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Items: 1 to 20 of 24

1.
Reversible Memory Loss in a Mouse Transgenic Model of Alzheimer's Disease
Linda A. Kotilinek, Brian Bacskai, Marcus Westerman, Takeshi Kawarabayashi, Linda Younkin, Bradley T. Hyman, Steven Younkin, Karen H. Ashe
J Neurosci. 2002 Aug 1; 22(15): 6331–6335. doi: 10.1523/JNEUROSCI.22-15-06331.2002
PMCID:
PMC6758140
AbstractArticlePDF–195K
2.
Curcumin attenuates oxidative stress in RAW264.7 cells by increasing the activity of antioxidant enzymes and activating the Nrf2-Keap1 pathway
Xinyu Lin, Dingping Bai, Zixi Wei, Ying Zhang, Yifan Huang, Hui Deng, Xiaohong Huang
PLoS One. 2019; 14(5): e0216711. Published online 2019 May 21. doi: 10.1371/journal.pone.0216711
PMCID:
PMC6528975
AbstractArticlePDF–1.5M
3.
Downregulation of Keap1 contributes to poor prognosis and Axitinib resistance of renal cell carcinoma via upregulation of Nrf2 expression
Haipeng Huang, Yunhong Wu, Weijin Fu, Xiaoming Wang, Liquan Zhou, Xiaolong Xu, Fu Huang, Yi Wu
Int J Mol Med. 2019 May; 43(5): 2044–2054. Published online 2019 Mar 14. doi: 10.3892/ijmm.2019.4134
PMCID:
PMC6443340
AbstractArticlePDF–1.0M
4.
MicroRNA miR-24-3p Reduces Apoptosis and Regulates Keap1-Nrf2 Pathway in Mouse Cardiomyocytes Responding to Ischemia/Reperfusion Injury
Xu Xiao, Zhigang Lu, Victor Lin, Adam May, Daniel H. Shaw, Zhihao Wang, Briana Che, Kyle Tran, Hongjun Du, Peter X. Shaw
Oxid Med Cell Longev. 2018; 2018: 7042105. Published online 2018 Dec 2. doi: 10.1155/2018/7042105
PMCID:
PMC6304907
AbstractArticlePDF–1.2M
5.
DC32, a Dihydroartemisinin Derivative, Ameliorates Collagen-Induced Arthritis Through an Nrf2-p62-Keap1 Feedback Loop
Menglin Fan, Yanan Li, Chunhua Yao, Xiufeng Liu, Jihua Liu, Boyang Yu
Front Immunol. 2018; 9: 2762. Published online 2018 Nov 27. doi: 10.3389/fimmu.2018.02762
PMCID:
PMC6277526
AbstractArticlePDF–4.9M
6.
The Nrf2 inhibitor brusatol is a potent antitumour agent in an orthotopic mouse model of colorectal cancer
Jonathan P. Evans, Boleslaw K. Winiarski, Paul A. Sutton, Robert P. Jones, Lorenzo Ressel, Carrie A. Duckworth, D. Mark Pritchard, Zhi-Xiu Lin, Fretwell L. Vicky, Elizabeth M. Tweedle, Eithne Costello, Christopher E. Goldring, Ian M. Copple, B. Kevin Park, Daniel H. Palmer, Neil R. Kitteringham
Oncotarget. 2018 Jun 5; 9(43): 27104–27116. Published online 2018 Jun 5. doi: 10.18632/oncotarget.25497
Correction in:
Oncotarget. 2019 Jan 18; 10(6): 685.
PMCID:
PMC6007465
AbstractArticlePDF–6.0M
7.
Nrf2 Deficiency Upregulates Intrarenal Angiotensin-Converting Enzyme-2 and Angiotensin 1-7 Receptor Expression and Attenuates Hypertension and Nephropathy in Diabetic Mice
Shuiling Zhao, Anindya Ghosh, Chao-Sheng Lo, Isabelle Chenier, James W. Scholey, Janos G. Filep, Julie R. Ingelfinger, Shao-Ling Zhang, John S. D. Chan
Endocrinology. 2018 Feb; 159(2): 836–852. Published online 2017 Dec 1. doi: 10.1210/en.2017-00752
PMCID:
PMC5774246
AbstractArticle
8.
