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Select item 111094831.

K48- and K63-linked ubiquitin chain interactome reveals branch- and length-specific ubiquitin interactors

Anita Waltho, Oliver Popp, Christopher Lenz, Lukas Pluska, Mahil Lambert, Volker Dötsch, Philipp Mertins, Thomas Sommer

Life Sci Alliance. 2024 Aug; 7(8): e202402740. Published online 2024 May 21. doi: 10.26508/lsa.202402740

PMCID:: PMC11109483

Abstract Article PDF–2.9M

Select item 102374222.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 101427523.

Microglial CD68 and L-ferritin upregulation in response to phosphorylated-TDP-43 pathology in the amyotrophic lateral sclerosis brain

Molly E. V. Swanson, Miran Mrkela, Helen C. Murray, Maize C. Cao, Clinton Turner, Maurice A. Curtis, Richard L. M. Faull, Adam K. Walker, Emma L. Scotter

Acta Neuropathol Commun. 2023; 11: 69. Published online 2023 Apr 28. doi: 10.1186/s40478-023-01561-6

PMCID:: PMC10142752

Abstract Article PDF–12M

Select item 97725584.

HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation

Jingsheng Yuan, Tao Lv, Jian Yang, Zhenru Wu, Lvnan Yan, Jiayin Yang, Yujun Shi, Li Jiang

Cell Mol Gastroenterol Hepatol. 2023; 15(2): 307–325. Published online 2022 Oct 14. doi: 10.1016/j.jcmgh.2022.10.005

PMCID:: PMC9772558

Abstract Article PDF–8.2M

Select item 97061705.

Ferritin light chain deficiency-induced ferroptosis is involved in preeclampsia pathophysiology by disturbing uterine spiral artery remodelling

Xiaofeng Yang, Yuzhen Ding, Lu Sun, Meiting Shi, Ping Zhang, Zhengrui Huang, Jingyun Wang, Andong He, Jian Wang, Jiachun Wei, Mengyuan Liu, Jia Liu, Guang Wang, Xuesong Yang, Ruiman Li

Redox Biol. 2022 Dec; 58: 102555. Published online 2022 Nov 24. doi: 10.1016/j.redox.2022.102555

PMCID:: PMC9706170

Abstract Article PDF–16M

Select item 92792856.

Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery

Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili

Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z

PMCID:: PMC9279285

Abstract Article PDF–2.5M

Select item 88288957.

Human transcription factor protein interaction networks

Helka Göös, Matias Kinnunen, Kari Salokas, Zenglai Tan, Xiaonan Liu, Leena Yadav, Qin Zhang, Gong-Hong Wei, Markku Varjosalo

Nat Commun. 2022; 13: 766. Published online 2022 Feb 9. doi: 10.1038/s41467-022-28341-5

PMCID:: PMC8828895

Abstract Article PDF–1.7M

Select item 87489588.

EZH2 depletion potentiates MYC degradation inhibiting neuroblastoma and small cell carcinoma tumor formation

Liyuan Wang, Chan Chen, Zemin Song, Honghong Wang, Minghui Ye, Donghai Wang, Wenqian Kang, Hudan Liu, Guoliang Qing

Nat Commun. 2022; 13: 12. Published online 2022 Jan 10. doi: 10.1038/s41467-021-27609-6

PMCID:: PMC8748958

Abstract Article PDF–3.0M

Select item 87020989.

Longitudinal CSF Iron Pathway Proteins in Posthemorrhagic Hydrocephalus: Associations with Ventricle Size and Neurodevelopmental Outcomes

Jennifer M. Strahle, Kelly B. Mahaney, Diego M. Morales, Chandana Buddhala, Chevis N. Shannon, John C. Wellons, III, Abhaya V. Kulkarni, Hailey Jensen, Ron W. Reeder, Richard Holubkov, Jay K. Riva-Cambrin, William E. Whitehead, Curtis J. Rozzelle, Mandeep Tamber, Ian F. Pollack, Robert P. Naftel, John R.W. Kestle, David D. Limbrick, Jr., Hydrocephalus Clinical Research Network

Ann Neurol. Author manuscript; available in PMC 2022 Aug 1.

Published in final edited form as: Ann Neurol. 2021 Aug; 90(2): 217–226. Published online 2021 Jun 25. doi: 10.1002/ana.26133

PMCID:: PMC8702098

Abstract Article PDF–733K

Select item 866704910.

CD63 is regulated by iron via the IRE-IRP system and is important for ferritin secretion by extracellular vesicles

Izumi Yanatori, Des R. Richardson, Herschel S. Dhekne, Shinya Toyokuni, Fumio Kishi

Blood. 2021 Oct 21; 138(16): 1490–1503. doi: 10.1182/blood.2021010995

PMCID:: PMC8667049

Abstract Article

Select item 844875411.

Cigarette smoke extract and heated tobacco products promote ferritin cleavage and iron accumulation in human corneal epithelial cells

Wataru Otsu, Kodai Ishida, Naoki Chinen, Shinsuke Nakamura, Masamitsu Shimazawa, Hideshi Tsusaki, Hideaki Hara

Sci Rep. 2021; 11: 18555. Published online 2021 Sep 17. doi: 10.1038/s41598-021-97956-3

PMCID:: PMC8448754

Abstract Article PDF–6.6M

Select item 816503012.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 810906513.

