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Select item 70679531.

Complete Genome Sequences of Two Strains of Streptococcus pyogenes Belonging to an Emergent Clade of the Genotype emm89 in Brittany, France

Marie Devaere, Sarrah Boukthir, Séverine Moullec, Emeline Roux, Dominique Lavenier, Ahmad Faili, Samer Kayal

Microbiol Resour Announc. 2020 Mar; 9(11): e00129-20. Published online 2020 Mar 12. doi: 10.1128/MRA.00129-20

PMCID:: PMC7067953

Abstract Article PDF–133K

Select item 69273022.

Unexpected relationships between frequency of antimicrobial resistance, disease phenotype and emm type in group A Streptococcus

Misu A. Sanson, Olga R. Macias, Brittany J. Shah, Blake Hanson, Luis Alberto Vega, Zain Alamarat, Anthony R. Flores

Microb Genom. 2019 Nov; 5(11): e000316. Published online 2019 Nov 22. doi: 10.1099/mgen.0.000316

PMCID:: PMC6927302

Abstract Article PDF–1.9M

Select item 69048763.

The Emergence of Successful Streptococcus pyogenes Lineages through Convergent Pathways of Capsule Loss and Recombination Directing High Toxin Expression

Claire E. Turner, Matthew T. G. Holden, Beth Blane, Carolyne Horner, Sharon J. Peacock, Shiranee Sriskandan

mBio. 2019 Nov-Dec; 10(6): e02521-19. Published online 2019 Dec 10. doi: 10.1128/mBio.02521-19

PMCID:: PMC6904876

Abstract Article PDF–3.7M

Select item 68033114.

Streptococcus pyogenes Transcriptome Changes in the Inflammatory Environment of Necrotizing Fasciitis

Yujiro Hirose, Masaya Yamaguchi, Daisuke Okuzaki, Daisuke Motooka, Hiroshi Hamamoto, Tomoki Hanada, Tomoko Sumitomo, Masanobu Nakata, Shigetada Kawabata

Appl Environ Microbiol. 2019 Nov 1; 85(21): e01428-19. Prepublished online 2019 Aug 30. Published online 2019 Oct 16. doi: 10.1128/AEM.01428-19

PMCID:: PMC6803311

Abstract Article PDF–3.3M

Select item 66097625.

The β‐domain of streptokinase affects several functionalities, including specific/proteolytic activity kinetics

Maryam Rafipour, Malihe Keramati, Mohammad Mehdi Aslani, Arash Arashkia, Farzin Roohvand

FEBS Open Bio. 2019 Jul; 9(7): 1259–1269. Published online 2019 May 30. doi: 10.1002/2211-5463.12657

PMCID:: PMC6609762

Abstract Article PDF–580K

Select item 64310276.

Conserved and specific features of Streptococcus pyogenes and Streptococcus agalactiae transcriptional landscapes

Isabelle Rosinski-Chupin, Elisabeth Sauvage, Agnès Fouet, Claire Poyart, Philippe Glaser

BMC Genomics. 2019; 20: 236. Published online 2019 Mar 22. doi: 10.1186/s12864-019-5613-5

PMCID:: PMC6431027

Abstract Article PDF–2.4M

Select item 63745957.

A Controlled Human Infection Model of Group A Streptococcus Pharyngitis: Which Strain and Why?

Joshua Osowicki, Kristy I. Azzopardi, Liam McIntyre, Tania Rivera-Hernandez, Cheryl-lynn Y. Ong, Ciara Baker, Christine M. Gillen, Mark J. Walker, Pierre R. Smeesters, Mark R. Davies, Andrew C. Steer

mSphere. 2019 Jan-Feb; 4(1): e00647-18. Published online 2019 Feb 13. doi: 10.1128/mSphere.00647-18

PMCID:: PMC6374595

Abstract Article PDF–1.2M

Select item 61201948.

Streptococcal inhibitor of complement (SIC) modulates fibrinolysis and enhances bacterial survival within fibrin clots

Inga-Maria Frick, Oonagh Shannon, Ariane Neumann, Christofer Karlsson, Mats Wikström, Lars Björck

J Biol Chem. 2018 Aug 31; 293(35): 13578–13591. Published online 2018 Jul 12. doi: 10.1074/jbc.RA118.001988

PMCID:: PMC6120194

Abstract Article PDF–1.9M

Select item 60282389.

Human IgG increases virulence of Streptococcus pyogenes through complement evasion

David Ermert, Antonin Weckel, Michal Magda, Matthias Mörgelin, Jutamas Shaughnessy, Peter A. Rice, Lars Björck, Sanjay Ram, Anna M. Blom

J Immunol. Author manuscript; available in PMC 2019 May 15.

Published in final edited form as: J Immunol. 2018 May 15; 200(10): 3495–3505. Published online 2018 Apr 6. doi: 10.4049/jimmunol.1800090

PMCID:: PMC6028238

Abstract Article PDF–3.9M

Select item 601316310.

In silico characterisation of the two-component system regulators of Streptococcus pyogenes

Sean J. Buckley, Peter Timms, Mark R. Davies, David J. McMillan

PLoS One. 2018; 13(6): e0199163. Published online 2018 Jun 21. doi: 10.1371/journal.pone.0199163

PMCID:: PMC6013163

Abstract Article PDF–18M

Select item 596655411.

