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Select item 109457361.

Heparan sulfate promotes TRAIL-induced tumor cell apoptosis

Yin Luo, Huanmeng Hao, Zhangjie Wang, Chih Yean Ong, Robert Dutcher, Yongmei Xu, Jian Liu, Lars C Pedersen, Ding Xu

eLife. 2024; 12: RP90192. Published online 2024 Jan 24. doi: 10.7554/eLife.90192

PMCID:: PMC10945736

Abstract Article PDF–6.5M

Select item 98378342.

An enhancer variant associated with breast cancer susceptibility in Black women regulates TNFSF10 expression and antitumor immunity in triple-negative breast cancer

Yoo Jane Han, Jing Zhang, Ashley Hardeman, Margaret Liu, Olga Karginova, Roger Romero, Galina F Khramtsova, Yonglan Zheng, Dezheng Huo, Olufunmilayo I Olopade

Hum Mol Genet. 2023 Jan 1; 32(1): 139–150. Published online 2022 Aug 5. doi: 10.1093/hmg/ddac168

PMCID:: PMC9837834

Abstract Article PDF–1.7M

Select item 93464913.

Engagement of TRAIL triggers degranulation and IFNγ production in human natural killer cells

Johannes Höfle, Timo Trenkner, Nadja Kleist, Vera Schwane, Sarah Vollmers, Bryan Barcelona, Annika Niehrs, Pia Fittje, Van Hung Huynh‐Tran, Jürgen Sauter, Alexander H Schmidt, Sven Peine, Angelique Hoelzemer, Laura Richert, Marcus Altfeld, Christian Körner

EMBO Rep. 2022 Aug; 23(8): e54133. Published online 2022 Jun 27. doi: 10.15252/embr.202154133

PMCID:: PMC9346491

Abstract Article PDF–10M

Select item 87504414.

TRAIL Triggers CRAC-Dependent Calcium Influx and Apoptosis through the Recruitment of Autophagy Proteins to Death-Inducing Signaling Complex

Kelly Airiau, Pierre Vacher, Olivier Micheau, Valerie Prouzet-Mauleon, Guido Kroemer, Mohammad Amin Moosavi, Mojgan Djavaheri-Mergny

Cells. 2022 Jan; 11(1): 57. Published online 2021 Dec 25. doi: 10.3390/cells11010057

PMCID:: PMC8750441

Abstract Article PDF–2.6M

Select item 87066835.

Low-Level Endothelial TRAIL-Receptor Expression Obstructs the CNS-Delivery of Angiopep-2 Functionalised TRAIL-Receptor Agonists for the Treatment of Glioblastoma

Nivetha Krishna Moorthy, Oliver Seifert, Stephan Eisler, Sara Weirich, Roland E. Kontermann, Markus Rehm, Gavin Fullstone

Molecules. 2021 Dec; 26(24): 7582. Published online 2021 Dec 14. doi: 10.3390/molecules26247582

PMCID:: PMC8706683

Abstract Article PDF–4.7M

Select item 85632866.

TRAIL signaling promotes entosis in colorectal cancer

Emir Bozkurt, Heiko Düssmann, Manuela Salvucci, Brenton L. Cavanagh, Sandra Van Schaeybroeck, Daniel B. Longley, Seamus J. Martin, Jochen H.M. Prehn

J Cell Biol. 2021 Nov 1; 220(11): e202010030. Published online 2021 Sep 21. doi: 10.1083/jcb.202010030

PMCID:: PMC8563286

Abstract Article PDF–8.1M

Select item 83517107.

LncRNA AC079630.4 expression associated with the progression and prognosis in lung cancer

Li-Fang Wang, Li-Ping Wu, Jian-Dong Wen

Aging (Albany NY) 2021 Jul 31; 13(14): 18658–18668. Published online 2021 Jul 19. doi: 10.18632/aging.203310

PMCID:: PMC8351710

Abstract Article PDF–1.0M

Select item 79774538.

