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Items: 1 to 20 of 44

1.
De Novo Variants in MRTFB have gain of function activity in Drosophila and are associated with a novel neurodevelopmental phenotype with dysmorphic features
Jonathan C. Andrews, Jung-Wan Mok, Oguz Kanca, Sharayu Jangam, Cynthia Tifft, Ellen F. Macnamara, Bianca E. Russell, Lee-kai Wang, Undiagnosed Diseases Network, Stanley F. Nelson, Hugo J. Bellen, Shinya Yamamoto, May Christine V. Malicdan, Michael F. Wangler
Genet Med. Author manuscript; available in PMC 2024 Nov 4.
Published in final edited form as: Genet Med. 2023 Jun; 25(6): 100833. Published online 2023 Mar 31. doi: 10.1016/j.gim.2023.100833
PMCID:
PMC11533975
AbstractArticlePDF–3.3M
2.
Genomic Diversity Illuminates the Environmental Adaptation of Drosophila suzukii
Siyuan Feng, Samuel P DeGrey, Christelle Guédot, Sean D Schoville, John E Pool
Genome Biol Evol. 2024 Sep; 16(9): evae195. Published online 2024 Sep 5. doi: 10.1093/gbe/evae195
PMCID:
PMC11421661
AbstractArticlePDF–1.3M
3.
Astrocytes control quiescent NSC reactivation via GPCR signaling–mediated F-actin remodeling
Kun-Yang Lin, Mahekta R. Gujar, Jiaen Lin, Wei Yung Ding, Jiawen Huang, Yang Gao, Ye Sing Tan, Xiang Teng, Low Siok Lan Christine, Pakorn Kanchanawong, Yusuke Toyama, Hongyan Wang
Sci Adv. 2024 Jul 26; 10(30): eadl4694. Published online 2024 Jul 24. doi: 10.1126/sciadv.adl4694
PMCID:
PMC11268418
AbstractArticlePDF–19M
4.
Activation of an actin signaling pathway in pre-malignant mammary epithelial cells by P-cadherin is essential for transformation
Lídia Faria, Sara Canato, Tito T. Jesus, Margarida Gonçalves, Patrícia S. Guerreiro, Carla S. Lopes, Isabel Meireles, Eurico Morais-de-Sá, Joana Paredes, Florence Janody
Dis Model Mech. 2023 Feb 1; 16(2): dmm049652. Published online 2023 Feb 21. doi: 10.1242/dmm.049652
PMCID:
PMC9983776
AbstractArticle
5.
Transcriptome analysis of FOXO-dependent hypoxia gene expression identifies Hipk as a regulator of low oxygen tolerance in Drosophila
Kate Ding, Elizabeth C Barretto, Michael Johnston, Byoungchun Lee, Marco Gallo, Savraj S Grewal
G3 (Bethesda) 2022 Dec; 12(12): jkac263. Published online 2022 Oct 6. doi: 10.1093/g3journal/jkac263
PMCID:
PMC9713431
AbstractArticlePDF–1.0M
6.
An expanded toolkit for Drosophila gene tagging using synthesized homology donor constructs for CRISPR-mediated homologous recombination
Oguz Kanca, Jonathan Zirin, Yanhui Hu, Burak Tepe, Debdeep Dutta, Wen-Wen Lin, Liwen Ma, Ming Ge, Zhongyuan Zuo, Lu-Ping Liu, Robert W Levis, Norbert Perrimon, Hugo J Bellen
eLife. 2022; 11: e76077. Published online 2022 Jun 20. doi: 10.7554/eLife.76077
PMCID:
PMC9239680
AbstractArticlePDF–1.2M
7.
