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Select item 69996211.

Loss of autophagy in chondrocytes causes severe growth retardation

Yoji Horigome, Hiroko Ida-Yonemochi, Satoshi Waguri, Shunichi Shibata, Naoto Endo, Masaaki Komatsu

Autophagy. 2020; 16(3): 501–511. Published online 2019 Jun 16. doi: 10.1080/15548627.2019.1628541

PMCID:: PMC6999621

Abstract Article PDF–3.5M

Select item 69233962.

Requirement for p62 acetylation in the aggregation of ubiquitylated proteins under nutrient stress

Zhiyuan You, Wen-Xue Jiang, Ling-Yun Qin, Zhou Gong, Wei Wan, Jin Li, Yusha Wang, Hongtao Zhang, Chao Peng, Tianhua Zhou, Chun Tang, Wei Liu

Nat Commun. 2019; 10: 5792. Published online 2019 Dec 19. doi: 10.1038/s41467-019-13718-w

PMCID:: PMC6923396

Abstract Article PDF–4.1M

Select item 69005163.

The proteasome regulator PI31 is required for protein homeostasis, synapse maintenance, and neuronal survival in mice

Adi Minis, Jose A. Rodriguez, Avi Levin, Kai Liu, Eve-Ellen Govek, Mary E. Hatten, Hermann Steller

Proc Natl Acad Sci U S A. 2019 Dec 3; 116(49): 24639–24650. Published online 2019 Nov 21. doi: 10.1073/pnas.1911921116

PMCID:: PMC6900516

Abstract Article PDF–2.7M

Select item 67488244.

A critical role of VMP1 in lipoprotein secretion

Hideaki Morishita, Yan G Zhao, Norito Tamura, Taki Nishimura, Yuki Kanda, Yuriko Sakamaki, Mitsuyo Okazaki, Dongfang Li, Noboru Mizushima

eLife. 2019; 8: e48834. Published online 2019 Sep 17. doi: 10.7554/eLife.48834

PMCID:: PMC6748824

Abstract Article PDF–4.2M

Select item 65023185.

Meiotic gatekeeper STRA8 suppresses autophagy by repressing Nr1d1 expression during spermatogenesis in mice

Ianina C. Ferder, Leslie Fung, Yasuyo Ohguchi, Xiaoyu Zhang, Kara G. Lassen, Diane Capen, Dennis Brown, Ramnik J. Xavier, Ning Wang

PLoS Genet. 2019 May; 15(5): e1008084. Published online 2019 May 6. doi: 10.1371/journal.pgen.1008084

PMCID:: PMC6502318

Abstract Article PDF–7.5M

Select item 64508926.

Autophagy regulates lipid metabolism through selective turnover of NCoR1

Tetsuya Saito, Akiko Kuma, Yuki Sugiura, Yoshinobu Ichimura, Miki Obata, Hiroshi Kitamura, Shujiro Okuda, Hyeon-Cheol Lee, Kazutaka Ikeda, Yumi Kanegae, Izumu Saito, Johan Auwerx, Hozumi Motohashi, Makoto Suematsu, Tomoyoshi Soga, Takehiko Yokomizo, Satoshi Waguri, Noboru Mizushima, Masaaki Komatsu

Nat Commun. 2019; 10: 1567. Published online 2019 Apr 5. doi: 10.1038/s41467-019-08829-3

PMCID:: PMC6450892

Abstract Article PDF–4.3M

Select item 61816347.

Deficiency of type 2 iodothyronine deiodinase reduces necroptosis activity and oxidative stress responses in retinas of Leber congenital amaurosis model mice

Fan Yang, Hongwei Ma, Michael R. Butler, Xi-Qin Ding

FASEB J. 2018 Nov; 32(11): 6316–6329. Published online 2018 Jun 6. doi: 10.1096/fj.201800484RR

PMCID:: PMC6181634

Abstract Article

Select item 60186358.

N-Acyldopamine induces aggresome formation without proteasome inhibition and enhances protein aggregation via p62/SQSTM1 expression

Gen Matsumoto, Tomonao Inobe, Takanori Amano, Kiyohito Murai, Nobuyuki Nukina, Nozomu Mori

Sci Rep. 2018; 8: 9585. Published online 2018 Jun 25. doi: 10.1038/s41598-018-27872-6

PMCID:: PMC6018635

Abstract Article PDF–4.5M

Select item 60054539.

p62/sequestosome 1 deficiency accelerates osteoclastogenesis in vitro and leads to Paget's disease–like bone phenotypes in mice

Frank Zach, Franziska Polzer, Alexandra Mueller, André Gessner

J Biol Chem. 2018 Jun 15; 293(24): 9530–9541. Published online 2018 Mar 19. doi: 10.1074/jbc.RA118.002449

PMCID:: PMC6005453

Abstract Article PDF–4.3M

Select item 596494410.

Atypical Mouse Cerebellar Development Is Caused by Ectopic Expression of the Forkhead Box Transcription Factor HNF-3β

Heping Zhou, Douglas E. Hughes, Michael L. Major, Kyung Yoo, Christine Pesold, Robert H. Costa

Gene Expr. 2001; 9(4-5): 217–236. Published online 2018 May 23. doi: 10.3727/000000001783992597

PMCID:: PMC5964944

Abstract Article PDF–419K

Select item 595410311.

