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Select item 108658661.

Secretory leukocyte protease inhibitor protects against severe urinary tract infection in mice

Anne L. Rosen, Michael A. Lint, Dayne H. Voelker, Nicole M. Gilbert, Christopher P. Tomera, Jesús Santiago-Borges, Meghan A. Wallace, Thomas J. Hannan, Carey-Ann D. Burnham, Scott J. Hultgren, Andrew L. Kau

mBio. 2024 Feb; 15(2): e02554-23. Published online 2024 Jan 25. doi: 10.1128/mbio.02554-23

PMCID:: PMC10865866

Abstract Article PDF–2.8M

Select item 107127362.

Neutrophil elastase selectively kills cancer cells and attenuates tumorigenesis

Chang Cui, Kasturi Chakraborty, Xu Anna Tang, Guolin Zhou, Kelly Q. Schoenfelt, Kristen M. Becker, Alexandria Hoffman, Ya-Fang Chang, Ariane Blank, Catherine A. Reardon, Hilary A. Kenny, Tomas Vaisar, Ernst Lengyel, Geoffrey Greene, Lev Becker

Cell. Author manuscript; available in PMC 2023 Dec 11.

Published in final edited form as: Cell. 2021 Jun 10; 184(12): 3163–3177.e21. Published online 2021 May 7. doi: 10.1016/j.cell.2021.04.016

PMCID:: PMC10712736

Abstract Article PDF–3.3M

Select item 95462833.

Secretory leukocyte protease inhibitor regulates nerve reflex‐mediated skin barrier function in psoriasis

P. Kwiecinska, B. Grygier, A. Morytko, A. Sanecka‐Duin, M. Majchrzak‐Gorecka, M. Kwitniewski, M. Kapinska‐Mrowiecka, G. Porebski, J. Cichy

J Eur Acad Dermatol Venereol. 2022 Aug; 36(8): 1266–1274. Published online 2022 Apr 5. doi: 10.1111/jdv.18065

PMCID:: PMC9546283

Abstract Article PDF–2.3M

Select item 80354054.

SLPI is a critical mediator that controls PTH-induced bone formation

Akito Morimoto, Junichi Kikuta, Keizo Nishikawa, Takao Sudo, Maki Uenaka, Masayuki Furuya, Tetsuo Hasegawa, Kunihiko Hashimoto, Hiroyuki Tsukazaki, Shigeto Seno, Akira Nakamura, Daisuke Okuzaki, Fuminori Sugihara, Akinori Ninomiya, Takeshi Yoshimura, Ryoko Takao-Kawabata, Hideo Matsuda, Masaru Ishii

Nat Commun. 2021; 12: 2136. Published online 2021 Apr 9. doi: 10.1038/s41467-021-22402-x

PMCID:: PMC8035405

Abstract Article PDF–3.3M

Select item 76855105.

Airway Microbiota-Host Interactions Regulate Secretory Leukocyte Protease Inhibitor Levels and Influence Allergic Airway Inflammation

Natalia Jaeger, Ryan T. McDonough, Anne L. Rosen, Ariel Hernandez-Leyva, Naomi G. Wilson, Michael A. Lint, Emilie V. Russler-Germain, Jiani N. Chai, Leonard B. Bacharier, Chyi-Song Hsieh, Andrew L. Kau

Cell Rep. Author manuscript; available in PMC 2020 Nov 24.

Published in final edited form as: Cell Rep. 2020 Nov 3; 33(5): 108331. doi: 10.1016/j.celrep.2020.108331

Correction in:: Cell Rep. 2022 Jan 25; 38(4): 110324.

PMCID:: PMC7685510

Abstract Article PDF–2.5M

Select item 64582936.

