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Items: 1 to 20 of 61

1.
Quadruped Gait and Regulation of Apoptotic Factors in Tibiofemoral Joints following Intra-Articular rhPRG4 Injection in Prg4 Null Mice
Daniel S. Yang, Edward E. Dickerson, Ling X. Zhang, Holly Richendrfer, Padmini N. Karamchedu, Gary J. Badger, Tannin A. Schmidt, Alger M. Fredericks, Khaled A. Elsaid, Gregory D. Jay
Int J Mol Sci. 2022 Apr; 23(8): 4245. Published online 2022 Apr 12. doi: 10.3390/ijms23084245
PMCID:
PMC9025840
AbstractArticlePDF–2.7M
2.
Proteoglycan-4 is an essential regulator of synovial macrophage polarization and inflammatory macrophage joint infiltration
Marwa Qadri, Gregory D. Jay, Ling X. Zhang, Tannin A. Schmidt, Jennifer Totonchy, Khaled A. Elsaid
Arthritis Res Ther. 2021; 23: 241. Published online 2021 Sep 14. doi: 10.1186/s13075-021-02621-9
Correction in:
Arthritis Res Ther. 2021; 23: 276.
PMCID:
PMC8439011
AbstractArticlePDF–2.8M
3.
Prg4 prevents osteoarthritis induced by dominant-negative interference of TGF-ß signaling in mice
Robert Dalton Chavez, Philip Sohn, Rosa Serra
PLoS One. 2019; 14(1): e0210601. Published online 2019 Jan 10. doi: 10.1371/journal.pone.0210601
PMCID:
PMC6328116
AbstractArticlePDF–3.2M
4.
Superficial zone cellularity is deficient in mice lacking lubricin: a stereoscopic analysis
Naga Padmini Karamchedu, Josef N. Tofte, Kimberly A. Waller, Ling X. Zhang, Tarpit K. Patel, Gregory D. Jay
Arthritis Res Ther. 2016; 18: 64. Published online 2016 Mar 14. doi: 10.1186/s13075-016-0967-4
PMCID:
PMC5477516
AbstractArticlePDF–3.6M
5.
Osteophyte formation and matrix mineralization in a TMJ osteoarthritis mouse model are associated with ectopic hedgehog signaling
Till E. Bechtold, Cheri Saunders, Rebekah S. Decker, Hyo-Bin Um, Naiga Cottingham, Imad Salhab, Naito Kurio, Paul C. Billings, Maurizio Pacifici, Hyun-Duck Nah, Eiki Koyama
Matrix Biol. Author manuscript; available in PMC 2017 May 1.
Published in final edited form as: Matrix Biol. 2016 May-Jul; 52-54: 339–354. Published online 2016 Mar 3. doi: 10.1016/j.matbio.2016.03.001
PMCID:
PMC4875867
AbstractArticlePDF–2.6M
6.
Excess BMP Signaling in Heterotopic Cartilage Forming in Prg4-null TMJ Discs
T.E. Bechtold, C. Saunders, C. Mundy, H. Um, R.S. Decker, I. Salhab, N. Kurio, P.C. Billings, M. Pacifici, H.D. Nah, E. Koyama
J Dent Res. 2016 Mar; 95(3): 292–301. Published online 2015 Nov 3. doi: 10.1177/0022034515613508
PMCID:
PMC4766954
AbstractArticlePDF–5.2M
7.
Lubricin Deficiency in the Murine Lumbar Intervertebral Disc Results in Elevated Torsional Apparent Modulus
Erin Teeple, Koosha Aslani, Matthew R. Shalvoy, Jade E. Medrano, Ling Zhang, Jason T. Machan, Braden C. Fleming, Gregory D. Jay
J Biomech. Author manuscript; available in PMC 2016 Jul 16.