Group A Streptococcus M1T1 Intracellular Infection of Primary Tonsil Epithelial Cells Dampens Levels of Secreted IL-8 Through the Action of SpyCEP

Amelia T. Soderholm, Timothy C. Barnett, Othmar Korn, Tania Rivera-Hernandez, Lisa M. Seymour, Benjamin L. Schulz, Victor Nizet, Christine A. Wells, Matthew J. Sweet, Mark J. Walker

Front Cell Infect Microbiol. 2018; 8: 160. Published online 2018 May 17. doi: 10.3389/fcimb.2018.00160

PMCID:: PMC5966554

Abstract Article PDF–1.9M

Select item 584574212.

Genome sequence analysis of emm89 Streptococcus pyogenes strains causing infections in Scotland, 2010–2016

Stephen B. Beres, Randall J. Olsen, Matthew Ojeda Saavedra, Roisin Ure, Arlene Reynolds, Diane S. J. Lindsay, Andrew J. Smith, James M. Musser

J Med Microbiol. 2017 Dec; 66(12): 1765–1773. Published online 2017 Nov 3. doi: 10.1099/jmm.0.000622

PMCID:: PMC5845742

Abstract Article PDF–2.6M

Select item 580864913.

Comparative pathogenomic characterization of a non-invasive serotype M71 strain Streptococcus pyogenes NS53 reveals incongruent phenotypic implications from distinct genotypic markers

Yun-Juan Bao, Yang Li, Zhong Liang, Garima Agrahari, Shaun W. Lee, Victoria A. Ploplis, Francis J. Castellino

Pathog Dis. 2017 Jul; 75(5): ftx056. Published online 2017 May 17. doi: 10.1093/femspd/ftx056

PMCID:: PMC5808649

Abstract Article PDF–3.7M

Select item 562475314.

Full Sequencing and Genomic Analysis of Three emm75 Group A Streptococcus Strains Recovered in the Course of an Epidemiological Shift in French Brittany

Aude Rochefort, Sarrah Boukthir, Séverine Moullec, Alexandra Meygret, Yahia Adnani, Dominique Lavenier, Ahmad Faili, Samer Kayal

Genome Announc. 2017 Sep; 5(39): e00957-17. Published online 2017 Sep 28. doi: 10.1128/genomeA.00957-17

PMCID:: PMC5624753

Abstract Article PDF–139K

Select item 560941115.

Complete Genome Sequences of emm111 Type Streptococcus pyogenes Strain GUR, with Antitumor Activity, and Its Derivative Strain GURSA1 with an Inactivated emm Gene

Maria A. Suvorova, Anna N. Tsapieva, Emilie Glad Bak, Valery A. Chereshnev, Ekaterina P. Kiseleva, Alexander N. Suvorov, Manimozhiyan Arumugam

Genome Announc. 2017 Sep; 5(38): e00939-17. Published online 2017 Sep 21. doi: 10.1128/genomeA.00939-17

PMCID:: PMC5609411

Abstract Article PDF–143K

Select item 560594016.

Population and Whole Genome Sequence Based Characterization of Invasive Group A Streptococci Recovered in the United States during 2015

Sopio Chochua, Ben J. Metcalf, Zhongya Li, Joy Rivers, Saundra Mathis, Delois Jackson, Robert E. Gertz, Jr., Velusamy Srinivasan, Ruth Lynfield, Chris Van Beneden, Lesley McGee, Bernard Beall

mBio. 2017 Sep-Oct; 8(5): e01422-17. Published online 2017 Sep 19. doi: 10.1128/mBio.01422-17

PMCID:: PMC5605940

Abstract Article PDF–2.2M

Select item 560360317.

Linoleic and palmitoleic acid block streptokinase-mediated plasminogen activation and reduce severity of invasive group A streptococcal infection

Katharina Rox, Rolf Jansen, Torsten G. Loof, Christine M. Gillen, Steffen Bernecker, Mark J. Walker, Gursharan Singh Chhatwal, Rolf Müller

Sci Rep. 2017; 7: 11798. Published online 2017 Sep 18. doi: 10.1038/s41598-017-11276-z

PMCID:: PMC5603603

Abstract Article PDF–1.5M

Select item 540721118.

Rapid Emergence of a New Clone Impacts the Population at Risk and Increases the Incidence of Type emm89 Group A Streptococcus Invasive Disease

Sarah Teatero, Brenda L. Coleman, Stephen B. Beres, Randall J. Olsen, Christopher Kandel, Olivia Reynolds, Taryn B. T. Athey, James M. Musser, Allison McGeer, Nahuel Fittipaldi

Open Forum Infect Dis. 2017 Spring; 4(2): ofx042. Published online 2017 Mar 4. doi: 10.1093/ofid/ofx042

PMCID:: PMC5407211

Abstract Article PDF–209K

Select item 532848319.

The Transcriptional Regulator CpsY Is Important for Innate Immune Evasion in Streptococcus pyogenes

Luis A. Vega, Kayla M. Valdes, Ganesh S. Sundar, Ashton T. Belew, Emrul Islam, Jacob Berge, Patrick Curry, Steven Chen, Najib M. El-Sayed, Yoann Le Breton, Kevin S. McIver

Infect Immun. 2017 Mar; 85(3): e00925-16. Prepublished online 2016 Dec 19. Published online 2017 Feb 23. doi: 10.1128/IAI.00925-16