Acute Noise Exposure Is Associated With Intrinsic Apoptosis in Murine Central Auditory Pathway

Moritz Gröschel, Dietmar Basta, Arne Ernst, Birgit Mazurek, Agnieszka J. Szczepek

Front Neurosci. 2018; 12: 312. Published online 2018 May 9. doi: 10.3389/fnins.2018.00312

PMCID:: PMC5954103

Abstract Article PDF–1.4M

Select item 589337912.

Aberrant subcellular localization of SQSTM1/p62 contributes to increased vulnerability to proteotoxic stress recovery in Huntington’s disease

Ningjing Huang, Christine Erie, Michael L. Lu, Jianning Wei

Mol Cell Neurosci. Author manuscript; available in PMC 2019 Apr 1.

Published in final edited form as: Mol Cell Neurosci. 2018 Apr; 88: 43–52. Published online 2017 Dec 12. doi: 10.1016/j.mcn.2017.12.005

PMCID:: PMC5893379

Abstract Article PDF–2.4M

Select item 579607413.

The Effects of Kaempferol-Inhibited Autophagy on Osteoclast Formation

Chang-Ju Kim, Sang-Hun Shin, Bok-Joo Kim, Chul-Hoon Kim, Jung-Han Kim, Hae-Mi Kang, Bong-Soo Park, In-Ryoung Kim

Int J Mol Sci. 2018 Jan; 19(1): 125. Published online 2018 Jan 2. doi: 10.3390/ijms19010125

PMCID:: PMC5796074

Abstract Article PDF–2.9M

Select item 574221814.

Sequestosome 1 Deficiency Delays, but Does Not Prevent Brain Damage Formation Following Acute Brain Injury in Adult Mice

Anne Sebastiani, Christina Gölz, Philipp G. Sebastiani, Wiesia Bobkiewicz, Christian Behl, Thomas Mittmann, Serge C. Thal, Kristin Engelhard

Front Neurosci. 2017; 11: 678. Published online 2017 Dec 19. doi: 10.3389/fnins.2017.00678

PMCID:: PMC5742218

Abstract Article PDF–1.5M

Select item 568017215.

The liver protection of propylene glycol alginate sodium sulfate preconditioning against ischemia reperfusion injury: focusing MAPK pathway activity

Shizan Xu, Peiqin Niu, Kan Chen, Yujing Xia, Qiang Yu, Ning Liu, Jingjing Li, Sainan Li, Liwei Wu, Jiao Feng, Wenwen Wang, Xiya Lu, Tong Liu, Fan Wang, Weiqi Dai, Xiaoming Fan, Wenhui Mo, Ling Xu, Chuanyong Guo

Sci Rep. 2017; 7: 15175. Published online 2017 Nov 9. doi: 10.1038/s41598-017-15521-3

PMCID:: PMC5680172

Abstract Article PDF–7.0M

Select item 565511716.

Specific Physical Exercise Improves Energetic Metabolism in the Skeletal Muscle of Amyotrophic-Lateral- Sclerosis Mice

Céline Desseille, Séverine Deforges, Olivier Biondi, Léo Houdebine, Domenico D’amico, Antonin Lamazière, Cédric Caradeuc, Gildas Bertho, Gaëlle Bruneteau, Laure Weill, Jean Bastin, Fatima Djouadi, François Salachas, Philippe Lopes, Christophe Chanoine, Charbel Massaad, Frédéric Charbonnier

Front Mol Neurosci. 2017; 10: 332. Published online 2017 Oct 20. doi: 10.3389/fnmol.2017.00332

PMCID:: PMC5655117

Abstract Article PDF–3.2M

Select item 550163417.

Salidroside pretreatment attenuates apoptosis and autophagy during hepatic ischemia–reperfusion injury by inhibiting the mitogen-activated protein kinase pathway in mice

Jiao Feng, Qinghui Zhang, Wenhui Mo, Liwei Wu, Sainan Li, Jingjing Li, Tong Liu, Shizan Xu, Xiaoming Fan, Chuanyong Guo

Drug Des Devel Ther. 2017; 11: 1989–2006. Published online 2017 Jul 3. doi: 10.2147/DDDT.S136792

PMCID:: PMC5501634

Abstract Article PDF–13M

Select item 496813018.

c-Jun N-terminal kinase-mediated Rubicon expression enhances hepatocyte lipoapoptosis and promotes hepatocyte ballooning

Akiko Suzuki, Keisuke Kakisaka, Yuji Suzuki, Ting Wang, Yasuhiro Takikawa

World J Gastroenterol. 2016 Jul 28; 22(28): 6509–6519. Published online 2016 Jul 28. doi: 10.3748/wjg.v22.i28.6509

PMCID:: PMC4968130

Abstract Article PDF–1.5M

Select item 485029119.

Protein Kinase C ζ Interacts with a Novel Binding Region of Gαq to Act as a Functional Effector

Guzmán Sánchez-Fernández, Sofía Cabezudo, Álvaro Caballero, Carlota García-Hoz, Gregory G. Tall, Javier Klett, Stephen W. Michnick, Federico Mayor, Jr., Catalina Ribas

J Biol Chem. 2016 Apr 29; 291(18): 9513–9525. Published online 2016 Feb 17. doi: 10.1074/jbc.M115.684308