SLPI Inhibits ATP-Mediated Maturation of IL-1β in Human Monocytic Leukocytes: A Novel Function of an Old Player

Anna Zakrzewicz, Katrin Richter, Dariusz Zakrzewicz, Kathrin Siebers, Jelena Damm, Alisa Agné, Andreas Hecker, J. Michael McIntosh, Walee Chamulitrat, Gabriela Krasteva-Christ, Ivan Manzini, Ritva Tikkanen, Winfried Padberg, Sabina Janciauskiene, Veronika Grau

Front Immunol. 2019; 10: 664. Published online 2019 Apr 4. doi: 10.3389/fimmu.2019.00664

PMCID:: PMC6458293

Abstract Article PDF–1.5M

Select item 61483057.

MIF-2/D-DT enhances proximal tubular cell regeneration through SLPI- and ATF4-dependent mechanisms

Akinobu Ochi, Dong Chen, Wibke Schulte, Lin Leng, Nickolas Moeckel, Marta Piecychna, Luisa Averdunk, Christian Stoppe, Richard Bucala, Gilbert Moeckel

Am J Physiol Renal Physiol. 2017 Sep 1; 313(3): F767–F780. Published online 2017 May 24. doi: 10.1152/ajprenal.00683.2016

PMCID:: PMC6148305

Abstract Article

Select item 55294948.

Secretory leukocyte protease inhibitor regulates human periodontal ligament cell production of pro-inflammatory cytokines

Daniel Svensson, Alexandra Aidoukovitch, Emma Anders, Daniel Jönsson, Daniel Nebel, Bengt-Olof Nilsson

Inflamm Res. 2017; 66(9): 823–831. Published online 2017 Jun 8. doi: 10.1007/s00011-017-1062-2

PMCID:: PMC5529494

Abstract Article PDF–873K

Select item 49702139.

Decreased expression levels of Ifi genes is associated to the increased resistance to spontaneous arthritis disease in mice deficiency of IL-1RA

Xiaoyun Liu, Yan Jiao, Yanhong Cao, Nan Deng, Yonghui Ma, Karen A. Hasty, Andrew Kang, Hong Chen, John M. Stuart, Weikuan Gu

BMC Immunol. 2016; 17: 25. Published online 2016 Aug 2. doi: 10.1186/s12865-016-0163-y

PMCID:: PMC4970213

Abstract Article PDF–2.5M

Select item 488444910.

Secretory leukocyte protease inhibitor gene deletion alters bleomycin-induced lung injury, but not development of pulmonary fibrosis

Anthony N Habgood, Amanda L Tatler, Joanne Porte, Sharon M Wahl, Geoffrey J Laurent, Alison E John, Simon R Johnson, Gisli Jenkins

Lab Invest. Author manuscript; available in PMC 2016 Sep 22.

Published in final edited form as: Lab Invest. 2016 Jun; 96(6): 623–631. Published online 2016 Mar 14. doi: 10.1038/labinvest.2016.40

PMCID:: PMC4884449

Abstract Article PDF–1.8M

Select item 475454211.

Syndecan 4 Mediates Nrf2-dependent Expansion of Bronchiolar Progenitors That Protect Against Lung Inflammation

Arif Santoso, Toshiaki Kikuchi, Naoki Tode, Taizou Hirano, Riyo Komatsu, Triya Damayanti, Hozumi Motohashi, Masayuki Yamamoto, Tetsuhito Kojima, Toshimitsu Uede, Toshihiro Nukiwa, Masakazu Ichinose

Mol Ther. 2016 Feb; 24(1): 41–52. Prepublished online 2015 Aug 26. Published online 2015 Sep 22. doi: 10.1038/mt.2015.153

PMCID:: PMC4754542

Abstract Article PDF–2.4M

Select item 467427312.

