.
ALS-linked loss of Cyclin-F function affects HSP90
Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends
Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359
PMCID:
PMC9481933
AbstractArticlePDF–3.5M
9.
Nicotinamide riboside alleviates exercise intolerance in ANT1-deficient mice
Patrick M. Schaefer, Jessica Huang, Arrienne Butic, Caroline Perry, Tal Yardeni, Wendy Tan, Ryan Morrow, Joseph A. Baur, Douglas C. Wallace
Mol Metab. 2022 Oct; 64: 101560. Published online 2022 Aug 6. doi: 10.1016/j.molmet.2022.101560
PMCID:
PMC9411682
AbstractArticlePDF–2.7M
10.
ACAA2 is a Ligand-dependent Coactivator for Thyroid Hormone Receptor β1
Wesley Wang, Dolena Ledee
Biochem Biophys Res Commun. Author manuscript; available in PMC 2022 Oct 22.
Published in final edited form as: Biochem Biophys Res Commun. 2021 Oct 22; 576: 15–21. Published online 2021 Aug 28. doi: 10.1016/j.bbrc.2021.08.073
PMCID:
PMC8446338
AbstractArticlePDF–830K
11.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
12.
BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING)
Kou Motani, Hidetaka Kosako
J Biol Chem. 2020 Aug 7; 295(32): 11174–11183. Published online 2020 Jun 17. doi: 10.1074/jbc.RA120.014323
PMCID:
PMC7415991
AbstractArticlePDF–2.0M
13.
The ATP/ADP translocase drives mitophagy independent of nucleotide exchange
Atsushi Hoshino, Wei–jia Wang, Shogo Wada, Chris McDermott-Roe, Chantell S. Evans, Bridget Gosis, Michael P. Morley, Komal S. Rathi, Jian Li, Kristina Li, Steven Yang, Meagen J. McMannus, Caitlyn Bowman, Prasanth Potluri, Michael Levin, Scott Damrauer, Douglas C. Wallace, Erika L. F. Holzbaur, Zoltan Arany
Nature. Author manuscript; available in PMC 2020 Apr 16.
Published in final edited form as: Nature. 2019 Nov; 575(7782): 375–379. Published online 2019 Oct 16. doi: 10.1038/s41586-019-1667-4
PMCID:
PMC6858570
AbstractArticlePDF–3.2M
14.
Mitochondrial DNA Variation Dictates Expressivity and Progression of Nuclear DNA Mutations Causing Cardiomyopathy
Meagan J. McManus, Martin Picard, Hsiao-Wen Chen, Hans J. De Haas, Prasanth Potluri, Jeremy Leipzig, Atif Towheed, Alessia Angelin, Partho Sengupta, Ryan M. Morrow, Brett A. Kauffman, Marc Vermulst, Jagat Narula, Douglas C. Wallace
Cell Metab. Author manuscript; available in PMC 2019 Aug 31.
Published in final edited form as: Cell Metab. 2019 Jan 8; 29(1): 78–90.e5. Published online 2018 Aug 30. doi: 10.1016/j.cmet.2018.08.002
PMCID:
PMC6717513
AbstractArticlePDF–1.3M
15.
Inhibition of mitochondrial permeability transition by deletion of the ANT family and CypD
Jason Karch, Michael J. Bround, Hadi Khalil, Michelle A. Sargent, Nadina Latchman, Naohiro Terada, Pablo M. Peixoto, Jeffery D. Molkentin
Sci Adv. 2019 Aug; 5(8): eaaw4597. Published online 2019 Aug 28. doi: 10.1126/sciadv.aaw4597
PMCID:
PMC6713508
AbstractArticlePDF–1.4M
16.
The Interaction between Cell Adhesion Molecule L1, Matrix Metalloproteinase 14, and Adenine Nucleotide Translocator at the Plasma Membrane Regulates L1-Mediated Neurite Outgrowth of Murine Cerebellar Neurons
Gabriele Loers, Tatjana Makhina, Ute Bork, Andrea Dörner, Melitta Schachner, Ralf Kleene
J Neurosci. 2012 Mar 14; 32(11): 3917–3930. doi: 10.1523/JNEUROSCI.6165-11.2012
PMCID:
PMC6703462
AbstractArticlePDF–1.6M
17.
H+ Transport is an Integral Function of the Mitochondrial ADP/ATP Carrier
Ambre M. Bertholet, Edward T. Chouchani, Lawrence Kazak, Alessia Angelin, Andriy Fedorenko, Jonathan Z. Long, Sara Vidoni, Ryan Garrity, Joonseok Cho, Naohiro Terada, Douglas C. Wallace, Bruce M. Spiegelman, Yuriy Kirichok
Nature. Author manuscript; available in PMC 2020 Jan 24.
Published in final edited form as: Nature. 2019 Jul; 571(7766): 515–520. Published online 2019 Jul 24. doi: 10.1038/s41586-019-1400-3
PMCID:
PMC6662629
AbstractArticlePDF–4.5M
18.
Mouse screen reveals multiple new genes underlying mouse and human hearing loss
Neil J. Ingham, Selina A. Pearson, Valerie E. Vancollie, Victoria Rook, Morag A. Lewis, Jing Chen, Annalisa Buniello, Elisa Martelletti, Lorenzo Preite, Chi Chung Lam, Felix D. Weiss, Zӧe Powis, Pim Suwannarat, Christopher J. Lelliott, Sally J. Dawson, Jacqueline K. White, Karen P. Steel
PLoS Biol. 2019 Apr; 17(4): e3000194. Published online 2019 Apr 11. doi: 10.1371/journal.pbio.3000194
PMCID:
PMC6459510
AbstractArticlePDF–5.1M
19.
Plasticity in the Glucagon Interactome Reveals Novel Proteins That Regulate Glucagon Secretion in α-TC1-6 Cells
Farzad Asadi, Savita Dhanvantari
Front Endocrinol (Lausanne) 2018; 9: 792. Published online 2019 Jan 18. doi: 10.3389/fendo.2018.00792
PMCID:
PMC6346685
AbstractArticlePDF–3.6M
20.
Proteomic Analysis of the Spinophilin Interactome in Rodent Striatum Following Psychostimulant Sensitization
Darryl S. Watkins, Jason D. True, Amber L. Mosley, Anthony J. Baucum, II
Proteomes. 2018 Dec; 6(4): 53. Published online 2018 Dec 17. doi: 10.3390/proteomes6040053
Correction in:
Proteomes. 2019 Mar; 7(1): 7.
PMCID:
PMC6313900
AbstractArticlePDF–2.5M

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