Published in final edited form as: J Biomech. 2015 Jul 16; 48(10): 2210–2213. Published online 2015 Apr 3. doi: 10.1016/j.jbiomech.2015.03.029
PMCID:
PMC4492848
AbstractArticlePDF–480K
8.
Lubricin is Required for the Structural Integrity and Post-natal Maintenance of TMJ
E. Koyama, C. Saunders, I. Salhab, R.S. Decker, I. Chen, H. Um, M. Pacifici, H.D. Nah
J Dent Res. 2014 Jul; 93(7): 663–670. doi: 10.1177/0022034514535807
PMCID:
PMC4107552
AbstractArticlePDF–2.4M
9.
The mechanical properties of tail tendon fascicles from lubricin knockout, wild type and heterozygous mice
John Reuvers, Andrew R. Thoreson, Chunfeng Zhao, Ling Zhang, Gregory D. Jay, Kai-Nan An, Matthew L. Warman, Peter C. Amadio
J Struct Biol. Author manuscript; available in PMC 2014 Feb 3.
Published in final edited form as: J Struct Biol. 2011 Oct; 176(1): 41–45. Published online 2011 Jul 29. doi: 10.1016/j.jsb.2011.07.013
PMCID:
PMC3910539
AbstractArticlePDF–4.7M
10.
Mechanical motion promotes expression of Prg4 in articular cartilage via multiple CREB-dependent, fluid flow shear stress-induced signaling pathways
Hiroyasu Ogawa, Elena Kozhemyakina, Han-Hwa Hung, Alan J. Grodzinsky, Andrew B. Lassar
Genes Dev. 2014 Jan 15; 28(2): 127–139. doi: 10.1101/gad.231969.113
PMCID:
PMC3909787
AbstractArticlePDF–1.8M
11.
The Effect of Lubricin on the Gliding Resistance of Mouse Intrasynovial Tendon
Masanori Hayashi, Chunfeng Zhao, Andrew R. Thoreson, Takako Chikenji, Gregory D. Jay, Kai-Nan An, Peter C. Amadio
PLoS One. 2013; 8(12): e83836. Published online 2013 Dec 13. doi: 10.1371/journal.pone.0083836
PMCID:
PMC3862798
AbstractArticlePDF–2.9M
12.
Role of lubricin and boundary lubrication in the prevention of chondrocyte apoptosis
Kimberly A. Waller, Ling X. Zhang, Khaled A. Elsaid, Braden C. Fleming, Matthew L. Warman, Gregory D. Jay
Proc Natl Acad Sci U S A. 2013 Apr 9; 110(15): 5852–5857. Published online 2013 Mar 25. doi: 10.1073/pnas.1219289110
PMCID:
PMC3625316
AbstractArticlePDF–724K
13.
Loss of Cartilage Structure, Stiffness, and Frictional Properties in Mice Lacking PRG4
Jeffrey M Coles, Ling Zhang, Jason J Blum, Matthew L Warman, Gregory D Jay, Farshid Guilak, Stefan Zauscher
Arthritis Rheum. 2010 Jun; 62(6): 1666–1674. doi: 10.1002/art.27436
PMCID:
PMC2943386
AbstractArticlePDF–400K
14.
Association between friction and wear in diarthrodial joints lacking lubricin
Gregory D Jay, Jahn R Torres, David K Rhee, Heikki J Helminen, Mika M Hytinnen, Chung-Ja Cha, Khaled Elsaid, Kyung-Suk Kim, Yajun Cui, Matthew L Warman
Arthritis Rheum. 2007 Nov; 56(11): 3662–3669. doi: 10.1002/art.22974
PMCID:
PMC2688668
AbstractArticlePDF–807K
15.
