PMC Links for GEO Profiles (Select 100059645) - PMC

Hao Sun, Ho-Sup Lee, Sarah Hyun-Ji Kim, Mikhael Fernandes de Lima, Alexandre R. Gingras, Qinyi Du, Wilma McLaughlin, Jailail Ablack, Miguel A. Lopez-Ramirez, Frederic Lagarrigue, Zhichao Fan, John T. Chang, Derek VanDyke, Jamie B. Spangler, Mark H. Ginsberg

Cell Rep. Author manuscript; available in PMC 2023 Oct 10.

Published in final edited form as: Cell Rep. 2023 Aug 29; 42(8): 112996. Published online 2023 Aug 21. doi: 10.1016/j.celrep.2023.112996

PMCID:: PMC10564087

Abstract Article PDF–2.7M

Select item 103992224.

The critical role of Rap1-GAPs Rasa3 and Sipa1 in T cells for pulmonary transit and egress from the lymph nodes

Shunsuke Horitani, Yoshihiro Ueda, Yuji Kamioka, Naoyuki Kondo, Yoshiki Ikeda, Makoto Naganuma, Tatsuo Kinashi

Front Immunol. 2023; 14: 1234747. Published online 2023 Jul 20. doi: 10.3389/fimmu.2023.1234747

PMCID:: PMC10399222

Abstract Article PDF–8.9M

Select item 99239315.

Disruption of protein geranylgeranylation in the cerebellum causes cerebellar hypoplasia and ataxia via blocking granule cell progenitor proliferation

Qi Cheng, Jing Wu, Yingqian Xia, Qing Cheng, Yinjuan Zhao, Peixiang Zhu, Wangling Zhang, Shihu Zhang, Lei Zhang, Yushan Yuan, Chaojun Li, Guiquan Chen, Bin Xue

Mol Brain. 2023; 16: 24. Published online 2023 Feb 13. doi: 10.1186/s13041-023-01010-4

PMCID:: PMC9923931

Abstract Article PDF–8.3M

Select item 96444096.

Direct Binding of Rap1 to Talin1 and to MRL Proteins Promotes Integrin Activation in CD4⁺ T Cells

Frederic Lagarrigue, Boyang Tan, Qinyi Du, Zhichao Fan, Miguel A. Lopez-Ramirez, Alexandre R. Gingras, Hsin Wang, Weiwei Qi, Hao Sun

J Immunol. Author manuscript; available in PMC 2023 Mar 15.

Published in final edited form as: J Immunol. 2022 Mar 15; 208(6): 1378–1388. Published online 2022 Feb 23. doi: 10.4049/jimmunol.2100843

PMCID:: PMC9644409

Abstract Article PDF–1.9M

Select item 94468007.

Hepatocyte Rap1a contributes to obesity- and statin-associated hyperglycemia

Yating Wang, Stefano Spolitu, John A. Zadroga, Amesh K. Sarecha, Lale Ozcan

Cell Rep. Author manuscript; available in PMC 2022 Sep 6.

Published in final edited form as: Cell Rep. 2022 Aug 23; 40(8): 111259. doi: 10.1016/j.celrep.2022.111259

PMCID:: PMC9446800

Abstract Article PDF–1.2M

Select item 93559588.

MiR-1224-5p modulates osteogenesis by coordinating osteoblast/osteoclast differentiation via the Rap1 signaling target ADCY2

Liangcong Hu, Xudong Xie, Hang Xue, Tiantian Wang, Adriana C. Panayi, Ze Lin, Yuan Xiong, Faqi Cao, Chengcheng Yan, Lang Chen, Peng Cheng, Kangkang Zha, Yun Sun, Guodong Liu, Chenyan Yu, Yiqiang Hu, Ranyang Tao, Wu Zhou, Bobin Mi, Guohui Liu

Exp Mol Med. 2022 Jul; 54(7): 961–972. Published online 2022 Jul 13. doi: 10.1038/s12276-022-00799-9

PMCID:: PMC9355958

Abstract Article PDF–6.0M

Select item 91011269.

Rap1a Activity Elevated the Impact of Endogenous AGEs in Diabetic Collagen to Stimulate Increased Myofibroblast Transition and Oxidative Stress

Stephanie D. Burr, Christopher C. Dorroh, James A. Stewart, Jr.

Int J Mol Sci. 2022 May; 23(9): 4480. Published online 2022 Apr 19. doi: 10.3390/ijms23094480

PMCID:: PMC9101126

Abstract Article PDF–2.0M

Select item 906265910.

Interactome and Ubiquitinome Analyses Identify Functional Targets of Herpes Simplex Virus 1 Infected Cell Protein 0

Fujun Hou, Zeyu Sun, Yue Deng, Siyu Chen, Xiyuan Yang, Feiyang Ji, Menghao Zhou, Keyi Ren, Dongli Pan

Front Microbiol. 2022; 13: 856471. Published online 2022 Apr 18. doi: 10.3389/fmicb.2022.856471

PMCID:: PMC9062659

Abstract Article PDF–3.5M

Select item 889743611.

Rap1 prevents colitogenic Th17 cell expansion and facilitates Treg cell differentiation and distal TCR signaling

Sayaka Ishihara, Tsuyoshi Sato, Noriyuki Fujikado, Haruka Miyazaki, Takayuki Yoshimoto, Hiromitsu Yamamoto, Shinji Fukuda, Koko Katagiri

Commun Biol. 2022; 5: 206. Published online 2022 Mar 4. doi: 10.1038/s42003-022-03129-x

PMCID:: PMC8897436

Abstract Article PDF–3.0M

Select item 835388412.

