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Items: 1 to 20 of 56

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Top-Down Proteomics of Mouse Islets With Beta Cell CPE Deletion Reveals Molecular Details in Prohormone Processing
James M Fulcher, Adam C Swensen, Yi-Chun Chen, C Bruce Verchere, Vladislav A Petyuk, Wei-Jun Qian
Endocrinology. 2023 Dec; 164(12): bqad160. Published online 2023 Nov 15. doi: 10.1210/endocr/bqad160
PMCID:
PMC10650973
AbstractArticle
3.
NEUROD1 reinforces endocrine cell fate acquisition in pancreatic development
Romana Bohuslavova, Valeria Fabriciova, Ondrej Smolik, Laura Lebrón-Mora, Pavel Abaffy, Sarka Benesova, Daniel Zucha, Lukas Valihrach, Zuzana Berkova, Frantisek Saudek, Gabriela Pavlinkova
Nat Commun. 2023; 14: 5554. Published online 2023 Sep 9. doi: 10.1038/s41467-023-41306-6
PMCID:
PMC10492842
AbstractArticlePDF–15M
4.
Casein kinase 1α is required to maintain murine hypothalamic pro-opiomelanocortin expression
Chenyang Lu, Jinglin Zhang, Bingjie Wang, Qiao Gao, Kezhe Ma, Shaona Pei, Juxue Li, Sheng Cui
iScience. 2023 May 19; 26(5): 106670. Published online 2023 Apr 14. doi: 10.1016/j.isci.2023.106670
PMCID:
PMC10165255
AbstractArticlePDF–8.2M
5.
Carboxypeptidase E conditional knockout mice exhibit learning and memory deficits and neurodegeneration
Fang-Cheng Fan, Yang Du, Wen-Hui Zheng, Y. Peng Loh, Yong Cheng
Transl Psychiatry. 2023; 13: 135. Published online 2023 Apr 26. doi: 10.1038/s41398-023-02429-y
PMCID:
PMC10133319
AbstractArticlePDF–3.9M
6.
Carboxypeptidase E Regulates Activity-Dependent TrkB Neuronal Surface Insertion and Hippocampal Memory
Na Li, Shuai-Wen Teng, Ling Zhao, Jing-Rui Li, Jia-Ling Xu, Na Li, Jia-Cheng Shuai, Zhe-Yu Chen
J Neurosci. 2021 Aug 18; 41(33): 6987–7002. doi: 10.1523/JNEUROSCI.0236-21.2021
PMCID:
PMC8372023
AbstractArticlePDF–4.7M
7.
Functional identity of hypothalamic melanocortin neurons depends on Tbx3
Carmelo Quarta, Alexandre Fisette, Yanjun Xu, Gustav Colldén, Beata Legutko, Yu-Ting Tseng, Alexander Reim, Michael Wierer, Maria C. De Rosa, Valentina Klaus, Rick Rausch, Vidhu V. Thaker, Elisabeth Graf, Tim M. Strom, Anne-Laure Poher, Tim Gruber, Ophélia Le Thuc, Alberto Cebrian-Serrano, Dhiraj Kabra, Luigi Bellocchio, Stephen C. Woods, Gert O. Pflugfelder, Rubén Nogueiras, Lori Zeltser, Ilona C. Grunwald Kadow, Anne Moon, Cristina García-Cáceres, Matthias Mann, Mathias Treier, Claudia A. Doege, Matthias H. Tschöp
Nat Metab. Author manuscript; available in PMC 2021 Jul 20.
Published in final edited form as: Nat Metab. 2019 Feb; 1(2): 222–235. Published online 2019 Jan 28. doi: 10.1038/s42255-018-0028-1
PMCID:
PMC8291379
AbstractArticlePDF–2.4M
8.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
9.
Neuropeptidomic analysis of a genetically-defined cell-type in mouse brain and pituitary
Lloyd D. Fricker, Alexandre K. Tashima, Amanda K. Fakira, Ute Hochgeschwender, William C. Wetsel, Lakshmi A. Devi
Cell Chem Biol. Author manuscript; available in PMC 2022 Jan 21.
