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Items: 1 to 20 of 33

1.
The physiological target for LeuRS translational quality control is norvaline
Nevena Cvetesic, Andrés Palencia, Ivan Halasz, Stephen Cusack, Ita Gruic-Sovulj
EMBO J. 2014 Aug 1; 33(15): 1639–1653. Published online 2014 Jun 16. doi: 10.15252/embj.201488199
PMCID:
PMC4194098
ArticlePDF–2.5M
2.
The Yin and Yang of tRNA: proper binding of acceptor end determines the catalytic balance of editing and aminoacylation
Min Tan, Meng Wang, Xiao-Long Zhou, Wei Yan, Gilbert Eriani, En-Duo Wang
Nucleic Acids Res. 2013 May; 41(10): 5513–5523. Published online 2013 Apr 12. doi: 10.1093/nar/gkt252
PMCID:
PMC3664829
ArticlePDF–4.6M
3.
Functional Segregation of a Predicted “Hinge” Site within the β-Strand Linkers of Escherichia coli Leucyl-tRNA Synthetase
Anjali P. Mascarenhas, Susan A. Martinis
Biochemistry. Author manuscript; available in PMC 2010 Jul 16.
Published in final edited form as: Biochemistry. 2008 Apr 22; 47(16): 4808–4816. Published online 2008 Mar 26. doi: 10.1021/bi702494q
PMCID:
PMC2905381
ArticlePDF–1.8M
4.
tRNA-dependent Pre-transfer Editing by Prokaryotic Leucyl-tRNA Synthetase
Min Tan, Bin Zhu, Xiao-Long Zhou, Ran He, Xin Chen, Gilbert Eriani, En-Duo Wang
J Biol Chem. 2010 Jan 29; 285(5): 3235–3244. Published online 2009 Nov 23. doi: 10.1074/jbc.M109.060616
PMCID:
PMC2823433
ArticlePDF–2.6M
5.
A Glycine Hinge for tRNA-dependent Translocation of Editing Substrates to Prevent Errors by Leucyl-tRNA Synthetase
Anjali P. Mascarenhas, Susan A. Martini
FEBS Lett. Author manuscript; available in PMC 2010 Nov 3.
Published in final edited form as: FEBS Lett. 2009 Nov 3; 583(21): 3443–3447. Published online 2009 Sep 29. doi: 10.1016/j.febslet.2009.09.039
PMCID:
PMC2807821
ArticlePDF–782K
6.
Defects in Transient tRNA Translocation Bypass tRNA Synthetase Quality Control Mechanisms
Rachel A. Hellmann, Susan A. Martinis
J Biol Chem. 2009 Apr 24; 284(17): 11478–11484. doi: 10.1074/jbc.M807395200
PMCID:
PMC2670153
ArticlePDF–607K
7.
CP1-dependent partitioning of pretransfer and posttransfer editing in leucyl-tRNA synthetase
Michal T. Boniecki, Michael T. Vu, Aswini K. Betha, Susan A. Martinis
Proc Natl Acad Sci U S A. 2008 Dec 9; 105(49): 19223–19228. Published online 2008 Nov 19. doi: 10.1073/pnas.0809336105
PMCID:
PMC2614743
ArticlePDF–865K
8.
Isolated CP1 Domain of Escherichia coli Leucyl-tRNA Synthetase is Dependent on Flanking Hinge Motifs for Amino Acid Editing Activity
Aswini K. Betha, Amy M. Williams, Susan A. Martinis
Biochemistry. Author manuscript; available in PMC 2008 Aug 21.
Published in final edited form as: Biochemistry. 2007 May 29; 46(21): 6258–6267. Published online 2007 May 3. doi: 10.1021/bi061965j
PMCID:
PMC2518914
ArticlePDF–2.5M
9.
A Unique Insert of Leucyl-tRNA Synthetase is Required for Aminoacylation and Not Amino Acid Editing
Michael T. Vu, Susan A. Martinis
Biochemistry. Author manuscript; available in PMC 2008 Aug 21.
Published in final edited form as: Biochemistry. 2007 May 1; 46(17): 5170–5176. Published online 2007 Apr 4. doi: 10.1021/bi062078j
PMCID:
PMC2518912
ArticlePDF–2.4M
10.