Mutations disrupting neuritogenesis genes confer risk for cerebral palsy
Sheng Chih Jin, Sara A. Lewis, Somayeh Bakhtiari, Xue Zeng, Michael C. Sierant, Sheetal Shetty, Sandra M. Nordlie, Aureliane Elie, Mark A. Corbett, Bethany Y. Norton, Clare L. van Eyk, Shozeb Haider, Brandon S. Guida, Helen Magee, James Liu, Stephen Pastore, John B. Vincent, Janice Brunstrom-Hernandez, Antigone Papavasileiou, Michael C. Fahey, Jesia G. Berry, Kelly Harper, Chongchen Zhou, Junhui Zhang, Boyang Li, Jennifer Heim, Dani L. Webber, Mahalia S. B. Frank, Lei Xia, Yiran Xu, Dengna Zhu, Bohao Zhang, Amar H. Sheth, James R. Knight, Christopher Castaldi, Irina R. Tikhonova, Francesc López-Giráldez, Boris Keren, Sandra Whalen, Julien Buratti, Diane Doummar, Megan Cho, Kyle Retterer, Francisca Millan, Yangong Wang, Jeff L. Waugh, Lance Rodan, Julie S. Cohen, Ali Fatemi, Angela E. Lin, John P. Phillips, Timothy Feyma, Suzanna C. MacLennan, Spencer Vaughan, Kylie E. Crompton, Susan M. Reid, Dinah S. Reddihough, Qing Shang, Chao Gao, Iona Novak, Nadia Badawi, Yana A. Wilson, Sarah J. McIntyre, Shrikant M. Mane, Xiaoyang Wang, David J. Amor, Daniela C. Zarnescu, Qiongshi Lu, Qinghe Xing, Changlian Zhu, Kaya Bilguvar, Sergio Padilla-Lopez, Richard P. Lifton, Jozef Gecz, Alastair H. MacLennan, Michael C. Kruer
Nat Genet. Author manuscript; available in PMC 2022 May 29.
Published in final edited form as: Nat Genet. 2020 Oct; 52(10): 1046–1056. Published online 2020 Sep 28. doi: 10.1038/s41588-020-0695-1
Correction in:
Nat Genet. 2021 Jan 11
PMCID:
PMC9148538
AbstractArticlePDF–3.8M
8.
Identification of genes contributing to a long circadian period in Drosophila melanogaster
Shailesh Kumar, Ilker Tunc, Terry R. Tansey, Mehdi Pirooznia, Susan T. Harbison
J Biol Rhythms. Author manuscript; available in PMC 2021 Aug 27.
Published in final edited form as: J Biol Rhythms. 2021 Jun; 36(3): 239–253. Published online 2020 Dec 4. doi: 10.1177/0748730420975946
PMCID:
PMC8390771
AbstractArticlePDF–2.4M
9.
Promoter-Proximal Chromatin Domain Insulator Protein BEAF Mediates Local and Long-Range Communication with a Transcription Factor and Directly Activates a Housekeeping Promoter in Drosophila
Yuankai Dong, S. V. Satya Prakash Avva, Mukesh Maharjan, Janice Jacobi, Craig M. Hart
Genetics. 2020 May; 215(1): 89–101. Published online 2020 Mar 16. doi: 10.1534/genetics.120.303144
PMCID:
PMC7198264
AbstractArticlePDF–1.3M
10.
Nuclear Actin Is Required for Transcription during Drosophila Oogenesis
Maria Sokolova, Henna M. Moore, Bina Prajapati, Joseph Dopie, Leena Meriläinen, Mikko Honkanen, Rita Cerejeira Matos, Minna Poukkula, Ville Hietakangas, Maria K. Vartiainen
iScience. 2018 Nov 30; 9: 63–70. Published online 2018 Oct 15. doi: 10.1016/j.isci.2018.10.010
PMCID:
PMC6214840
AbstractArticlePDF–2.7M
11.
The impact of genome variation and diet on the metabolic phenotype and microbiome composition of Drosophila melanogaster
Lisa Jehrke, Fiona A. Stewart, Andrea Droste, Mathias Beller
Sci Rep. 2018; 8: 6215. Published online 2018 Apr 18. doi: 10.1038/s41598-018-24542-5
PMCID:
PMC5906449
AbstractArticlePDF–4.5M
12.
Landscape and evolution of tissue-specific alternative polyadenylation across Drosophila species
Piero Sanfilippo, Jiayu Wen, Eric C. Lai
Genome Biol. 2017; 18: 229. Published online 2017 Nov 30. doi: 10.1186/s13059-017-1358-0
PMCID:
PMC5707805
AbstractArticlePDF–3.2M
13.