Published in final edited form as: Cell Chem Biol. 2021 Jan 21; 28(1): 105–112.e4. Published online 2020 Nov 19. doi: 10.1016/j.chembiol.2020.11.003
PMCID:
PMC7856292
AbstractArticlePDF–666K
10.
Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant
Meagan A. Quinlan, Matthew J. Robson, Ran Ye, Kristie L. Rose, Kevin L. Schey, Randy D. Blakely
Front Mol Neurosci. 2020; 13: 89. Published online 2020 Jun 8. doi: 10.3389/fnmol.2020.00089
PMCID:
PMC7295033
AbstractArticlePDF–2.7M
11.
PC2/CPE-mediated pro-protein processing in tumor cells and its differentiated cells or tissues
Song-Shan Tang, Juan-Hui Zhang, Huan-Xin Liu, Hong-Zhi Li
Mol Cell Endocrinol. 2009 May 6; 303(1): 43–49. Published online 2009 Feb 7. doi: 10.1016/j.mce.2009.01.020
PMCID:
PMC7116944
AbstractArticlePDF–2.1M
12.
eIF4G1 and carboxypeptidase E axis dysregulation in O-GlcNAc transferase–deficient pancreatic β-cells contributes to hyperproinsulinemia in mice
Seokwon Jo, Amber Lockridge, Emilyn U. Alejandro
J Biol Chem. 2019 Aug 30; 294(35): 13040–13050. Published online 2019 Jul 12. doi: 10.1074/jbc.RA119.008670
PMCID:
PMC6721936
AbstractArticlePDF–2.9M
13.
Cloning, gene regulation, and neuronal proliferation functions of novel N-terminal–truncated carboxypeptidase E/neurotrophic factor-αl variants in embryonic mouse brain
Lan Xiao, Xuyu Yang, Vinay Kumar Sharma, Y. Peng Loh
FASEB J. 2019 Jan; 33(1): 808–820. Published online 2018 Jul 31. doi: 10.1096/fj.201800359R
PMCID:
PMC6355066
AbstractArticle
14.
Neurotrophic factor-α1: A key Wnt-β-catenin dependent anti-proliferation factor and ERK-Sox9 activated inducer of embryonic neural stem cell differentiation to astrocytes in neurodevelopment
Prabhuanand Selvaraj, Lan Xiao, Cheol Lee, Saravana R. K. Murthy, Niamh X. Cawley, Malcolm Lane, Istvan Merchenthaler, Sohyun Ahn, Y. Peng Loh
Stem Cells. Author manuscript; available in PMC 2018 Sep 10.
Published in final edited form as: Stem Cells. 2017 Mar; 35(3): 557–571. Published online 2016 Oct 26. doi: 10.1002/stem.2511
PMCID:
PMC6131007
AbstractArticlePDF–1006K
15.
Augmented Responses to Ozone in Obese Mice Require IL-17A and Gastrin-Releasing Peptide
Joel A. Mathews, Nandini Krishnamoorthy, David I. Kasahara, John Hutchinson, Youngji Cho, Jeffrey D. Brand, Alison S. Williams, Allison P. Wurmbrand, Luiza Ribeiro, Frank Cuttitta, Mary E. Sunday, Bruce D. Levy, Stephanie A. Shore
Am J Respir Cell Mol Biol. 2018 Mar; 58(3): 341–351. doi: 10.1165/rcmb.2017-0071OC
PMCID:
PMC5854955
AbstractArticlePDF–894K
16.
