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Items: 1 to 20 of 39

1.
Transient kinetic analysis of oxidative dealkylation by the direct reversal DNA repair enzyme AlkB
Michael R. Baldwin, Suzanne J. Admiraal, Patrick J. O'Brien
J Biol Chem. 2020 May 22; 295(21): 7317–7326. Published online 2020 Apr 13. doi: 10.1074/jbc.RA120.013517
PMCID:
PMC7247310
AbstractArticlePDF–1.4M
2.
AlkB Dioxygenase Preferentially Repairs Protonated Substrates: SPECIFICITY AGAINST EXOCYCLIC ADDUCTS AND MOLECULAR MECHANISM OF ACTION
Agnieszka M. Maciejewska, Jarosław Poznański, Zuzanna Kaczmarska, Beata Krowisz, Jadwiga Nieminuszczy, Agnieszka Polkowska-Nowakowska, Elżbieta Grzesiuk, Jarosław T. Kuśmierek
J Biol Chem. 2013 Jan 4; 288(1): 432–441. Published online 2012 Nov 12. doi: 10.1074/jbc.M112.353342
PMCID:
PMC3537041
AbstractArticlePDF–1.5M
3.
Iron-Catalyzed Oxidation Intermediates Captured in a DNA Repair Dioxygenase
Chengqi Yi, Guifang Jia, Guanhua Hou, Qing Dai, Wen Zhang, Guanqun Zheng, Xing Jian, Cai-Guang Yang, Qiang Cui, Chuan He
Nature. Author manuscript; available in PMC 2011 May 11.
Published in final edited form as: Nature. 2010 Nov 11; 468(7321): 330–333. doi: 10.1038/nature09497
PMCID:
PMC3058853
AbstractArticlePDF–845K
4.
A Non-Heme Iron-Mediated Chemical Demethylation in DNA and RNA
Chengqi Yi, Cai-Guang Yang, Chuan He
Acc Chem Res. Author manuscript; available in PMC 2010 Aug 12.
Published in final edited form as: Acc Chem Res. 2009 Apr 21; 42(4): 519–529. doi: 10.1021/ar800178j
PMCID:
PMC2920458
AbstractArticlePDF–4.6M
5.
Bioinformatics and functional analysis define four distinct groups of AlkB DNA-dioxygenases in bacteria
Erwin van den Born, Anders Bekkelund, Marivi N. Moen, Marina V. Omelchenko, Arne Klungland, Pål Ø. Falnes
Nucleic Acids Res. 2009 Nov; 37(21): 7124–7136. Published online 2009 Sep 28. doi: 10.1093/nar/gkp774
PMCID:
PMC2790896
AbstractArticlePDF–1.3M
6.
Enzymological and structural studies of the mechanism of promiscuous substrate recognition by the oxidative DNA repair enzyme AlkB
Bomina Yu, John F. Hunt
Proc Natl Acad Sci U S A. 2009 Aug 25; 106(34): 14315–14320. Published online 2009 Aug 11. doi: 10.1073/pnas.0812938106
PMCID:
PMC2725012
AbstractArticlePDF–1.6M
7.
Transcription Increases Methylmethane Sulfonate-Induced Mutations in alkB Strains of Escherichia coli
Douglas Fix, Chandrika Canugovi, Ashok S. Bhagwat
DNA Repair (Amst) Author manuscript; available in PMC 2009 Aug 2.
Published in final edited form as: DNA Repair (Amst). 2008 Aug 2; 7(8): 1289–1297. Published online 2008 Jun 2. doi: 10.1016/j.dnarep.2008.04.008
PMCID:
PMC2569841
AbstractArticlePDF–622K
8.
Dynamic states of the DNA repair enzyme AlkB regulate product release
Boris Bleijlevens, Tara Shivarattan, Emily Flashman, Yi Yang, Pete J Simpson, Pertti Koivisto, Barbara Sedgwick, Christopher J Schofield, Steve J Matthews
EMBO Rep. 2008 Sep; 9(9): 872–877. Published online 2008 Jul 11. doi: 10.1038/embor.2008.120
PMCID:
PMC2529343
AbstractArticlePDF–635K
9.
Direct Repair of the Exocyclic DNA Adduct 1,N6-Ethenoadenine by the DNA Repair AlkB Proteins
Yukiko Mishina, Cai-Guang Yang, Chuan He
J Am Chem Soc. Author manuscript; available in PMC 2008 Jun 19.