Combination of long-acting TRAIL and tumor cell-targeted photodynamic therapy as a novel strategy to overcome chemotherapeutic multidrug resistance and TRAIL resistance of colorectal cancer

Tianshan She, Qiuxiao Shi, Zhao Li, Yanru Feng, Hao Yang, Ze Tao, Heng Li, Jie Chen, Shisheng Wang, Yan Liang, Jingqiu Cheng, Xiaofeng Lu

Theranostics. 2021; 11(9): 4281–4297. Published online 2021 Feb 25. doi: 10.7150/thno.51193

PMCID:: PMC7977453

Abstract Article PDF–3.1M

Select item 79614459.

TRAIL Mediates Neuronal Death in AUD: A Link between Neuroinflammation and Neurodegeneration

Liya Qin, Jian Zou, Alexandra Barnett, Ryan P. Vetreno, Fulton T. Crews, Leon G. Coleman, Jr.

Int J Mol Sci. 2021 Mar; 22(5): 2547. Published online 2021 Mar 4. doi: 10.3390/ijms22052547

PMCID:: PMC7961445

Abstract Article PDF–18M

Select item 778485310.

TRAIL regulates T cell activation and suppresses inflammation in autoimmune diseases

I-Tsu Chyuan, Ping-Ning Hsu

Cell Mol Immunol. 2020 Dec; 17(12): 1281–1283. Published online 2020 Mar 24. doi: 10.1038/s41423-020-0410-2

PMCID:: PMC7784853

Article PDF–1.0M

Select item 767211011.

Designed ferritin nanocages displaying trimeric TRAIL and tumor-targeting peptides confer superior anti-tumor efficacy

Jae Do Yoo, Sang Mun Bae, Junyoung Seo, In Seon Jeon, Sri Murugan Poongkavithai Vadevoo, Sang-Yeob Kim, In-San Kim, Byungheon Lee, Soyoun Kim

Sci Rep. 2020; 10: 19997. Published online 2020 Nov 17. doi: 10.1038/s41598-020-77095-x

PMCID:: PMC7672110

Abstract Article PDF–6.7M

Select item 764202712.

Human cancers express TRAILshort, a dominant negative TRAIL splice variant, which impairs immune effector cell killing of tumor cells.

Fatma Aboulnasr, Ashton Krogman, Rondell P. Graham, Nathan W. Cummins, Anisha Misra, Enrique Garcia-Rivera, Jeff R. Anderson, Sekar Natesampillai, Nicole Kogan, Murali Aravamudan, Zilin Nie, Thomas D. Y. Chung, Richard Buick, Andrew L. Feldman, Rebecca L. King, Anne J. Novak, Stephen M. Ansell, Saad Kenderian, Andrew D. Badley

Clin Cancer Res. Author manuscript; available in PMC 2021 May 1.

Published in final edited form as: Clin Cancer Res. 2020 Nov 1; 26(21): 5759–5771. Published online 2020 Jul 15. doi: 10.1158/1078-0432.CCR-20-0251

PMCID:: PMC7642027

Abstract Article PDF–2.4M

Select item 731701413.

HTNV Sensitizes Host Toward TRAIL-Mediated Apoptosis—A Pivotal Anti-hantaviral Role of TRAIL

Qing-Zhou Chen, Xin Wang, Fan Luo, Ning Li, Ni Zhu, Shuang Lu, Yu-xing Zan, Chao-Jie Zhong, Mei-Rong Wang, Hai-Tao Hu, Yong-Zhen Zhang, Hai-Rong Xiong, Wei Hou

Front Immunol. 2020; 11: 1072. Published online 2020 Jun 19. doi: 10.3389/fimmu.2020.01072

PMCID:: PMC7317014

Abstract Article PDF–11M

Select item 730804614.