High-throughput discovery of novel developmental phenotypes
Mary E. Dickinson, Ann M. Flenniken, Xiao Ji, Lydia Teboul, Michael D. Wong, Jacqueline K. White, Terrence F. Meehan, Wolfgang J. Weninger, Henrik Westerberg, Hibret Adissu, Candice N. Baker, Lynette Bower, James M. Brown, L. Brianna Caddle, Francesco Chiani, Dave Clary, James Cleak, Mark J. Daly, James M. Denegre, Brendan Doe, Mary E. Dolan, Sarah M. Edie, Helmut Fuchs, Valerie Gailus-Durner, Antonella Galli, Alessia Gambadoro, Juan Gallegos, Shiying Guo, Neil R. Horner, Chih-wei Hsu, Sara J. Johnson, Sowmya Kalaga, Lance C. Keith, Louise Lanoue, Thomas N. Lawson, Monkol Lek, Manuel Mark, Susan Marschall, Jeremy Mason, Melissa L. McElwee, Susan Newbigging, Lauryl M.J. Nutter, Kevin A. Peterson, Ramiro Ramirez-Solis, Douglas J. Rowland, Edward Ryder, Kaitlin E. Samocha, John R. Seavitt, Mohammed Selloum, Zsombor Szoke-Kovacs, Masaru Tamura, Amanda G Trainor, Ilinca Tudose, Shigeharu Wakana, Jonathan Warren, Olivia Wendling, David B. West, Leeyean Wong, Atsushi Yoshiki, The International Mouse Phenotyping Consortium, Daniel G. MacArthur, Glauco P. Tocchini-Valentini, Xiang Gao, Paul Flicek, Allan Bradley, William C. Skarnes, Monica J. Justice, Helen E. Parkinson, Mark Moore, Sara Wells, Robert E. Braun, Karen L. Svenson, Martin Hrabe de Angelis, Yann Herault, Tim Mohun, Ann-Marie Mallon, R. Mark Henkelman, Steve D.M. Brown, David J. Adams, K.C. Kent Lloyd, Colin McKerlie, Arthur L. Beaudet, Maja Bucan, Stephen A. Murray
Nature. Author manuscript; available in PMC 2017 Mar 14.
Published in final edited form as: Nature. 2016 Sep 22; 537(7621): 508–514. Published online 2016 Sep 14. doi: 10.1038/nature19356
Correction in:
Nature. 2017 Nov 16; 551(7680): 398.
PMCID:
PMC5295821
AbstractArticlePDF–3.0M
17.
A Comparative Study of Lung Host Defense in Murine Obesity Models. Insights into Neutrophil Function
Niki D. J. Ubags, Elianne Burg, Maryellen Antkowiak, Aaron M. Wallace, Estee Dilli, Jenna Bement, Matthew J. Wargo, Matthew E. Poynter, Emiel F. M. Wouters, Benjamin T. Suratt
Am J Respir Cell Mol Biol. 2016 Aug; 55(2): 188–200. doi: 10.1165/rcmb.2016-0042OC
PMCID:
PMC4979371
AbstractArticlePDF–1.0M
18.
Carboxypeptidase E and Secretogranin III Coordinately Facilitate Efficient Sorting of Proopiomelanocortin to the Regulated Secretory Pathway in AtT20 Cells
Niamh X. Cawley, Trushar Rathod, Sigrid Young, Hong Lou, Nigel Birch, Y. Peng Loh
Mol Endocrinol. 2016 Jan; 30(1): 37–47. Published online 2015 Dec 8. doi: 10.1210/me.2015-1166
PMCID:
PMC4695627
AbstractArticle
19.
Innate and ozone-induced airway hyperresponsiveness in obese mice: role of TNF-α
Alison Suzanne Williams, Joel Andrew Mathews, David Itiro Kasahara, Allison Patricia Wurmbrand, Lucas Chen, Stephanie Ann Shore
Am J Physiol Lung Cell Mol Physiol. 2015 Jun 1; 308(11): L1168–L1177. Published online 2015 Apr 3. doi: 10.1152/ajplung.00393.2014
PMCID:
PMC4451401
AbstractArticle
20.
Neurotrophic Factor-a1 prevents stress-induced depression through enhancement of neurogenesis and is activated by rosiglitazone
Yong Cheng, Ramona M. Rodriguiz, Saravana R. K. Murthy, Vladimir Senatorov, Erwan Thouennon, Niamh X. Cawley, Dipendra K. Aryal, Sohyun Ahn, Beata Lecka-Czernik, William C. Wetsel, Y. Peng Loh
Mol Psychiatry. Author manuscript; available in PMC 2015 Dec 1.
Published in final edited form as: Mol Psychiatry. 2015 Jun; 20(6): 744–754. Published online 2014 Oct 21. doi: 10.1038/mp.2014.136
PMCID:
PMC4405386
AbstractArticlePDF–1.0M

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