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Select item 69100841.

LSD1-Mediated Demethylation of H3K4me2 Is Required for the Transition from Late Progenitor to Differentiated Mouse Rod Photoreceptor

Evgenya Y. Popova, Carolina Pinzon-Guzman, Anna C. Salzberg, Samuel Shao-Min Zhang, Colin J. Barnstable

Mol Neurobiol. Author manuscript; available in PMC 2019 Dec 13.

Published in final edited form as: Mol Neurobiol. 2016 Sep; 53(7): 4563–4581. Published online 2015 Aug 23. doi: 10.1007/s12035-015-9395-8

PMCID:: PMC6910084

Abstract Article PDF–3.2M

Select item 68305752.

GLUCOCORTICOIDS INHIBIT NOTCH TARGET GENE EXPRESSION IN OSTEOBLASTS

Stefano Zanotti, Jungeun Yu, Suyash Adhikari, Ernesto Canalis

J Cell Biochem. Author manuscript; available in PMC 2019 Nov 5.

Published in final edited form as: J Cell Biochem. 2018 Jul; 119(7): 6016–6023. Published online 2018 Mar 25. doi: 10.1002/jcb.26798

PMCID:: PMC6830575

Abstract Article PDF–760K

Select item 66367833.

Sox2 and FGF20 interact to regulate organ of Corti hair cell and supporting cell development in a spatially-graded manner

Lu M. Yang, Kathryn S. E. Cheah, Sung-Ho Huh, David M. Ornitz

PLoS Genet. 2019 Jul; 15(7): e1008254. Published online 2019 Jul 5. doi: 10.1371/journal.pgen.1008254

PMCID:: PMC6636783

Abstract Article PDF–8.4M

Select item 66324684.

NFIA Controls Telencephalic Progenitor Cell Differentiation through Repression of the Notch Effector Hes1

Michael Piper, Guy Barry, John Hawkins, Sharon Mason, Charlotta Lindwall, Erica Little, Anindita Sarkar, Aaron G. Smith, Randal X. Moldrich, Glen M. Boyle, Shubha Tole, Richard M. Gronostajski, Timothy L. Bailey, Linda J. Richards

J Neurosci. 2010 Jul 7; 30(27): 9127–9139. doi: 10.1523/JNEUROSCI.6167-09.2010

PMCID:: PMC6632468

Abstract Article PDF–4.7M

Select item 66292405.

Tie2 regulates endocardial sprouting and myocardial trabeculation

Xianghu Qu, Cristina Harmelink, H. Scott Baldwin

JCI Insight. 2019 Jul 11; 4(13): e96002. Published online 2019 Jul 11. doi: 10.1172/jci.insight.96002

PMCID:: PMC6629240

Abstract Article PDF–60M

Select item 64134106.

NOTCH Signaling Is Activated through Mechanical Strain in Human Bone Marrow-Derived Mesenchymal Stromal Cells

Fani Ziouti, Regina Ebert, Maximilian Rummler, Melanie Krug, Sigrid Müller-Deubert, Martin Lüdemann, Franz Jakob, Bettina M. Willie, Franziska Jundt

Stem Cells Int. 2019; 2019: 5150634. Published online 2019 Feb 26. doi: 10.1155/2019/5150634

PMCID:: PMC6413410

Abstract Article PDF–1.4M

Select item 61309327.

The lateral meningocele syndrome mutation causes marked osteopenia in mice

Ernesto Canalis, Jungeun Yu, Lauren Schilling, Siu-Pok Yee, Stefano Zanotti

J Biol Chem. 2018 Sep 7; 293(36): 14165–14177. Published online 2018 Jul 24. doi: 10.1074/jbc.RA118.004242

PMCID:: PMC6130932

Abstract Article PDF–4.4M

Select item 60838688.

MICE HARBORING A HAJDU CHENEY SYNDROME MUTATION ARE SENSITIZED TO OSTEOARTHRITIS

S. Zanotti, J. Yu, D. Bridgewater, J.M. Wolf, E. Canalis

Bone. Author manuscript; available in PMC 2019 Sep 1.

Published in final edited form as: Bone. 2018 Sep; 114: 198–205. Published online 2018 Jun 22. doi: 10.1016/j.bone.2018.06.020

PMCID:: PMC6083868

Abstract Article PDF–999K

Select item 55684809.

PARATHYROID HORMONE INHIBITS NOTCH SIGNALING IN OSTEOBLASTS AND OSTEOCYTES

Stefano Zanotti, Ernesto Canalis

Bone. Author manuscript; available in PMC 2018 Oct 1.

Published in final edited form as: Bone. 2017 Oct; 103: 159–167. Published online 2017 Jul 1. doi: 10.1016/j.bone.2017.06.027

PMCID:: PMC5568480

Abstract Article PDF–765K

Select item 551937210.