RSPO2 defines a distinct undifferentiated progenitor in the tendon/ligament and suppresses ectopic ossification
Naohiro Tachibana, Ryota Chijimatsu, Hiroyuki Okada, Takeshi Oichi, Yuki Taniguchi, Yuji Maenohara, Junya Miyahara, Hisatoshi Ishikura, Yasuhide Iwanaga, Yusuke Arino, Kosei Nagata, Hideki Nakamoto, So Kato, Toru Doi, Yoshitaka Matsubayashi, Yasushi Oshima, Asuka Terashima, Yasunori Omata, Fumiko Yano, Shingo Maeda, Shiro Ikegawa, Masahide Seki, Yutaka Suzuki, Sakae Tanaka, Taku Saito
Sci Adv. 2022 Aug; 8(33): eabn2138. Published online 2022 Aug 19. doi: 10.1126/sciadv.abn2138
PMCID:
PMC9390986
AbstractArticlePDF–14M
16.
Wnt/β-catenin signaling contributes to articular cartilage homeostasis through lubricin induction in the superficial zone
Fengjun Xuan, Fumiko Yano, Daisuke Mori, Ryota Chijimatsu, Yuji Maenohara, Hideki Nakamoto, Yoshifumi Mori, Yuma Makii, Takeshi Oichi, Makoto Mark Taketo, Hironori Hojo, Shinsuke Ohba, Ung-il Chung, Sakae Tanaka, Taku Saito
Arthritis Res Ther. 2019; 21: 247. Published online 2019 Nov 27. doi: 10.1186/s13075-019-2041-5
PMCID:
PMC6880374
AbstractArticlePDF–2.3M
17.
Combinatorial Prg4 and Il-1ra Gene Therapy Protects Against Hyperalgesia and Cartilage Degeneration in Post-Traumatic Osteoarthritis
Adrianne Stone, Matthew W. Grol, Merry Z. C. Ruan, Brian Dawson, Yuqing Chen, Ming-Ming Jiang, I-wen Song, Prathap Jayaram, Racel Cela, Francis Gannon, Brendan H. L. Lee
Hum Gene Ther. 2019 Feb 1; 30(2): 225–235. Published online 2019 Feb 8. doi: 10.1089/hum.2018.106
PMCID:
PMC6383580
AbstractArticlePDF–778K
18.
BMP9 stimulates joint regeneration at digit amputation wounds in mice
Ling Yu, Lindsay A. Dawson, Mingquan Yan, Katherine Zimmel, Yu-Lieh Lin, Connor P. Dolan, Manjong Han, Ken Muneoka
Nat Commun. 2019; 10: 424. Published online 2019 Feb 5. doi: 10.1038/s41467-018-08278-4
PMCID:
PMC6363752
AbstractArticlePDF–16M
19.
cAMP attenuates TGF-β’s profibrotic responses in osteoarthritic synoviocytes: involvement of hyaluronan and PRG4
Marwa M. Qadri, Gregory D. Jay, Rennolds S. Ostrom, Ling X. Zhang, Khaled A. Elsaid
Am J Physiol Cell Physiol. 2018 Sep 1; 315(3): C432–C443. Published online 2018 Jun 13. doi: 10.1152/ajpcell.00041.2018
PMCID:
PMC6171038
AbstractArticle
20.
Cartilage-specific deletion of Alk5 gene results in a progressive osteoarthritis-like phenotype in mice
Q. Wang, Q.Y. Tan, W. Xu, H.B. Qi, D. Chen, S. Zhou, Z.H. Ni, L. Kuang, J.Y. Guo, J.L. Huang, X.X. Wang, Z.Q. Wang, N. Su, L. Chen, B. Chen, W.L. Jiang, Y. Gao, H.G. Chen, X.L. Du, Y.L. Xie, L. Chen
Osteoarthritis Cartilage. Author manuscript; available in PMC 2017 Nov 18.
Published in final edited form as: Osteoarthritis Cartilage. 2017 Nov; 25(11): 1868–1879. Published online 2017 Jul 14. doi: 10.1016/j.joca.2017.07.010
PMCID:
PMC5694025
AbstractArticlePDF–1.0M

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