Published in final edited form as: J Am Chem Soc. 2005 Oct 26; 127(42): 14594–14595. doi: 10.1021/ja055957m
PMCID:
PMC2432083
ArticlePDF–269K
10.
Oxidative dealkylation DNA repair mediated by the mononuclear non-heme iron AlkB proteins
Yukiko Mishina, Chuan He
J Inorg Biochem. Author manuscript; available in PMC 2008 May 15.
Published in final edited form as: J Inorg Biochem. 2006 Apr; 100(4): 670–678. Published online 2006 Feb 15. doi: 10.1016/j.jinorgbio.2005.12.018
PMCID:
PMC2386269
AbstractArticlePDF–2.8M
11.
Kinetic studies of Escherichia coli AlkB using a new fluorescence-based assay for DNA demethylation
Todd W. Roy, A. S. Bhagwat
Nucleic Acids Res. 2007 Dec; 35(21): e147. Published online 2007 Nov 14. doi: 10.1093/nar/gkm1031
PMCID:
PMC2175350
AbstractArticlePDF–261K
12.
Alleviation of 1,N6-ethanoadenine genotoxicity by the Escherichia coli adaptive response protein AlkB
Lauren E. Frick, James C. Delaney, Cintyu Wong, Catherine L. Drennan, John M. Essigmann
Proc Natl Acad Sci U S A. 2007 Jan 16; 104(3): 755–760. Published online 2007 Jan 9. doi: 10.1073/pnas.0607377104
PMCID:
PMC1783386
AbstractArticlePDF–535K
13.
Alkylating Agents Induce Uvm, a Reca-Independent Inducible Mutagenic Phenomenon in Escherichia Coli
G. Wang, V. A. Palejwala, P. M. Dunman, D. H. Aviv, H. S. Murphy, M. S. Rahman, M. Z. Humayun
Genetics. 1995 Nov; 141(3): 813–823. doi: 10.1093/genetics/141.3.813
PMCID:
PMC1206846
SummaryPDF–4.4M
14.
Repair of 3-methylthymine and 1-methylguanine lesions by bacterial and human AlkB proteins
Pål Ø. Falnes
Nucleic Acids Res. 2004; 32(21): 6260–6267. Published online 2004 Dec 1. doi: 10.1093/nar/gkh964
PMCID:
PMC535673
AbstractArticlePDF–371K
15.
Mutagenesis, genotoxicity, and repair of 1-methyladenine, 3-alkylcytosines, 1-methylguanine, and 3-methylthymine in alkB Escherichia coli
James C. Delaney, John M. Essigmann
Proc Natl Acad Sci U S A. 2004 Sep 28; 101(39): 14051–14056. Published online 2004 Sep 20. doi: 10.1073/pnas.0403489101
PMCID:
PMC521119
AbstractArticlePDF–512K
16.
Substrate specificities of bacterial and human AlkB proteins
Pål Ø. Falnes, Magnar Bjørås, Per Arne Aas, Ottar Sundheim, Erling Seeberg
Nucleic Acids Res. 2004; 32(11): 3456–3461. Published online 2004 Jun 30. doi: 10.1093/nar/gkh655
PMCID:
PMC443531
AbstractArticlePDF–106K
17.
Interaction of human and bacterial AlkB proteins with DNA as probed through chemical cross-linking studies
Yukiko Mishina, Chih-Hui J. Lee, Chuan He
Nucleic Acids Res. 2004; 32(4): 1548–1554. Published online 2004 Mar 5. doi: 10.1093/nar/gkh319
PMCID:
PMC390304
AbstractArticlePDF–329K
18.
Suppression of human DNA alkylation-repair defects by Escherichia coli DNA-repair genes.
L Samson, B Derfler, E A Waldstein
Proc Natl Acad Sci U S A. 1986 Aug; 83(15): 5607–5610. doi: 10.1073/pnas.83.15.5607
PMCID:
PMC386337
SummaryPage BrowsePDF–917K
19.
Defective processing of methylated single-stranded DNA by E. coli alkB mutants
Suneet Dinglay, Sarah C. Trewick, Tomas Lindahl, Barbara Sedgwick
Genes Dev. 2000 Aug 15; 14(16): 2097–2105.
PMCID:
PMC316854
AbstractArticlePDF–658K
20.
A second DNA methyltransferase repair enzyme in Escherichia coli.
G W Rebeck, S Coons, P Carroll, L Samson
Proc Natl Acad Sci U S A. 1988 May; 85(9): 3039–3043. doi: 10.1073/pnas.85.9.3039
PMCID:
PMC280138
SummaryPage BrowsePDF–1.1M

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