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Select item 67457031.

Adaptive endoplasmic reticulum stress signalling via IRE1α-XBP1 preserves self-renewal of haematopoietic and pre-leukaemic stem cells

Lu Liu, Meiling Zhao, Xi Jin, Gina Ney, Kevin B Yang, Fanglue Peng, Jin Cao, Takao Iwawaki, Juan Del Valle, Xi Chen, Qing Li

Nat Cell Biol. Author manuscript; available in PMC 2019 Sep 16.

Published in final edited form as: Nat Cell Biol. 2019 Mar; 21(3): 328–337. Published online 2019 Feb 18. doi: 10.1038/s41556-019-0285-6

PMCID:: PMC6745703

Abstract Article PDF–1.1M

Select item 63380372.

IRE1α Activation in Bone Marrow-Derived Dendritic Cells Modulates Innate Recognition of Melanoma Cells and Favors CD8⁺ T Cell Priming

Bernardita Medel, Cristobal Costoya, Dominique Fernandez, Cristian Pereda, Alvaro Lladser, Daniela Sauma, Rodrigo Pacheco, Takao Iwawaki, Flavio Salazar-Onfray, Fabiola Osorio

Front Immunol. 2018; 9: 3050. Published online 2019 Jan 4. doi: 10.3389/fimmu.2018.03050

PMCID:: PMC6338037

Abstract Article PDF–3.5M

Select item 61861773.

Critical role of endoplasmic reticulum stress in chronic endothelial activation induced visual deficits in tie2-TNF mice

Raji Lenin, Peter G Nagy, Shanta Alli, Vidhya R Rao, Matthias A Clauss, Uday B. Kompella, Rajashekhar Gangaraju

J Cell Biochem. Author manuscript; available in PMC 2019 Nov 1.

Published in final edited form as: J Cell Biochem. 2018 Nov; 119(10): 8460–8471. Published online 2018 Jul 27. doi: 10.1002/jcb.27072

PMCID:: PMC6186177

Abstract Article PDF–1.7M

Select item 61804064.

Featured Article: Deterioration of visual function mediated by senescence-associated endoplasmic reticulum stress in inflammatory tie2-TNF mice

Raji Lenin, Peter G Nagy, Jordy Gentry, Rajashekhar Gangaraju

Exp Biol Med (Maywood) 2018 Aug; 243(12): 976–984. Published online 2018 Aug 16. doi: 10.1177/1535370218794915

PMCID:: PMC6180406

Abstract Article PDF–742K

Select item 59883655.

Early and Selective Activation and Subsequent Alterations to the Unfolded Protein Response in Down Syndrome Mouse Models

Chiara Lanzillotta, Antonella Tramutola, Shelby Meier, Frederick Schmitt, Eugenio Barone, Marzia Perluigi, Fabio Di Domenico, Jose F. Abisambra

J Alzheimers Dis. Author manuscript; available in PMC 2018 Jun 5.

Published in final edited form as: J Alzheimers Dis. 2018; 62(1): 347–359. doi: 10.3233/JAD-170617

PMCID:: PMC5988365

Abstract Article PDF–5.3M

Select item 59003586.

NLRP3 inflammasome activation in aged macrophages is diminished during Streptococcus pneumoniae infection

Soo Jung Cho, Kristen Rooney, Augustine M. K. Choi, Heather W. Stout-Delgado

Am J Physiol Lung Cell Mol Physiol. 2018 Mar 1; 314(3): L372–L387. Published online 2017 Nov 2. doi: 10.1152/ajplung.00393.2017

Correction in:: Am J Physiol Lung Cell Mol Physiol. 2020 Dec 1; 319(6): L1063–L1064.

PMCID:: PMC5900358

Abstract Article

Select item 56682997.

Palmitate inhibits arthritis by inducing t-bet and gata-3 mRNA degradation in iNKT cells via IRE1α-dependent decay

Jae Sung Ko, Jae Moon Koh, Jae-Seon So, Yoon Kyung Jeon, Hye Young Kim, Doo Hyun Chung

Sci Rep. 2017; 7: 14940. Published online 2017 Nov 2. doi: 10.1038/s41598-017-14780-4

PMCID:: PMC5668299

Abstract Article PDF–3.3M

Select item 53105298.

Molecular signature of anastasis for reversal of apoptosis

Ho Man Tang, C. Conover Talbot Jr, Ming Chiu Fung, Ho Lam Tang

Version 2. F1000Res. 2017; 6: 43. Published online 2017 Feb 9. doi: 10.12688/f1000research.10568.2

PMCID:: PMC5310529

Abstract Article PDF–5.1M

Select item 51422019.

Hepatocellular autophagy modulates the unfolded protein response and fasting-induced steatosis in mice

Wilhelmus J. Kwanten, Yves-Paul Vandewynckel, Wim Martinet, Benedicte Y. De Winter, Peter P. Michielsen, Viviane O. Van Hoof, Ann Driessen, Jean-Pierre Timmermans, Pierre Bedossa, Hans Van Vlierberghe, Sven M. Francque

Am J Physiol Gastrointest Liver Physiol. 2016 Oct 1; 311(4): G599–G609. Published online 2016 Aug 11. doi: 10.1152/ajpgi.00418.2015

PMCID:: PMC5142201

Abstract Article

Select item 482371310.

