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Select item 106059721.

Low m6A modification-mediated upregulation of PLAC8 promotes trophoblast cell invasion and migration in preeclampsia

Yajuan Zhang, Xiaoguang Guo, Zhimin Chen, Ruixia Guo

Eur J Med Res. 2023; 28: 466. Published online 2023 Oct 27. doi: 10.1186/s40001-023-01442-7

PMCID:: PMC10605972

Abstract Article PDF–1.8M

Select item 97726932.

Modification of PLAC8 by UFM1 affects tumorous proliferation and immune response by impacting PD-L1 levels in triple-negative breast cancer

Misha Mao, Yongxia Chen, Jingjing Yang, Yifan Cheng, Ling Xu, Feiyang Ji, Jichun Zhou, Xun Zhang, Zhaoqing Li, Cong Chen, Siwei Ju, Jiahang Zhang, Linbo Wang

J Immunother Cancer. 2022; 10(12): e005668. Published online 2022 Dec 21. doi: 10.1136/jitc-2022-005668

PMCID:: PMC9772693

Abstract Article PDF–30M

Select item 96276723.

Autophagy‐linked plasma and lysosomal membrane protein PLAC8 is a key host factor for SARS‐CoV‐2 entry into human cells

Alejandro P Ugalde, Gabriel Bretones, David Rodríguez, Víctor Quesada, Francisco Llorente, Raúl Fernández‐Delgado, Miguel Ángel Jiménez‐Clavero, Jesús Vázquez, Enrique Calvo, Isaac Tamargo‐Gómez, Guillermo Mariño, David Roiz‐Valle, Daniel Maeso, Miguel Araujo‐Voces, Yaiza Español, Carles Barceló, José MP Freije, Alejandro López‐Soto, Carlos López‐Otín

EMBO J. 2022 Nov; 41(21): e110727. Published online 2022 Oct 4. doi: 10.15252/embj.2022110727

PMCID:: PMC9627672

Abstract Article PDF–3.7M

Select item 90544854.

PLAC8 Overexpression Promotes Lung Cancer Cell Growth via Wnt/β-Catenin Signaling

Wei Chen, Junlu Wu, Weiwei Wang, Li Yu, Xianghuai Xu

J Immunol Res. 2022; 2022: 8854196. Published online 2022 Apr 22. doi: 10.1155/2022/8854196

PMCID:: PMC9054485

Abstract Article PDF–2.1M

Select item 82780875.

PLAC8 promotes adriamycin resistance via blocking autophagy in breast cancer

Yongxia Chen, Yunlu Jia, Misha Mao, Yifeng Gu, Chenpu Xu, Jingjing Yang, Wenxian Hu, Jun Shen, Dengdi Hu, Cong Chen, Zhaoqing Li, Lini Chen, Jian Ruan, Peng Shen, Jichun Zhou, Qun Wei, Linbo Wang

J Cell Mol Med. 2021 Jul; 25(14): 6948–6962. Published online 2021 Jun 11. doi: 10.1111/jcmm.16706

PMCID:: PMC8278087

Abstract Article PDF–3.0M

Select item 73481536.

Plac8‐mediated autophagy regulates nasopharyngeal carcinoma cell function via AKT/mTOR pathway

Mao‐Ling Huang, Cheng‐Lin Qi, You Zou, Rui Yang, Yang Jiang, Jian‐Fei Sheng, Yong‐Gang Kong, Ze‐Zhang Tao, Shi‐Ming Chen

J Cell Mol Med. 2020 Jul; 24(14): 7778–7788. Published online 2020 May 29. doi: 10.1111/jcmm.15409

PMCID:: PMC7348153

Abstract Article PDF–2.0M

Select item 71699837.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 69479368.

Expression pattern of placenta specific 8 and keratin 20 in different types of gastrointestinal cancer

Chih-Sheng Hung, Yen-Chieh Wang, Jiun-Wen Guo, Ruey-Neng Yang, Chia-Long Lee, Ming-Hung Shen, Chi-Cheng Huang, Chi-Jung Huang, Jhih-Yun Yang, Chih-Yi Liu

Mol Med Rep. 2020 Feb; 21(2): 659–666. Published online 2019 Dec 6. doi: 10.3892/mmr.2019.10871

PMCID:: PMC6947936

Abstract Article PDF–955K

Select item 67875009.