Comprehensive analysis of ferritin subunits expression and positive correlations with tumor-associated macrophages and T regulatory cells infiltration in most solid tumors

Zhang-Wei Hu, Lin Chen, Ren-Qiang Ma, Fan-Qin Wei, Yi-Hui Wen, Xue-Lan Zeng, Wei Sun, Wei-Ping Wen

Aging (Albany NY) 2021 Apr 30; 13(8): 11491–11506. Published online 2021 Apr 16. doi: 10.18632/aging.202841

PMCID:: PMC8109065

Abstract Article PDF–3.0M

Select item 796824114.

Sialic acid-engineered mesoporous polydopamine dual loaded with ferritin gene and SPIO for achieving endogenous and exogenous synergistic T2-weighted magnetic resonance imaging of HCC

Kai Fan, Chengying Lu, Gaofeng Shu, Xiu-Ling Lv, Enqi Qiao, Nannan Zhang, Minjiang Chen, Jingjing Song, Fazong Wu, Zhongwei Zhao, Xiaoling Xu, Min Xu, Chunmiao Chen, Weibin Yang, Jihong Sun, Yongzhong Du, Jiansong Ji

J Nanobiotechnology. 2021; 19: 76. Published online 2021 Mar 17. doi: 10.1186/s12951-021-00821-8

PMCID:: PMC7968241

Abstract Article PDF–4.4M

Select item 789154115.

Ferritin as a key risk factor for nonalcoholic fatty liver disease in children with obesity

Junfeng Zhang, Jiajia Cao, Hui Xu, Guanping Dong, Ke Huang, Wei Wu, Jingjing Ye, Junfen Fu

J Clin Lab Anal. 2021 Feb; 35(2): e23602. Published online 2020 Nov 28. doi: 10.1002/jcla.23602

PMCID:: PMC7891541

Abstract Article PDF–312K

Select item 761053516.

PROTAC-mediated degradation reveals a non-catalytic function of AURORA-A kinase

Bikash Adhikari, Jelena Bozilovic, Mathias Diebold, Jessica Denise Schwarz, Julia Hofstetter, Martin Schröder, Marek Wanior, Ashwin Narain, Markus Vogt, Nevenka Dudvarski Stankovic, Apoorva Baluapuri, Lars Schönemann, Lorenz Eing, Pranjali Bhandare, Bernhard Kuster, Andreas Schlosser, Stephanie Heinzlmeir, Christoph Sotriffer, Stefan Knapp, Elmar Wolf

Nat Chem Biol. Author manuscript; available in PMC 2021 Apr 6.

Published in final edited form as: Nat Chem Biol. 2020 Nov 1; 16(11): 1179–1188. Published online 2020 Sep 28. doi: 10.1038/s41589-020-00652-y

PMCID:: PMC7610535

Abstract Article PDF–5.1M

Select item 756688117.

Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism

Michael Aregger, Keith A. Lawson, Maximillian Billmann, Michael Costanzo, Amy H. Y. Tong, Katherine Chan, Mahfuzur Rahman, Kevin R. Brown, Catherine Ross, Matej Usaj, Lucy Nedyalkova, Olga Sizova, Andrea Habsid, Judy Pawling, Zhen-Yuan Lin, Hala Abdouni, Cassandra J. Wong, Alexander Weiss, Patricia Mero, James W. Dennis, Anne-Claude Gingras, Chad L. Myers, Brenda J. Andrews, Charles Boone, Jason Moffat

Nat Metab. Author manuscript; available in PMC 2020 Dec 1.

Published in final edited form as: Nat Metab. 2020 Jun; 2(6): 499–513. Published online 2020 Jun 1. doi: 10.1038/s42255-020-0211-z

PMCID:: PMC7566881

Abstract Article PDF–4.8M

Select item 746721818.

Low transferrin saturation (TSAT) and high ferritin levels are significant predictors for cerebrovascular and cardiovascular disease and death in maintenance hemodialysis patients

Takahiro Kuragano, Nobuhiko Joki, Hiroki Hase, Kenichiro Kitamura, Toshiaki Murata, Shouichi Fujimoto, Atushi Fukatsu, Toru Inoue, Yukihiro Itakura, Takeshi Nakanishi

PLoS One. 2020; 15(9): e0236277. Published online 2020 Sep 2. doi: 10.1371/journal.pone.0236277

PMCID:: PMC7467218

Abstract Article PDF–1.5M

Select item 741133619.

Antibodies specific to ferritin light chain polypeptide are frequently detected in patients with immune-related pancytopenia

Shanfeng Hao, Yang Zhang, Luogang Hua, Ning Xie, Na Xiao, Huaquan Wang, Rong Fu, Zonghong Shao

Mol Med Rep. 2020 Sep; 22(3): 2012–2020. Published online 2020 Jun 26. doi: 10.3892/mmr.2020.11280

PMCID:: PMC7411336

Abstract Article PDF–1.1M

Select item 736785420.

Hepcidin and ferritin levels in restless legs syndrome: a case–control study

Sofiene Chenini, Constance Delaby, Anna-Laura Rassu, Lucie Barateau, Jérôme Vialaret, Christophe Hirtz, Anne Marie Dupuy, Sylvain Lehmann, Isabelle Jaussent, Yves Dauvilliers

Sci Rep. 2020; 10: 11914. Published online 2020 Jul 17. doi: 10.1038/s41598-020-68851-0

PMCID:: PMC7367854

Abstract Article PDF–988K

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