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Select item 113919671.

Anti-aging and immunomodulatory role of caffeine in Drosophila larvae

Firzan Nainu, Sartini Sartini, Muhammad A. Bahar, Asbah Asbah, Reski A. Rosa, Mukarram Mudjahid, Muhammad F. As’ad, Nadila P. Latada

Narra J. 2024 Aug; 4(2): e818. Published online 2024 Jun 28. doi: 10.52225/narra.v4i2.818

PMCID:: PMC11391967

Abstract Article PDF–368K

Select item 113235522.

The endosymbiont Spiroplasma poulsonii increases Drosophila melanogaster resistance to pathogens by enhancing iron sequestration and melanization

Alexandra Hrdina, Marina Serra Canales, Aranzazu Arias-Rojas, Dagmar Frahm, Igor Iatsenko

mBio. 2024 Aug; 15(8): e00936-24. Published online 2024 Jun 28. doi: 10.1128/mbio.00936-24

PMCID:: PMC11323552

Abstract Article PDF–2.2M

Select item 108162823.

The Lifespan of D. melanogaster Depends on the Function of the Gagr Gene, a Domesticated gag Gene of Drosophila LTR Retrotransposons

Yevgenia Balakireva, Maria Nikitina, Pavel Makhnovskii, Inna Kukushkina, Ilya Kuzmin, Alexander Kim, Lidia Nefedova

Insects. 2024 Jan; 15(1): 68. Published online 2024 Jan 17. doi: 10.3390/insects15010068

PMCID:: PMC10816282

Abstract Article PDF–4.1M

Select item 107326904.

A Drosophila melanogaster model shows that fast growing Metarhizium species are the deadliest despite eliciting a strong immune response

Jonathan B. Wang, Hsiao-Ling Lu, Huiyu Sheng, Raymond J St. Leger

Virulence. 2023; 14(1): 2275493. Published online 2023 Nov 8. doi: 10.1080/21505594.2023.2275493

PMCID:: PMC10732690

Abstract Article PDF–4.7M

Select item 107325365.

An evolutionarily conserved serine protease network mediates melanization and Toll activation in Drosophila

Tisheng Shan, Yang Wang, Krishna Bhattarai, Haobo Jiang

Sci Adv. 2023 Dec 22; 9(51): eadk2756. Published online 2023 Dec 20. doi: 10.1126/sciadv.adk2756

PMCID:: PMC10732536

Abstract Article PDF–1.3M

Select item 102703516.

Damage sensing mediated by serine proteases Hayan and Persephone for Toll pathway activation in apoptosis-deficient flies

Shotaro Nakano, Soshiro Kashio, Kei Nishimura, Asuka Takeishi, Hina Kosakamoto, Fumiaki Obata, Erina Kuranaga, Takahiro Chihara, Yoshio Yamauchi, Toshiaki Isobe, Masayuki Miura

PLoS Genet. 2023 Jun; 19(6): e1010761. Published online 2023 Jun 15. doi: 10.1371/journal.pgen.1010761

PMCID:: PMC10270351

Abstract Article PDF–2.8M

Select item 89446667.

Injury-induced inflammatory signaling and hematopoiesis in Drosophila

Cory J. Evans, Ting Liu, Juliet R. Girard, Utpal Banerjee

Proc Natl Acad Sci U S A. 2022 Mar 22; 119(12): e2119109119. Published online 2022 Mar 14. doi: 10.1073/pnas.2119109119

PMCID:: PMC8944666

Abstract Article PDF–2.5M

Select item 87743908.

Wnt Signaling Rescues Amyloid Beta-Induced Gut Stem Cell Loss

Prameet Kaur, Ellora Hui Zhen Chua, Wen Kin Lim, Jiarui Liu, Nathan Harmston, Nicholas S. Tolwinski

Cells. 2022 Jan; 11(2): 281. Published online 2022 Jan 14. doi: 10.3390/cells11020281

PMCID:: PMC8774390

Abstract Article PDF–35M

Select item 87105509.

cGMP signaling pathway that modulates NF-κB activation in innate immune responses

Hirotaka Kanoh, Shinzo Iwashita, Takayuki Kuraishi, Akira Goto, Naoyuki Fuse, Haruna Ueno, Mariko Nimura, Tomohito Oyama, Chang Tang, Ryo Watanabe, Aki Hori, Yoshiki Momiuchi, Hiroki Ishikawa, Hiroaki Suzuki, Kumiko Nabe, Takeshi Takagaki, Masataka Fukuzaki, Li-Li Tong, Sinya Yamada, Yoshiteru Oshima, Toshiro Aigaki, Julian A.T. Dow, Shireen-Anne Davies, Shoichiro Kurata

iScience. 2021 Dec 17; 24(12): 103473. Published online 2021 Nov 18. doi: 10.1016/j.isci.2021.103473

PMCID:: PMC8710550

Abstract Article PDF–2.6M

Select item 847793810.

Deciphering of Candida parapsilosis induced immune response in Drosophila melanogaster

Katalin Csonka, Zsolt Tasi, Viktor Vedelek, Csaba Vágvölgyi, Rita Sinka, Attila Gácser

Virulence. 2021; 12(1): 2571–2582. Published online 2021 Sep 27. doi: 10.1080/21505594.2021.1980989

PMCID:: PMC8477938

Abstract Article PDF–1.1M

Select item 761070311.

A SuperFamily-Wide Activity Atlas of Serine Hydrolases in Drosophila Melanogaster

Kundan Kumar, Amol Mhetre, Girish S. Ratnaparkhi, Siddhesh S. Kamat

Biochemistry. Author manuscript; available in PMC 2021 Oct 27.

Published in final edited form as: Biochemistry. 2021 Apr 27; 60(16): 1312–1324. Published online 2021 Apr 7. doi: 10.1021/acs.biochem.1c00171

PMCID:: PMC7610703

Abstract Article PDF–1.7M

Select item 745831212.

Anthrax toxin component, Protective Antigen, protects insects from bacterial infections

Saleem Alameh, Gloria Bartolo, Summer O’Brien, Elizabeth A. Henderson, Leandra O. Gonzalez, Stella Hartmann, Christopher P. Klimko, Jennifer L. Shoe, Christopher K. Cote, Laurence K. Grill, Anastasia Levitin, Mikhail Martchenko Shilman

PLoS Pathog. 2020 Aug; 16(8): e1008836. Published online 2020 Aug 31. doi: 10.1371/journal.ppat.1008836