Amino Acid Toxicities of Escherichia coli That Are Prevented by Leucyl-tRNA Synthetase Amino Acid Editing
Vrajesh A. Karkhanis, Anjali P. Mascarenhas, Susan A. Martinis
J Bacteriol. 2007 Dec; 189(23): 8765–8768. Published online 2007 Sep 21. doi: 10.1128/JB.01215-07
PMCID:
PMC2168938
ArticlePDF–262K
11.
Mutational unmasking of a tRNA-dependent pathway for preventing genetic code ambiguity
Amy M. Williams, Susan A. Martinis
Proc Natl Acad Sci U S A. 2006 Mar 7; 103(10): 3586–3591. Published online 2006 Feb 27. doi: 10.1073/pnas.0507362103
PMCID:
PMC1383500
ArticlePDF–1.1M
12.
The proofreading of hydroxy analogues of leucine and isoleucine by leucyl-tRNA synthetases from E. coli and yeast.
S Englisch, U Englisch, F von der Haar, F Cramer
Nucleic Acids Res. 1986 Oct 10; 14(19): 7529–7539. doi: 10.1093/nar/14.19.7529
PMCID:
PMC311778
ArticlePDF–1.0M
13.
Tertiary structure base pairs between D- and TψC-loops of Escherichia coli tRNALeu play important roles in both aminoacylation and editing
Xing Du, En-Duo Wang
Nucleic Acids Res. 2003 Jun 1; 31(11): 2865–2872. doi: 10.1093/nar/gkg382
PMCID:
PMC156717
ArticlePDF–307K
14.
Acetylation of lysine ϵ-amino groups regulates aminoacyl-tRNA synthetase activity in Escherichia coli
Qing Ye, Quan-Quan Ji, Wei Yan, Fang Yang, En-Duo Wang
J Biol Chem. 2017 Jun 23; 292(25): 10709–10722. Published online 2017 Apr 28. doi: 10.1074/jbc.M116.770826
PMCID:
PMC5481575
ArticlePDF–3.3M
15.
A single residue in LeuRS affecting amino acid specificity and tRNA aminoacylation
Stanley W. Lue, Shana O. Kelley
Biochemistry. Author manuscript; available in PMC 2008 Aug 19.
Published in final edited form as: Biochemistry. 2007 Apr 17; 46(15): 4466–4472. Published online 2007 Mar 23. doi: 10.1021/bi0618215
PMCID:
PMC2518062
ArticlePDF–1.1M
16.
A Flexible Peptide Tether Controls Accessibility of a Unique C-terminal RNA Binding Domain in Leucyl-tRNA Synthetases
Jennifer L. Hsu, Susan A. Martinis
J Mol Biol. Author manuscript; available in PMC 2009 Feb 15.
Published in final edited form as: J Mol Biol. 2008 Feb 15; 376(2): 482–491. Published online 2007 Nov 28. doi: 10.1016/j.jmb.2007.11.065
PMCID:
PMC2270793
ArticlePDF–999K
17.
Molecular cloning and nucleotide sequence of the gene for Escherichia coli leucyl-tRNA synthetase.
M Härtlein, D Madern
Nucleic Acids Res. 1987 Dec 23; 15(24): 10199–10210. doi: 10.1093/nar/15.24.10199
PMCID:
PMC339939
ArticlePDF–1.4M
18.
Isolation and Partial Characterization of Temperature-Sensitive Escherichia coli Mutants with Altered Leucyl- and Seryl-Transfer Ribonucleic Acid Synthetases
B. Low, F. Gates, T. Goldstein, D. Söll
J Bacteriol. 1971 Nov; 108(2): 742–750. doi: 10.1128/jb.108.2.742-750.1971
PMCID:
PMC247134
ArticlePDF–1.1M
19.
Sequence and structural similarities between the leucine-specific binding protein and leucyl-tRNA synthetase of Escherichia coli.
R M Williamson, D L Oxender
Proc Natl Acad Sci U S A. 1990 Jun; 87(12): 4561–4565. doi: 10.1073/pnas.87.12.4561
PMCID:
PMC54156
ArticlePDF–881K
20.
The CP2 Domain of Leucyl-tRNA Synthetase Is Crucial for Amino Acid Activation and Post-transfer Editing
Xiao-Long Zhou, Bin Zhu, En-Duo Wang
J Biol Chem. 2008 Dec 26; 283(52): 36608–36616. doi: 10.1074/jbc.M806745200
PMCID:
PMC2662312
ArticlePDF–602K

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