Novel mechanism of enhancing IRE1α-XBP1 signalling via the PERK-ATF4 pathway

Akio Tsuru, Yasutaka Imai, Michiko Saito, Kenji Kohno

Sci Rep. 2016; 6: 24217. Published online 2016 Apr 7. doi: 10.1038/srep24217

PMCID:: PMC4823713

Abstract Article PDF–892K

Select item 443452111.

Neural growth hormone: regional regulation by estradiol and/or sex chromosome complement in male and female mice

Kayla M Quinnies, Paul J Bonthuis, Erin P Harris, Savera RJ Shetty, Emilie F Rissman

Biol Sex Differ. 2015; 6: 8. Published online 2015 Apr 28. doi: 10.1186/s13293-015-0026-x

PMCID:: PMC4434521

Abstract Article PDF–1.3M

Select item 428720512.

Increased ER stress as a mechanism of retinal neurovasculopathy in mice with severe hyperhomocysteinemia

Amany Tawfik, Sylvia B. Smith

Austin J Clin Ophthalmol. Author manuscript; available in PMC 2015 Jan 8.

Published in final edited form as: Austin J Clin Ophthalmol. 2014 Jun 16; 1(5): 1023. Published online 2014 Jun 16.

PMCID:: PMC4287205

Abstract Article PDF–620K

Select item 402825313.

Overexpression of the IGF-II/M6P Receptor in Mouse Fibroblast Cell Lines Differentially Alters Expression Profiles of Genes Involved in Alzheimer’s Disease-Related Pathology

Yanlin Wang, Gopal Thinakaran, Satyabrata Kar

PLoS One. 2014; 9(5): e98057. Published online 2014 May 20. doi: 10.1371/journal.pone.0098057

PMCID:: PMC4028253

Abstract Article PDF–2.4M

Select item 401834314.

Epigenetic Characterization of the Growth Hormone Gene Identifies SmcHD1 as a Regulator of Autosomal Gene Clusters

Shabnam Massah, Robert Hollebakken, Mark P. Labrecque, Addie M. Kolybaba, Timothy V. Beischlag, Gratien G. Prefontaine

PLoS One. 2014; 9(5): e97535. Published online 2014 May 12. doi: 10.1371/journal.pone.0097535

PMCID:: PMC4018343

Abstract Article PDF–4.6M

Select item 397670615.

Sigma receptor 1 modulates ER stress and Bcl2 in murine retina

Yonju Ha, Arul K. Shanmugam, Shanu Markand, Eric Zorrilla, Vadivel Ganapathy, Sylvia B. Smith

Cell Tissue Res. Author manuscript; available in PMC 2015 Apr 1.

Published in final edited form as: Cell Tissue Res. 2014 Apr; 356(1): 15–27. Published online 2014 Jan 28. doi: 10.1007/s00441-013-1774-8

PMCID:: PMC3976706

Abstract Article PDF–1.6M

Select item 385499416.

PPM1l encodes an inositol requiring-protein 1 (IRE1) specific phosphatase that regulates the functional outcome of the ER stress response

Gang Lu, Asuka Ota, Shuxun Ren, Sarah Franklin, Christoph D. Rau, Peipei Ping, Timothy F. Lane, Z. Hong Zhou, Karen Reue, Aldons J. Lusis, Thomas Vondriska, Yibin Wang

Mol Metab. 2013 Nov; 2(4): 405–416. Published online 2013 Aug 3. doi: 10.1016/j.molmet.2013.07.005

PMCID:: PMC3854994

Abstract Article PDF–3.2M

Select item 378133417.

Temporal clustering of gene expression links the metabolic transcription factor HNF4α to the ER stress-dependent gene regulatory network

Angela M. Arensdorf, Diane DeZwaan McCabe, Randal J. Kaufman, D. Thomas Rutkowski

Front Genet. 2013; 4: 188. Prepublished online 2013 Sep 2. Published online 2013 Sep 24. doi: 10.3389/fgene.2013.00188

PMCID:: PMC3781334

Abstract Article PDF–1.4M

Select item 322639918.

Proteomic Profiling of Adipose Tissue from Zmpste24^−/− Mice, a Model of Lipodystrophy and Premature Aging, Reveals Major Changes in Mitochondrial Function and Vimentin Processing

Juan R. Peinado, Pedro M. Quirós, Marina R. Pulido, Guillermo Mariño, Maria L. Martínez-Chantar, Rafael Vázquez-Martínez, José M. P. Freije, Carlos López-Otín, María M. Malagón

Mol Cell Proteomics. 2011 Nov; 10(11): M111.008094. Published online 2011 Aug 9. doi: 10.1074/mcp.M111.008094

PMCID:: PMC3226399

Abstract Article PDF–3.2M

Select item 316444919.

Mannose-6-phosphate regulates destruction of lipid-linked oligosaccharides

Ningguo Gao, Jie Shang, Dang Huynh, Vijaya L. Manthati, Carolina Arias, Heather P. Harding, Randal J. Kaufman, Ian Mohr, David Ron, John R. Falck, Mark A. Lehrman

Mol Biol Cell. 2011 Sep 1; 22(17): 2994–3009. doi: 10.1091/mbc.E11-04-0286