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Select item 87516001.

PKMYT1, exacerbating the progression of clear cell renal cell carcinoma, is implied as a biomarker for the diagnosis and prognosis

Juan Chen, Xiaoliang Hua, Heying Chen, Xiangmin Qiu, Haibing Xiao, Shengdong Ge, Chaozhao Liang, Qin Zhou

Aging (Albany NY) 2021 Dec 31; 13(24): 25778–25798. Published online 2021 Dec 27. doi: 10.18632/aging.203759

Correction in:: Aging (Albany NY). 2024 Sep 15; 16(17): 12428.

PMCID:: PMC8751600

Abstract Article PDF–3.0M

Select item 75493262.

Overexpression of PKMYT1 Facilitates Tumor Development and Is Correlated with Poor Prognosis in Clear Cell Renal Cell Carcinoma

Peng Chen, Ziying Zhang, Xiang Chen

Med Sci Monit. 2020; 26: e926755-1–e926755-22. Prepublished online 2020 Aug 19. Published online 2020 Oct 7. doi: 10.12659/MSM.926755

PMCID:: PMC7549326

Abstract Article PDF–5.6M

Select item 70464763.

Systematic expression analysis of WEE family kinases reveals the importance of PKMYT1 in breast carcinogenesis

Yu Liu, Jian Qi, Zhen Dou, Jiliang Hu, Li Lu, Haiming Dai, Hongzhi Wang, Wulin Yang

Cell Prolif. 2020 Feb; 53(2): e12741. Published online 2019 Dec 14. doi: 10.1111/cpr.12741

PMCID:: PMC7046476

Abstract Article PDF–2.7M

Select item 22872904.

Myt1 protein kinase is essential for Golgi and ER assembly during mitotic exit

Hiroyuki Nakajima, Shigenobu Yonemura, Masayuki Murata, Nobuhiro Nakamura, Helen Piwnica-Worms, Eisuke Nishida

J Cell Biol. 2008 Apr 7; 181(1): 89–103. doi: 10.1083/jcb.200708176

PMCID:: PMC2287290

Abstract Article PDF–6.6M

Select item 90460895.

CCNE1 amplification is synthetic lethal with PKMYT1 kinase inhibition

David Gallo, Jordan T. F. Young, Jimmy Fourtounis, Giovanni Martino, Alejandro Álvarez-Quilón, Cynthia Bernier, Nicole M. Duffy, Robert Papp, Anne Roulston, Rino Stocco, Janek Szychowski, Artur Veloso, Hunain Alam, Prasamit S. Baruah, Alexanne Bonneau Fortin, Julian Bowlan, Natasha Chaudhary, Jessica Desjardins, Evelyne Dietrich, Sara Fournier, Chloe Fugère-Desjardins, Theo Goullet de Rugy, Marie-Eve Leclaire, Bingcan Liu, Vivek Bhaskaran, Yael Mamane, Henrique Melo, Olivier Nicolas, Akul Singhania, Rachel K. Szilard, Ján Tkáč, Shou Yun Yin, Stephen J. Morris, Michael Zinda, C. Gary Marshall, Daniel Durocher

Nature. 2022; 604(7907): 749–756. Published online 2022 Apr 20. doi: 10.1038/s41586-022-04638-9

PMCID:: PMC9046089

Abstract Article PDF–15M

Select item 88122666.

Demethylase ALKBH5 suppresses invasion of gastric cancer via PKMYT1 m6A modification

Yiyang Hu, Chunli Gong, Zhibin Li, Jiao Liu, Yang Chen, Yu Huang, Qiang Luo, Sumin Wang, Yu Hou, Shiming Yang, Yufeng Xiao

Mol Cancer. 2022; 21: 34. Published online 2022 Feb 3. doi: 10.1186/s12943-022-01522-y

PMCID:: PMC8812266

Abstract Article PDF–12M

Select item 86381427.