Insulin Inhibits Nrf2 Gene Expression via Heterogeneous Nuclear Ribonucleoprotein F/K in Diabetic Mice
Anindya Ghosh, Shaaban Abdo, Shuiling Zhao, Chin-Han Wu, Yixuan Shi, Chao-Sheng Lo, Isabelle Chenier, Thierry Alquier, Janos G. Filep, Julie R. Ingelfinger, Shao-Ling Zhang, John S. D. Chan
Endocrinology. 2017 Apr 1; 158(4): 903–919. Published online 2017 Jan 23. doi: 10.1210/en.2016-1576
PMCID:
PMC5460794
AbstractArticle
9.
Sigma 1 Receptor regulates the oxidative stress response in primary retinal Müller glial cells via Nrf2 signaling and system xc−, the Na+-independent glutamate-cystine exchanger
J. Wang, A. Shanmugam, S. Markand, E. Zorrilla, V. Ganapathy, S.B. Smith
Free Radic Biol Med. Author manuscript; available in PMC 2016 Sep 1.
Published in final edited form as: Free Radic Biol Med. 2015 Sep; 86: 25–36. Published online 2015 Apr 25. doi: 10.1016/j.freeradbiomed.2015.04.009
PMCID:
PMC4554890
AbstractArticlePDF–1.4M
10.
Acute-phase protein serum amyloid A3 is a novel paracrine coupling factor that controls bone homeostasis
Roman Thaler, Ines Sturmlechner, Silvia Spitzer, Scott M. Riester, Monika Rumpler, Jochen Zwerina, Klaus Klaushofer, Andre J. van Wijnen, Franz Varga
FASEB J. 2015 Apr; 29(4): 1344–1359. Published online 2014 Dec 9. doi: 10.1096/fj.14-265512
PMCID:
PMC4396610
AbstractArticle
11.
Candidate genes for limiting cholestatic intestinal injury identified by gene expression profiling
Samuel M Alaish, Jennifer Timmons, Alexis Smith, Marguerite S Buzza, Ebony Murphy, Aiping Zhao, Yezhou Sun, Douglas J Turner, Terez Shea-Donahue, Toni M Antalis, Alan Cross, Susan G Dorsey
Physiol Rep. 2013 Sep; 1(4): e00073. Published online 2013 Sep 17. doi: 10.1002/phy2.73
PMCID:
PMC3808870
AbstractArticlePDF–1.2M
12.
Activation of the Nrf2-ARE pathway by siRNA knockdown of Keap1 reduces oxidative stress and provides partial protection from MPTP-mediated neurotoxicity
Tracy P. Williamson, Delinda A. Johnson, Jeffrey A. Johnson
Neurotoxicology. Author manuscript; available in PMC 2013 Jun 1.
Published in final edited form as: Neurotoxicology. 2012 Jun; 33(3): 272–279. Published online 2012 Feb 9. doi: 10.1016/j.neuro.2012.01.015
PMCID:
PMC3521526
AbstractArticlePDF–972K
13.
Regulatory Role of KEAP1 and NRF2 in PPARγ Expression and Chemoresistance in Human Non-small Cell Lung Carcinoma Cells
Lijuan Zhan, Hao Zhang, Qiang Zhang, Courtney G. Woods, Yanyan Chen, Peng Xue, Jian Dong, Erik J. Tokar, Yuanyuan Xu, Yongyong Hou, Jingqi Fu, Kathy Yarborough, Aiping Wang, Weidong Qu, Michael P. Waalkes, Melvin E. Andersen, Jingbo Pi
Free Radic Biol Med. Author manuscript; available in PMC 2013 Aug 15.
Published in final edited form as: Free Radic Biol Med. 2012 Aug 15; 53(4): 758–768. Published online 2012 Jun 7. doi: 10.1016/j.freeradbiomed.2012.05.041
Correction in:
Free Radic Biol Med. 2021 Nov 29
PMCID:
PMC3418425
AbstractArticlePDF–3.4M
14.
TYK2 Kinase Activity Is Required for Functional Type I Interferon Responses In Vivo
Michaela Prchal-Murphy, Christian Semper, Caroline Lassnig, Barbara Wallner, Christian Gausterer, Ingeborg Teppner-Klymiuk, Julianna Kobolak, Simone Müller, Thomas Kolbe, Marina Karaghiosoff, Andras Dinnyés, Thomas Rülicke, Nicole R. Leitner, Birgit Strobl, Mathias Müller
PLoS One. 2012; 7(6): e39141. Published online 2012 Jun 18. doi: 10.1371/journal.pone.0039141
PMCID:
PMC3377589
AbstractArticlePDF–929K
15.