Identification of pathogenic TRAIL-expressing innate immune cells during HIV-1 infection in humanized mice by scRNA-Seq

Liang Cheng, Haisheng Yu, John A. Wrobel, Guangming Li, Peng Liu, Zhiyuan Hu, Xiao-Ning Xu, Lishan Su

JCI Insight. 2020 Jun 4; 5(11): e135344. Published online 2020 Jun 4. doi: 10.1172/jci.insight.135344

PMCID:: PMC7308046

Abstract Article PDF–8.4M

Select item 718341815.

Regulation of pancreatic cancer TRAIL resistance by protein O-GlcNAcylation

Shan-zhong Yang, Fei Xu, Kaiyu Yuan, Yong Sun, Tong Zhou, Xinyang Zhao, Jay M McDonald, Yabing Chen

Lab Invest. Author manuscript; available in PMC 2020 Jul 2.

Published in final edited form as: Lab Invest. 2020 May; 100(5): 777–785. Published online 2020 Jan 2. doi: 10.1038/s41374-019-0365-z

PMCID:: PMC7183418

Abstract Article PDF–1.1M

Select item 718183016.

Enhancing the antitumor activity of an engineered TRAIL-coated oncolytic adenovirus for treating acute myeloid leukemia

Zixuan Wang, Wenmo Liu, Lizheng Wang, Peng Gao, Zhe Li, Jiaxin Wu, Haihong Zhang, Hui Wu, Wei Kong, Bin Yu, Xianghui Yu

Signal Transduct Target Ther. 2020; 5: 40. Published online 2020 Apr 24. doi: 10.1038/s41392-020-0135-9

PMCID:: PMC7181830

Abstract Article PDF–3.8M

Select item 710965417.

Functional Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand Production by Avian Influenza Virus–Infected Macrophages

Jianfang Zhou, Helen K. W. Law, Chung Yan Cheung, Iris H. Y. Ng, J. S. Malik Peiris, Yu Lung Lau

J Infect Dis. 2006 Apr 1; 193(7): 945–953. Published online 2006 Apr 1. doi: 10.1086/500954

PMCID:: PMC7109654

Abstract Article PDF–687K

Select item 687346218.

HIV Elite Control is associated with reduced TRAILshort expression

Ana C. PAIM, Nathan W. CUMMINS, Sekar NATESAMPILLAI, Enrique GARCIA-RIVERA, Nicole KOGAN, Ujjwal NEOGI, Anders SÖNNERBORG, Maike SPERK, Gary D. BREN, Steve DEEKS, Eric POLLEY, Andrew D. BADLEY

AIDS. Author manuscript; available in PMC 2019 Nov 22.

Published in final edited form as: AIDS. 2019 Sep 1; 33(11): 1757–1763. doi: 10.1097/QAD.0000000000002279

PMCID:: PMC6873462

Abstract Article PDF–700K

Select item 678503619.

TRAILshort protects against CD4 T cell death during acute HIV infection.

Sekar Natesampillai, Ana C. Paim, Nathan W. Cummins, Aswath P. Chandrasekar, Gary D. Bren, Sharon R. Lewin, Hans-Peter Kiem, Andrew D. Badley

J Immunol. Author manuscript; available in PMC 2020 Aug 1.

Published in final edited form as: J Immunol. 2019 Aug 1; 203(3): 718–724. Published online 2019 Jun 12. doi: 10.4049/jimmunol.1900271

PMCID:: PMC6785036

Abstract Article PDF–702K

Select item 664900620.

Preliminary clinical measurement of the expression of TNF‐related apoptosis inducing ligand in patients with ankylosing spondylitis

Yang Zai‐Xing, Liang Yan, Wang Hao, Zhu Ye, Li Chang, Zhong Ren‐Qian

J Clin Lab Anal. 2008; 22(2): 138–145. Published online 2008 Mar 17. doi: 10.1002/jcla.20231

PMCID:: PMC6649006

Abstract Article PDF–307K

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