LncRNA PKMYT1AR promotes cancer stem cell maintenance in non-small cell lung cancer via activating Wnt signaling pathway

Yaomei He, Xiulin Jiang, Lincan Duan, Qiuxia Xiong, Yixiao Yuan, Peishen Liu, Liping Jiang, Qiushuo Shen, Song Zhao, Cuiping Yang, Yongbin Chen

Mol Cancer. 2021; 20: 156. Published online 2021 Dec 2. doi: 10.1186/s12943-021-01469-6

PMCID:: PMC8638142

Abstract Article PDF–6.0M

Select item 35453108.

MEK1 inactivates Myt1 to regulate Golgi membrane fragmentation and mitotic entry in mammalian cells

Julien Villeneuve, Margherita Scarpa, Maria Ortega-Bellido, Vivek Malhotra

EMBO J. 2013 Jan 9; 32(1): 72–85. Published online 2012 Dec 14. doi: 10.1038/emboj.2012.329

PMCID:: PMC3545310

Abstract Article PDF–1.2M

Select item 2317829.

The human Myt1 kinase preferentially phosphorylates Cdc2 on threonine 14 and localizes to the endoplasmic reticulum and Golgi complex.

F Liu, J J Stanton, Z Wu, H Piwnica-Worms

Mol Cell Biol. 1997 Feb; 17(2): 571–583. doi: 10.1128/mcb.17.2.571

PMCID:: PMC231782

Summary PDF–617K

Select item 8435410.

Overproduction of Human Myt1 Kinase Induces a G₂ Cell Cycle Delay by Interfering with the Intracellular Trafficking of Cdc2-Cyclin B1 Complexes

Feng Liu, Cynthia Rothblum-Oviatt, Christine E. Ryan, Helen Piwnica-Worms

Mol Cell Biol. 1999 Jul; 19(7): 5113–5123. doi: 10.1128/mcb.19.7.5113

PMCID:: PMC84354

Abstract Article PDF–2.2M

Select item 150502411.

Microtubule-Targeting Drugs Induce Bcl-2 Phosphorylation and Association with Pin1

Nuzhat Pathan, Christine Aime-sempe, Shinichi Kitada, Subrata Haldar, John C Reed

Neoplasia. 2001 Jan; 3(1): 70–79. doi: 10.1038/sj.neo.7900131

PMCID:: PMC1505024

Abstract Article PDF–3.8M

Select item 15133212.

The p53-inducible TSAP6 gene product regulates apoptosis and the cell cycle and interacts with Nix and the Myt1 kinase

Brent J. Passer, Vanessa Nancy-Portebois, Nathalie Amzallag, Sylvie Prieur, Christophe Cans, Aude Roborel de Climens, Giusy Fiucci, Véronique Bouvard, Marcel Tuynder, Laurent Susini, Stéphanie Morchoisne, Virginie Crible, Alexandra Lespagnol, Jean Dausset, Moshe Oren, Robert Amson, Adam Telerman

Proc Natl Acad Sci U S A. 2003 Mar 4; 100(5): 2284–2289. Published online 2003 Feb 26. doi: 10.1073/pnas.0530298100

PMCID:: PMC151332

Abstract Article PDF–496K

Select item 266329713.

c-Jun N-Terminal Kinase 1 Phosphorylates Myt1 To Prevent UVA-Induced Skin Cancer

Hong Seok Choi, Ann M. Bode, Jung-Hyun Shim, Sung-Young Lee, Zigang Dong

Mol Cell Biol. 2009 Apr; 29(8): 2168–2180. Published online 2009 Feb 9. doi: 10.1128/MCB.01508-08

PMCID:: PMC2663297

Abstract Article PDF–2.4M

Select item 31658914.

The essential mitotic peptidyl–prolyl isomerase Pin1 binds and regulates mitosis-specific phosphoproteins

Minhui Shen, P. Todd Stukenberg, Marc W. Kirschner, Kun Ping Lu

Genes Dev. 1998 Mar 1; 12(5): 706–720. doi: 10.1101/gad.12.5.706

PMCID:: PMC316589

Abstract Article PDF–1.1M

Select item 291592215.