Transcription elongation rate has a tissue-specific impact on alternative cleavage and polyadenylation in Drosophila melanogaster
Xiaochuan Liu, Jaime Freitas, Dinghai Zheng, Marta S. Oliveira, Mainul Hoque, Torcato Martins, Telmo Henriques, Bin Tian, Alexandra Moreira
RNA. 2017 Dec; 23(12): 1807–1816. doi: 10.1261/rna.062661.117
PMCID:
PMC5689002
AbstractArticlePDF–4.0M
14.
Transcriptional responses to hyperplastic MRL signalling in Drosophila
Vincent Jonchère, Nada Alqadri, John Herbert, Lauren Dodgson, David Mason, Giovanni Messina, Francesco Falciani, Daimark Bennett
Open Biol. 2017 Feb; 7(2): 160306. Published online 2017 Feb 1. doi: 10.1098/rsob.160306
PMCID:
PMC5356444
AbstractArticlePDF–1.7M
15.
The genetic basis of natural variation in mushroom body size in Drosophila melanogaster
Liesbeth Zwarts, Lies Vanden Broeck, Elisa Cappuyns, Julien F. Ayroles, Michael M. Magwire, Veerle Vulsteke, Jason Clements, Trudy F. C. Mackay, Patrick Callaerts
Nat Commun. 2015; 6: 10115. Published online 2015 Dec 11. doi: 10.1038/ncomms10115
PMCID:
PMC4682101
AbstractArticlePDF–2.0M
16.
Putative synaptic genes defined from a Drosophila whole body developmental transcriptome by a machine learning approach
Flavio Pazos Obregón, Cecilia Papalardo, Sebastián Castro, Gustavo Guerberoff, Rafael Cantera
BMC Genomics. 2015; 16(1): 694. Published online 2015 Sep 15. doi: 10.1186/s12864-015-1888-3
PMCID:
PMC4570697
AbstractArticlePDF–2.0M
17.
Genome-wide Identification of Zero Nucleotide Recursive Splicing in Drosophila
Michael O. Duff, Sara Olson, Xintao Wei, Sandra C. Garrett, Ahmad Osman, Mohan Bolisetty, Alex Plocik, Susan Celniker, Brenton R. Graveley
Nature. Author manuscript; available in PMC 2015 Nov 21.
Published in final edited form as: Nature. 2015 May 21; 521(7552): 376–379. Published online 2015 May 13. doi: 10.1038/nature14475
PMCID:
PMC4529404
AbstractArticlePDF–2.1M
18.
Gene Model Annotations for Drosophila melanogaster: The Rule-Benders
Madeline A. Crosby, L. Sian Gramates, Gilberto dos Santos, Beverley B. Matthews, Susan E. St. Pierre, Pinglei Zhou, Andrew J. Schroeder, Kathleen Falls, David B. Emmert, Susan M. Russo, William M. Gelbart, the FlyBase Consortium
G3 (Bethesda) 2015 Aug; 5(8): 1737–1749. Published online 2015 Jun 24. doi: 10.1534/g3.115.018937
PMCID:
PMC4528330
AbstractArticlePDF–2.2M
19.
Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data
Beverley B. Matthews, Gilberto dos Santos, Madeline A. Crosby, David B. Emmert, Susan E. St. Pierre, L. Sian Gramates, Pinglei Zhou, Andrew J. Schroeder, Kathleen Falls, Victor Strelets, Susan M. Russo, William M. Gelbart, the FlyBase Consortium
G3 (Bethesda) 2015 Aug; 5(8): 1721–1736. Published online 2015 Jun 24. doi: 10.1534/g3.115.018929
PMCID:
PMC4528329
AbstractArticlePDF–4.9M
20.
Genome-Wide Mapping of Collier In Vivo Binding Sites Highlights Its Hierarchical Position in Different Transcription Regulatory Networks
Mathilde de Taffin, Yannick Carrier, Laurence Dubois, Laetitia Bataillé, Anaïs Painset, Stéphanie Le Gras, Bernard Jost, Michèle Crozatier, Alain Vincent
PLoS One. 2015; 10(7): e0133387. Published online 2015 Jul 23. doi: 10.1371/journal.pone.0133387
PMCID:
PMC4512700
AbstractArticlePDF–3.6M

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