Sustained Notch2 signaling in osteoblasts, but not in osteoclasts, is linked to osteopenia in a mouse model of Hajdu-Cheney syndrome

Stefano Zanotti, Jungeun Yu, Archana Sanjay, Lauren Schilling, Chris Schoenherr, Aris N. Economides, Ernesto Canalis

J Biol Chem. 2017 Jul 21; 292(29): 12232–12244. Published online 2017 Jun 7. doi: 10.1074/jbc.M117.786129

PMCID:: PMC5519372

Abstract Article PDF–2.9M

Select item 546080111.

An Antibody to Notch2 Reverses the Osteopenic Phenotype of Hajdu-Cheney Mutant Male Mice

Ernesto Canalis, Archana Sanjay, Jungeun Yu, Stefano Zanotti

Endocrinology. 2017 Apr 1; 158(4): 730–742. Published online 2017 Jan 31. doi: 10.1210/en.2016-1787

PMCID:: PMC5460801

Abstract Article

Select item 542419912.

Hairy and Enhancer of Split-related with YRPW Motif-Like (HeyL) is Dispensable for Bone Remodeling in Mice

Ernesto Canalis, Stefano Zanotti

J Cell Biochem. Author manuscript; available in PMC 2018 Jul 1.

Published in final edited form as: J Cell Biochem. 2017 Jul; 118(7): 1819–1826. Published online 2017 Mar 9. doi: 10.1002/jcb.25859

PMCID:: PMC5424199

Abstract Article PDF–529K

Select item 477769213.

THE DMP1-SOST TRANSGENE INTERACTS WITH AND DOWNREGULATES THE DMP1-CRE TRANSGENE AND THE ROSA^NOTCH ALLELE

Stefano Zanotti, Ernesto Canalis

J Cell Biochem. Author manuscript; available in PMC 2017 May 1.

Published in final edited form as: J Cell Biochem. 2016 May; 117(5): 1222–1232. Published online 2015 Oct 20. doi: 10.1002/jcb.25405

PMCID:: PMC4777692

Abstract Article PDF–1.4M

Select item 472625314.

Canonical Notch signaling plays an instructive role in auditory supporting cell development

Dean P. Campbell, Elena Chrysostomou, Angelika Doetzlhofer

Sci Rep. 2016; 6: 19484. Published online 2016 Jan 20. doi: 10.1038/srep19484

PMCID:: PMC4726253

Abstract Article PDF–3.2M

Select item 472243615.

Hajdu Cheney Mouse Mutants Exhibit Osteopenia, Increased Osteoclastogenesis, and Bone Resorption

Ernesto Canalis, Lauren Schilling, Siu-Pok Yee, Sun-Kyeong Lee, Stefano Zanotti

J Biol Chem. 2016 Jan 22; 291(4): 1538–1551. Published online 2015 Dec 1. doi: 10.1074/jbc.M115.685453

PMCID:: PMC4722436

Abstract Article PDF–5.3M

Select item 471903016.

Canonical Notch activation in osteocytes causes osteopetrosis

Ernesto Canalis, David Bridgewater, Lauren Schilling, Stefano Zanotti

Am J Physiol Endocrinol Metab. 2016 Jan 15; 310(2): E171–E182. Published online 2015 Nov 17. doi: 10.1152/ajpendo.00395.2015

PMCID:: PMC4719030

Abstract Article

Select item 465716717.

The Numb/p53 circuitry couples replicative self-renewal and tumor suppression in mammary epithelial cells

Daniela Tosoni, Silvia Zecchini, Marco Coazzoli, Ivan Colaluca, Giovanni Mazzarol, Alicia Rubio, Michele Caccia, Emanuele Villa, Olav Zilian, Pier Paolo Di Fiore, Salvatore Pece

J Cell Biol. 2015 Nov 23; 211(4): 845–862. doi: 10.1083/jcb.201505037

PMCID:: PMC4657167

Abstract Article PDF–13M

Select item 421453518.

Loss of the Podocyte-Expressed Transcription Factor Tcf21/Pod1 Results in Podocyte Differentiation Defects and FSGS

Yoshiro Maezawa, Tuncer Onay, Rizaldy P. Scott, Lindsay S. Keir, Henrik Dimke, Chengjin Li, Vera Eremina, Yuko Maezawa, Marie Jeansson, Jingdong Shan, Matthew Binnie, Moshe Lewin, Asish Ghosh, Jeffrey H. Miner, Seppo J. Vainio, Susan E. Quaggin

J Am Soc Nephrol. 2014 Nov; 25(11): 2459–2470. Published online 2014 Jun 5. doi: 10.1681/ASN.2013121307