A keratin scaffold regulates epidermal barrier formation, mitochondrial lipid composition, and activity

Vinod Kumar, Jamal-Eddine Bouameur, Janina Bär, Robert H. Rice, Hue-Tran Hornig-Do, Dennis R. Roop, Nicole Schwarz, Susanne Brodesser, Sören Thiering, Rudolf E. Leube, Rudolf J. Wiesner, Preethi Vijayaraj, Christina B. Brazel, Sandra Heller, Hans Binder, Henry Löffler-Wirth, Peter Seibel, Thomas M. Magin

J Cell Biol. 2015 Dec 7; 211(5): 1057–1075. doi: 10.1083/jcb.201404147

Correction in:: J Cell Biol. 2016 Mar 28; 212(7): 877.

PMCID:: PMC4674273

Abstract Article PDF–4.4M

Select item 456375413.

High IFN-γ and low SLPI mark severe asthma in mice and humans

Mahesh Raundhal, Christina Morse, Anupriya Khare, Timothy B. Oriss, Jadranka Milosevic, John Trudeau, Rachael Huff, Joseph Pilewski, Fernando Holguin, Jay Kolls, Sally Wenzel, Prabir Ray, Anuradha Ray

J Clin Invest. 2015 Aug 3; 125(8): 3037–3050. Published online 2015 Jun 29. doi: 10.1172/JCI80911

PMCID:: PMC4563754

Abstract Article PDF–3.4M

Select item 446716814.

The inhibitory effect of secretory leukocyte protease inhibitor (SLPI) on formation of neutrophil extracellular traps

Katarzyna Zabieglo, Pawel Majewski, Monika Majchrzak-Gorecka, Agnieszka Wlodarczyk, Beata Grygier, Aneta Zegar, Monika Kapinska-Mrowiecka, Antonina Naskalska, Krzysztof Pyrc, Adam Dubin, Sharon M. Wahl, Joanna Cichy

J Leukoc Biol. 2015 Jul; 98(1): 99–106. Published online 2015 Apr 27. doi: 10.1189/jlb.4AB1114-543R

PMCID:: PMC4467168

Abstract Article

Select item 424064515.

MyD88 Deficiency Alters Expression of Antimicrobial Factors in Mouse Salivary Glands

Takeshi Into, Toshiya Takigawa, Shumpei Niida, Ken-ichiro Shibata

PLoS One. 2014; 9(11): e113333. Published online 2014 Nov 21. doi: 10.1371/journal.pone.0113333

PMCID:: PMC4240645

Abstract Article PDF–1.6M

Select item 419755616.

Aberrant host defense against Leishmania major in the absence of SLPI

Nancy McCartney-Francis, Wenwen Jin, Yasmine Belkaid, George McGrady, Sharon M. Wahl

J Leukoc Biol. 2014 Nov; 96(5): 917–929. doi: 10.1189/jlb.4A0612-295RR

PMCID:: PMC4197556

Abstract Article

Select item 412866017.

Increased Secretory Leukocyte Protease Inhibitor (SLPI) Production by Highly Metastatic Mouse Breast Cancer Cells

Kevin T. Sayers, Alan D. Brooks, Thomas J. Sayers, Oleg Chertov

PLoS One. 2014; 9(8): e104223. Published online 2014 Aug 11. doi: 10.1371/journal.pone.0104223

PMCID:: PMC4128660

Abstract Article PDF–1.0M

Select item 362294218.

β2-adrenergic receptor activation prevents rodent dopaminergic neurotoxicity by inhibiting microglia via a novel signaling pathway

Li Qian, Hung-ming Wu, Shih-Heng Chen, Dan Zhang, Syed F. Ali, Lynda Peterson, Belinda Wilson, Ru-Band Lu, Jau-Shyong Hong, Patrick M Flood

J Immunol. Author manuscript; available in PMC 2013 Apr 11.

Published in final edited form as: J Immunol. 2011 Apr 1; 186(7): 4443–4454. Published online 2011 Feb 18. doi: 10.4049/jimmunol.1002449

PMCID:: PMC3622942

Abstract Article PDF–3.1M

Select item 357241019.

A conditional knockout resource for the genome–wide study of mouse gene function

William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley

Nature. Author manuscript; available in PMC 2013 Feb 14.

Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163