PMC Links for GEO Profiles (Select 10061904) - PMC

Nils H. Wildner, Andreas Walker, Franziska Brauneck, Vanessa Ditt, Sven Peine, Samuel Huber, Friedrich Haag, Claudia Beisel, Joerg Timm, Julian Schulze zur Wiesch

Front Immunol. 2022; 13: 886646. Published online 2022 Jun 6. doi: 10.3389/fimmu.2022.886646

PMCID:: PMC9207347

Abstract Article PDF–5.2M

Select item 88031064.

CD4+ T cells in classical Hodgkin lymphoma express exhaustion associated transcription factors TOX and TOX2: Characterizing CD4+ T cells in Hodgkin lymphoma

Johanna Veldman, Jessica Rodrigues Plaça, Lauren Chong, Miente Martijn Terpstra, Mirjam Mastik, Léon C. van Kempen, Klaas Kok, Tomohiro Aoki, Christian Steidl, Anke van den Berg, Lydia Visser, Arjan Diepstra

Oncoimmunology. 2022; 11(1): 2033433. Published online 2022 Jan 27. doi: 10.1080/2162402X.2022.2033433

PMCID:: PMC8803106

Abstract Article PDF–2.1M

Select item 81650305.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 80915126.

Normal and cancer fibroblasts differentially regulate TWIST1, TOX and cytokine gene expression in cutaneous T-cell lymphoma

Syed Jafar Mehdi, Andrea Moerman-Herzog, Henry K. Wong

BMC Cancer. 2021; 21: 492. Published online 2021 May 3. doi: 10.1186/s12885-021-08142-7

PMCID:: PMC8091512

Abstract Article PDF–1.5M

Select item 80627167.

TOX Acts as a Tumor Suppressor by Inhibiting mTOR Signaling in Colorectal Cancer

Mengdi Yang, Qianru Huang, Changcan Li, Zhiyuan Jiang, Jing Sun, Zhiyu Wang, Rui Liang, Dan Li, Bin Li, Hui Zhao

Front Immunol. 2021; 12: 647540. Published online 2021 Apr 9. doi: 10.3389/fimmu.2021.647540

PMCID:: PMC8062716

Abstract Article PDF–7.4M

Select item 76989928.

TOX is a critical regulator of tumour-specific T cell differentiation

Andrew C. Scott, Friederike Dündar, Paul Zumbo, Smita S. Chandran, Christopher A. Klebanoff, Mojdeh Shakiba, Prerak Trivedi, Laura Menocal, Heather Appleby, Steven Camara, Dmitriy Zamarin, tyler Walther, Alexandra Snyder, Matthew R. Femia, Elizabeth A. Comen, Hannah Y. Wen, Matthew D. Hellmann, Niroshana Anandasabapathy, Yong Liu, Nasser K. Altorki, Peter Lauer, Olivier Levy, Michael S. Glickman, Jonathan Kaye, Doron Betel, Mary Philip, Andrea Schietinger

Nature. Author manuscript; available in PMC 2020 Nov 28.

Published in final edited form as: Nature. 2019 Jul; 571(7764): 270–274. Published online 2019 Jun 17. doi: 10.1038/s41586-019-1324-y

PMCID:: PMC7698992

Abstract Article PDF–5.5M

Select item 73542819.

Molecular profiling of TOX-deficient neoplastic cells in cutaneous T cell lymphoma

Jingkai Xu, He Huang, Shangshang Wang, Yanzhen Chen, Xueli Yin, Xuejun Zhang, Yaohua Zhang

Arch Dermatol Res. 2020; 312(7): 513–525. Published online 2019 Nov 1. doi: 10.1007/s00403-019-02000-0

PMCID:: PMC7354281

Abstract Article PDF–7.6M

Select item 716998310.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 704813911.