A Genome-Wide Association Study of the Metabolic Syndrome in Indian Asian Men

Delilah Zabaneh, David J. Balding

PLoS One. 2010; 5(8): e11961. Published online 2010 Aug 4. doi: 10.1371/journal.pone.0011961

PMCID:: PMC2915922

Abstract Article PDF–315K

Select item 365034316.

Analysis of Protein-Protein Interactions in Cross-talk Pathways Reveals CRKL Protein as a Novel Prognostic Marker in Hepatocellular Carcinoma

Chia-Hung Liu, Tzu-Chi Chen, Gar-Yang Chau, Yi-Hua Jan, Chun-Houh Chen, Chun-Nan Hsu, Kuan-Ting Lin, Yue-Li Juang, Pei-Jung Lu, Hui-Chuan Cheng, Ming-Huang Chen, Chia-Fen Chang, Yu-Shan Ting, Cheng-Yan Kao, Michael Hsiao, Chi-Ying F. Huang

Mol Cell Proteomics. 2013 May; 12(5): 1335–1349. Published online 2013 Feb 8. doi: 10.1074/mcp.O112.020404

PMCID:: PMC3650343

Abstract Article PDF–3.2M

Select item 381740417.

A negative genetic interaction map in isogenic cancer cell lines reveals cancer cell vulnerabilities

Franco J Vizeacoumar, Roland Arnold, Frederick S Vizeacoumar, Megha Chandrashekhar, Alla Buzina, Jordan T F Young, Julian H M Kwan, Azin Sayad, Patricia Mero, Steffen Lawo, Hiromasa Tanaka, Kevin R Brown, Anastasia Baryshnikova, Anthony B Mak, Yaroslav Fedyshyn, Yadong Wang, Glauber C Brito, Dahlia Kasimer, Taras Makhnevych, Troy Ketela, Alessandro Datti, Mohan Babu, Andrew Emili, Laurence Pelletier, Jeff Wrana, Zev Wainberg, Philip M Kim, Robert Rottapel, Catherine A O’Brien, Brenda Andrews, Charles Boone, Jason Moffat

Mol Syst Biol. 2013; 9: 696. Published online 2013 Oct 8. doi: 10.1038/msb.2013.54

PMCID:: PMC3817404

Abstract Article PDF–13M

Select item 666388018.

Spatial proteomics reveal that the protein phosphatase PTP1B interacts with and may modify tyrosine phosphorylation of the rhomboid protease RHBDL4

Kyojiro N. Ikeda, Matthew Freeman

J Biol Chem. 2019 Jul 26; 294(30): 11486–11497. Published online 2019 Jun 7. doi: 10.1074/jbc.RA118.007074

PMCID:: PMC6663880

Abstract Article PDF–2.0M

Select item 145936519.

Phosphoproteome analysis of the human mitotic spindle

Marjaana Nousiainen, Herman H. W. Silljé, Guido Sauer, Erich A. Nigg, Roman Körner

Proc Natl Acad Sci U S A. 2006 Apr 4; 103(14): 5391–5396. Published online 2006 Mar 24. doi: 10.1073/pnas.0507066103

PMCID:: PMC1459365

Abstract Article PDF–370K

Select item 787370120.

Global proteomics of Ubqln2-based murine models of ALS

Alexandra M. Whiteley, Miguel A. Prado, Stefanie A.H. de Poot, Joao A. Paulo, Marissa Ashton, Sara Dominguez, Martin Weber, Hai Ngu, John Szpyt, Mark P. Jedrychowski, Amy Easton, Steven P. Gygi, Thimo Kurz, Mervyn J. Monteiro, Eric J. Brown, Daniel Finley

J Biol Chem. 2021 Jan-Jun; 296: 100153. Published online 2020 Dec 10. doi: 10.1074/jbc.RA120.015960

PMCID:: PMC7873701

Abstract Article PDF–3.0M

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