PLCA8 suppresses breast cancer apoptosis by activating the PI3k/AKT/NF‐κB pathway

Misha Mao, Yongxia Chen, Yunlu Jia, Jingjing Yang, Qun Wei, Zhaoqing Li, Lini Chen, Cong Chen, Linbo Wang

J Cell Mol Med. 2019 Oct; 23(10): 6930–6941. Published online 2019 Aug 26. doi: 10.1111/jcmm.14578

PMCID:: PMC6787500

Abstract Article PDF–2.0M

Select item 596412110.

The novel KLF4/PLAC8 signaling pathway regulates lung cancer growth

Yunlu Jia, Xiaogang Ying, Jichun Zhou, Yongxia Chen, Xiao Luo, Shudu Xie, Qin chuan Wang, Wenxian Hu, Linbo Wang

Cell Death Dis. 2018 Jun; 9(6): 603. Published online 2018 May 22. doi: 10.1038/s41419-018-0580-3

PMCID:: PMC5964121

Abstract Article PDF–2.5M

Select item 582583811.

PLAC8, a new marker for human interstitial extravillous trophoblast cells, promotes their invasion and migration

Wen-Lin Chang, Ya-Wei Liu, Yan-Li Dang, Xiang-Xiang Jiang, Honglin Xu, Xing Huang, Yan-Ling Wang, Haibin Wang, Cheng Zhu, Li-Qun Xue, Hai-Yan Lin, Wenxiang Meng, Hongmei Wang

Development. 2018 Jan 15; 145(2): dev148932. doi: 10.1242/dev.148932

PMCID:: PMC5825838

Abstract Article

Select item 484876212.

Pooled‐matrix protein interaction screens using Barcode Fusion Genetics

Nozomu Yachie, Evangelia Petsalaki, Joseph C Mellor, Jochen Weile, Yves Jacob, Marta Verby, Sedide B Ozturk, Siyang Li, Atina G Cote, Roberto Mosca, Jennifer J Knapp, Minjeong Ko, Analyn Yu, Marinella Gebbia, Nidhi Sahni, Song Yi, Tanya Tyagi, Dayag Sheykhkarimli, Jonathan F Roth, Cassandra Wong, Louai Musa, Jamie Snider, Yi‐Chun Liu, Haiyuan Yu, Pascal Braun, Igor Stagljar, Tong Hao, Michael A Calderwood, Laurence Pelletier, Patrick Aloy, David E Hill, Marc Vidal, Frederick P Roth

Mol Syst Biol. 2016 Apr; 12(4): 863. Published online 2016 Apr 23. doi: 10.15252/msb.20156660

PMCID:: PMC4848762

Abstract Article PDF–2.8M

Select item 447735313.

Epigenetic Regulation of Placenta-Specific 8 Contributes to Altered Function of Endothelial Colony-Forming Cells Exposed to Intrauterine Gestational Diabetes Mellitus

Emily K. Blue, BreAnn M. Sheehan, Zia V. Nuss, Frances A. Boyle, Caleb M. Hocutt, Cassandra R. Gohn, Kaela M. Varberg, Jeanette N. McClintick, Laura S. Haneline

Diabetes. 2015 Jul; 64(7): 2664–2675. Published online 2015 Feb 26. doi: 10.2337/db14-1709

PMCID:: PMC4477353

Abstract Article PDF–1.4M

Select item 426658814.