Single-cell transcriptome analysis reveals TOX as a promoting factor for T cell exhaustion and a predictor for anti-PD-1 responses in human cancer

Kyungsoo Kim, Seyeon Park, Seong Yong Park, Gamin Kim, Su Myeong Park, Jae-Won Cho, Da Hee Kim, Young Min Park, Yoon Woo Koh, Hye Ryun Kim, Sang-Jun Ha, Insuk Lee

Genome Med. 2020; 12: 22. Published online 2020 Feb 28. doi: 10.1186/s13073-020-00722-9

PMCID:: PMC7048139

Abstract Article PDF–3.6M

Select item 694291112.

LncRNA MALAT1 Suppression Protects Endothelium against oxLDL-Induced Inflammation via Inhibiting Expression of MiR-181b Target Gene TOX

Liuqing Wang, Yinliang Qi, Yi Wang, Haitao Tang, Zhenzhen Li, Yuan Wang, Songtao Tang, Huaqing Zhu

Oxid Med Cell Longev. 2019; 2019: 8245810. Published online 2019 Dec 14. doi: 10.1155/2019/8245810

PMCID:: PMC6942911

Abstract Article PDF–1.2M

Select item 599379713.

Interactome analyses revealed that the U1 snRNP machinery overlaps extensively with the RNAP II machinery and contains multiple ALS/SMA-causative proteins

Binkai Chi, Jeremy D. O’Connell, Tomohiro Yamazaki, Jaya Gangopadhyay, Steven P. Gygi, Robin Reed

Sci Rep. 2018; 8: 8755. Published online 2018 Jun 8. doi: 10.1038/s41598-018-27136-3

PMCID:: PMC5993797

Abstract Article PDF–2.9M

Select item 568342714.

TOX regulates growth, DNA repair, and genomic instability in T-cell Acute Lymphoblastic Leukemia

Riadh Lobbardi, Jordan Pinder, Barbara Martinez-Pastor, Marina Theodorou, Jessica S. Blackburn, Brian J. Abraham, Yuka Namiki, Marc Mansour, Nouran S. Abdelfattah, Aleksey Molodtsov, Gabriela Alexe, Debra Toiber, Manon de Waard, Esha Jain, Myriam Boukhali, Mattia Lion, Deepak Bhere, Khalid Shah, Alejandro Gutierrez, Kimberly Stegmaier, Lewis B. Silverman, Ruslan I. Sadreyev, John M. Asara, Marjorie A. Oettinger, Wilhelm Haas, A. Thomas Look, Richard A. Young, Raul Mostoslavsky, Graham Dellaire, David M. Langenau

Cancer Discov. Author manuscript; available in PMC 2018 Nov 1.

Published in final edited form as: Cancer Discov. 2017 Nov; 7(11): 1336–1353. Published online 2017 Oct 3. doi: 10.1158/2159-8290.CD-17-0267

PMCID:: PMC5683427

Abstract Article PDF–1.3M

Select item 553161115.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 536112116.

TOX and ADIPOQ Gene Polymorphisms Are Associated with Antipsychotic-Induced Weight Gain in Han Chinese

Shen Li, Chengai Xu, Yuan Tian, Xueshi Wang, Rui Jiang, Miaomiao Zhang, Lili Wang, Guifu Yang, Ying Gao, Chenyu Song, Yukun He, Ying Zhang, Jie Li, Wei-Dong Li

Sci Rep. 2017; 7: 45203. Published online 2017 Mar 22. doi: 10.1038/srep45203

PMCID:: PMC5361121

Abstract Article PDF–576K

Select item 535711817.

CD164 identifies CD4⁺ T cells highly expressing genes associated with malignancy in Sézary syndrome: the Sézary signature genes, FCRL3, Tox and miR-214

Bernice M. Benoit, Neha Jariwala, Geraldine O’Connor, Landon K. Oetjen, Timothy M. Whelan, Adrienne Werth, Andrea B. Troxel, Hélène Sicard, Lisa Zhu, Christopher Miller, Junko Takeshita, Daniel W. McVicar, Brian S. Kim, Alain H. Rook, Maria Wysocka

Arch Dermatol Res. Author manuscript; available in PMC 2018 Jan 1.

Published in final edited form as: Arch Dermatol Res. 2017 Jan; 309(1): 11–19. Published online 2016 Oct 20. doi: 10.1007/s00403-016-1698-8

PMCID:: PMC5357118

Abstract Article PDF–735K

Select item 499242818.