SLX4IP promotes RAP1 SUMOylation by PIAS1 to coordinate telomere maintenance through NF-κB and Notch signaling

Nathaniel J. Robinson, Masaru Miyagi, Jessica A. Scarborough, Jacob G. Scott, Derek J. Taylor, William P. Schiemann

Sci Signal. Author manuscript; available in PMC 2021 Dec 29.

Published in final edited form as: Sci Signal. 2021 Jun 29; 14(689): eabe9613. Published online 2021 Jun 29. doi: 10.1126/scisignal.abe9613

PMCID:: PMC8353884

Abstract Article PDF–2.9M

Select item 826236413.

Rap1 in the VMH regulates glucose homeostasis

Kentaro Kaneko, Hsiao-Yun Lin, Yukiko Fu, Pradip K. Saha, Ana B. De la Puente-Gomez, Yong Xu, Kousaku Ohinata, Peter Chen, Alexei Morozov, Makoto Fukuda

JCI Insight. 2021 Jun 8; 6(11): e142545. Published online 2021 Jun 8. doi: 10.1172/jci.insight.142545

PMCID:: PMC8262364

Abstract Article PDF–1.4M

Select item 820392714.

Rap1 Is Essential for B-Cell Locomotion, Germinal Center Formation and Normal B-1a Cell Population

Sayaka Ishihara, Tsuyoshi Sato, Risa Sugioka, Ryota Miwa, Haruka Saito, Ryota Sato, Hidehiro Fukuyama, Akihiko Nakajima, Satoshi Sawai, Ai Kotani, Koko Katagiri

Front Immunol. 2021; 12: 624419. Published online 2021 Jun 1. doi: 10.3389/fimmu.2021.624419

PMCID:: PMC8203927

Abstract Article PDF–3.6M

Select item 799211215.

Large Extracellular Vesicle-Associated Rap1 Accumulates in Atherosclerotic Plaques, Correlates With Vascular Risks and Is Involved in Atherosclerosis

Liliana Perdomo, Xavier Vidal-Gómez, Raffaella Soleti, Luisa Vergori, Lucie Duluc, Maggy Chwastyniak, Malik Bisserier, Soazig Le Lay, Alexandre Villard, Gilles Simard, Olivier Meilhac, Frank Lezoualc’h, Ilya Khantalin, Reuben Veerapen, Séverine Dubois, Jérôme Boursier, Samir Henni, Frédéric Gagnadoux, Florence Pinet, Ramaroson Andriantsitohaina, M. Carmen Martínez

Circ Res. Author manuscript; available in PMC 2021 Mar 25.

Published in final edited form as: Circ Res. 2020 Aug 28; 127(6): 747–760. Published online 2020 Jun 16. doi: 10.1161/CIRCRESAHA.120.317086

PMCID:: PMC7992112

Abstract Article PDF–2.2M

Select item 759051116.

Distinct integrin activation pathways for effector and regulatory T cell trafficking and function

Hao Sun, Frederic Lagarrigue, Hsin Wang, Zhichao Fan, Miguel Alejandro Lopez-Ramirez, John T. Chang, Mark H. Ginsberg

J Exp Med. 2021 Feb 1; 218(2): e20201524. Published online 2020 Oct 26. doi: 10.1084/jem.20201524

PMCID:: PMC7590511

Abstract Article PDF–4.4M

Select item 705211617.

The Impact of Diabetic Conditions and AGE/RAGE Signaling on Cardiac Fibroblast Migration

Stephanie D. Burr, Mallory B. Harmon, James A. Stewart Jr.

Front Cell Dev Biol. 2020; 8: 112. Published online 2020 Feb 25. doi: 10.3389/fcell.2020.00112

PMCID:: PMC7052116

Abstract Article PDF–3.0M

Select item 691107718.

Rap1 regulates hematopoietic stem cell survival and affects oncogenesis and response to chemotherapy

Ekta Khattar, Kyaw Ze Ya Maung, Chen Li Chew, Arkasubhra Ghosh, Michelle Meng Huang Mok, Pei Lee, Jun Zhang, Wei Hong Jeff Chor, Gökhan Cildir, Chelsia Qiuxia Wang, Nur Khairiah Mohd-Ismail, Desmond Wai Loon Chin, Soo Chin Lee, Henry Yang, Yong-Jae Shin, Do-Hyun Nam, Liming Chen, Alan Prem Kumar, Lih Wen Deng, Masahito Ikawa, Jayantha Gunaratne, Motomi Osato, Vinay Tergaonkar

Nat Commun. 2019; 10: 5349. Published online 2019 Dec 13. doi: 10.1038/s41467-019-13082-9

PMCID:: PMC6911077

Abstract Article PDF–2.5M

Select item 671535919.

Gut-derived GIP activates central Rap1 to impair neural leptin sensitivity during overnutrition

Kentaro Kaneko, Yukiko Fu, Hsiao-Yun Lin, Elizabeth L. Cordonier, Qianxing Mo, Yong Gao, Ting Yao, Jacqueline Naylor, Victor Howard, Kenji Saito, Pingwen Xu, Siyu S. Chen, Miao-Hsueh Chen, Yong Xu, Kevin W. Williams, Peter Ravn, Makoto Fukuda

J Clin Invest. 2019 Sep 3; 129(9): 3786–3791. Published online 2019 Aug 12. doi: 10.1172/JCI126107

PMCID:: PMC6715359

Abstract Article PDF–3.3M

Select item 667185220.

Enhanced Cortico-Amygdala Efficacy and Suppressed Fear in Absence of Rap1

Bing-Xing Pan, Francois Vautier, Wataru Ito, Vadim Y. Bolshakov, Alexei Morozov

J Neurosci. 2008 Feb 27; 28(9): 2089–2098. doi: 10.1523/JNEUROSCI.5156-07.2008

PMCID:: PMC6671852

Abstract Article PDF–844K

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