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Select item 57141651.

Novel mechanisms of eIF2B action and regulation by eIF2α phosphorylation

Andrew M. Bogorad, Kai Ying Lin, Assen Marintchev

Nucleic Acids Res. 2017 Nov 16; 45(20): 11962–11979. Published online 2017 Sep 25. doi: 10.1093/nar/gkx845

PMCID:: PMC5714165

Abstract Article PDF–6.9M

Select item 13860202.

The N-terminal domain of the human eIF2β subunit and the CK2 phosphorylation sites are required for its function

Franc Llorens, Anna Duarri, Eduard Sarró, Nerea Roher, Maria Plana, Emilio Itarte

Biochem J. 2006 Feb 15; 394(Pt 1): 227–236. Prepublished online 2005 Oct 14. Published online 2006 Jan 27. doi: 10.1042/BJ20050605

PMCID:: PMC1386020

Abstract Article PDF–527K

Select item 79485053.

Mutational analysis of the alpha subunit of eIF2B provides insights into the role of eIF2B bodies in translational control and VWM disease

Karl Norris, Rachel E. Hodgson, Tawni Dornelles, K. Elizabeth Allen, Ben M. Abell, Mark P. Ashe, Susan G. Campbell

J Biol Chem. 2021 Jan-Jun; 296: 100207. Published online 2021 Jan 30. doi: 10.1074/jbc.RA120.014956

PMCID:: PMC7948505

Abstract Article PDF–3.9M

Select item 45387944.

Mutations in a translation initiation factor identify target of a memory-enhancing compound

Yusuke Sekine, Alisa Zyryanova, Ana Crespillo-Casado, Peter M. Fischer, Heather P. Harding, David Ron

Science. Author manuscript; available in PMC 2015 Nov 29.

Published in final edited form as: Science. 2015 May 29; 348(6238): 1027–1030. Published online 2015 Apr 9. doi: 10.1126/science.aaa6986

PMCID:: PMC4538794

Abstract Article PDF–994K

Select item 11803145.

Ovarian Failure Related to Eukaryotic Initiation Factor 2B Mutations

Anne Fogli, Diana Rodriguez, Eléonore Eymard-Pierre, Françoise Bouhour, Pierre Labauge, Brandon F. Meaney, Susan Zeesman, Christine R. Kaneski, Raphael Schiffmann, Odile Boespflug-Tanguy

Am J Hum Genet. 2003 Jun; 72(6): 1544–1550. Published online 2003 Apr 21. doi: 10.1086/375404

PMCID:: PMC1180314

Abstract Article PDF–209K

Select item 31964366.

The Alpha Subunit of Eukaryotic Initiation Factor 2B (eIF2B) Is Required for eIF2-Mediated Translational Suppression of Vesicular Stomatitis Virus

Rachel Elsby, Joshua F. Heiber, Peter Reid, Scot R. Kimball, Graham D. Pavitt, Glen N. Barber

J Virol. 2011 Oct; 85(19): 9716–9725. doi: 10.1128/JVI.05146-11

PMCID:: PMC3196436

Abstract Article PDF–1.7M

Select item 5294547.

Screening for known mutations in EIF2B genes in a large panel of patients with premature ovarian failure

Anne Fogli, Fernande Gauthier-Barichard, Raphael Schiffmann, Vien H Vanderhoof, Vladimir K Bakalov, Lawrence M Nelson, Odile Boespflug-Tanguy

BMC Womens Health. 2004; 4: 8. Published online 2004 Oct 26. doi: 10.1186/1472-6874-4-8

PMCID:: PMC529454

Abstract Article PDF–223K

Select item 11804998.

Marjo S. van der Knaap, Carola G. M. van Berkel, Jochen Herms, Rudy van Coster, Martina Baethmann, Sakkubai Naidu, Eugen Boltshauser, Michèl A. A. P. Willemsen, Barbara Plecko, Georg F. Hoffmann, Christopher G. Proud, Gert C. Scheper, Jan C. Pronk

Am J Hum Genet. 2003 Nov; 73(5): 1199–1207. Published online 2003 Oct 17. doi: 10.1086/379524

PMCID:: PMC1180499

Abstract Article PDF–411K

Select item 3558569.

Mutations Causing Childhood Ataxia with Central Nervous System Hypomyelination Reduce Eukaryotic Initiation Factor 2B Complex Formation and Activity

Jonathan P. Richardson, Sarah S. Mohammad, Graham D. Pavitt

Mol Cell Biol. 2004 Mar; 24(6): 2352–2363. doi: 10.1128/MCB.24.6.2352-2363.2004

PMCID:: PMC355856

Abstract Article PDF–558K

Select item 12278210.

Modulation of protein translation by Nck-1

Sem Kebache, Dongmei Zuo, Eric Chevet, Louise Larose

Proc Natl Acad Sci U S A. 2002 Apr 16; 99(8): 5406–5411. doi: 10.1073/pnas.082483399

PMCID:: PMC122782

Abstract Article PDF–331K

Select item 23166211.

Identification of a regulatory subcomplex in the guanine nucleotide exchange factor eIF2B that mediates inhibition by phosphorylated eIF2.

W Yang, A G Hinnebusch

Mol Cell Biol. 1996 Nov; 16(11): 6603–6616. doi: 10.1128/mcb.16.11.6603

PMCID:: PMC231662

Summary PDF–2.0M

Select item 38166412.