Inhibitor of Nrf2 (INrf2 or Keap1) Protein Degrades Bcl-xL via Phosphoglycerate Mutase 5 and Controls Cellular Apoptosis
Suryakant K. Niture, Anil K. Jaiswal
J Biol Chem. 2011 Dec 30; 286(52): 44542–44556. Published online 2011 Nov 9. doi: 10.1074/jbc.M111.275073
Retraction in:
J Biol Chem. 2014 Aug 8; 289(32): 22019.
PMCID:
PMC3247995
AbstractArticle
16.
Hsp90 Interaction with INrf2(Keap1) Mediates Stress-induced Nrf2 Activation
Suryakant K. Niture, Anil K. Jaiswal
J Biol Chem. 2010 Nov 19; 285(47): 36865–36875. Published online 2010 Sep 23. doi: 10.1074/jbc.M110.175802
Retraction in:
J Biol Chem. 2014 Apr 18; 289(16): 11568.
PMCID:
PMC2978616
AbstractArticle
17.
Deficiency in the Nuclear Factor E2-related Factor-2 Transcription Factor Results in Impaired Adipogenesis and Protects against Diet-induced Obesity
Jingbo Pi, Laura Leung, Peng Xue, Weiping Wang, Yongyong Hou, Dianxin Liu, Einav Yehuda-Shnaidman, Candy Lee, Jackie Lau, Theodore W. Kurtz, Jefferson Y. Chan
J Biol Chem. 2010 Mar 19; 285(12): 9292–9300. Published online 2010 Jan 20. doi: 10.1074/jbc.M109.093955
PMCID:
PMC2838347
AbstractArticlePDF–2.0M
18.
Novel design and controls for focused DNA microarrays: applications in quality assurance/control and normalization for the Health Canada ToxArray™
Carole L Yauk, Andrew Williams, Sherri Boucher, Lynn M Berndt, Gu Zhou, Jenny L Zheng, Andrea Rowan-Carroll, Hongyan Dong, Iain B Lambert, George R Douglas, Craig L Parfett
BMC Genomics. 2006; 7: 266. Published online 2006 Oct 19. doi: 10.1186/1471-2164-7-266
PMCID:
PMC1635050
AbstractArticlePDF–567K
19.
Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain
Ken Itoh, Nobunao Wakabayashi, Yasutake Katoh, Tetsuro Ishii, Kazuhiko Igarashi, James Douglas Engel, Masayuki Yamamoto
Genes Dev. 1999 Jan 1; 13(1): 76–86. doi: 10.1101/gad.13.1.76
PMCID:
PMC316370
AbstractArticlePDF–1.7M
20.
RIKEN Integrated Sequence Analysis (RISA) System—384-Format Sequencing Pipeline with 384 Multicapillary Sequencer
Kazuhiro Shibata, Masayoshi Itoh, Katsunori Aizawa, Sumiharu Nagaoka, Nobuya Sasaki, Piero Carninci, Hideaki Konno, Junichi Akiyama, Katsuo Nishi, Tokuji Kitsunai, Hideo Tashiro, Mari Itoh, Noriko Sumi, Yoshiyuki Ishii, Shin Nakamura, Makoto Hazama, Tsutomu Nishine, Akira Harada, Rintaro Yamamoto, Hiroyuki Matsumoto, Sumito Sakaguchi, Takashi Ikegami, Katsuya Kashiwagi, Syuji Fujiwake, Kouji Inoue, Yoshiyuki Togawa, Masaki Izawa, Eiji Ohara, Masanori Watahiki, Yuko Yoneda, Tomokazu Ishikawa, Kaori Ozawa, Takumi Tanaka, Shuji Matsuura, Jun Kawai, Yasushi Okazaki, Masami Muramatsu, Yorinao Inoue, Akira Kira, Yoshihide Hayashizaki
Genome Res. 2000 Nov; 10(11): 1757–1771. doi: 10.1101/gr.152600
PMCID:
PMC310992
AbstractArticlePDF–3.4M

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