TOX expression and role in CTCL

LY McGirt, CA Degesys, VE Johnson, JA Zic, JP Zwerner, CM Eischen

J Eur Acad Dermatol Venereol. Author manuscript; available in PMC 2017 Sep 1.

Published in final edited form as: J Eur Acad Dermatol Venereol. 2016 Sep; 30(9): 1497–1502. Published online 2016 Jun 26. doi: 10.1111/jdv.13651

PMCID:: PMC4992428

Abstract Article PDF–573K

Select item 465066119.

TOX and CDKN2A/B Gene Polymorphisms Are Associated with Type 2 Diabetes in Han Chinese

Fengjiang Wei, Chunyou Cai, Shuzhi Feng, Jia Lv, Shen Li, Baocheng Chang, Hong Zhang, Wentao Shi, Hongling Han, Chao Ling, Ping Yu, Yongjun Chen, Ning Sun, Jianli Tian, Hongxiao Jiao, Fuhua Yang, Mingshan Li, Yuhua Wang, Lei Zou, Long Su, Jingbo Li, Ran Li, Huina Qiu, Jingmin Shi, Shiying Liu, Mingqin Chang, Jingna Lin, Liming Chen, Wei-Dong Li

Sci Rep. 2015; 5: 11900. Published online 2015 Jul 3. doi: 10.1038/srep11900

PMCID:: PMC4650661

Abstract Article PDF–329K

Select item 429151920.

Genome-wide association study for refractive astigmatism reveals genetic co-determination with spherical equivalent refractive error: the CREAM consortium

Qing Li, Robert Wojciechowski, Claire L. Simpson, Pirro G. Hysi, Virginie J. M. Verhoeven, Mohammad Kamran Ikram, René Höhn, Veronique Vitart, Alex W. Hewitt, Konrad Oexle, Kari-Matti Mäkelä, Stuart MacGregor, Mario Pirastu, Qiao Fan, Ching-Yu Cheng, Beaté St Pourcain, George McMahon, John P. Kemp, Kate Northstone, Jugnoo S. Rahi, Phillippa M. Cumberland, Nicholas G. Martin, Paul G. Sanfilippo, Yi Lu, Ya Xing Wang, Caroline Hayward, Ozren Polašek, Harry Campbell, Goran Bencic, Alan F. Wright, Juho Wedenoja, Tanja Zeller, Arne Schillert, Alireza Mirshahi, Karl Lackner, Shea Ping Yip, Maurice K. H. Yap, Janina S. Ried, Christian Gieger, Federico Murgia, James F. Wilson, Brian Fleck, Seyhan Yazar, Johannes R. Vingerling, Albert Hofman, André Uitterlinden, Fernando Rivadeneira, Najaf Amin, Lennart Karssen, Ben A. Oostra, Xin Zhou, Yik-Ying Teo, E. Shyong Tai, Eranga Vithana, Veluchamy Barathi, Yingfeng Zheng, Rosalynn Grace Siantar, Kumari Neelam, Youchan Shin, Janice Lam, Ekaterina Yonova-Doing, Cristina Venturini, S. Mohsen Hosseini, Hoi-Suen Wong, Terho Lehtimäki, Mika Kähönen, Olli Raitakari, Nicholas J. Timpson, David M. Evans, Chiea-Chuen Khor, Tin Aung, Terri L. Young, Paul Mitchell, Barbara Klein, Cornelia M. van Duijn, Thomas Meitinger, Jost B. Jonas, Paul N. Baird, David A. Mackey, Tien Yin Wong, Seang-Mei Saw, Olavi Pärssinen, Dwight Stambolian, Christopher J. Hammond, Caroline C. W. Klaver, Cathy Williams, Andrew D. Paterson, Joan E. Bailey-Wilson, Jeremy A. Guggenheim, The CREAM Consortium

Hum Genet. 2015; 134(2): 131–146. Published online 2014 Nov 4. doi: 10.1007/s00439-014-1500-y

PMCID:: PMC4291519

Abstract Article PDF–1.3M

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