Mutations Linked to Leukoencephalopathy with Vanishing White Matter Impair the Function of the Eukaryotic Initiation Factor 2B Complex in Diverse Ways

Wei Li, Xuemin Wang, Marjo S. van der Knaap, Christopher G. Proud

Mol Cell Biol. 2004 Apr; 24(8): 3295–3306. doi: 10.1128/MCB.24.8.3295-3306.2004

PMCID:: PMC381664

Abstract Article PDF–473K

Select item 818910013.

Transmembrane receptor DCC associates with protein synthesis machinery and regulates translation

Joseph Tcherkezian, Perry A. Brittis, Franziska Thomas, Philippe P. Roux, John G. Flanagan

Cell. Author manuscript; available in PMC 2021 Jun 9.

Published in final edited form as: Cell. 2021 Apr 29; 184(9): 2520. doi: 10.1016/j.cell.2021.04.018

Corrects:: Cell. 2010 May 14; 141(4): 632–644.

PMCID:: PMC8189100

Correction PDF–376K

Select item 8575314.

Identification of Domains and Residues within the ɛ Subunit of Eukaryotic Translation Initiation Factor 2B (eIF2Bɛ) Required for Guanine Nucleotide Exchange Reveals a Novel Activation Function Promoted by eIF2B Complex Formation

Edith Gomez, Graham D. Pavitt

Mol Cell Biol. 2000 Jun; 20(11): 3965–3976. doi: 10.1128/mcb.20.11.3965-3976.2000

PMCID:: PMC85753

Abstract Article PDF–2.5M

Select item 483382515.

Expression, purification, and crystallization of Schizosaccharomyces pombe eIF2B

Kazuhiro Kashiwagi, Tomoaki Shigeta, Hiroaki Imataka, Takuhiro Ito, Shigeyuki Yokoyama

J Struct Funct Genomics. 2016; 17: 33–38. Published online 2016 Mar 29. doi: 10.1007/s10969-016-9203-3

PMCID:: PMC4833825

Abstract Article PDF–1.0M

Select item 288159416.

Transmembrane receptor DCC associates with protein synthesis machinery and regulates translation

Joseph Tcherkezian, Perry A. Brittis, Franziska Thomas, Philippe P. Roux, John G. Flanagan

Cell. Author manuscript; available in PMC 2011 May 14.

Published in final edited form as: Cell. 2010 May 14; 141(4): 632–644. Published online 2010 Apr 29. doi: 10.1016/j.cell.2010.04.008

Correction in:: Cell. 2021 Apr 29; 184(9): 2520.

PMCID:: PMC2881594

Abstract Article PDF–4.4M

Select item 224738117.

Proteomic and functional analysis of Argonaute-containing mRNA–protein complexes in human cells

Julia Höck, Lasse Weinmann, Christine Ender, Sabine Rüdel, Elisabeth Kremmer, Monika Raabe, Henning Urlaub, Gunter Meister

EMBO Rep. 2007 Nov; 8(11): 1052–1060. Published online 2007 Oct 12. doi: 10.1038/sj.embor.7401088

PMCID:: PMC2247381

Abstract Article PDF–285K

Select item 631799418.

SNIP1 Recruits TET2 to Regulate c-MYC Target Genes and Cellular DNA Damage Response

Lei-Lei Chen, Huai-Peng Lin, Wen-Jie Zhou, Chen-Xi He, Zhi-Yong Zhang, Zhou-Li Cheng, Jun-Bin Song, Peng Liu, Xin-Yu Chen, Yu-Kun Xia, Xiu-Fei Chen, Ren-Qiang Sun, Jing-Ye Zhang, Yi-Ping Sun, Lei Song, Bing-Jie Liu, Rui-Kai Du, Chen Ding, Fei Lan, Sheng-Lin Huang, Feng Zhou, Suling Liu, Yue Xiong, Dan Ye, Kun-Liang Guan

Cell Rep. Author manuscript; available in PMC 2019 Jan 3.

Published in final edited form as: Cell Rep. 2018 Nov 6; 25(6): 1485–1500.e4. doi: 10.1016/j.celrep.2018.10.028

PMCID:: PMC6317994

Abstract Article PDF–1.4M

Select item 401998119.

Interaction proteome of human Hippo signaling: modular control of the co‐activator YAP1

Simon Hauri, Alexander Wepf, Audrey van Drogen, Markku Varjosalo, Nic Tapon, Ruedi Aebersold, Matthias Gstaiger

Mol Syst Biol. 2013; 9: 713. Published online 2013 Dec 20. doi: 10.1002/msb.201304750

PMCID:: PMC4019981

Abstract Article PDF–915K

Select item 296729720.

A large-scale candidate-gene association study of age at menarche and age at natural menopause

Chunyan He, Peter Kraft, Daniel I. Chasman, Julie E. Buring, Constance Chen, Susan E. Hankinson, Guillaume Paré, Stephen Chanock, Paul M. Ridker, David J. Hunter

Hum Genet. Author manuscript; available in PMC 2010 Nov 1.

Published in final edited form as: Hum Genet. 2010 Nov; 128(5): 515–527. Published online 2010 Aug 24. doi: 10.1007/s00439-010-0878-4

PMCID:: PMC2967297

Abstract Article PDF–84K

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