A proteome-scale map of the human interactome network

Thomas Rolland, Murat Taşan, Benoit Charloteaux, Samuel J. Pevzner, Quan Zhong, Nidhi Sahni, Song Yi, Irma Lemmens, Celia Fontanillo, Roberto Mosca, Atanas Kamburov, Susan D. Ghiassian, Xinping Yang, Lila Ghamsari, Dawit Balcha, Bridget E. Begg, Pascal Braun, Marc Brehme, Martin P. Broly, Anne-Ruxandra Carvunis, Dan Convery-Zupan, Roser Corominas, Jasmin Coulombe-Huntington, Elizabeth Dann, Matija Dreze, Amélie Dricot, Changyu Fan, Eric Franzosa, Fana Gebreab, Bryan J. Gutierrez, Madeleine F. Hardy, Mike Jin, Shuli Kang, Ruth Kiros, Guan Ning Lin, Katja Luck, Andrew MacWilliams, Jörg Menche, Ryan R. Murray, Alexandre Palagi, Matthew M. Poulin, Xavier Rambout, John Rasla, Patrick Reichert, Viviana Romero, Elien Ruyssinck, Julie M. Sahalie, Annemarie Scholz, Akash A. Shah, Amitabh Sharma, Yun Shen, Kerstin Spirohn, Stanley Tam, Alexander O. Tejeda, Shelly A. Wanamaker, Jean-Claude Twizere, Kerwin Vega, Jennifer Walsh, Michael E. Cusick, Yu Xia, Albert-László Barabási, Lilia M. Iakoucheva, Patrick Aloy, Javier De Las Rivas, Jan Tavernier, Michael A. Calderwood, David E. Hill, Tong Hao, Frederick P. Roth, Marc Vidal

Cell. Author manuscript; available in PMC 2015 Nov 20.

Published in final edited form as: Cell. 2014 Nov 20; 159(5): 1212–1226. doi: 10.1016/j.cell.2014.10.050

PMCID:: PMC4266588

Abstract Article PDF–3.1M

Select item 411257515.

Plac8 links oncogenic mutations to regulation of autophagy and is critical to pancreatic cancer progression

Conan Kinsey, Vijaya Balakrishnan, Michael R. O’Dell, Jing Li Huang, Laurel Newman, Christa L. Whitney-Miller, Aram F. Hezel, Hartmut Land

Cell Rep. Author manuscript; available in PMC 2015 May 22.

Published in final edited form as: Cell Rep. 2014 May 22; 7(4): 1143–1155. Published online 2014 May 1. doi: 10.1016/j.celrep.2014.03.061

PMCID:: PMC4112575

Abstract Article PDF–1.4M

Select item 400153616.

Excess PLAC8 promotes an unconventional ERK2-dependent EMT in colon cancer

Cunxi Li, Haiting Ma, Yang Wang, Zheng Cao, Ramona Graves-Deal, Anne E. Powell, Alina Starchenko, Gregory D. Ayers, Mary Kay Washington, Vidya Kamath, Keyur Desai, Michael J. Gerdes, Lila Solnica-Krezel, Robert J. Coffey

J Clin Invest. 2014 May 1; 124(5): 2172–2187. Published online 2014 Apr 1. doi: 10.1172/JCI71103

PMCID:: PMC4001536

Abstract Article PDF–10M

Select item 377558017.

Induction of retinol-binding protein 4 and placenta-specific 8 expression in human prostate cancer cells remaining in bone following osteolytic tumor growth inhibition by osteoprotegerin

HISANORI UEHARA, TETSUYUKI TAKAHASHI, KEISUKE IZUMI

Int J Oncol. 2013 Aug; 43(2): 365–374. Published online 2013 May 24. doi: 10.3892/ijo.2013.1954

PMCID:: PMC3775580

Abstract Article PDF–587K

Select item 352727618.

A Synthetic Interaction Screen Identifies Factors Selectively Required for Proliferation and TERT Transcription in p53-Deficient Human Cancer Cells

Li Xie, Claude Gazin, Sung Mi Park, Lihua J. Zhu, Marie-anne Debily, Ellen L. W. Kittler, Maria L. Zapp, David Lapointe, Stephane Gobeil, Ching-Man Virbasius, Michael R. Green

PLoS Genet. 2012 Dec; 8(12): e1003151. Published online 2012 Dec 20. doi: 10.1371/journal.pgen.1003151

PMCID:: PMC3527276

Abstract Article PDF–1.8M

Select item 317805919.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 268304720.

Ubiquitin-mediated proteolysis of HuR by heat shock

Kotb Abdelmohsen, Subramanya Srikantan, Xiaoling Yang, Ashish Lal, Hyeon Ho Kim, Yuki Kuwano, Stefanie Galban, Kevin G Becker, Davida Kamara, Rafael de Cabo, Myriam Gorospe

EMBO J. 2009 May 6; 28(9): 1271–1282. Published online 2009 Mar 26. doi: 10.1038/emboj.2009.67

PMCID:: PMC2683047

Abstract Article PDF–1.4M

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